-
1
-
-
0034703863
-
Mechanisms of chaperone suppression of polyglutamine disease: Selectivity, synergy and modulation of protein solubility in Drosophila
-
H.Y. Chan, J.M. Warrick, G.L. Gray-Board, H.L. Paulson, and N.M. Bonini Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila Hum. Mol. Genet. 9 2000 2811 2820
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2811-2820
-
-
Chan, H.Y.1
Warrick, J.M.2
Gray-Board, G.L.3
Paulson4
Bonini, N.M.H.L.5
-
2
-
-
0031838352
-
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
-
C.J. Cummings, M.A. Mancini, B. Antalffy, D.B. Defranco, H.T. Orr, and H.Y. Zoghbi Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1 Nat. Genet. 19 1998 148 154
-
(1998)
Nat. Genet.
, vol.19
, pp. 148-154
-
-
Cummings, C.J.1
Mancini, M.A.2
Antalffy, B.3
Defranco, D.B.4
Orr5
Zoghbi, H.Y.H.T.6
-
3
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson’s disease
-
P.K. Auluck, H.Y. Chan, J.Q. Trojanowski, V.M. Lee, and N.M. Bonini Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson’s disease Science 295 2002 865 868
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee4
Bonini, N.M.V.M.5
-
4
-
-
0031944830
-
Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson’s disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity
-
M.C. Irizarry, W. Growdon, T. Gomez-Isla, K. Newell, J.M. George, D.F. Clayton, and B.T. Hyman Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson’s disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity J. Neuropathol. Exp. Neurol. 57 1998 334 337
-
(1998)
J. Neuropathol. Exp. Neurol.
, vol.57
, pp. 334-337
-
-
Irizarry, M.C.1
Growdon, W.2
Gomez-Isla, T.3
Newell, K.4
George, J.M.5
Clayton6
Hyman, B.T.D.F.7
-
5
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
M.G. Spillantini, M.L. Schmidt, V.M. Lee, J.Q. Trojanowski, R. Jakes, and M. Goedert Alpha-synuclein in Lewy bodies Nature 388 1997 839 840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes5
Goedert, M.R.6
-
6
-
-
2942620074
-
Hsp70 reduces alpha-synuclein aggregation and toxicity
-
J. Klucken, Y. Shin, E. Masliah, B.T. Hyman, and P.J. McLean Hsp70 reduces alpha-synuclein aggregation and toxicity J. Biol. Chem. 279 2004 25497 25502
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25497-25502
-
-
Klucken, J.1
Shin, Y.2
Masliah, E.3
Hyman4
McLean, P.J.B.T.5
-
7
-
-
0036846119
-
TorsinA and heat shock proteins act as molecular chaperones: Suppression of alpha-synuclein aggregation
-
P.J. McLean, H. Kawamata, S. Shariff, J. Hewett, N. Sharma, K. Ueda, X.O. Breakefield, and B.T. Hyman TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation J. Neurochem. 83 2002 846 854
-
(2002)
J. Neurochem.
, vol.83
, pp. 846-854
-
-
McLean, P.J.1
Kawamata, H.2
Shariff, S.3
Hewett, J.4
Sharma, N.5
Ueda, K.6
Breakefield7
Hyman, B.T.X.O.8
-
8
-
-
0035363805
-
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington’s disease
-
A. Sittler, R. Lurz, G. Lueder, J. Priller, M.K. Hayer-Hartl, F.U. Hartl, H. Lehrach, and E.R. Wanker Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntingtonâ €™s disease Human. Mol. Genet. 10 2001 1307 1315
-
(2001)
Human. Mol. Genet.
, vol.10
, pp. 1307-1315
-
-
Sittler, A.1
Lurz, R.2
Lueder, G.3
Priller, J.4
Hayer-Hartl, M.K.5
Hartl, F.U.6
Lehrach7
Wanker, E.R.H.8
-
9
-
-
0036852712
-
Pharmacological prevention of parkinson disease in Drosophila
-
P.K. Auluck, and N.M. Bonini Pharmacological prevention of parkinson disease in Drosophila Nat. Med. 8 2002 1185 1186
-
(2002)
Nat. Med.
