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Volumn 118, Issue 2, 2006, Pages 360-367

Neuroregenerative effects of preinjury FK-506 administration

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; TACROLIMUS;

EID: 33746683259     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.prs.0000227628.43867.5b     Document Type: Article
Times cited : (37)

References (69)
  • 1
    • 0344010071 scopus 로고    scopus 로고
    • FK-506 potentiates NGF-induced neurite outgrowth via the Ras/Raf/MAP kinase pathway
    • Price, R. D., Yamaji, T., and Matsuoka, N. FK-506 potentiates NGF-induced neurite outgrowth via the Ras/Raf/MAP kinase pathway. Br. J. Pharmacol. 140: 825, 2003.
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 825
    • Price, R.D.1    Yamaji, T.2    Matsuoka, N.3
  • 2
    • 12644257556 scopus 로고    scopus 로고
    • Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models
    • Steiner, J. P., Hamilton, G. S., Ross, D. T., et al. Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models. Proc. Natl. Acad. Sci. U.S.A. 94: 2019, 1997.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 2019
    • Steiner, J.P.1    Hamilton, G.S.2    Ross, D.T.3
  • 3
    • 0030975605 scopus 로고    scopus 로고
    • Neurotrophic actions of non-immunosuppressive analogues of immunosuppressive drugs FK-506, rapamycin and cyclosporin A
    • Steiner, J. P., Connolly, M. A., Valentine, H. L., et al. Neurotrophic actions of non-immunosuppressive analogues of immunosuppressive drugs FK-506, rapamycin and cyclosporin A. Nat. Med. 3: 421, 1997.
    • (1997) Nat. Med. , vol.3 , pp. 421
    • Steiner, J.P.1    Connolly, M.A.2    Valentine, H.L.3
  • 4
    • 0028202076 scopus 로고
    • Immunosuppressant FK-506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia
    • Lyons, W. E., George, E. B., Dawson, T. M., et al. Immunosuppressant FK-506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia. Proc. Natl. Acad. Sci. U.S.A. 91: 3191, 1994.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 3191
    • Lyons, W.E.1    George, E.B.2    Dawson, T.M.3
  • 5
    • 0642333766 scopus 로고    scopus 로고
    • Dose-dependent effects of FK-506 on neuroregeneration in a rat model
    • Yang, R. K., Lowe, J. B., III, Sobol, J. B., et al. Dose-dependent effects of FK-506 on neuroregeneration in a rat model. Plast. Reconstr. Surg. 112: 1832, 2003.
    • (2003) Plast. Reconstr. Surg. , vol.112 , pp. 1832
    • Yang, R.K.1    Lowe III, J.B.2    Sobol, J.B.3
  • 6
    • 0038435424 scopus 로고    scopus 로고
    • Low dose discontinued FK-506 treatment enhances peripheral nerve regeneration
    • Chunasuwankul, R., Ayrout, C., Dereli, Z., et al. Low dose discontinued FK-506 treatment enhances peripheral nerve regeneration. Int. Surg. 87: 274, 2002.
    • (2002) Int. Surg. , vol.87 , pp. 274
    • Chunasuwankul, R.1    Ayrout, C.2    Dereli, Z.3
  • 7
    • 0033755467 scopus 로고    scopus 로고
    • Acceleration of peripheral nerve regeneration following FK-506 administration
    • Jost, S. C., Doolabh, V. B., and Mackinnon, S. E. Acceleration of peripheral nerve regeneration following FK-506 administration. Restor. Neurol. Neurosci. 17: 39, 2000.
    • (2000) Restor. Neurol. Neurosci. , vol.17 , pp. 39
    • Jost, S.C.1    Doolabh, V.B.2    Mackinnon, S.E.3
  • 8
    • 0033646279 scopus 로고    scopus 로고
    • Effects of FKBP-12 ligands following tibial nerve injury in rats
    • Becker, D. B., Jensen, J. N., Myckatyn, T. M., et al. Effects of FKBP-12 ligands following tibial nerve injury in rats. J. Reconstr. Microsurg. 16: 613, 2000.
    • (2000) J. Reconstr. Microsurg. , vol.16 , pp. 613
    • Becker, D.B.1    Jensen, J.N.2    Myckatyn, T.M.3
  • 9
    • 0042738107 scopus 로고    scopus 로고
    • FK-506 enhances reinnervation by regeneration and by collateral sprouting of peripheral nerve fibers
    • Udina, E., Ceballos, D., Gold, B. G., et al. FK-506 enhances reinnervation by regeneration and by collateral sprouting of peripheral nerve fibers. Exp. Neurol. 183: 220, 2003.
