-
1
-
-
0032584163
-
An X chromosome gene regulates hematopoietic stem cell kinetics
-
Abkowitz JL, Taboada M, Shelton GH, Catlin SN, Guttorp P, Kiklevich JV (1998) An X chromosome gene regulates hematopoietic stem cell kinetics. Proc Natl Acad Sci U S A 95:3862-3866
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3862-3866
-
-
Abkowitz, J.L.1
Taboada, M.2
Shelton, G.H.3
Catlin, S.N.4
Guttorp, P.5
Kiklevich, J.V.6
-
2
-
-
33645103515
-
The hematopoietic stem cell in its place
-
Adams GB, Scadden DT (2006) The hematopoietic stem cell in its place. Nat Immunol 7:333-337
-
(2006)
Nat Immunol
, vol.7
, pp. 333-337
-
-
Adams, G.B.1
Scadden, D.T.2
-
3
-
-
0037480961
-
Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation
-
Allsopp RC, Morin GB, DePinho R, Harley CB, Weissman IL (2003a) Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation. Blood 102:517-520
-
(2003)
Blood
, vol.102
, pp. 517-520
-
-
Allsopp, R.C.1
Morin, G.B.2
DePinho, R.3
Harley, C.B.4
Weissman, I.L.5
-
4
-
-
0345636016
-
Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells
-
Allsopp RC, Morin GB, Horner JW, DePinho R, Harley CB, Weissman IL (2003b) Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells. Nat Med 9:369-371
-
(2003)
Nat Med
, vol.9
, pp. 369-371
-
-
Allsopp, R.C.1
Morin, G.B.2
Horner, J.W.3
DePinho, R.4
Harley, C.B.5
Weissman, I.L.6
-
5
-
-
0033951775
-
Mitochondrial endogenous oxidative damage has been overestimated
-
Anson RM, Hudson E, Bohr VA (2000) Mitochondrial endogenous oxidative damage has been overestimated. FASEB J 14:355-360
-
(2000)
FASEB J
, vol.14
, pp. 355-360
-
-
Anson, R.M.1
Hudson, E.2
Bohr, V.A.3
-
6
-
-
33748268309
-
Anemia in the elderly-clinical findings and impact on health
-
Balducci L, Ershler WB, Krantz S (2006) Anemia in the elderly-clinical findings and impact on health. Crit Rev Oncol Hematol 58:156-165
-
(2006)
Crit Rev Oncol Hematol
, vol.58
, pp. 156-165
-
-
Balducci, L.1
Ershler, W.B.2
Krantz, S.3
-
7
-
-
0020383765
-
The competitive ability of stem cells from mice with Hertwig's anemia
-
Barker JE, McFarland EC, Bernstein SE (1982) The competitive ability of stem cells from mice with Hertwig's anemia. J Cell Physiol 113:257-260
-
(1982)
J Cell Physiol
, vol.113
, pp. 257-260
-
-
Barker, J.E.1
McFarland, E.C.2
Bernstein, S.E.3
-
8
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
Beausejour CM, Krtolica A, Galimi F, Narita M, Lowe SW, Yaswen P, Campisi J (2003) Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J 22:4212-4222.
