-
1
-
-
0036852712
-
Pharmacological prevention of Parkinson disease in Drosophila
-
Auluck P.K., Bonini N.M. Pharmacological prevention of Parkinson disease in Drosophila. Nat Med 2002, 8:1185-1186.
-
(2002)
Nat Med
, vol.8
, pp. 1185-1186
-
-
Auluck, P.K.1
Bonini, N.M.2
-
2
-
-
0033646279
-
Effects of FKBP-12 ligands following tibial nerve injury in rats
-
Becker D.B., Jensen J.N., Myckatyn T.M., Doolabh V.B., Hunter D.A., Mackinnon S.E. Effects of FKBP-12 ligands following tibial nerve injury in rats. J Reconstr Microsurg 2000, 16:613-620.
-
(2000)
J Reconstr Microsurg
, vol.16
, pp. 613-620
-
-
Becker, D.B.1
Jensen, J.N.2
Myckatyn, T.M.3
Doolabh, V.B.4
Hunter, D.A.5
Mackinnon, S.E.6
-
3
-
-
36248934262
-
Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury
-
Boivin A., Pineau I., Barrette B., Filali M., Vallieres N., Rivest S., Lacroix S. Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury. J Neurosci 2007, 27:12565-12576.
-
(2007)
J Neurosci
, vol.27
, pp. 12565-12576
-
-
Boivin, A.1
Pineau, I.2
Barrette, B.3
Filali, M.4
Vallieres, N.5
Rivest, S.6
Lacroix, S.7
-
4
-
-
18744394342
-
Abortive myogenesis in denervated skeletal muscle: differentiative properties of satellite cells, their migration, and block of terminal differentiation
-
Borisov A.B., Dedkov E.I., Carlson B.M. Abortive myogenesis in denervated skeletal muscle: differentiative properties of satellite cells, their migration, and block of terminal differentiation. Anat Embryol (Berl) 2005, 209:269-279.
-
(2005)
Anat Embryol (Berl)
, vol.209
, pp. 269-279
-
-
Borisov, A.B.1
Dedkov, E.I.2
Carlson, B.M.3
-
5
-
-
24344471385
-
Differentiation of activated satellite cells in denervated muscle following single fusions in situ and in cell culture
-
Borisov A.B., Dedkov E.I., Carlson B.M. Differentiation of activated satellite cells in denervated muscle following single fusions in situ and in cell culture. Histochem Cell Biol 2005, 124:13-23.
-
(2005)
Histochem Cell Biol
, vol.124
, pp. 13-23
-
-
Borisov, A.B.1
Dedkov, E.I.2
Carlson, B.M.3
-
6
-
-
1642396949
-
Delayed nerve repair is associated with diminished neuroenhancement by FK506
-
Brenner M.J., Fox I.K., Kawamura D.H., Yu V.M., Lowe J.B., Hunter D.A., Mackinnon S.E. Delayed nerve repair is associated with diminished neuroenhancement by FK506. Laryngoscope 2004, 114:570-576.
-
(2004)
Laryngoscope
, vol.114
, pp. 570-576
-
-
Brenner, M.J.1
Fox, I.K.2
Kawamura, D.H.3
Yu, V.M.4
Lowe, J.B.5
Hunter, D.A.6
Mackinnon, S.E.7
-
7
-
-
0036799493
-
The spectrum of complications of immunosuppression: is the time right for hand transplantation?
-
Brenner MJ, Tung TH, Jensen JN, Mackinnon SE (2002) The spectrum of complications of immunosuppression: is the time right for hand transplantation? J Bone Joint Surg Am 84-A:1861-1870.
-
(2002)
J Bone Joint Surg Am
, vol.84 A
, pp. 1861-1870
-
-
Brenner, M.J.1
Tung, T.H.2
Jensen, J.N.3
Mackinnon, S.E.4
-
8
-
-
0026683408
-
Consequences of slow Wallerian degeneration for regenerating motor and sensory axons
-
Brown M.C., Lunn E.R., Perry V.H. Consequences of slow Wallerian degeneration for regenerating motor and sensory axons. J Neurobiol 1992, 23:521-536.
-
(1992)
J Neurobiol
, vol.23
, pp. 521-536
-
-
Brown, M.C.1
Lunn, E.R.2
Perry, V.H.3
-
9
-
-
0033817543
-
Geldanamycin, an inhibitor of heat shock protein 90 (Hsp90) mediated signal transduction has anti-inflammatory effects and interacts with glucocorticoid receptor in vivo
-
Bucci M., Roviezzo F., Cicala C., Sessa W.C., Cirino G. Geldanamycin, an inhibitor of heat shock protein 90 (Hsp90) mediated signal transduction has anti-inflammatory effects and interacts with glucocorticoid receptor in vivo. Br J Pharmacol 2000, 131:13-16.
-
(2000)
Br J Pharmacol
, vol.131
, pp. 13-16
-
-
Bucci, M.1
Roviezzo, F.2
Cicala, C.3
Sessa, W.C.4
Cirino, G.5
-
10
-
-
78649315021
-
Modulation of satellite cells in rat facial muscle following denervation and delayed reinnervation
-
Chen D., Chen S., Wang W., Liu F., Zhang C., Zheng H. Modulation of satellite cells in rat facial muscle following denervation and delayed reinnervation. Acta Otolaryngol 2010, 130:1411-1420.
