Invitro myelotoxicity assessment of the emerging mycotoxins Beauvericin, Enniatin b and Moniliformin on human hematopoietic progenitors

Toxicon

Volumn 59, Issue 1, 2012, Pages 182-191

  Ficheux, A S ^a   Sibiril, Y ^a   Le Garrec, R ^a   Parent Massin, D ^a  

^a UNIVERSITÉ EUROPÉENNE DE BRETAGNE   (France)

Author keywords

Beauvericin; Emerging mycotoxins; Enniatin b; Human hematopoietic progenitors; Moniliformin; Myelotoxicity

Indexed keywords

BEAUVERICIN; ENNIATIN; MONILIFORMIN; CYCLOBUTANE DERIVATIVE; DEPSIPEPTIDE; ENNIATINS; MYCOTOXIN;

ARTICLE; BONE MARROW TOXICITY; BURST FORMING UNIT E; CELL PROLIFERATION; COLONY FORMING UNIT; COLONY FORMING UNIT GM; COLONY FORMING UNIT MK; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY TEST; ERYTHROID PRECURSOR CELL; FUSARIUM; GRANULOCYTE PRECURSOR; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MEGAKARYOBLAST; MIGRATION INHIBITION; PRIORITY JOURNAL; TOXIN STRUCTURE; CELL CULTURE; CHEMISTRY; DRUG EFFECT; HEMATOPOIETIC STEM CELL; TOXICITY TESTING;

CELLS, CULTURED; CYCLOBUTANES; DEPSIPEPTIDES; HEMATOPOIETIC STEM CELLS; HUMANS; MYCOTOXINS; TOXICITY TESTS;

EID: 82455171829     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2011.11.006     Document Type: Article

References (46)

