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Volumn 31, Issue 3, 1999, Pages 649-663

FK506 and the role of the immunophilin FKBP-52 in nerve regeneration

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; DEXAMETHASONE; ESTRADIOL; ESTROGEN RECEPTOR; FK 506 BINDING PROTEIN; GELDANAMYCIN; GLUCOCORTICOID RECEPTOR; IMMUNOPHILIN; IMMUNOSUPPRESSIVE AGENT; MOLYBDIC ACID; MONOCLONAL ANTIBODY; STEROID HORMONE; TACROLIMUS;

EID: 0032776433     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.1081/DMR-100101940     Document Type: Conference Paper
Times cited : (83)

References (75)
  • 1
    • 0031309575 scopus 로고    scopus 로고
    • FK506 and the role of immunophilins in nerve regeneration
    • B. G. Gold, FK506 and the role of immunophilins in nerve regeneration, Mol. Neurobiol., 15, 285-306 (1997).
    • (1997) Mol. Neurobiol. , vol.15 , pp. 285-306
    • Gold, B.G.1
  • 2
    • 0023245677 scopus 로고
    • FK-506, a novel immunosuppressant isolated from a streptomyces. I. Fermentation, isolation, and physio-chemical and biological characteristics
    • T. Kino, H. Hatanaka, M. Hashimoto, and H. Nishiyama, FK-506, a novel immunosuppressant isolated from a streptomyces. I. Fermentation, isolation, and physio-chemical and biological characteristics, J. Antibiot., 40, 1249-1255 (1987).
    • (1987) J. Antibiot. , vol.40 , pp. 1249-1255
    • Kino, T.1    Hatanaka, H.2    Hashimoto, M.3    Nishiyama, H.4
  • 4
    • 0025270425 scopus 로고
    • The use of FK-506 for small intestine allotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease
    • A. L. Hoffman, L. Makowka, B. Banner, X. Cai, D. V. Cramer, A. Pascualone, S. Todo, and T. E. Starzl, The use of FK-506 for small intestine allotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease, Transplantation, 49, 483-490 (1990).
    • (1990) Transplantation , vol.49 , pp. 483-490
    • Hoffman, A.L.1    Makowka, L.2    Banner, B.3    Cai, X.4    Cramer, D.V.5    Pascualone, A.6    Todo, S.7    Starzl, T.E.8
  • 5
    • 0002740007 scopus 로고
    • FK-506: A potential breakthrough in immunosuppression
    • T. E. Starzl, L. Makowka, and S. Todo, FK-506: A potential breakthrough in immunosuppression, Transplant. Proc., 19, S3-S104 (1987).
    • (1987) Transplant. Proc. , vol.19
    • Starzl, T.E.1    Makowka, L.2    Todo, S.3
  • 7
    • 0027220342 scopus 로고
    • Discovery of FK-506 and update
    • T. Kino and T. Goto, Discovery of FK-506 and update, Ann. NY Acad. Sci. 685, 13-21 (1993).
    • (1993) Ann. NY Acad. Sci. , vol.685 , pp. 13-21
    • Kino, T.1    Goto, T.2
  • 10
    • 0026575932 scopus 로고
    • The mechanism of action of cyclosporin A and FK506
    • S. L. Schreiber and G. R. Crabtree, The mechanism of action of cyclosporin A and FK506, Immunol. Today, 13, 136-142 (1992).
    • (1992) Immunol. Today , vol.13 , pp. 136-142
    • Schreiber, S.L.1    Crabtree, G.R.2
  • 11
    • 0026030568 scopus 로고
    • Chemistry and biology of the immunophilins and their immunosuppressive ligands
    • S. L. Schreiber, Chemistry and biology of the immunophilins and their immunosuppressive ligands, Science, 251, 283-287 (1991).
    • (1991) Science , vol.251 , pp. 283-287
    • Schreiber, S.L.1
  • 12
    • 0027184498 scopus 로고
    • Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein
    • E. S. Alnemri, T. Fernandes-Alnemri, D. S. Nelki, K. Dudley, G. C. DuBois, and G. Litwack, Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein, Proc. Natl. Acad. Sci. USA, 90, 6839-6843 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6839-6843
    • Alnemri, E.S.1    Fernandes-Alnemri, T.2    Nelki, D.S.3    Dudley, K.4    DuBois, G.C.5    Litwack, G.6
  • 13
    • 0026748870 scopus 로고
    • Cyclosporin A, FK-506, and Rapamycin: Pharmacologic probes of lymphocyte signal transduction
    • N. H. Sigal and F. J. Dumont, Cyclosporin A, FK-506, and Rapamycin: Pharmacologic probes of lymphocyte signal transduction, Annu. Rev. Immunol., 10, 519-560 (1992).