    • (2003) Exp. Neurol. , vol.183 , pp. 220
    • Udina, E.1    Ceballos, D.2    Gold, B.G.3
  • 10
    • 0036730462 scopus 로고    scopus 로고
    • Bimodal dose-dependence of FK-506 on the rate of axonal regeneration in mouse peripheral nerve
    • Udina, E., Ceballos, D., Verdu, E., et al. Bimodal dose-dependence of FK-506 on the rate of axonal regeneration in mouse peripheral nerve. Muscle Nerve 26: 348, 2002.
    • (2002) Muscle Nerve , vol.26 , pp. 348
    • Udina, E.1    Ceballos, D.2    Verdu, E.3
  • 11
    • 0034775552 scopus 로고    scopus 로고
    • Immunophilin ligand FK506 is neuroprotective for penile innervation
    • Sezen, S. F., Hoke, A., and Burnett, A. L. Immunophilin ligand FK506 is neuroprotective for penile innervation. Nat. Med. 7: 1073, 2001.
    • (2001) Nat. Med. , vol.7 , pp. 1073
    • Sezen, S.F.1    Hoke, A.2    Burnett, A.L.3
  • 12
    • 0034022271 scopus 로고    scopus 로고
    • FK-506 promotes functional recovery in crushed rat sciatic nerve
    • Lee, M., Doolabh, V. B., Mackinnon, S. E., et al. FK-506 promotes functional recovery in crushed rat sciatic nerve. Muscle Nerve 23: 633, 2000.
    • (2000) Muscle Nerve , vol.23 , pp. 633
    • Lee, M.1    Doolabh, V.B.2    Mackinnon, S.E.3
  • 13
    • 0033034203 scopus 로고    scopus 로고
    • Immunophilin FK-506-binding protein 52 (not FK-506-binding protein 12) mediates the neurotrophic action of FK-506
    • Gold, B. G., Densmore, V., Shou, W., et al. Immunophilin FK-506-binding protein 52 (not FK-506-binding protein 12) mediates the neurotrophic action of FK-506. J. Pharmacol. Exp. Ther. 289: 1202, 1999.
    • (1999) J. Pharmacol. Exp. Ther. , vol.289 , pp. 1202
    • Gold, B.G.1    Densmore, V.2    Shou, W.3
  • 14
    • 0033591398 scopus 로고    scopus 로고
    • Efficacy of delayed or discontinuous FK-506 administrations on nerve regeneration in the rat sciatic nerve crush model: Lack of evidence for a conditioning lesion-like effect
    • Gold, B. G., Gordon, H., and Wang, M. S. Efficacy of delayed or discontinuous FK-506 administrations on nerve regeneration in the rat sciatic nerve crush model: Lack of evidence for a conditioning lesion-like effect. Neurosci. Lett. 267: 33, 1999.
    • (1999) Neurosci. Lett. , vol.267 , pp. 33
    • Gold, B.G.1    Gordon, H.2    Wang, M.S.3
  • 15
    • 0030839896 scopus 로고    scopus 로고
    • Comparative dose-dependence study of FK-506 and cyclosporine A on the rate of axonal regeneration in the rat sciatic nerve
    • Wang, M. S., Zeleny-Pooley, M., and Gold, B. G. Comparative dose-dependence study of FK-506 and cyclosporine A on the rate of axonal regeneration in the rat sciatic nerve. J. Pharmacol. Exp. Ther. 282: 1084, 1997.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1084
    • Wang, M.S.1    Zeleny-Pooley, M.2    Gold, B.G.3
  • 16
    • 0028352763 scopus 로고
    • The immunosuppressant FK-506 increase functional recovery nerve regeneration following peripheral nerve injury
    • Gold, B. G., Storm-Dickerson, T., and Austin, D. R. The immunosuppressant FK-506 increase functional recovery nerve regeneration following peripheral nerve injury. Restor. Neurol. Neurosci. 6: 287, 1994.
    • (1994) Restor. Neurol. Neurosci. , vol.6 , pp. 287
    • Gold, B.G.1    Storm-Dickerson, T.2    Austin, D.R.3
  • 17
    • 0028783373 scopus 로고
    • The immunosuppressant FK-506 increases the rate of axonal regeneration in rat sciatic nerve
    • Gold, B. G., Katoh, K., and Storm-Dickerson, T. The immunosuppressant FK-506 increases the rate of axonal regeneration in rat sciatic nerve. J. Neurosci. 15: 7509, 1995.