1. Behm C., Degen G.H., Föllmann W. The Fusarium toxin enniatin B exerts no genotoxic activity, but pronounced cytotoxicity invitro. Mol. Nutr. Food Res. 2009, 53:423-430.
2. Bennett J.W., Klich M. Mycotoxins. Clin. Microbiol. Rev. 2003, 16:497-516.
3. Calo L., Fornelli F., Ramires R., Nenna S., Tursi A., Caiaffa M.F., Macchia L. Cytotoxic effects of the mycotoxin Beauvericin to human cell lines of myeloid origin. Pharmacol. Res. 2004, 49:73-77.
4. Dombrink-Kurtzman M.A. Fumonisin and beauvericin induce apoptosis in turkey peripheral blood lymphocytes. Mycopathologia 2003, 156:357-364.
5. Froquet R., Le Dréan G., Parent-Massin D. Effect of ochratoxin A on human haematopoietic progenitors proliferation and differentiation: an invitro study. Hum. Exp. Toxicol. 2003, 22:393-400.
6. Froquet R., Sibiril Y., Parent-Massin D. Trichothecene toxicity on human megakaryocyte progenitors (CFU-MK). Hum. Exp. Toxicol. 2001, 20:84-89.
7. Ivanova L., Skerve E., Eriksen G., Uhlig S. Cytotoxicity of Enniatins A, A1, B, B1, B2 and B3 from Fusarium avenaceum. Toxicon 2006, 47:868-876.
8. Jestoi M. Emerging Fusarium-Mycotoxins Fusaproliferin, Beauvericin, Enniatins, and Moniliformin - a review. Crit. Rev. Food Sci. Nutr. 2008, 48:21-49.
9. Jestoi M., Rokka M., Yli-Mattila T., Parikka P., Rizzo A., Peltonen K. Presence and concentrations of the Fusarium-related mycotoxins Beauvericin, Enniatins and Moniliformin in Finnish grain samples. Food Addit. Contam. 2004, 21:794-802.
10. Jow G.M., Chou C.J., Chen B.F., Tsai J.H. Beauvericin induces cytotoxic effects in human acute lymphoblastic leukemia cells through cytochrome c release, caspase 3 activation: the causative role of calcium. Cancer Lett. 2004, 216:165-173.
11. Klaric M.S., Darabos D., Rozgaj R., Kasuba V., Pepeljnjak S. Beauvericin and ochratoxin A genotoxicity evaluated using the alkaline comet assay: single and combined genotoxic action. Arch. Toxicol. 2010, 84:641-650.
12. Klaric M.S., Pepeljnjak S., Rozgaj R. Genotoxicity of Fumonisin B1, Beauvericin and Ochratoxin A in porcine kidney PK15 cells: effects of individual and combined treatment. Croat. Chem. Acta 2008, 81:139-146.
13. Klaric M.S., Rumora L., Ljubanovic D., Pepeljnjak S. Cytotoxicity and apoptosis induced by fumonisin B1, Beauvericin and ochratoxin A in porcine kidney PK15 cells: effects of individual and combined treatment. Arch. Toxicol. 2008, 82:247-255.
14. Kokkonen M., Ojala L., Parikka P., Jestoi M. Mycotoxin production of selected Fusarium species at different culture conditions. Int. J. Food Microbiol. 2010, 143:17-25.
15. Kouri K., Lemmens M., Lemmens-Gruber R. Beauvericin-induced channels in ventricular myocytes and liposomes. Biochim. Biophys. Acta 2003, 1609:203-210.
16. Lautraite S., Parent-Massin D., Rio B., Hoellinger H. Comparison of toxicity induced by T-2 toxin on human and rat granulo-monocytic progenitors with an invitro model. Hum. Exp. Toxicol. 1995, 14:672-678.
17. Lautraite S., Parent-Massin D., Rio B., Hoellinger H. Comparison of toxicity induced by HT-2 toxin on human and rat granulo-monocytic progenitors with an invitro model. Hum. Exp. Toxicol. 1996, 15:208-213.
18. Lautraite S., Parent-Massin D., Rio B., Hoellinger H. Invitro toxicity induced by deoxynivalenol (DON) on human and rat granulo-monocytic progenitors. Cell Biol. Toxicol. 1997, 175-183.
19. Lautraite S., Rio B., Guinard J., Parent-Massin D. Invitro effects of diacetoxyscirpenol (DAS) on human and rat granulo-monocytic progenitors. Mycopathologia 1997, 140:59-64.
20. Ledoux D.R., Broomhead J.N., Bermudez A.J., Rottinghaus G.E. Individual and combined effects of the Fusarium mycotoxins fumonisin B1 and Moniliformin in broiler chicks. Avian Dis. 2003, 47:1368-1375.
21. Logrieco A., Moretti A., Castella G., Kostecki M., Golinski P., Ritieni A., Chelkowski J. Beauvericin production by Fusarium species. Appl. Environ. Microbiol. 1998, 64:3084-3088.
22. Logrieco A., Rizzo A., Ferracane R., Ritieni A. Occurrence of Beauvericin and Enniatins in wheat affected by Fusarium avenaceum head blight. Appl. Environ. Microbiol. 2002, 68:82-85.
23. Meca G., Font G., Ruiz M.J. Comparative cytotoxicity study of enniatins A, A1, A2, B, B1, B4 and J3 on Caco-2 cells, Hep-G2 and HT-29. Food Chem. Toxicol. 2011, 49:2464-2469.