-
(2003)
EMBO J
, vol.22
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krtolica, A.2
Galimi, F.3
Narita, M.4
Lowe, S.W.5
Yaswen, P.6
Campisi, J.7
-
9
-
-
10744228523
-
Adult cardiac stem cells are multipotent and support myocardial regeneration
-
Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, Leri A, Kajstura J, Nadal-Ginard B, Anversa P (2003) Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114:763-776
-
(2003)
Cell
, vol.114
, pp. 763-776
-
-
Beltrami, A.P.1
Barlucchi, L.2
Torella, D.3
Baker, M.4
Limana, F.5
Chimenti, S.6
Kasahara, H.7
Rota, M.8
Musso, E.9
Urbanek, K.10
Leri, A.11
Kajstura, J.12
Nadal-Ginard, B.13
Anversa, P.14
-
10
-
-
0032435447
-
Oxidative DNA damage processing and changes with aging
-
Bohr V, Anson RM, Mazur S, Dianov G (1998) Oxidative DNA damage processing and changes with aging. Toxicol Lett 102-103:47-52
-
(1998)
Toxicol Lett
, vol.102-103
, pp. 47-52
-
-
Bohr, V.1
Anson, R.M.2
Mazur, S.3
Dianov, G.4
-
11
-
-
0034941383
-
Limited telomere shortening in hematopoietic stem cells after transplantation
-
discussion 7-8
-
Brummendorf TH, Rufer N, Baerlocher GM, Roosnek E, Lansdorp PM (2001) Limited telomere shortening in hematopoietic stem cells after transplantation. Ann N Y Acad Sci 938:1-7; discussion 7-8
-
(2001)
Ann N Y Acad Sci
, vol.938
, pp. 1-7
-
-
Brummendorf, T.H.1
Rufer, N.2
Baerlocher, G.M.3
Roosnek, E.4
Lansdorp, P.M.5
-
12
-
-
38049044432
-
Intra-organ variation in age-related mutation accumulation in the mouse
-
Busuttil RA, Garcia AM, Reddick RL, Dolle ME, Calder RB, Nelson JF, Vijg J (2007) Intra-organ variation in age-related mutation accumulation in the mouse. PLoS ONE 2:e876
-
(2007)
PLoS ONE
, vol.2
, pp. e876
-
-
Busuttil, R.A.1
Garcia, A.M.2
Reddick, R.L.3
Dolle, M.E.4
Calder, R.B.5
Nelson, J.F.6
Vijg, J.7
-
13
-
-
0035216133
-
Senescence in innate immune responses: Reduced neutrophil phagocytic capacity and CD16 expression in elderly humans
-
Butcher SK, Chahal H, Nayak L, Sinclair A, Henriquez NV, Sapey E, O'Mahony D, Lord JM (2001) Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans. J Leukoc Biol 70:881-886
-
(2001)
J Leukoc Biol
, vol.70
, pp. 881-886
-
-
Butcher, S.K.1
Chahal, H.2
Nayak, L.3
Sinclair, A.4
Henriquez, N.V.5
Sapey, E.6
O'Mahony, D.7
Lord, J.M.8
-
14
-
-
0037133550
-
Embryonic stem cells and somatic cells differ in mutation frequency and type
-
Cervantes RB, Stringer JR, Shao C, Tischfield JA, Stambrook PJ (2002) Embryonic stem cells and somatic cells differ in mutation frequency and type. Proc Natl Acad Sci U S A 99:3586-3590.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3586-3590
-
-
Cervantes, R.B.1
Stringer, J.R.2
Shao, C.3
Tischfield, J.A.4
Stambrook, P.J.5
-
15
-
-
34548208677
-
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation
-
Chambers SM, Shaw CA, Gatza C, Fisk CJ, Donehower LA, Goodell MA (2007) Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol 5:e201
-
(2007)
PLoS Biol
, vol.5
, pp. e201
-
-
Chambers, S.M.1
Shaw, C.A.2
Gatza, C.3
Fisk, C.J.4
Donehower, L.A.5
Goodell, M.A.6
-
16
-
-
7944237675
-
Senescence and functional failure in hematopoietic stem cells
-
Chen J (2004) Senescence and functional failure in hematopoietic stem cells. Exp Hematol 32:1025-1032
-
(2004)
Exp Hematol
, vol.32
, pp. 1025-1032
-
-
Chen, J.1
-
17
-
-
0032920969
-
Development and aging of primitive hematopoietic stem cells in BALB/cBy mice
-
Chen J, Astle CM, Harrison DE (1999) Development and aging of primitive hematopoietic stem cells in BALB/cBy mice. Exp Hematol 27:928-935
-
(1999)
Exp Hematol
, vol.27
, pp. 928-935
-
-
Chen, J.1
Astle, C.M.2
Harrison, D.E.3
-
18
-
-
0034008968
-
Genetic regulation of primitive hematopoietic stem cell senescence
