Geldanamycin protects rat brain through overexpression of HSP70 and reducing brain edema after cerebral focal ischemia

Neurological Research

Volumn 30, Issue 7, 2008, Pages 740-745

  Kwon, Hyung Min ^a,b   Kim, YunHee ^b   Yang, Seung In ^b   Kim, Yong Ju ^b   Lee, Seung Hoon ^b   Yoon, Byung Woo ^b  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

Author keywords

Edema; Geldanamycin; Heat shock protein; Ischemia

Indexed keywords

GELATINASE B; GELDANAMYCIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; DRUG PROTEIN BINDING; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION; SPRAGUE DAWLEY RAT; SUTURING METHOD; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BENZOQUINONES; BRAIN; BRAIN EDEMA; BRAIN ISCHEMIA; CYTOPROTECTION; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HSP70 HEAT-SHOCK PROTEINS; INFARCTION, MIDDLE CEREBRAL ARTERY; LACTAMS, MACROCYCLIC; MALE; MATRIX METALLOPROTEINASE 9; MOLECULAR CHAPERONES; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; PROTEIN FOLDING; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TREATMENT OUTCOME; UP-REGULATION;

EID: 51649109912     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/174313208X289615     Document Type: Article

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