-
(2010)
Acta Otolaryngol
, vol.130
, pp. 1411-1420
-
-
Chen, D.1
Chen, S.2
Wang, W.3
Liu, F.4
Zhang, C.5
Zheng, H.6
-
11
-
-
0037147675
-
Transient osmotic stress facilitates mutant huntingtin aggregation
-
Chun W., Lesort M., Lee M., Johnson G.V. Transient osmotic stress facilitates mutant huntingtin aggregation. Neuroreport 2002, 13:2543-2546.
-
(2002)
Neuroreport
, vol.13
, pp. 2543-2546
-
-
Chun, W.1
Lesort, M.2
Lee, M.3
Johnson, G.V.4
-
12
-
-
0033014586
-
FK506 accelerates functional recovery following nerve grafting in a rat model
-
Doolabh V.B., Mackinnon S.E. FK506 accelerates functional recovery following nerve grafting in a rat model. Plast Reconstr Surg 1999, 103:1928-1936.
-
(1999)
Plast Reconstr Surg
, vol.103
, pp. 1928-1936
-
-
Doolabh, V.B.1
Mackinnon, S.E.2
-
13
-
-
0035109501
-
FK506 rescues peripheral nerve allografts in acute rejection
-
Feng F.Y., Ogden M.A., Myckatyn T.M., Grand A.G., Jensen J.N., Hunter D.A., Mackinnon S.E. FK506 rescues peripheral nerve allografts in acute rejection. J Neurotrauma 2001, 18:217-229.
-
(2001)
J Neurotrauma
, vol.18
, pp. 217-229
-
-
Feng, F.Y.1
Ogden, M.A.2
Myckatyn, T.M.3
Grand, A.G.4
Jensen, J.N.5
Hunter, D.A.6
Mackinnon, S.E.7
-
14
-
-
23644442282
-
Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease
-
Flower T.R., Chesnokova L.S., Froelich C.A., Dixon C., Witt S.N. Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease. J Mol Biol 2005, 351:1081-1100.
-
(2005)
J Mol Biol
, vol.351
, pp. 1081-1100
-
-
Flower, T.R.1
Chesnokova, L.S.2
Froelich, C.A.3
Dixon, C.4
Witt, S.N.5
-
15
-
-
0018864527
-
Time course of the conditioning lesion effect on axonal regeneration
-
Forman D.S., McQuarrie I.G., Labore F.W., Wood D.K., Stone L.S., Braddock C.H., Fuchs D.A. Time course of the conditioning lesion effect on axonal regeneration. Brain Res 1980, 182:180-185.
-
(1980)
Brain Res
, vol.182
, pp. 180-185
-
-
Forman, D.S.1
McQuarrie, I.G.2
Labore, F.W.3
Wood, D.K.4
Stone, L.S.5
Braddock, C.H.6
Fuchs, D.A.7
-
16
-
-
33846320884
-
The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones
-
Fortun J., Verrier J.D., Go J.C., Madorsky I., Dunn W.A., Notterpek L. The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones. Neurobiol Dis 2007, 25:252-265.
-
(2007)
Neurobiol Dis
, vol.25
, pp. 252-265
-
-
Fortun, J.1
Verrier, J.D.2
Go, J.C.3
Madorsky, I.4
Dunn, W.A.5
Notterpek, L.6
-
17
-
-
0029032791
-
Contributing factors to poor functional recovery after delayed nerve repair: prolonged axotomy
-
Fu S.Y., Gordon T. Contributing factors to poor functional recovery after delayed nerve repair: prolonged axotomy. J Neurosci 1995, 15:3876-3885.
-
(1995)
J Neurosci
, vol.15
, pp. 3876-3885
-
-
Fu, S.Y.1
Gordon, T.2
-
18
-
-
0029032791
-
Contributing factors to poor functional recovery after delayed nerve repair: prolonged denervation
-
Fu S.Y., Gordon T. Contributing factors to poor functional recovery after delayed nerve repair: prolonged denervation. J Neurosci 1995, 15:3886-3895.
-
(1995)
J Neurosci
, vol.15
, pp. 3886-3895
-
-
Fu, S.Y.1
Gordon, T.2
-
19
-
-
77249121048
-
Geldanamycin and its anti-cancer activities
-
Fukuyo Y., Hunt C.R., Horikoshi N. Geldanamycin and its anti-cancer activities. Cancer Lett 2010, 290:24-35.
-
(2010)
Cancer Lett
, vol.290
, pp. 24-35
-
-
Fukuyo, Y.1
Hunt, C.R.2
Horikoshi, N.3
-
20
-
-
70449706439
-
Anti-protein aggregation is a potential target for preventing delayed neuronal death after transient ischemia
-
Ge P., Luo Y., Wang H., Ling F. Anti-protein aggregation is a potential target for preventing delayed neuronal death after transient ischemia. Med Hypotheses 2009, 73:994-995.
-
(2009)
Med Hypotheses
, vol.73
, pp. 994-995
-
-
Ge, P.1
Luo, Y.2
Wang, H.3
Ling, F.4
-
21
-
-
2342597809
-
Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury
-
Giffard R.G., Xu L., Zhao H., Carrico W., Ouyang Y., Qiao Y., Sapolsky R., Steinberg G., Hu B., Yenari M.A. Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury. J Exp Biol 2004, 207:3213-3220.