-
Chen J, Astle CM, Harrison DE (2000) Genetic regulation of primitive hematopoietic stem cell senescence. Exp Hematol 28:442-450
-
(2000)
Exp Hematol
, vol.28
, pp. 442-450
-
-
Chen, J.1
Astle, C.M.2
Harrison, D.E.3
-
19
-
-
0142195931
-
Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction
-
Chen J, Astle CM, Harrison DE (2003) Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction. Exp Hematol 31:1097-1103
-
(2003)
Exp Hematol
, vol.31
, pp. 1097-1103
-
-
Chen, J.1
Astle, C.M.2
Harrison, D.E.3
-
20
-
-
0038663068
-
Comparative levels of DNA breaks and sensitivity to oxidative stress in aged and senescent human fibroblasts: A distinctive pattern for centenarians
-
Chevanne M, Caldini R, Tombaccini D, Mocali A, Gori G, Paoletti F (2003) Comparative levels of DNA breaks and sensitivity to oxidative stress in aged and senescent human fibroblasts: a distinctive pattern for centenarians. Biogerontology 4:97-104
-
(2003)
Biogerontology
, vol.4
, pp. 97-104
-
-
Chevanne, M.1
Caldini, R.2
Tombaccini, D.3
Mocali, A.4
Gori, G.5
Paoletti, F.6
-
21
-
-
0344827208
-
Notch-mediated restoration of regenerative potential to aged muscle
-
Conboy IM, Conboy MJ, Smythe GM, Rando TA (2003) Notch-mediated restoration of regenerative potential to aged muscle. Science 302:1575-1577
-
(2003)
Science
, vol.302
, pp. 1575-1577
-
-
Conboy, I.M.1
Conboy, M.J.2
Smythe, G.M.3
Rando, T.A.4
-
22
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433:760-764
-
(2005)
Nature
, vol.433
, pp. 760-764
-
-
Conboy, I.M.1
Conboy, M.J.2
Wagers, A.J.3
Girma, E.R.4
Weissman, I.L.5
Rando, T.A.6
-
23
-
-
0033040497
-
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
-
Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A (1999) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97:703-716
-
(1999)
Cell
, vol.97
, pp. 703-716
-
-
Doetsch, F.1
Caille, I.2
Lim, D.A.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
24
-
-
0035880015
-
Age-related changes of DNA damage recognition and repair capacity in cells of the immune system
-
Doria G, Frasca D (2001) Age-related changes of DNA damage recognition and repair capacity in cells of the immune system. Mech Ageing Dev 122:985-998
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 985-998
-
-
Doria, G.1
Frasca, D.2
-
25
-
-
33847350296
-
Unexplained anaemia in older persons is characterised by low erythropoietin and low levels of pro-inflammatory markers
-
Ferrucci L, Guralnik JM, Bandinelli S, Semba RD, Lauretani F, Corsi A, Ruggiero C, Ershler WB, Longo DL (2007) Unexplained anaemia in older persons is characterised by low erythropoietin and low levels of pro-inflammatory markers. Br J Haematol 136:849-855
-
(2007)
Br J Haematol
, vol.136
, pp. 849-855
-
-
Ferrucci, L.1
Guralnik, J.M.2
Bandinelli, S.3
Semba, R.D.4
Lauretani, F.5
Corsi, A.6
Ruggiero, C.7
Ershler, W.B.8
Longo, D.L.9
-
26
-
-
55449106913
-
Differential expression of novel potential regulators in hematopoietic stem cells
-
Forsberg EC, Prohaska SS, Katzman S, Heffner GC, Stuart JM, Weissman IL (2005) Differential Expression of Novel Potential Regulators in Hematopoietic Stem Cells. PLoS Genet 1:e28.
-
(2005)
PLoS Genet
, vol.1
, pp. e28
-
-
Forsberg, E.C.1
Prohaska, S.S.2
Katzman, S.3
Heffner, G.C.4
Stuart, J.M.5
Weissman, I.L.6
-
27
-
-
0034614379
-
Stem cells: A new lease on life
-
Fuchs E, Segre JA (2000) Stem cells: a new lease on life. Cell 100:143-155
-
(2000)
Cell
, vol.100
, pp. 143-155
-
-
Fuchs, E.1
Segre, J.A.2
-
28
-
-
0034712047
-
Mammalian neural stem cells
-
Gage FH (2000) Mammalian neural stem cells. Science 287:1433-1438
-
(2000)
Science
, vol.287
, pp. 1433-1438
-
-
Gage, F.H.1
-
29
-
-
0028301537
-