    • (1995) J. Neurosci. , vol.15 , pp. 7509
    • Gold, B.G.1    Katoh, K.2    Storm-Dickerson, T.3
  • 18
    • 0036114008 scopus 로고    scopus 로고
    • The effects of rapamycin in murine peripheral nerve isografts and allografts
    • Myckatyn, T. M., Ellis, R. A., Grand, A. G., et al. The effects of rapamycin in murine peripheral nerve isografts and allografts. Plast. Reconstr. Surg. 109: 2405, 2002.
    • (2002) Plast. Reconstr. Surg. , vol.109 , pp. 2405
    • Myckatyn, T.M.1    Ellis, R.A.2    Grand, A.G.3
  • 19
    • 0034975002 scopus 로고    scopus 로고
    • Effects of FK-506 on nerve regeneration and reinnervation after graft or tube repair of long nerve grafts
    • Navarro, X., Udina, E., Ceballos, D., et al. Effects of FK-506 on nerve regeneration and reinnervation after graft or tube repair of long nerve grafts. Muscle Nerve 24: 905, 2001.
    • (2001) Muscle Nerve , vol.24 , pp. 905
    • Navarro, X.1    Udina, E.2    Ceballos, D.3
  • 20
    • 0033014586 scopus 로고    scopus 로고
    • FK-506 accelerates functional recovery following nerve grafting in a rat model
    • Doolabh, V. B., and Mackinnon, S. E. FK-506 accelerates functional recovery following nerve grafting in a rat model. Plast. Reconstr. Surg. 103: 1928, 1999.
    • (1999) Plast. Reconstr. Surg. , vol.103 , pp. 1928
    • Doolabh, V.B.1    Mackinnon, S.E.2
  • 21
    • 0033044078 scopus 로고    scopus 로고
    • The effect of the immunosuppressant FK 506 on peripheral nerve regeneration following nerve grafting
    • Fansa, H., Keilhoff, G., Altmann, S., et al. The effect of the immunosuppressant FK 506 on peripheral nerve regeneration following nerve grafting. J. Hand Surg. (Br.) 24: 38, 1999.
    • (1999) J. Hand Surg. (Br.) , vol.24 , pp. 38
    • Fansa, H.1    Keilhoff, G.2    Altmann, S.3
  • 22
    • 0036644307 scopus 로고    scopus 로고
    • Histological and electrophysiological analysis of the peripheral nerve allografts using an immunosuppressant agent
    • Okajima, S., Hojo, T., Tamai, K., et al. Histological and electrophysiological analysis of the peripheral nerve allografts using an immunosuppressant agent. Microsc. Res. Tech. 58: 52, 2002.
    • (2002) Microsc. Res. Tech. , vol.58 , pp. 52
    • Okajima, S.1    Hojo, T.2    Tamai, K.3
  • 23
    • 0035035481 scopus 로고    scopus 로고
    • Clinical outcome following nerve allograft transplantation
    • Mackinnon, S. E., Doolabh, V. B., and Novak, C. B. Clinical outcome following nerve allograft transplantation. Plast. Reconstr. Surg. 107: 1419, 2001.
    • (2001) Plast. Reconstr. Surg. , vol.107 , pp. 1419
    • Mackinnon, S.E.1    Doolabh, V.B.2    Novak, C.B.3
  • 24
    • 0035109501 scopus 로고    scopus 로고
    • FK-506 rescues peripheral nerve allografts in acute rejection
    • Feng, F. Y., Ogden, M. A., Myckatyn, T. M., et al. FK-506 rescues peripheral nerve allografts in acute rejection. J. Neurotrauma 18: 217, 2001.
    • (2001) J. Neurotrauma , vol.18 , pp. 217
    • Feng, F.Y.1    Ogden, M.A.2    Myckatyn, T.M.3
  • 25
    • 0029861973 scopus 로고    scopus 로고
    • Peripheralnerve allotransplantation in rats immunosuppressed with transient or long-term FK-506
    • Weinzweig, N., Grindel, S., Gonzalez, M., et al. Peripheralnerve allotransplantation in rats immunosuppressed with transient or long-term FK-506. J. Reconstr. Microsurg. 12: 451, 1996.
    • (1996) J. Reconstr. Microsurg. , vol.12 , pp. 451
    • Weinzweig, N.1    Grindel, S.2    Gonzalez, M.3
  • 26
    • 0028846836 scopus 로고
    • Peripheral nerve allograft transplantation with FK-506: Functional, histological, and immunological results before and after discontinuation of immunosuppression
    • Buttemeyer, R., Rao, U., and Jones, N. F. Peripheral nerve allograft transplantation with FK-506: Functional, histological, and immunological results before and after discontinuation of immunosuppression. Ann. Plast. Surg. 35: 396, 1995.
