Calcium microdomains at the immunological synapse: How ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation

EMBO Journal

Volumn 30, Issue 19, 2011, Pages 3895-3912

  Quintana, Ariel ^a,f   Pasche, Mathias ^a,e   Junker, Christian ^a   Al Ansary, Dalia ^a   Rieger, Heiko ^b   Kummerow, Carsten ^a   Nuñez, Lucia ^c   Villalobos, Carlos ^c   Meraner, Paul ^d   Becherer, Ute ^a   Rettig, Jens ^a   Niemeyer, Barbara A ^a   Hoth, Markus ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF VALLADOLID   (Spain)

^d LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^e MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; TRANSCRIPTION FACTOR NFAT;

ARTICLE; CALCIUM SIGNALING; CELL MEMBRANE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; MITOCHONDRIAL TARGETING SIGNAL; NANOANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; T LYMPHOCYTE ACTIVATION;

CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL MEMBRANE; CYTOSKELETON; ELECTROPHYSIOLOGY; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOLOGICAL SYNAPSES; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; PROTEIN STRUCTURE, TERTIARY; T-LYMPHOCYTES;

EID: 80053577351     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.289     Document Type: Article

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