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 519-560
    • Sigal, N.H.1    Dumont, F.J.2
  • 14
    • 0026503434 scopus 로고
    • Calcineurin phosphatase activity in T lymphocytes is inhibited by FK506 and cyclosporin A
    • D. A. Freman, C. B. Klee, B. E. Bierer, and S. J. Burakoff, Calcineurin phosphatase activity in T lymphocytes is inhibited by FK506 and cyclosporin A, Proc. Natl. Acad. Sci. USA, 89, 3686-3690 (1992).
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3686-3690
    • Freman, D.A.1    Klee, C.B.2    Bierer, B.E.3    Burakoff, S.J.4
  • 15
    • 0019519075 scopus 로고
    • Permanent axotomy, a model of axonal atrophy and secondary segmental demyelination and remyelination
    • P. J. Dyck, A. C. Lais, J. L. Karnes, M. Sparks, H. Hunter, and P. A. Low, Permanent axotomy, a model of axonal atrophy and secondary segmental demyelination and remyelination, Ann. Neurol., 19, 575-583 (1981).
    • (1981) Ann. Neurol. , vol.19 , pp. 575-583
    • Dyck, P.J.1    Lais, A.C.2    Karnes, J.L.3    Sparks, M.4    Hunter, H.5    Low, P.A.6
  • 16
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • J. Liu, J. D. Farmer, W. S. Lane, J. Friedman, I. Weissman, and S. L. Schreiber, Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes, Cell, 66, 807-815 (1991).
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 17
    • 0026629246 scopus 로고
    • Cyclosporin A, the cyclophilin class of peptidylprolyl isomerases, and blockade of T cell signal transduction
    • C. T. Walsh, L. D. Zydowsky, and F. D. McKeon, Cyclosporin A, the cyclophilin class of peptidylprolyl isomerases, and blockade of T cell signal transduction, J. Biol. Chem., 267, 13,115-13,118 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 13115-13118
    • Walsh, C.T.1    Zydowsky, L.D.2    McKeon, F.D.3
  • 18
    • 0026744641 scopus 로고
    • Transcription of IL-4 genes is not inhibited by cyclosporin A in competent T cells
    • N. Terada, R. Or, K. Weinberg, J. Domenico, J. J. Lucas, and E. W. Gelfand, Transcription of IL-4 genes is not inhibited by cyclosporin A in competent T cells, J. Biol. Chem., 267, 21,207-21,210 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 21207-21210
    • Terada, N.1    Or, R.2    Weinberg, K.3    Domenico, J.4    Lucas, J.J.5    Gelfand, E.W.6
  • 21
    • 0028956418 scopus 로고
    • Neuronal regeneration enhances the expression of the immunophilin FKBP-12
    • W. E. Lyons, J. P. Steiner, S. H. Snyder, and T. M. Dawson, Neuronal regeneration enhances the expression of the immunophilin FKBP-12, J. Neurosci., 15, 2985-2994 (1995).
    • (1995) J. Neurosci. , vol.15 , pp. 2985-2994
    • Lyons, W.E.1    Steiner, J.P.2    Snyder, S.H.3    Dawson, T.M.4
  • 22
    • 2542509071 scopus 로고    scopus 로고
    • Immunophilins, heat shock protein, and glucocorticoid receptor actions in vivo
    • E. R. Sánchez and Y.-M. Ning, Immunophilins, heat shock protein, and glucocorticoid receptor actions in vivo, Methods Enzymol., 9, 188-200 (1996).
    • (1996) Methods Enzymol. , vol.9 , pp. 188-200
    • Sánchez, E.R.1    Ning, Y.-M.2
  • 23
    • 0028900536 scopus 로고
    • Immunophilins and the nervous system
    • S. H. Snyder and D. M. Sabatini, Immunophilins and the nervous system, Nature Med., 1, 32-37 (1995).