    • (1995) Ann. Plast. Surg. , vol.35 , pp. 396
    • Buttemeyer, R.1    Rao, U.2    Jones, N.F.3
  • 27
    • 0036255020 scopus 로고    scopus 로고
    • FK-506 increases peripheral nerve regeneration after chronic axotomy but not after chronic Schwann cell denervation
    • Sulaiman, O. A., Voda, J., Gold, B. G., et al. FK-506 increases peripheral nerve regeneration after chronic axotomy but not after chronic Schwann cell denervation. Exp. Neurol. 175: 127, 2002.
    • (2002) Exp. Neurol. , vol.175 , pp. 127
    • Sulaiman, O.A.1    Voda, J.2    Gold, B.G.3
  • 28
    • 0035190581 scopus 로고    scopus 로고
    • A small dose of the immunosuppressive agent FK-506 (tacrolimus) protects peripheral nerve from ischemic fiber degeneration
    • Kihara, M., Kamijo, M., Nakasaka, Y., et al. A small dose of the immunosuppressive agent FK-506 (tacrolimus) protects peripheral nerve from ischemic fiber degeneration. Muscle Nerve 24: 1601, 2001.
    • (2001) Muscle Nerve , vol.24 , pp. 1601
    • Kihara, M.1    Kamijo, M.2    Nakasaka, Y.3
  • 29
    • 0034509804 scopus 로고    scopus 로고
    • Peripheral nerve and neuromuscular allotransplantation: Current status
    • Bain, J. R. Peripheral nerve and neuromuscular allotransplantation: Current status. Microsurgery 20: 384, 2000.
    • (2000) Microsurgery , vol.20 , pp. 384
    • Bain, J.R.1
  • 30
    • 0033289087 scopus 로고    scopus 로고
    • FK-506 increases the regeneration of spinal cord axons in a pre-degenerated peripheral nerve autograft
    • Wang, M. S., and Gold, B. G. FK-506 increases the regeneration of spinal cord axons in a pre-degenerated peripheral nerve autograft. J. Spinal Cord Med. 22: 287, 1999.
    • (1999) J. Spinal Cord Med. , vol.22 , pp. 287
    • Wang, M.S.1    Gold, B.G.2
  • 31
    • 0027937489 scopus 로고
    • Immunophilins mediate the neuroprotective effects of FK-506 in focal cerebral ischemia
    • Sharkey, J., and Butcher, S. P. Immunophilins mediate the neuroprotective effects of FK-506 in focal cerebral ischemia. Nature 371: 336, 1994.
    • (1994) Nature , vol.371 , pp. 336
    • Sharkey, J.1    Butcher, S.P.2
  • 32
    • 0030019624 scopus 로고    scopus 로고
    • An immunosuppressant, FK-506, protects hippocampal neurons from forebrain ischemia in the Mongolian gerbil
    • Ide, T., Morikawa, E., and Kirino, T. An immunosuppressant, FK-506, protects hippocampal neurons from forebrain ischemia in the Mongolian gerbil. Neurosci. Lett. 204: 157, 1996.
    • (1996) Neurosci. Lett. , vol.204 , pp. 157
    • Ide, T.1    Morikawa, E.2    Kirino, T.3
  • 33
    • 0029918506 scopus 로고    scopus 로고
    • Neuroprotective effect of FK-506, an immunosuppressant, on transient global ischemia in gerbil
    • Tokime, T., Nozaki, K., and Kikuchi, H. Neuroprotective effect of FK-506, an immunosuppressant, on transient global ischemia in gerbil. Neurosci. Lett. 206: 81, 1996.
    • (1996) Neurosci. Lett. , vol.206 , pp. 81
    • Tokime, T.1    Nozaki, K.2    Kikuchi, H.3
  • 34
    • 0030850505 scopus 로고    scopus 로고
    • Neuroprotective actions of FK-506 in experimental stroke: In vivo evidence against an antiexcitotoxic mechanism
    • Butcher, S. P., Henshall, D. C., Teramura, Y., et al. Neuroprotective actions of FK-506 in experimental stroke: In vivo evidence against an antiexcitotoxic mechanism. J. Neurosci. 17: 6939, 1997.