-
(2004)
J Exp Biol
, vol.207
, pp. 3213-3220
-
-
Giffard, R.G.1
Xu, L.2
Zhao, H.3
Carrico, W.4
Ouyang, Y.5
Qiao, Y.6
Sapolsky, R.7
Steinberg, G.8
Hu, B.9
Yenari, M.A.10
-
22
-
-
0031309575
-
FK506 and the role of immunophilins in nerve regeneration
-
Gold B.G. FK506 and the role of immunophilins in nerve regeneration. Mol Neurobiol 1997, 15:285-306.
-
(1997)
Mol Neurobiol
, vol.15
, pp. 285-306
-
-
Gold, B.G.1
-
23
-
-
0032776433
-
FK506 and the role of the immunophilin FKBP-52 in nerve regeneration
-
Gold B.G. FK506 and the role of the immunophilin FKBP-52 in nerve regeneration. Drug Metab Rev 1999, 31:649-663.
-
(1999)
Drug Metab Rev
, vol.31
, pp. 649-663
-
-
Gold, B.G.1
-
24
-
-
17744386191
-
Non-FK506-binding protein-12 neuroimmunophilin ligands increase neurite elongation and accelerate nerve regeneration
-
Gold B.G., Armistead D.M., Wang M.S. Non-FK506-binding protein-12 neuroimmunophilin ligands increase neurite elongation and accelerate nerve regeneration. J Neurosci Res 2005, 80:56-65.
-
(2005)
J Neurosci Res
, vol.80
, pp. 56-65
-
-
Gold, B.G.1
Armistead, D.M.2
Wang, M.S.3
-
25
-
-
0033034203
-
Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506
-
Gold B.G., Densmore V., Shou W., Matzuk M.M., Gordon H.S. Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506. J Pharmacol Exp Ther 1999, 289:1202-1210.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 1202-1210
-
-
Gold, B.G.1
Densmore, V.2
Shou, W.3
Matzuk, M.M.4
Gordon, H.S.5
-
26
-
-
0028783373
-
The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve
-
Gold B.G., Katoh K., Storm-Dickerson T. The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve. J Neurosci 1995, 15:7509-7516.
-
(1995)
J Neurosci
, vol.15
, pp. 7509-7516
-
-
Gold, B.G.1
Katoh, K.2
Storm-Dickerson, T.3
-
27
-
-
0032559196
-
The immunosuppressant FK506 increases GAP-43 mRNA levels in axotomized sensory neurons
-
Gold B.G., Yew J.Y., Zeleny-Pooley M. The immunosuppressant FK506 increases GAP-43 mRNA levels in axotomized sensory neurons. Neurosci Lett 1998, 241:25-28.
-
(1998)
Neurosci Lett
, vol.241
, pp. 25-28
-
-
Gold, B.G.1
Yew, J.Y.2
Zeleny-Pooley, M.3
-
28
-
-
1842507643
-
FK506 requires stimulation of the extracellular signal-regulated kinase 1/2 and the steroid receptor chaperone protein p23 for neurite elongation
-
Gold B.G., Zhong Y.P. FK506 requires stimulation of the extracellular signal-regulated kinase 1/2 and the steroid receptor chaperone protein p23 for neurite elongation. Neurosignals 2004, 13:122-129.
-
(2004)
Neurosignals
, vol.13
, pp. 122-129
-
-
Gold, B.G.1
Zhong, Y.P.2
-
29
-
-
0030640846
-
Long-term response to nerve injury
-
Gordon T., Fu S.Y. Long-term response to nerve injury. Adv Neurol 1997, 72:185-199.
-
(1997)
Adv Neurol
, vol.72
, pp. 185-199
-
-
Gordon, T.1
Fu, S.Y.2
-
30
-
-
0023639234
-
Discovery of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis
-
Goto T., Kino T., Hatanaka H., Nishiyama M., Okuhara M., Kohsaka M., Aoki H., Imanaka H. Discovery of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. Transplant Proc 1987, 19:4-8.
-
(1987)
Transplant Proc
, vol.19
, pp. 4-8
-
-
Goto, T.1
Kino, T.2
Hatanaka, H.3
Nishiyama, M.4
Okuhara, M.5
Kohsaka, M.6
Aoki, H.7
Imanaka, H.8
-
31
-
-
0036237963
-
Axonal regeneration after cold preservation of nerve allografts and immunosuppression with tacrolimus in mice
-
Grand A.G., Myckatyn T.M., Mackinnon S.E., Hunter D.A. Axonal regeneration after cold preservation of nerve allografts and immunosuppression with tacrolimus in mice. J Neurosurg 2002, 96:924-932.
-
(2002)
J Neurosurg
, vol.96
, pp. 924-932
-
-
Grand, A.G.1
Myckatyn, T.M.2
Mackinnon, S.E.3
Hunter, D.A.4
-
32
-
-
0002496352
-
The re-innervation of muscle after various periods of atrophy
-
Gutmann E., Young J.Z. The re-innervation of muscle after various periods of atrophy. J Anat 1944, 78:15-43.
-
(1944)
J Anat
, vol.78
, pp. 15-43
-
-
Gutmann, E.1
Young, J.Z.2
-
33
-
-
0026529122
-
Walking track analysis: a long-term assessment of peripheral nerve recovery
-
Hare G.M., Evans P.J., Mackinnon S.E., Best T.J., Bain J.R., Szalai J.P., Hunter D.A. Walking track analysis: a long-term assessment of peripheral nerve recovery. Plast Reconstr Surg 1992, 89:251-258.