    • (1995) Nature Med. , vol.1 , pp. 32-37
    • Snyder, S.H.1    Sabatini, D.M.2
  • 25
    • 0024472603 scopus 로고
    • A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase
    • M. W. Harding, A. Galat, D. E. Uehling, and S. L. Schreiber, A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase, Nature, 341, 758-760 (1989).
    • (1989) Nature , vol.341 , pp. 758-760
    • Harding, M.W.1    Galat, A.2    Uehling, D.E.3    Schreiber, S.L.4
  • 26
    • 0024442393 scopus 로고
    • A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin
    • J. J. Siekierka, S. H. Y. Hung, M. Poe, C. S. Lin, and N. H. Sigal, A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin, Nature, 341, 755-757 (1989).
    • (1989) Nature , vol.341 , pp. 755-757
    • Siekierka, J.J.1    Hung, S.H.Y.2    Poe, M.3    Lin, C.S.4    Sigal, N.H.5
  • 27
    • 0025635897 scopus 로고
    • The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase
    • J. J. Siekierka, G. Wiederrecht, H. Greulich, D. Boulton, S. H. Y. Hung, J. Cryan, P. J. Hodges, and N. H. Sigal, The cytosolic-binding protein for the immunosuppressant FK-506 is both a ubiquitous and highly conserved peptidyl-prolyl cis-trans isomerase, J. Biol. Chem., 265, 21,011-21,015 (1990).
    • (1990) J. Biol. Chem. , vol.265 , pp. 21011-21015
    • Siekierka, J.J.1    Wiederrecht, G.2    Greulich, H.3    Boulton, D.4    Hung, S.H.Y.5    Cryan, J.6    Hodges, P.J.7    Sigal, N.H.8
  • 28
    • 0009055643 scopus 로고
    • Increased expression of FK-506 binding protein during peripheral nerve regeneration
    • W. E. Lyons, J. P. Steiner, T. M. Dawson, and S. H. Snyder, Increased expression of FK-506 binding protein during peripheral nerve regeneration, Soc. Neurosci. Abstr., 18, 604 (1992).
    • (1992) Soc. Neurosci. Abstr. , vol.18 , pp. 604
    • Lyons, W.E.1    Steiner, J.P.2    Dawson, T.M.3    Snyder, S.H.4
  • 29
    • 0026076115 scopus 로고
    • Concerted regulation of protein phosphorylation and dephosphorylation by calmodulin
    • C. B. Klee, Concerted regulation of protein phosphorylation and dephosphorylation by calmodulin, Neurochem. Res., 16, 1059-1065 (1991).
    • (1991) Neurochem. Res. , vol.16 , pp. 1059-1065
    • Klee, C.B.1
  • 30
    • 0001084744 scopus 로고
    • FK506, an immunosuppressant, increases functional recovery and axonal regeneration in the rat following axotomy of the sciatic nerve
    • B. G. Gold, T. Storm-Dickerson, D. R. Austin, and K. Katoh, FK506, an immunosuppressant, increases functional recovery and axonal regeneration in the rat following axotomy of the sciatic nerve. Soc. Neurosci. Abstr., 19, 1316 (1993).
    • (1993) Soc. Neurosci. Abstr. , vol.19 , pp. 1316
    • Gold, B.G.1    Storm-Dickerson, T.2    Austin, D.R.3    Katoh, K.4
  • 31
    • 0028352763 scopus 로고
    • The immunosuppressant FK506 increases functional recovery and nerve regeneration following peripheral nerve injury
    • B. G. Gold, T. Storm-Dickerson, and D. R. Austin, The immunosuppressant FK506 increases functional recovery and nerve regeneration following peripheral nerve injury, Restor. Neurol. Neurosci., 6, 287-296 (1994).
    • (1994) Restor. Neurol. Neurosci. , vol.6 , pp. 287-296
    • Gold, B.G.1    Storm-Dickerson, T.2    Austin, D.R.3
  • 32
    • 0028783373 scopus 로고
    • The immunosuppressant fk506 increases the rate of axonal regeneration in rat sciatic nerve
    • B. G. Gold, K. Katoh, and T. Storm-Dickerson, The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve, J. Neurosci., 15, 7505-7509 (1995).