    • (1997) J. Neurosci. , vol.17 , pp. 6939
    • Butcher, S.P.1    Henshall, D.C.2    Teramura, Y.3
  • 35
    • 0027453536 scopus 로고
    • Immunosuppressant FK-506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity
    • Dawson, T. M., Steiner, J. P., Dawson, V. L., et al. Immunosuppressant FK-506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proc. Natl. Acad. Sci. U.S.A. 90: 9808, 1993.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 9808
    • Dawson, T.M.1    Steiner, J.P.2    Dawson, V.L.3
  • 36
    • 0031806507 scopus 로고    scopus 로고
    • Protective effects of FK-506 against glutamate-induced neurotoxicity in retinal cell culture
    • Kikuchi, M., Kashii, S., Mandai, M., et al. Protective effects of FK-506 against glutamate-induced neurotoxicity in retinal cell culture. Invest. Ophthalmol. Vis. Sci. 39: 1227, 1998.
    • (1998) Invest. Ophthalmol. Vis. Sci. , vol.39 , pp. 1227
    • Kikuchi, M.1    Kashii, S.2    Mandai, M.3
  • 37
    • 0028262480 scopus 로고
    • Suppressive effect of FK-506, a novel immunosuppressant, against MPTP-induced dopamine depletion in the striatum of young C57FL/6 mice
    • Kitamura, Y., Itano, Y., Kubo, T., et al. Suppressive effect of FK-506, a novel immunosuppressant, against MPTP-induced dopamine depletion in the striatum of young C57FL/6 mice. J. Neuroimmunol. 50: 221, 1994.
    • (1994) J. Neuroimmunol. , vol.50 , pp. 221
    • Kitamura, Y.1    Itano, Y.2    Kubo, T.3
  • 38
    • 0036717039 scopus 로고    scopus 로고
    • Neuroprotective actions of FK-506 and cyclosporine A on motor neuron survival following neonatal axotomy
    • Iwasaki, Y., Ichikawa, Y., Igarashi, O., et al. Neuroprotective actions of FK-506 and cyclosporine A on motor neuron survival following neonatal axotomy. Neurol. Res. 24: 573, 2002.
    • (2002) Neurol. Res. , vol.24 , pp. 573
    • Iwasaki, Y.1    Ichikawa, Y.2    Igarashi, O.3
  • 39
    • 0032761420 scopus 로고    scopus 로고
    • The immunophilin ligand FK-506, but not GPI-1046, protects against neuronal death and inhibits c-JUN expression in the substantia nigra pars compacta following transection of the rat medial forebrain bundle
    • Winter, C., Schenkel, J., Burger, E., et al. The immunophilin ligand FK-506, but not GPI-1046, protects against neuronal death and inhibits c-JUN expression in the substantia nigra pars compacta following transection of the rat medial forebrain bundle. Neuroscience 95: 753, 2000.
    • (2000) Neuroscience , vol.95 , pp. 753
    • Winter, C.1    Schenkel, J.2    Burger, E.3
  • 40
    • 0036237963 scopus 로고    scopus 로고
    • Axonal regeneration after cold preservation of nerve allografts and immunosuppression with tacrolimus in mice
    • Grand, A., Myckatyn, T., Mackinnon, S., et al. Axonal regeneration after cold preservation of nerve allografts and immunosuppression with tacrolimus in mice. J. Neurosurg. 96: 926, 2002.
    • (2002) J. Neurosurg. , vol.96 , pp. 926
    • Grand, A.1    Myckatyn, T.2    Mackinnon, S.3
  • 41
    • 0037144133 scopus 로고    scopus 로고
    • Neuroprotective and antioxidant properties of FKBP-binding immunophilin ligands are independent on the FKBP12 pathway in human cells
    • Tanaka, K., Fujita, N., Higashi, Y., et al. Neuroprotective and antioxidant properties of FKBP-binding immunophilin ligands are independent on the FKBP12 pathway in human cells. Neurosci. Lett. 330: 147, 2002.
    • (2002) Neurosci. Lett. , vol.330 , pp. 147
    • Tanaka, K.1    Fujita, N.2    Higashi, Y.3
  • 42
    • 0035900877 scopus 로고    scopus 로고
    • The neuroprotective actions of FK-506 binding protein ligands: Neuronal survival is triggered by de novo RNA synthesis, but is independent of inhibition of JNK and calcineurin
    • Klettner, A., Baumgrass, R., Zhang, Y., et al. The neuroprotective actions of FK-506 binding protein ligands: Neuronal survival is triggered by de novo RNA synthesis, but is independent of inhibition of JNK and calcineurin. Mol. Brain Res. 97: 21, 2001.
    • (2001) Mol. Brain Res. , vol.97 , pp. 21
    • Klettner, A.1    Baumgrass, R.2    Zhang, Y.3
  • 43
    • 0034998137 scopus 로고    scopus 로고
    • Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons
    • Gao, X., Dawson, V. L., and Dawson, T. M. Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons. Eur. J. Neurosci. 13: 1683, 2001.