, vol.8
, pp. 1185-1186
-
-
Auluck1
Bonini, N.M.P.K.2
-
10
-
-
11144356089
-
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation
-
L. Petrucelli, D. Dickson, K. Kehoe, J. Taylor, H. Snyder, A. Grover, M. De Lucia, E. McGowan, J. Lewis, G. Prihar, J. Kim, W.H. Dillmann, S.E. Browne, A. Hall, R. Voellmy, Y. Tsuboi, T.M. Dawson, B. Wolozin, J. Hardy, and M. Hutton CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation Hum. Mol. Genet. 13 2004 703 714
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 703-714
-
-
Petrucelli, L.1
Dickson, D.2
Kehoe, K.3
Taylor, J.4
Snyder, H.5
Grover, A.6
De Lucia, M.7
McGowan, E.8
Lewis, J.9
Prihar, G.10
Kim, J.11
Dillmann, W.H.12
Browne, S.E.13
Hall, A.14
Voellmy, R.15
Tsuboi, Y.16
Dawson, T.M.17
Wolozin, B.18
Hardy19
Hutton, M.J.20
more..
-
11
-
-
0035859226
-
α-Synuclein-enhanced green fluorescent protein fusion proteins form proteasomal sensitive inclusions in primary neurons
-
P.J. McLean, H. Kawamata, and B.T. Hyman α-Synuclein- enhanced green fluorescent protein fusion proteins form proteasomal sensitive inclusions in primary neurons Neuroscience 104 2001 901 912
-
(2001)
Neuroscience
, vol.104
, pp. 901-912
-
-
McLean, P.J.1
Kawamata2
Hyman, B.T.H.3
-
12
-
-
0034708767
-
Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson’s disease-linked mutations
-
P.J. McLean, H. Kawamata, S. Ribich, and B.T. Hyman Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson’s disease-linked mutations J. Biol. Chem. 275 2000 8812 8816
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8812-8816
-
-
McLean, P.J.1
Kawamata, H.2
Ribich3
Hyman, B.T.S.4
-
13
-
-
0032952414
-
Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions
-
S. Engelender, Z. Kaminsky, X. Guo, A.H. Sharp, R.K. Amaravi, J.J. Kleiderlein, R.L. Margolis, J.C. Troncoso, A.A. Lanahan, P.F. Worley, V.L. Dawson, T.M. Dawson, and C.A. Ross Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions Nat. Genet. 22 1999 110 114
-
(1999)
Nat. Genet.
, vol.22
, pp. 110-114
-
-
Engelender, S.1
Kaminsky, Z.2
Guo, X.3
Sharp, A.H.4
Amaravi, R.K.5
Kleiderlein, J.J.6
Margolis, R.L.7
Troncoso, J.C.8
Lanahan, A.A.9
Worley, P.F.10
Dawson, V.L.11
Dawson12
Ross, C.A.T.M.13
-
14
-
-
0034996655
-
Interaction of α-synuclein and synphilin-1: Effect of Parkinson’s disease associated mutations
-
H. Kawamata, P.J. McLean, N. Sharma, and B.T. Hyman Interaction of α-synuclein and synphilin-1: effect of Parkinson†™s disease associated mutations J. Neurochem. 77 2001 929 934
-
(2001)
J. Neurochem.
, vol.77
, pp. 929-934
-
-
Kawamata, H.1
McLean, P.J.2
Sharma3
Hyman, B.T.N.4
-
15
-
-
0034085796
-
Synphilin-1 is present in Lewy bodies in Parkinson’s disease
-
K. Wakabayashi, S. Engelender, M. Yoshimoto, S. Tsuji, C.A. Ross, and H. Takahashi Synphilin-1 is present in Lewy bodies in Parkinson’ s disease Ann. Neurol. 47 2000 521 523
-
(2000)
Ann. Neurol.
, vol.47
, pp. 521-523
-
-
Wakabayashi, K.1
Engelender, S.2
Yoshimoto, M.3
Tsuji, S.4
Ross5
Takahashi, H.C.A.6
-
16
-
-
0023931333
-
Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study
-
S. Kuzuhara, H. Mori, N. Izumiyama, M. Yoshimura, and Y. Ihara Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study Acta. Neuropathol. (Berl.) 75 1988 345 353
-
(1988)
Acta. Neuropathol. (Berl.)
, vol.75
, pp. 345-353
-
-
Kuzuhara, S.1
Mori, H.2
Izumiyama, N.3
Yoshimura4
Ihara, Y.M.5
-
17
-
-
0038386274
-
Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson’s disease
-
M.J. Volles, and P.T. Lansbury Jr. Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson†™s disease Biochemistry 42 2003 7871 7878
-
(2003)
Biochemistry
, vol.42
, pp. 7871-7878
-
-
Lansbury P.T., Jr.1
Volles, M.J.2
-
18
-
-
0037551741
-
Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders
-
B. Caughey, and P.T. Lansbury Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders Annu. Rev. Neurosci. 26 2003 267 298
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 267-298
-
-
Caughey1
Lansbury, P.T.B.2
|