    • (1995) J. Neurosci. , vol.15 , pp. 7505-7509
    • Gold, B.G.1    Katoh, K.2    Storm-Dickerson, T.3
  • 33
    • 0030839896 scopus 로고    scopus 로고
    • Comparative dose-dependence study of FK506 and cyclosporin A on the rate of axonal regeneration in rat sciatic nerve
    • M. S. Wang, M. Zeleny-Pooley, and B. G. Gold, Comparative dose-dependence study of FK506 and cyclosporin A on the rate of axonal regeneration in rat sciatic nerve, J. Pharmacol. Exp. Ther., 282, 1084-1093 (1997).
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1084-1093
    • Wang, M.S.1    Zeleny-Pooley, M.2    Gold, B.G.3
  • 34
    • 0031406638 scopus 로고    scopus 로고
    • Comparative effects of FK-506, rapamycin and cyclosporin A, on the in vitro differentiation of dorsal root ganglia explants and septal cholinergic neurons
    • A. Carreau, J. Gueugnon, J. Benavides, and X. Vigé, Comparative effects of FK-506, rapamycin and cyclosporin A, on the in vitro differentiation of dorsal root ganglia explants and septal cholinergic neurons, Neuropharmacology, 36, 1755-1762 (1997).
    • (1997) Neuropharmacology , vol.36 , pp. 1755-1762
    • Carreau, A.1    Gueugnon, J.2    Benavides, J.3    Vigé, X.4
  • 38
    • 0030784252 scopus 로고    scopus 로고
    • FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain
    • A. M. Cameron, F. C. Nucifora, Jr., E. T. Fung, D. J. Livingston, R. A. Aldape, C. A. Ross, and S. H. Snyder, FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain, J. Biol. Chem., 272, 27,582-27,588 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 27582-27588
    • Cameron, A.M.1    Nucifora F.C., Jr.2    Fung, E.T.3    Livingston, D.J.4    Aldape, R.A.5    Ross, C.A.6    Snyder, S.H.7
  • 40
    • 0033034203 scopus 로고    scopus 로고
    • Immunophilin FK506 binding protein 52 (not FK506 binding protein 12) mediates the neurotrophic action of FK506
    • B. G. Gold, V. Densmore, W. Shou, M. M. Matzuk, and H. S. Gordon, Immunophilin FK506 binding protein 52 (not FK506 binding protein 12) mediates the neurotrophic action of FK506. J. Pharmacol. Exp. Therap., 289, 1202-1210 (1999).
    • (1999) J. Pharmacol. Exp. Therap. , vol.289 , pp. 1202-1210
    • Gold, B.G.1    Densmore, V.2    Shou, W.3    Matzuk, M.M.4    Gordon, H.S.5
  • 41
    • 0027503073 scopus 로고
    • Gonadal steroids as promoting factors in axonal regeneration
    • K. J. Jones, Gonadal steroids as promoting factors in axonal regeneration, Brain Res. Bull., 30, 491-498 (1993).
    • (1993) Brain Res. Bull. , vol.30 , pp. 491-498
    • Jones, K.J.1
  • 42
    • 0030925683 scopus 로고    scopus 로고
    • Steroid receptor interactions with heat shock protein and immunophilin chaperones
    • W. B. Pratt and D. O. Toft, Steroid receptor interactions with heat shock protein and immunophilin chaperones, Endocr. Rev., 18, 306-360 (1997).
    • (1997) Endocr. Rev. , vol.18 , pp. 306-360
    • Pratt, W.B.1    Toft, D.O.2
  • 43
    • 0031895351 scopus 로고    scopus 로고
    • The hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors
    • W. B. Pratt, The hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors, Proc. Soc. Exp. Biol. Med., 217, 420-434 (1998).
    • (1998) Proc. Soc. Exp. Biol. Med. , vol.217 , pp. 420-434
    • Pratt, W.B.1
  • 44
    • 0032539709 scopus 로고    scopus 로고
    • Two chaperone sites in Hsp90 differing in substrate specificity and ATP dependence
    • T. Scheibel, T. Weikl, and J. Buchner, Two chaperone sites in Hsp90 differing in substrate specificity and ATP dependence, Proc. Natl. Acad. Sci. USA, 95, 1495-1499 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1495-1499
    • Scheibel, T.1    Weikl, T.2    Buchner, J.3
  • 46
    • 0032559196 scopus 로고    scopus 로고
    • The immunosuppressant FK506 increases GAP-43 mRNA levels in axotomized sensory neurons
    • B. G. Gold, J. Y. Yew, and M. Zeleny-Pooley, The immunosuppressant FK506 increases GAP-43 mRNA levels in axotomized sensory neurons, Neuroscience, 241, 25-28 (1998).