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 1683
    • Gao, X.1    Dawson, V.L.2    Dawson, T.M.3
  • 44
    • 0031258791 scopus 로고    scopus 로고
    • A non-immunosuppressant FKBP-12 ligand increases nerve regeneration
    • Gold, B. G., Zeleny-Pooley, M., Wang, M. S., et al. A non-immunosuppressant FKBP-12 ligand increases nerve regeneration. Exp. Neurol. 147: 269, 1997.
    • (1997) Exp. Neurol. , vol.147 , pp. 269
    • Gold, B.G.1    Zeleny-Pooley, M.2    Wang, M.S.3
  • 45
    • 0037304205 scopus 로고    scopus 로고
    • Effects of delaying FK-506 administration on neuroregeneration in a rodent model
    • Sobol, J. B., Lowe, J. B., III, and Yang, R. K. Effects of delaying FK-506 administration on neuroregeneration in a rodent model. J. Reconstr. Microsurg. 19: 113, 2003.
    • (2003) J. Reconstr. Microsurg. , vol.19 , pp. 113
    • Sobol, J.B.1    Lowe III, J.B.2    Yang, R.K.3
  • 46
    • 1642396949 scopus 로고    scopus 로고
    • Delayed nerve repair is associated with diminished neuroenhancement by FK-506
    • Brenner, M. J., Fox, I. K., Kawamura, D. H., et al. Delayed nerve repair is associated with diminished neuroenhancement by FK-506. Laryngoscope 114: 570, 2004.
    • (2004) Laryngoscope , vol.114 , pp. 570
    • Brenner, M.J.1    Fox, I.K.2    Kawamura, D.H.3
  • 47
    • 0036114008 scopus 로고    scopus 로고
    • The effects of rapamycin in murine peripheral nerve isografts and allografts
    • Myckatyn, T., Ellis, R., Grand, A., et al. The effects of rapamycin in murine peripheral nerve isografts and allografts. Plast. Reconstr. Surg. 109: 2405, 2002.
    • (2002) Plast. Reconstr. Surg. , vol.109 , pp. 2405
    • Myckatyn, T.1    Ellis, R.2    Grand, A.3
  • 48
    • 10044289272 scopus 로고    scopus 로고
    • The immunophilin ligand FK506, but not the P38 kinase inhibitor SB203580, improves function of adult rat muscle reinnervated from transplants of embryonic neurons
    • Grumbles, R. M., Casella, G. T., Rudinsky, M. J., et al. The immunophilin ligand FK506, but not the P38 kinase inhibitor SB203580, improves function of adult rat muscle reinnervated from transplants of embryonic neurons. Neuroscience 130: 619, 2005.
    • (2005) Neuroscience , vol.130 , pp. 619
    • Grumbles, R.M.1    Casella, G.T.2    Rudinsky, M.J.3
  • 49
    • 2642539336 scopus 로고    scopus 로고
    • Comparison of continuous and discontinuous FK506 administration on autograft or allograft repair of sciatic nerve resection
    • Udina, E., Gold, B. G., and Navarro, X. Comparison of continuous and discontinuous FK506 administration on autograft or allograft repair of sciatic nerve resection. Muscle Nerve 29: 812, 2004.
    • (2004) Muscle Nerve , vol.29 , pp. 812
    • Udina, E.1    Gold, B.G.2    Navarro, X.3
  • 50
    • 0038095648 scopus 로고    scopus 로고
    • Insulin-like growth factor-I enhances choleretic action of FK506 in rats
    • Mabuchi, M., Kawamura, I., Takeshita, S., et al. Insulin-like growth factor-I enhances choleretic action of FK506 in rats. Transplant. Proc. 35: 1596, 2003.
    • (2003) Transplant. Proc. , vol.35 , pp. 1596
    • Mabuchi, M.1    Kawamura, I.2    Takeshita, S.3
  • 51
    • 0036237963 scopus 로고    scopus 로고
    • Axonal regeneration after cold preservation of nerve allografts and immunosuppression with tacrolimus in mice
    • Grand, A. G., Myckatyn, T. M., and Mackinnon, S. E. Axonal regeneration after cold preservation of nerve allografts and immunosuppression with tacrolimus in mice. J. Neurosurg. 96: 924, 2002.
    • (2002) J. Neurosurg. , vol.96 , pp. 924
    • Grand, A.G.1    Myckatyn, T.M.2    Mackinnon, S.E.3
  • 52
    • 0028144646 scopus 로고
    • Effect of FK506 and anti-CD4 therapy on fetal pig pancreas xenografts and host lymphoid cells in nod/Lt, CBA, and BALB/c mice
    • Akita, K., Ogawa, M., and Mandel, T. E. Effect of FK506 and anti-CD4 therapy on fetal pig pancreas xenografts and host lymphoid cells in nod/Lt, CBA, and BALB/c mice. Cell Transplant. 3: 61, 1994.