-
(1992)
Plast Reconstr Surg
, vol.89
, pp. 251-258
-
-
Hare, G.M.1
Evans, P.J.2
Mackinnon, S.E.3
Best, T.J.4
Bain, J.R.5
Szalai, J.P.6
Hunter, D.A.7
-
34
-
-
0027403758
-
Walking track analysis: utilization of individual footprint parameters
-
Hare G.M., Evans P.J., Mackinnon S.E., Best T.J., Midha R., Szalai J.P., Hunter D.A. Walking track analysis: utilization of individual footprint parameters. Ann Plast Surg 1993, 30:147-153.
-
(1993)
Ann Plast Surg
, vol.30
, pp. 147-153
-
-
Hare, G.M.1
Evans, P.J.2
Mackinnon, S.E.3
Best, T.J.4
Midha, R.5
Szalai, J.P.6
Hunter, D.A.7
-
35
-
-
43449111177
-
Axotomy or compression is required for axonal sprouting following end-to-side neurorrhaphy
-
Hayashi A., Pannucci C., Moradzadeh A., Kawamura D., Magill C., Hunter D.A., Tong A.Y., Parsadanian A., Mackinnon S.E., Myckatyn T.M. Axotomy or compression is required for axonal sprouting following end-to-side neurorrhaphy. Exp Neurol 2008, 211:539-550.
-
(2008)
Exp Neurol
, vol.211
, pp. 539-550
-
-
Hayashi, A.1
Pannucci, C.2
Moradzadeh, A.3
Kawamura, D.4
Magill, C.5
Hunter, D.A.6
Tong, A.Y.7
Parsadanian, A.8
Mackinnon, S.E.9
Myckatyn, T.M.10
-
36
-
-
34347258879
-
Small molecule inducers of heat-shock response reduce polyQ-mediated huntingtin aggregation. A possible therapeutic strategy
-
Herbst M., Wanker E.E. Small molecule inducers of heat-shock response reduce polyQ-mediated huntingtin aggregation. A possible therapeutic strategy. Neurodegener Dis 2007, 4:254-260.
-
(2007)
Neurodegener Dis
, vol.4
, pp. 254-260
-
-
Herbst, M.1
Wanker, E.E.2
-
37
-
-
0036144945
-
A decline in glial cell-line-derived neurotrophic factor expression is associated with impaired regeneration after long-term Schwann cell denervation
-
Hoke A., Gordon T., Zochodne D.W., Sulaiman O.A. A decline in glial cell-line-derived neurotrophic factor expression is associated with impaired regeneration after long-term Schwann cell denervation. Exp Neurol 2002, 173:77-85.
-
(2002)
Exp Neurol
, vol.173
, pp. 77-85
-
-
Hoke, A.1
Gordon, T.2
Zochodne, D.W.3
Sulaiman, O.A.4
-
38
-
-
0036294772
-
Skeletal muscle denervation increases satellite cell susceptibility to apoptosis
-
Jejurikar S.S., Marcelo C.L., Kuzon W.M. Skeletal muscle denervation increases satellite cell susceptibility to apoptosis. Plast Reconstr Surg 2002, 110:160-168.
-
(2002)
Plast Reconstr Surg
, vol.110
, pp. 160-168
-
-
Jejurikar, S.S.1
Marcelo, C.L.2
Kuzon, W.M.3
-
39
-
-
15944382683
-
Effect of FK506 on peripheral nerve regeneration through long grafts in inbred swine
-
Jensen J.N., Brenner M.J., Tung T.H., Hunter D.A., Mackinnon S.E. Effect of FK506 on peripheral nerve regeneration through long grafts in inbred swine. Ann Plast Surg 2005, 54:420-427.
-
(2005)
Ann Plast Surg
, vol.54
, pp. 420-427
-
-
Jensen, J.N.1
Brenner, M.J.2
Tung, T.H.3
Hunter, D.A.4
Mackinnon, S.E.5
-
40
-
-
58749097968
-
Neurite outgrowth of NG108-15 cells induced by heat shock protein 90 inhibitors
-
Jin E., Sano M. Neurite outgrowth of NG108-15 cells induced by heat shock protein 90 inhibitors. Cell Biochem Funct 2008, 26:825-832.
-
(2008)
Cell Biochem Funct
, vol.26
, pp. 825-832
-
-
Jin, E.1
Sano, M.2
-
41
-
-
0033755467
-
Acceleration of peripheral nerve regeneration following FK506 administration
-
Jost S.C., Doolabh V.B., Mackinnon S.E., Lee M., Hunter D. Acceleration of peripheral nerve regeneration following FK506 administration. Restor Neurol Neurosci 2000, 17:39-44.
-
(2000)
Restor Neurol Neurosci
, vol.17
, pp. 39-44
-
-
Jost, S.C.1
Doolabh, V.B.2
Mackinnon, S.E.3
Lee, M.4
Hunter, D.5
-
42
-
-
59849123078
-
Calcineurin negatively regulates TLR-mediated activation pathways
-
Kang Y.J., Kusler B., Otsuka M., Hughes M., Suzuki N., Suzuki S., Yeh W.C., Akira S., Han J., Jones P.P. Calcineurin negatively regulates TLR-mediated activation pathways. J Immunol 2007, 179:4598-4607.
-
(2007)
J Immunol
, vol.179
, pp. 4598-4607
-
-
Kang, Y.J.1
Kusler, B.2
Otsuka, M.3
Hughes, M.4
Suzuki, N.5
Suzuki, S.6
Yeh, W.C.7
Akira, S.8
Han, J.9
Jones, P.P.10
-
43
-
-
0023245677
-
FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics
-
Kino T., Hatanaka H., Hashimoto M., Nishiyama M., Goto T., Okuhara M., Kohsaka M., Aoki H., Imanaka H. FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot (Tokyo) 1987, 40:1249-1255.