    • (1998) Neuroscience , vol.241 , pp. 25-28
    • Gold, B.G.1    Yew, J.Y.2    Zeleny-Pooley, M.3
  • 47
    • 0031027044 scopus 로고    scopus 로고
    • GAP-43: An intrinsic determinant of neuronal development and plasticity
    • L. I. Benowitz, and A. Routtenberg, GAP-43: An intrinsic determinant of neuronal development and plasticity, Trends Neurosci., 20, 84-91 (1997).
    • (1997) Trends Neurosci. , vol.20 , pp. 84-91
    • Benowitz, L.I.1    Routtenberg, A.2
  • 48
    • 0029145441 scopus 로고
    • Dexamethasone enhances level of GAP-43 mRNA after nerve injury and facilitates re-projection of the hypoglossal nerve
    • G. L. Yao and H. Kiyama, Dexamethasone enhances level of GAP-43 mRNA after nerve injury and facilitates re-projection of the hypoglossal nerve, Mol. Brain Res., 32, 308-312 (1995).
    • (1995) Mol. Brain Res. , vol.32 , pp. 308-312
    • Yao, G.L.1    Kiyama, H.2
  • 49
    • 0030785529 scopus 로고    scopus 로고
    • Gonadal steroid regulation of growth-associated protein GAP-43 mRNA expression in axotomized hamster facial motor neurons
    • K. J. Jones, S. M. Drengler, and M. M. Oblinger, Gonadal steroid regulation of growth-associated protein GAP-43 mRNA expression in axotomized hamster facial motor neurons, Neurochem. Res., 22, 1367-1374 (1997).
    • (1997) Neurochem. Res. , vol.22 , pp. 1367-1374
    • Jones, K.J.1    Drengler, S.M.2    Oblinger, M.M.3
  • 51
    • 0031149046 scopus 로고    scopus 로고
    • The c-jun transcription factor - bipotential mediator of neuronal death, survival and regeneration
    • T. Herdegen, P. Skene, and M. Bohr, The c-jun transcription factor - bipotential mediator of neuronal death, survival and regeneration, Trends Neurosci., 20, 227-231 (1997).
    • (1997) Trends Neurosci. , vol.20 , pp. 227-231
    • Herdegen, T.1    Skene, P.2    Bohr, M.3
  • 52
    • 0032557888 scopus 로고    scopus 로고
    • FK506 antagonizes apoptosis and c-jun protein expression in neuronal cultures
    • C. Yardin, F. Terro, M. Lesort, F. Esclaire, and J. Hugon, FK506 antagonizes apoptosis and c-jun protein expression in neuronal cultures, NeuroReport, 9, 2077-2080 (1998).
    • (1998) Neuroreport , vol.9 , pp. 2077-2080
    • Yardin, C.1    Terro, F.2    Lesort, M.3    Esclaire, F.4    Hugon, J.5
  • 53
    • 0027453536 scopus 로고
    • Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity
    • T. M. Dawson, J. P. Steiner, V. L. Dawson, J. L. Dinerman, G. R. Uhl, and S. H. Snyder, Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity, Proc. Natl. Acad. Sci. USA, 90, 9808-9812 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9808-9812
    • Dawson, T.M.1    Steiner, J.P.2    Dawson, V.L.3    Dinerman, J.L.4    Uhl, G.R.5    Snyder, S.H.6
  • 54
    • 0027937489 scopus 로고
    • Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia
    • J. Sharkey and S. P. Butcher, Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia, Nature, 371, 336-339 (1994).
    • (1994) Nature , vol.371 , pp. 336-339
    • Sharkey, J.1    Butcher, S.P.2
  • 55
    • 0030019624 scopus 로고    scopus 로고
    • An immunosuppressant, FK506, protects hippocampal neurons from forebrain ischemia in the mongolian gerbil
    • T. Ide, E. Morikawa, and T. Kirino, An immunosuppressant, FK506, protects hippocampal neurons from forebrain ischemia in the Mongolian gerbil, Neurosci. Lett., 204, 157-160 (1996).