    • (1994) Cell Transplant. , vol.3 , pp. 61
    • Akita, K.1    Ogawa, M.2    Mandel, T.E.3
  • 53
    • 0027416957 scopus 로고
    • Hamster-to-rat heart and liver xenotransplantation with FK506 plus antiproliferative drugs
    • Murase, N., Starzl, T. E., Demetris, A. J., et al. Hamster-to-rat heart and liver xenotransplantation with FK506 plus antiproliferative drugs. Transplantation 55: 701, 1993.
    • (1993) Transplantation , vol.55 , pp. 701
    • Murase, N.1    Starzl, T.E.2    Demetris, A.J.3
  • 54
    • 0030950903 scopus 로고    scopus 로고
    • The effect of duration of muscle denervation on functional recovery in the rat model
    • Kobayashi, J., Mackinnon, S. E., Watanabe, O., et al. The effect of duration of muscle denervation on functional recovery in the rat model. Muscle Nerve 20: 858, 1997.
    • (1997) Muscle Nerve , vol.20 , pp. 858
    • Kobayashi, J.1    Mackinnon, S.E.2    Watanabe, O.3
  • 55
    • 0037352890 scopus 로고    scopus 로고
    • The immunophilin-ligands FK-506 and V-10367 mediate neuroprotection by the heat shock response
    • Klettner, A., and Herdegen, T. The immunophilin-ligands FK-506 and V-10367 mediate neuroprotection by the heat shock response. Br. J. Pharmacol. 138: 1004, 2003.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 1004
    • Klettner, A.1    Herdegen, T.2
  • 56
    • 0033963487 scopus 로고    scopus 로고
    • Immunophilin ligands as a novel treatment for neurological disorders
    • Herdegen, T., Fischer, G., and Gold, B. G. Immunophilin ligands as a novel treatment for neurological disorders. Trends Pharmacol. Sci. 21: 3, 2000.
    • (2000) Trends Pharmacol. Sci. , vol.21 , pp. 3
    • Herdegen, T.1    Fischer, G.2    Gold, B.G.3
  • 57
    • 0032536515 scopus 로고    scopus 로고
    • Oral administration of a non-immunosuppressant FKBP-12 ligand speeds nerve regeneration
    • Gold, B. G., Zeleny-Pooley, M., Chaturvedi, P., et al. Oral administration of a non-immunosuppressant FKBP-12 ligand speeds nerve regeneration. Neuroreport 9: 553, 1998.
    • (1998) Neuroreport , vol.9 , pp. 553
    • Gold, B.G.1    Zeleny-Pooley, M.2    Chaturvedi, P.3
  • 58
    • 0029101382 scopus 로고
    • The cyclosporin A-binding immunophilin CyP-40 and the FK-506-binding immunophilin hsp56 bind to a common site on hsp90 and exit in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor
    • Owens-Grillo, J. K., Hoffmann, K., Hutchison, K. A., et al. The cyclosporin A-binding immunophilin CyP-40 and the FK-506-binding immunophilin hsp56 bind to a common site on hsp90 and exit in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor. J. Biol. Chem. 270: 20479, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20479
    • Owens-Grillo, J.K.1    Hoffmann, K.2    Hutchison, K.A.3
  • 59
    • 0029013233 scopus 로고
    • The 59 kDa FK-506-binding protein, a 90 kDa heat shock protein immunophilin (FKBP59-HBI), is associated with the nucleus, the cytoskeleton and mitotic apparatus
    • Perrot-Applanat, M., Cibert, C., Geraud, G., et al. The 59 kDa FK-506-binding protein, a 90 kDa heat shock protein immunophilin (FKBP59-HBI), is associated with the nucleus, the cytoskeleton and mitotic apparatus. J. Cell Sci. 108: 2037, 1995.