-
(1987)
J Antibiot (Tokyo)
, vol.40
, pp. 1249-1255
-
-
Kino, T.1
Hatanaka, H.2
Hashimoto, M.3
Nishiyama, M.4
Goto, T.5
Okuhara, M.6
Kohsaka, M.7
Aoki, H.8
Imanaka, H.9
-
44
-
-
0023261356
-
FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro
-
Kino T., Hatanaka H., Miyata S., Inamura N., Nishiyama M., Yajima T., Goto T., Okuhara M., Kohsaka M., Aoki H., et al. FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J Antibiot (Tokyo) 1987, 40:1256-1265.
-
(1987)
J Antibiot (Tokyo)
, vol.40
, pp. 1256-1265
-
-
Kino, T.1
Hatanaka, H.2
Miyata, S.3
Inamura, N.4
Nishiyama, M.5
Yajima, T.6
Goto, T.7
Okuhara, M.8
Kohsaka, M.9
Aoki, H.10
-
45
-
-
0030950903
-
The effect of duration of muscle denervation on functional recovery in the rat model
-
Kobayashi J., Mackinnon S.E., Watanabe O., Ball D.J., Gu X.M., Hunter D.A., Kuzon W.M. The effect of duration of muscle denervation on functional recovery in the rat model. Muscle Nerve 1997, 20:858-866.
-
(1997)
Muscle Nerve
, vol.20
, pp. 858-866
-
-
Kobayashi, J.1
Mackinnon, S.E.2
Watanabe, O.3
Ball, D.J.4
Gu, X.M.5
Hunter, D.A.6
Kuzon, W.M.7
-
46
-
-
51649109912
-
Geldanamycin protects rat brain through overexpression of HSP70 and reducing brain edema after cerebral focal ischemia
-
Kwon H.M., Kim Y., Yang S.I., Kim Y.J., Lee S.H., Yoon B.W. Geldanamycin protects rat brain through overexpression of HSP70 and reducing brain edema after cerebral focal ischemia. Neurol Res 2008, 30:740-745.
-
(2008)
Neurol Res
, vol.30
, pp. 740-745
-
-
Kwon, H.M.1
Kim, Y.2
Yang, S.I.3
Kim, Y.J.4
Lee, S.H.5
Yoon, B.W.6
-
47
-
-
67650151770
-
Differential expression of HSP70 mRNA in the mouse brain after treatment with geldanamycin
-
Kwon H.M., Kim Y.J., Ryu S., Yang S.I., Lee S.H., Yoon B.W. Differential expression of HSP70 mRNA in the mouse brain after treatment with geldanamycin. Neurol Res 2009, 31:541-544.
-
(2009)
Neurol Res
, vol.31
, pp. 541-544
-
-
Kwon, H.M.1
Kim, Y.J.2
Ryu, S.3
Yang, S.I.4
Lee, S.H.5
Yoon, B.W.6
-
48
-
-
0032472832
-
Mechanisms of enhancement of neurite regeneration in vitro following a conditioning sciatic nerve lesion
-
Lankford K.L., Waxman S.G., Kocsis J.D. Mechanisms of enhancement of neurite regeneration in vitro following a conditioning sciatic nerve lesion. J Comp Neurol 1998, 391:11-29.
-
(1998)
J Comp Neurol
, vol.391
, pp. 11-29
-
-
Lankford, K.L.1
Waxman, S.G.2
Kocsis, J.D.3
-
49
-
-
0034022271
-
FK506 promotes functional recovery in crushed rat sciatic nerve
-
Lee M., Doolabh V.B., Mackinnon S.E., Jost S. FK506 promotes functional recovery in crushed rat sciatic nerve. Muscle Nerve 2000, 23:633-640.
-
(2000)
Muscle Nerve
, vol.23
, pp. 633-640
-
-
Lee, M.1
Doolabh, V.B.2
Mackinnon, S.E.3
Jost, S.4
-
50
-
-
0033152937
-
Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90
-
Lele Z., Hartson S.D., Martin C.C., Whitesell L., Matts R.L., Krone P.H. Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90. Dev Biol 1999, 210:56-70.
-
(1999)
Dev Biol
, vol.210
, pp. 56-70
-
-
Lele, Z.1
Hartson, S.D.2
Martin, C.C.3
Whitesell, L.4
Matts, R.L.5
Krone, P.H.6
-
51
-
-
0035830777
-
Opposite effects of the Hsp90 inhibitor geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells
-
Lopez-Maderuelo M.D., Fernandez-Renart M., Moratilla C., Renart J. Opposite effects of the Hsp90 inhibitor geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells. FEBS Lett 2001, 490:23-27.
-
(2001)
FEBS Lett
, vol.490
, pp. 23-27
-
-
Lopez-Maderuelo, M.D.1
Fernandez-Renart, M.2
Moratilla, C.3
Renart, J.4
-
52
-
-
27444436221
-
FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat
-
Lopez-Vales R., Garcia-Alias G., Fores J., Udina E., Gold B.G., Navarro X., Verdu E. FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat. J Neurosci Res 2005, 81:827-836.