24. Meca G., Soriano J.M., Gaspari A., Ritieni A., Moretti A., Manes J. Antifungal effects of the bioactive compounds Enniatins A, A1, B, B1. Toxicon 2010, 56:480-485.
25. Meca G., Zinedine A., Blesa J., Font G., Mañes J. Further data on the presence of Fusarium emerging mycotoxins Enniatins, fusaproliferin and Beauvericin in cereals available on the Spanish markets. Food Chem. Toxicol. 2010, 48:1412-1416.
26. Ojcius D.M., Zychlinsky A., Zheng L.M., Young J.D.E. Ionophore-induced apoptosis: role of DNA fragmentation and calcium fluxes. Exp. Cell Res. 1991, 197:43-49.
27. Paterson R.R., Lima N. Toxicology of mycotoxins. EXS 2010, 2:31-63.
28. Pessina A., Albella B., Bueren J., Brantom P., Casati S., Gribaldo L., Croera C., Gagliardi G., Foti P., Parchment R., Parent-Massin D., Sibiril Y., Schoeters G., Van Den Heuvel R. Prevalidation of a model for predicting acute neutropenia by colony forming unit granulocyte/macrophage (CFU-GM) assay. Toxicol. InVitro 2001, 15:729-740.
29. Pessina A., Parent-Massin D., Albella B., Van Den Heuvel R., Casati S., Croera C., Malerba I., Sibiril Y., Gomez S., de Smedt A., Gribaldo L. Application of human CFU-Mk assay to predict potential thrombocytotoxicity of drugs. Toxicol. InVitro 2009, 23:194-200.
30. Rio B., Lautraite S., Parent-Massin D. Invitro toxicity of trichothecenes on human erythroblastic progenitors. Hum. Exp. Toxicol. 1997, 16:673-679.
31. Ritieni A., Moretti A., Logrieco A., Bottalico A., Randazzo G., Monti S.M., Ferracane R., Fogliano V. Occurrence of fusaproliferin, fumonisin B1 and beauvericin in maize from Italy. J. Agric. Food Chem. 1997, 45:4011-4016.
32. Ruiz M.J., Franzova P., Juan-García A., Font G. Toxicological interactions between the mycotoxins beauvericin, deoxynivalenol and T-2 toxin in CHO-K1 cells invitro. Toxicon 2011, 58:315-326.
33. Ruiz M.J., Macáková P., Juan-García A., Font G. Cytotoxic effects of mycotoxin combinations in mammalian kidney cells. Food Chem. Toxicol. 2011, 49:2718-2724.
34. Sharman M., Gilbert J., Chelkowski J. A survey of the occurrence of the mycotoxin Moniliformin in cereal samples from sources worldwide. Food Addit. Contam. 1991, 84:459-466.
35. Sorensen J.L., Nielsen K.F., Rasmussen P.H., Thrane U. Development of a LC-MS/MS method for the analysis of Enniatins and Beauvericin in whole fresh and ensiled maize. J. Agric. Food Chem. 2008, 56:10439-10443.
36. Sorensen J.L., Nielsen K.F., Thrane U. Analysis of Moniliformin in maize plants using hydrophilic interaction chromatography. J. Agric. Food Chem. 2007, 55:9764-9768.
37. Syed M., Kucherenko Q.Y., Lang F. Beauvericin induced erythrocyte cell membrane scrambling. Toxicology 2011, 283:24-31.
38. Thrane U., Adler A., Clasen P.E., Galvano F., Langseth W., Lew H., Logrieco A., Nielsen K.F., Ritieni A. Diversity in metabolite production by Fusarium langsethiae, Fusarium poae, and Fusarium sporotrichioides. Int. J. Food Microbiol. 2004, 95:257-266.
39. Tomoda H., Huang X.-H., Cao J., Nishida H., Nagao R., Okuda S., Tanaka H., Omura S., Arai H., Inoue K. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J. Antibiot. 1992, 45:1626-1632.
40. Uhlig S., Torp M., Heier B.T. Beauvericin and Enniatin A, A1, B and B1 in Norwegian grain: a survey. Food Chem. 2006, 94:193-201.
41. Uhlig S., Torp M., Jarp J., Parich A., Gutleb A.C., Krska R. Moniliformin in Norwegian grain. Food Addit. Contam. 2004, 21:598-606.
42. Visconti A., Minervini F., Lucivero G., Gambatesa V. Cytotoxic and immunotoxic effects of Fusarium mycotoxins using a rapid colorimetric bioassay. Mycopathologia 1991, 113:181-186.
43. Vogelgsang S., Sulyok M., Banziger I., Krska R., Schuhmacher, Forrer H.R. Effect of fungal strain and cereal substrate on invitro mycotoxin production by Fusarium poae and Fusarium avenaceum. Food Addit. Contam. 2008, 25:745-757.
44. Waskiewicz A., Golinski P., Karolewski Z., Irzykowska L., Bocianowski J., Kostecki M., Weber Z. Formation of fumonisins and other secondary metabolites by Fusarium oxysporum and F. proliferatum: a comparative study. Food Addit. Contam. 2010, 5:608-615.
45. Wu W., Liu T., Vesonder R.F. Comparative cytotoxicity of fumonisin B1 and Moniliformin in chicken primary cell cultures. Mycopathologia 1995, 132:111-116.
46. Yu S.R., Liu X.J., Wang Y.H., Liu J. A survey of Moniliformin contamination in rice and corn from Keshan disease endemic and non-KSD areas in China. Biomed. Environ. Sci. 1995, 8:330-334.