    • (1996) Neurosci. Lett. , vol.204 , pp. 157-160
    • Ide, T.1    Morikawa, E.2    Kirino, T.3
  • 56
    • 0029918506 scopus 로고    scopus 로고
    • Neuroprotective effect of FK506, an immunosuppressant, on transient global ischemia in gerbil
    • T. Tokime, K. Nozaki, and H. Kikuchi, Neuroprotective effect of FK506, an immunosuppressant, on transient global ischemia in gerbil, Neurosci. Lett., 206, 81-84 (1996).
    • (1996) Neurosci. Lett. , vol.206 , pp. 81-84
    • Tokime, T.1    Nozaki, K.2    Kikuchi, H.3
  • 58
    • 0030464736 scopus 로고    scopus 로고
    • Tacrolimus (FK506) ameliorates skilled motor deficits produced by middle cerebral artery occlusion in rats
    • J. Sharkey, J. H. Crawford, S. P. Butcher, and H. M. Marston, Tacrolimus (FK506) ameliorates skilled motor deficits produced by middle cerebral artery occlusion in rats, Stroke, 27, 2282-2286 (1996).
    • (1996) Stroke , vol.27 , pp. 2282-2286
    • Sharkey, J.1    Crawford, J.H.2    Butcher, S.P.3    Marston, H.M.4
  • 59
    • 0029843536 scopus 로고    scopus 로고
    • Postischemic administration of FK506 reduces infarct volume following transient focal brain ischemia
    • S. Kuroda and B. K. Siesjo, Postischemic administration of FK506 reduces infarct volume following transient focal brain ischemia, Neurosci. Res. Commun., 19, 83-90 (1996).
    • (1996) Neurosci. Res. Commun. , vol.19 , pp. 83-90
    • Kuroda, S.1    Siesjo, B.K.2
  • 60
    • 0030850505 scopus 로고    scopus 로고
    • Neuroprotective actions of FK506 in experimental stroke: In vivo evidence against an antiexcitotoxic mechanism
    • S. P. Butcher, D. C. Henshall, Y. Teramura, K. Iwasaki, and J. Sharkey, Neuroprotective actions of FK506 in experimental stroke: In vivo evidence against an antiexcitotoxic mechanism, J. Neurosci., 17, 6939-6946 (1997).
    • (1997) J. Neurosci. , vol.17 , pp. 6939-6946
    • Butcher, S.P.1    Henshall, D.C.2    Teramura, Y.3    Iwasaki, K.4    Sharkey, J.5
  • 62
    • 0027170713 scopus 로고
    • P59 (FK506 binding protein 59) interaction with heat shock proteins is highly conserved and may involve proteins other than steroid receptors
    • P.-K. K. Tai, H. Chang, M. W. Albers, S. L. Schreiber, D. O. Toft, and L. E. Faber, P59 (FK506 binding protein 59) interaction with heat shock proteins is highly conserved and may involve proteins other than steroid receptors, Biochemistry, 32, 8842-8847 (1993).
    • (1993) Biochemistry , vol.32 , pp. 8842-8847
    • Tai, P.-K.K.1    Chang, H.2    Albers, M.W.3    Schreiber, S.L.4    Toft, D.O.5    Faber, L.E.6
  • 64
    • 0028596331 scopus 로고
    • The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor
    • M. J. Czar, J. K. Owens-Grillo, A. W. Yem, K. L. Leach, M. R. Deibel, Jr., M. J. Welsh, and W. B. Pratt, The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor, Mol. Endocrin., 8, 1731-1741 (1994).
    • (1994) Mol. Endocrin. , vol.8 , pp. 1731-1741
    • Czar, M.J.1    Owens-Grillo, J.K.2    Yem, A.W.3    Leach, K.L.4    Deibel M.R., Jr.5    Welsh, M.J.6    Pratt, W.B.7
  • 66
    • 0032006074 scopus 로고    scopus 로고
    • The slow axonal transport of cytoskeletal proteins
    • R. A. Nixon, The slow axonal transport of cytoskeletal proteins, Curr. Opin. Cell Biol., 10, 87-92 (1998).