-
(2005)
J Neurosci Res
, vol.81
, pp. 827-836
-
-
Lopez-Vales, R.1
Garcia-Alias, G.2
Fores, J.3
Udina, E.4
Gold, B.G.5
Navarro, X.6
Verdu, E.7
-
53
-
-
0035035481
-
Clinical outcome following nerve allograft transplantation
-
Mackinnon S.E., Doolabh V.B., Novak C.B., Trulock E.P. Clinical outcome following nerve allograft transplantation. Plast Reconstr Surg 2001, 107:1419-1429.
-
(2001)
Plast Reconstr Surg
, vol.107
, pp. 1419-1429
-
-
Mackinnon, S.E.1
Doolabh, V.B.2
Novak, C.B.3
Trulock, E.P.4
-
54
-
-
0032411557
-
Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats
-
Madsen J.R., MacDonald P., Irwin N., Goldberg D.E., Yao G.L., Meiri K.F., Rimm I.J., Stieg P.E., Benowitz L.I. Tacrolimus (FK506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats. Exp Neurol 1998, 154:673-683.
-
(1998)
Exp Neurol
, vol.154
, pp. 673-683
-
-
Madsen, J.R.1
MacDonald, P.2
Irwin, N.3
Goldberg, D.E.4
Yao, G.L.5
Meiri, K.F.6
Rimm, I.J.7
Stieg, P.E.8
Benowitz, L.I.9
-
55
-
-
77958100218
-
Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage
-
Manaenko A., Fathali N., Chen H., Suzuki H., Williams S., Zhang J.H., Tang J. Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage. Neurochem Int 2010, 57:844-850.
-
(2010)
Neurochem Int
, vol.57
, pp. 844-850
-
-
Manaenko, A.1
Fathali, N.2
Chen, H.3
Suzuki, H.4
Williams, S.5
Zhang, J.H.6
Tang, J.7
-
56
-
-
4344569643
-
Geldanamycin induces Hsp70 and prevents alpha-synuclein aggregation and toxicity in vitro
-
McLean P.J., Klucken J., Shin Y., Hyman B.T. Geldanamycin induces Hsp70 and prevents alpha-synuclein aggregation and toxicity in vitro. Biochem Biophys Res Commun 2004, 321:665-669.
-
(2004)
Biochem Biophys Res Commun
, vol.321
, pp. 665-669
-
-
McLean, P.J.1
Klucken, J.2
Shin, Y.3
Hyman, B.T.4
-
57
-
-
0018237730
-
The effect of a conditioning lesion on the regeneration of motor axons
-
McQuarrie I.G. The effect of a conditioning lesion on the regeneration of motor axons. Brain Res 1978, 152:597-602.
-
(1978)
Brain Res
, vol.152
, pp. 597-602
-
-
McQuarrie, I.G.1
-
58
-
-
0029812759
-
Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin
-
Mimnaugh E.G., Chavany C., Neckers L. Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin. J Biol Chem 1996, 271:22796-22801.
-
(1996)
J Biol Chem
, vol.271
, pp. 22796-22801
-
-
Mimnaugh, E.G.1
Chavany, C.2
Neckers, L.3
-
59
-
-
15544385359
-
Hsp90 inhibitor geldanamycin and its derivatives as novel cancer chemotherapeutic agents
-
Miyata Y. Hsp90 inhibitor geldanamycin and its derivatives as novel cancer chemotherapeutic agents. Curr Pharm Des 2005, 11:1131-1138.
-
(2005)
Curr Pharm Des
, vol.11
, pp. 1131-1138
-
-
Miyata, Y.1
-
60
-
-
82055194414
-
A transgenic rat expressing green fluorescent protein (GFP) in peripheral nerves provides a new hindlimb model for the study of nerve injury and regeneration
-
Moore A.M., Borschel G.H., Santosa K.A., Flagg E.R., Tong A.Y., Kasukurthi R., Newton P., Yan Y., Hunter D.A., Johnson P.J., Mackinnon S.E. A transgenic rat expressing green fluorescent protein (GFP) in peripheral nerves provides a new hindlimb model for the study of nerve injury and regeneration. J Neurosci Methods 2011, 204:19-27.
-
(2011)
J Neurosci Methods
, vol.204
, pp. 19-27
-
-
Moore, A.M.1
Borschel, G.H.2
Santosa, K.A.3
Flagg, E.R.4
Tong, A.Y.5
Kasukurthi, R.6
Newton, P.7
Yan, Y.8
Hunter, D.A.9
Johnson, P.J.10
Mackinnon, S.E.11
-
61
-
-
79960516209
-
Acellular nerve allografts in peripheral nerve regeneration: a comparative study
-
Moore A.M., MacEwan M., Santosa K.B., Chenard K.E., Ray W.Z., Hunter D.A., Mackinnon S.E., Johnson P.J. Acellular nerve allografts in peripheral nerve regeneration: a comparative study. Muscle Nerve 2011, 44:221-234.
-
(2011)
Muscle Nerve
, vol.44
, pp. 221-234
-
-
Moore, A.M.1
MacEwan, M.2
Santosa, K.B.3
Chenard, K.E.4
Ray, W.Z.5
Hunter, D.A.6
Mackinnon, S.E.7
Johnson, P.J.8
-
62
-
-
0036114008
-
The effects of rapamycin in murine peripheral nerve isografts and allografts
-
Myckatyn T.M., Ellis R.A., Grand A.G., Sen S.K., Lowe J.B., Hunter D.A., Mackinnon S.E. The effects of rapamycin in murine peripheral nerve isografts and allografts. Plast Reconstr Surg 2002, 109:2405-2417.