    • (1995) J. Cell Sci. , vol.108 , pp. 2037
    • Perrot-Applanat, M.1    Cibert, C.2    Geraud, G.3
  • 60
    • 0028596331 scopus 로고
    • The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor
    • Czar, M. J., Owens-Grillo, J. K., Yem, A. W., et al. The hsp56 immunophilin component of untransformed steroid receptor complexes is localized both to microtubules in the cytoplasm and to the same nonrandom regions within the nucleus as the steroid receptor. Mol. Endocrinol. 8: 1731, 1994.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1731
    • Czar, M.J.1    Owens-Grillo, J.K.2    Yem, A.W.3
  • 61
    • 0030035694 scopus 로고    scopus 로고
    • An FK-506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones
    • Kralli, A., and Yamamoto, K. R. An FK-506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones. J. Biol. Chem. 271: 17152, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17152
    • Kralli, A.1    Yamamoto, K.R.2
  • 62
    • 0030276887 scopus 로고    scopus 로고
    • The clinical usefulness of the combined use of inhaled beta 2-agonist and inhaled steroid in asthma
    • Yamamoto, C., and Narita, N. The clinical usefulness of the combined use of inhaled beta 2-agonist and inhaled steroid in asthma (in Japanese). Nippon Rinsho 54: 3087, 1996.
    • (1996) Nippon Rinsho , vol.54 , pp. 3087
    • Yamamoto, C.1    Narita, N.2
  • 63
    • 0032411557 scopus 로고    scopus 로고
    • Tacrolimus (FK-506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats
    • Madsen, J. R., MacDonald, P., Irwin, N., et al. Tacrolimus (FK-506) increases neuronal expression of GAP-43 and improves functional recovery after spinal cord injury in rats. Exp. Neurol. 154: 673, 1998.
    • (1998) Exp. Neurol. , vol.154 , pp. 673
    • Madsen, J.R.1    MacDonald, P.2    Irwin, N.3
  • 64
    • 0032559196 scopus 로고    scopus 로고
    • The immunosuppressant FK-506 increases GAP-43 mRNA levels in axotomized sensory neurons
    • Gold, B. G., Yew, J., and Zeleny-Pooley, M. The immunosuppressant FK-506 increases GAP-43 mRNA levels in axotomized sensory neurons. Neurosci. Lett. 241: 25, 1998.
    • (1998) Neurosci. Lett. , vol.241 , pp. 25
    • Gold, B.G.1    Yew, J.2    Zeleny-Pooley, M.3
  • 65
    • 0030785529 scopus 로고    scopus 로고
    • Gonadal steroid regulation of growth-associated protein GAP-43 mRNA expression in axotomized hamster facial motor neurons
    • Jones, K. J., Drengler, S. M., and Oblinger, M. M. Gonadal steroid regulation of growth-associated protein GAP-43 mRNA expression in axotomized hamster facial motor neurons. Neurochem. Res. 22: 1367, 1997.
    • (1997) Neurochem. Res. , vol.22 , pp. 1367
    • Jones, K.J.1    Drengler, S.M.2    Oblinger, M.M.3
  • 66
    • 0029145441 scopus 로고
    • Dexamethasone enhances level of GAP-43 mRNA after nerve injury and facilitates re-projection of the hypoglossal nerve
    • Yao, G. L., and Kiyama, H. Dexamethasone enhances level of GAP-43 mRNA after nerve injury and facilitates re-projection of the hypoglossal nerve. Mol. Brain Res. 32: 308, 1995.
    • (1995) Mol. Brain Res. , vol.32 , pp. 308
    • Yao, G.L.1    Kiyama, H.2
  • 67
    • 0032146734 scopus 로고    scopus 로고
    • Heat shock protein 27: Developmental regulation and expression after peripheral nerve injury
    • Costigan, M., Manion, R. J., Kendall, G., et al. Heat shock protein 27: Developmental regulation and expression after peripheral nerve injury. J. Neurosci. 18: 5891, 1998.
    • (1998) J. Neurosci. , vol.18 , pp. 5891
    • Costigan, M.1    Manion, R.J.2    Kendall, G.3
  • 68
    • 0037386646 scopus 로고    scopus 로고
    • HSP27 is markedly induced in Schwann cell columns and associated regenerating axons
    • Hirata, K., He, J., Hirakawa, Y., et al. HSP27 is markedly induced in Schwann cell columns and associated regenerating axons. Glia 42: 1, 2003.
    • (2003) Glia , vol.42 , pp. 1
    • Hirata, K.1    He, J.2    Hirakawa, Y.3
  • 69
    • 0007444835 scopus 로고
    • The immunosuppressant FK-506 enhances phosphorylation of GAP43: Implications for a role in modulation of growth cone function and neurotransmitter release
    • Steiner, J. P., Dawson, T. M., Fotuhi, C., et al. The immunosuppressant FK-506 enhances phosphorylation of GAP43: Implications for a role in modulation of growth cone function and neurotransmitter release. Soc. Neurosci. Abstr. 18: 603, 1991.
    • (1991) Soc. Neurosci. Abstr. , vol.18 , pp. 603
    • Steiner, J.P.1    Dawson, T.M.2    Fotuhi, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.