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 87-92
    • Nixon, R.A.1
  • 67
    • 0344071123 scopus 로고    scopus 로고
    • Direct association of heat shock protein HSP90 and the extracellular signal regulated kinases, ERK1/2. A possible link between estrogen and neurotrophin signaling
    • G. Sétáló, Jr., M. Singh, M. F. Warren, and D. Toran-Allerand, Direct association of heat shock protein HSP90 and the extracellular signal regulated kinases, ERK1/2. A possible link between estrogen and neurotrophin signaling, Soc. Neurosci. Abstr., 23, 1710 (1997).
    • (1997) Soc. Neurosci. Abstr. , vol.23 , pp. 1710
    • Sétáló G., Jr.1    Singh, M.2    Warren, M.F.3    Toran-Allerand, D.4
  • 68
    • 0027384161 scopus 로고
    • Association of protein kinases ERK1 and ERK2 with p75 nerve growth factor receptors
    • C. Volonte, J. M. Angelastro, and L. A. Greene, Association of protein kinases ERK1 and ERK2 with p75 nerve growth factor receptors, J. Biol. Chem., 268, 21,410-21,415 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 21410-21415
    • Volonte, C.1    Angelastro, J.M.2    Greene, L.A.3
  • 69
    • 0028228616 scopus 로고
    • Activation of MAP kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH3T3 cells
    • S. Cowley, H. Paterson, P. Kemp, and C. J. Marshall, Activation of MAP kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH3T3 cells, Cell, 77, 841-852 (1994).
    • (1994) Cell , vol.77 , pp. 841-852
    • Cowley, S.1    Paterson, H.2    Kemp, P.3    Marshall, C.J.4
  • 71
    • 0028202076 scopus 로고
    • Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia
    • W. E. Lyons, E. B. George, T. M. Dawson, J. P. Steiner, and S. H. Snyder, Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia, Proc. Natl. Acad. Sci. USA, 91, 3191-3195 (1994).
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3191-3195
    • Lyons, W.E.1    George, E.B.2    Dawson, T.M.3    Steiner, J.P.4    Snyder, S.H.5
  • 72
    • 0030869037 scopus 로고    scopus 로고
    • Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery
    • K. D. Dittmar, D. R. Demady, L. F. Stancato, P. Krishna, and W. B. Pratt, Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery, J. Biol. Chem., 272, 21,213-21,220 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 21213-21220
    • Dittmar, K.D.1    Demady, D.R.2    Stancato, L.F.3    Krishna, P.4    Pratt, W.B.5
  • 73
    • 0344269321 scopus 로고    scopus 로고
    • An immunophilin is a component of the insect ecdysone receptor (EcR) complex
    • Q. Song, E. S. Alnemri, G. Litwack, and L. I. Gilbert, An immunophilin is a component of the insect ecdysone receptor (EcR) complex, Insect Biochem. Mol. Biol., 27, 973-982 (1997).
    • (1997) Insect Biochem. Mol. Biol. , vol.27 , pp. 973-982
    • Song, Q.1    Alnemri, E.S.2    Litwack, G.3    Gilbert, L.I.4
  • 74
    • 0032211135 scopus 로고    scopus 로고
    • The steroid hormone 20-hydroxyecdysone enhances neurite growth of Drosophila mushroom body neurons isolated during metamorphosis
    • R. Kraft, R. B. Levine, and L. L. Restifo, The steroid hormone 20-hydroxyecdysone enhances neurite growth of Drosophila mushroom body neurons isolated during metamorphosis, J. Neurosci., 18, 8886-8899 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 8886-8899
    • Kraft, R.1    Levine, R.B.2    Restifo, L.L.3
  • 75
    • 0031945523 scopus 로고    scopus 로고
    • Mutation in the Arabidopsis PASTICCINO1 gene, which encodes a new FK506-binding protein-like protein, has a dramatic effect on plant development
    • P. Vittorioso, R. Cowling, J.-D. Faure, M. Caboche, and C. Bellini, Mutation in the Arabidopsis PASTICCINO1 gene, which encodes a new FK506-binding protein-like protein, has a dramatic effect on plant development, Mol. Cell Biol., 18, 3034-3043 (1998).
    • (1998) Mol. Cell Biol. , vol.18 , pp. 3034-3043
    • Vittorioso, P.1    Cowling, R.2    Faure, J.-D.3    Caboche, M.4    Bellini, C.5


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