-
(2002)
Plast Reconstr Surg
, vol.109
, pp. 2405-2417
-
-
Myckatyn, T.M.1
Ellis, R.A.2
Grand, A.G.3
Sen, S.K.4
Lowe, J.B.5
Hunter, D.A.6
Mackinnon, S.E.7
-
63
-
-
0034975002
-
Effects of FK506 on nerve regeneration and reinnervation after graft or tube repair of long nerve gaps
-
Navarro X., Udina E., Ceballos D., Gold B.G. Effects of FK506 on nerve regeneration and reinnervation after graft or tube repair of long nerve gaps. Muscle Nerve 2001, 24:905-915.
-
(2001)
Muscle Nerve
, vol.24
, pp. 905-915
-
-
Navarro, X.1
Udina, E.2
Ceballos, D.3
Gold, B.G.4
-
64
-
-
0033829374
-
An introduction to the changes in gene expression that occur after cerebral ischaemia
-
Papadopoulos M.C., Giffard R.G., Bell B.A. An introduction to the changes in gene expression that occur after cerebral ischaemia. Br J Neurosurg 2000, 14:305-312.
-
(2000)
Br J Neurosurg
, vol.14
, pp. 305-312
-
-
Papadopoulos, M.C.1
Giffard, R.G.2
Bell, B.A.3
-
65
-
-
48849117470
-
Total synthesis of the Hsp90 inhibitor geldanamycin
-
Qin H.L., Panek J.S. Total synthesis of the Hsp90 inhibitor geldanamycin. Org Lett 2008, 10:2477-2479.
-
(2008)
Org Lett
, vol.10
, pp. 2477-2479
-
-
Qin, H.L.1
Panek, J.S.2
-
66
-
-
0028818456
-
Satellite cells and myonuclei in long-term denervated rat muscles
-
Rodrigues Ade C., Schmalbruch H. Satellite cells and myonuclei in long-term denervated rat muscles. Anat Rec 1995, 243:430-437.
-
(1995)
Anat Rec
, vol.243
, pp. 430-437
-
-
Rodrigues Ade, C.1
Schmalbruch, H.2
-
67
-
-
0023925825
-
Long-term endoneurial changes after nerve transection
-
Roytta M., Salonen V. Long-term endoneurial changes after nerve transection. Acta Neuropathol 1988, 76:35-45.
-
(1988)
Acta Neuropathol
, vol.76
, pp. 35-45
-
-
Roytta, M.1
Salonen, V.2
-
68
-
-
0028278119
-
A comparison of the morphology of denervated with aneurally regenerated soleus muscle of rat
-
Schmalbruch H., Lewis D.M. A comparison of the morphology of denervated with aneurally regenerated soleus muscle of rat. J Muscle Res Cell Motil 1994, 15:256-266.
-
(1994)
J Muscle Res Cell Motil
, vol.15
, pp. 256-266
-
-
Schmalbruch, H.1
Lewis, D.M.2
-
69
-
-
0025012023
-
Effects of repetitive conditioning crush lesions on regeneration of the rat sciatic nerve
-
Sjoberg J., Kanje M. Effects of repetitive conditioning crush lesions on regeneration of the rat sciatic nerve. Brain Res 1990, 530:167-169.
-
(1990)
Brain Res
, vol.530
, pp. 167-169
-
-
Sjoberg, J.1
Kanje, M.2
-
70
-
-
33746683259
-
Neuroregenerative effects of preinjury FK-506 administration
-
Snyder A.K., Fox I.K., Nichols C.M., Rickman S.R., Hunter D.A., Tung T.H., Mackinnon S.E. Neuroregenerative effects of preinjury FK-506 administration. Plast Reconstr Surg 2006, 118:360-367.
-
(2006)
Plast Reconstr Surg
, vol.118
, pp. 360-367
-
-
Snyder, A.K.1
Fox, I.K.2
Nichols, C.M.3
Rickman, S.R.4
Hunter, D.A.5
Tung, T.H.6
Mackinnon, S.E.7
-
71
-
-
0037304205
-
Effects of delaying FK506 administration on neuroregeneration in a rodent model
-
Sobol J.B., Lowe I.J., Yang R.K., Sen S.K., Hunter D.A., Mackinnon S.E. Effects of delaying FK506 administration on neuroregeneration in a rodent model. J Reconstr Microsurg 2003, 19:113-118.
-
(2003)
J Reconstr Microsurg
, vol.19
, pp. 113-118
-
-
Sobol, J.B.1
Lowe, I.J.2
Yang, R.K.3
Sen, S.K.4
Hunter, D.A.5
Mackinnon, S.E.6
-
72
-
-
0031005361
-
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent
-
Stebbins C.E., Russo A.A., Schneider C., Rosen N., Hartl F.U., Pavletich N.P. Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell 1997, 89:239-250.
-
(1997)
Cell
, vol.89
, pp. 239-250
-
-
Stebbins, C.E.1
Russo, A.A.2
Schneider, C.3
Rosen, N.4
Hartl, F.U.5
Pavletich, N.P.6
-
73
-
-
0029056501
-
Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent
-
Supko J.G., Hickman R.L., Grever M.R., Malspeis L. Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent. Cancer Chemother Pharmacol 1995, 36:305-315.
