Geldanamycin, an inhibitor of heat shock protein 90 (Hsp90) mediated signal transduction has anti-inflammatory effects and interacts with glucocorticoid receptor in vivo

British Journal of Pharmacology

Volumn 131, Issue 1, 2000, Pages 13-16

  Bucci, Mariarosaria ^a   Roviezzo, Fiorentina ^a   Cicala, Carla ^a   Sessa, William C ^b   Cirino, Giuseppe ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dexamethasone; Geldanamycin; Glucocorticoid receptor; Hsp90; Inflammation; RU 486

Indexed keywords

ANTIINFLAMMATORY AGENT; CARRAGEENAN; DEXAMETHASONE; GELDANAMYCIN; GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN 90; MIFEPRISTONE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0033817543     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703549     Document Type: Article

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