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 305-315
-
-
Supko, J.G.1
Hickman, R.L.2
Grever, M.R.3
Malspeis, L.4
-
74
-
-
34247373120
-
Geldanamycin derivatives and neuroprotective effect on cultured P19-derived neurons
-
Tadtong S., Meksuriyen D., Tanasupawat S., Isobe M., Suwanborirux K. Geldanamycin derivatives and neuroprotective effect on cultured P19-derived neurons. Bioorg Med Chem Lett 2007, 17:2939-2943.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 2939-2943
-
-
Tadtong, S.1
Meksuriyen, D.2
Tanasupawat, S.3
Isobe, M.4
Suwanborirux, K.5
-
75
-
-
2642539336
-
Comparison of continuous and discontinuous FK506 administration on autograft or allograft repair of sciatic nerve resection
-
Udina E., Gold B.G., Navarro X. Comparison of continuous and discontinuous FK506 administration on autograft or allograft repair of sciatic nerve resection. Muscle Nerve 2004, 29:812-822.
-
(2004)
Muscle Nerve
, vol.29
, pp. 812-822
-
-
Udina, E.1
Gold, B.G.2
Navarro, X.3
-
76
-
-
0042191634
-
Comparative dose-dependence study of FK506 on transected mouse sciatic nerve repaired by allograft or xenograft
-
Udina E., Voda J., Gold B.G., Navarro X. Comparative dose-dependence study of FK506 on transected mouse sciatic nerve repaired by allograft or xenograft. J Peripher Nerv Syst 2003, 8:145-154.
-
(2003)
J Peripher Nerv Syst
, vol.8
, pp. 145-154
-
-
Udina, E.1
Voda, J.2
Gold, B.G.3
Navarro, X.4
-
77
-
-
0030995702
-
Quantitative study of the effects of long-term denervation on the extensor digitorum longus muscle of the rat
-
Viguie C.A., Lu D.X., Huang S.K., Rengen H., Carlson B.M. Quantitative study of the effects of long-term denervation on the extensor digitorum longus muscle of the rat. Anat Rec 1997, 248:346-354.
-
(1997)
Anat Rec
, vol.248
, pp. 346-354
-
-
Viguie, C.A.1
Lu, D.X.2
Huang, S.K.3
Rengen, H.4
Carlson, B.M.5
-
78
-
-
0033289087
-
FK506 increases the regeneration of spinal cord axons in a predegenerated peripheral nerve autograft
-
Wang M.S., Gold B.G. FK506 increases the regeneration of spinal cord axons in a predegenerated peripheral nerve autograft. J Spinal Cord Med 1999, 22:287-296.
-
(1999)
J Spinal Cord Med
, vol.22
, pp. 287-296
-
-
Wang, M.S.1
Gold, B.G.2
-
79
-
-
0029973294
-
Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells
-
Whitesell L., Cook P. Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. Mol Endocrinol 1996, 10:705-712.
-
(1996)
Mol Endocrinol
, vol.10
, pp. 705-712
-
-
Whitesell, L.1
Cook, P.2
-
80
-
-
84863710333
-
Efficacy of Short-Term FK506 Administration on Accelerating Nerve Regeneration
-
Yan Y., Sun H.H., Hunter D.A., Mackinnon S.E., Johnson P.J. Efficacy of Short-Term FK506 Administration on Accelerating Nerve Regeneration. Neurorehabil Neural Repair 2012, 26:570-580.
-
(2012)
Neurorehabil Neural Repair
, vol.26
, pp. 570-580
-
-
Yan, Y.1
Sun, H.H.2
Hunter, D.A.3
Mackinnon, S.E.4
Johnson, P.J.5
-
81
-
-
80053955733
-
Evaluation of peripheral nerve regeneration via in vivo serial transcutaneous imaging using transgenic Thy1-YFP mice
-
Yan Y., Sun H.H., Mackinnon S.E., Johnson P.J. Evaluation of peripheral nerve regeneration via in vivo serial transcutaneous imaging using transgenic Thy1-YFP mice. Exp Neurol 2011, 232:7-14.
-
(2011)
Exp Neurol
, vol.232
, pp. 7-14
-
-
Yan, Y.1
Sun, H.H.2
Mackinnon, S.E.3
Johnson, P.J.4
-
82
-
-
0642333766
-
Dose-dependent effects of FK506 on neuroregeneration in a rat model
-
Yang R.K., Lowe J.B., Sobol J.B., Sen S.K., Hunter D.A., Mackinnon S.E. Dose-dependent effects of FK506 on neuroregeneration in a rat model. Plast Reconstr Surg 2003, 112:1832-1840.
-
(2003)
Plast Reconstr Surg
, vol.112
, pp. 1832-1840
-
-
Yang, R.K.1
Lowe, J.B.2
Sobol, J.B.3
Sen, S.K.4
Hunter, D.A.5
Mackinnon, S.E.6
-
83
-
-
0037784052
-
Geldanamycin inhibits migration of glioma cells in vitro: a potential role for hypoxia-inducible factor (HIF-1alpha) in glioma cell invasion
-
Zagzag D., Nomura M., Friedlander D.R., Blanco C.Y., Gagner J.P., Nomura N., Newcomb E.W. Geldanamycin inhibits migration of glioma cells in vitro: a potential role for hypoxia-inducible factor (HIF-1alpha) in glioma cell invasion. J Cell Physiol 2003, 196:394-402.
-
(2003)
J Cell Physiol
, vol.196
, pp. 394-402
-
-
Zagzag, D.1
Nomura, M.2
Friedlander, D.R.3
Blanco, C.Y.4
Gagner, J.P.5
Nomura, N.6
Newcomb, E.W.7
|