Aging affects the levels of DNA damage in postmitotic cells
-
Gaubatz JW, Tan BH (1994) Aging affects the levels of DNA damage in postmitotic cells. Ann N Y Acad Sci 719:97-107
-
(1994)
Ann N Y Acad Sci
, vol.719
, pp. 97-107
-
-
Gaubatz, J.W.1
Tan, B.H.2
-
30
-
-
34247466995
-
Stem cells, aging, niche, adhesion and Cdc42: A model for changes in cell-cell interactions and hematopoietic stem cell aging
-
Geiger H, Koehler A, Gunzer M (2007) Stem Cells, Aging, Niche, Adhesion and Cdc42: A Model for Changes in Cell-Cell Interactions and Hematopoietic Stem Cell Aging. Cell Cycle 6
-
(2007)
Cell Cycle
, pp. 6
-
-
Geiger, H.1
Koehler, A.2
Gunzer, M.3
-
31
-
-
17044426724
-
Regulation of hematopoietic stem cell aging in vivo by a distinct genetic element
-
Geiger H, Rennebeck G, Van Zant G (2005) Regulation of hematopoietic stem cell aging in vivo by a distinct genetic element. Proc Natl Acad Sci U S A 102:5102-5107
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5102-5107
-
-
Geiger, H.1
Rennebeck, G.2
Van Zant, G.3
-
32
-
-
0035892140
-
Age- and stage-specific regulation patterns in the hematopoietic stem cell hierarchy
-
Geiger H, True JM, de Haan G, Van Zant G (2001a) Age- and stage-specific regulation patterns in the hematopoietic stem cell hierarchy. Blood 98:2966-2972
-
(2001)
Blood
, vol.98
, pp. 2966-2972
-
-
Geiger, H.1
True, J.M.2
De Haan, G.3
Van Zant, G.4
-
34
-
-
0036230333
-
The aging of lympho-hematopoietic stem cells
-
Geiger H, Van Zant G (2002) The aging of lympho-hematopoietic stem cells. Nat Immunol 3:329-333
-
(2002)
Nat Immunol
, vol.3
, pp. 329-333
-
-
Geiger, H.1
Van Zant, G.2
-
35
-
-
0032696553
-
The immune system in the elderly: III. Innate immunity
-
Ginaldi L, De Martinis M, D'Ostilio A, Marini L, Loreto MF, Quaglino D (1999) The immune system in the elderly: III. Innate immunity. Immunol Res 20:117-126
-
(1999)
Immunol Res
, vol.20
, pp. 117-126
-
-
Ginaldi, L.1
De Martinis, M.2
D'Ostilio, A.3
Marini, L.4
Loreto, M.F.5
Quaglino, D.6
-
36
-
-
0033948285
-
Mechanisms and implications of the age-associated decrease in DNA repair capacity
-
Goukassian D, Gad F, Yaar M, Eller MS, Nehal US, Gilchrest BA (2000) Mechanisms and implications of the age-associated decrease in DNA repair capacity. FASEB J 14:1325-1334
-
(2000)
FASEB J
, vol.14
, pp. 1325-1334
-
-
Goukassian, D.1
Gad, F.2
Yaar, M.3
Eller, M.S.4
Nehal, U.S.5
Gilchrest, B.A.6
-
37
-
-
0032567975
-
Telomeres and senescence: The history, the experiment, the future
-
Greider CW (1998) Telomeres and senescence: the history, the experiment, the future. Curr Biol 8:R178-R181
-
(1998)
Curr Biol
, vol.8
, pp. R178-R181
-
-
Greider, C.W.1
-
38
-
-
0035964315
-
Does oxidative damage to DNA increase with age?
-
Hamilton ML, Van Remmen H, Drake JA, Yang H, Guo ZM, Kewitt K, Walter CA, Richardson A (2001) Does oxidative damage to DNA increase with age? Proc Natl Acad Sci U S A 98:10469-10474
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10469-10474
-
-
Hamilton, M.L.1
Van Remmen, H.2
Drake, J.A.3
Yang, H.4
Guo, Z.M.5
Kewitt, K.6
Walter, C.A.7
Richardson, A.8
-
39
-
-
0034846017
-
The impact energy metabolism and genome maintenance have on longevity and senescence: Lessons from yeast to mammals
-
Hasty P (2001) The impact energy metabolism and genome maintenance have on longevity and senescence: lessons from yeast to mammals. Mech Ageing Dev 122:1651-1662
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 1651-1662
-
-
Hasty, P.1
-
40
-
-
4544343262
-
Rebuttal to Miller: 'Accelerated aging': A primrose path to insight?'
-
Hasty P, Vijg J (2004) Rebuttal to Miller: 'Accelerated aging': a primrose path to insight?' Aging Cell 3:67-69
-
(2004)
Aging Cell
, vol.3
, pp. 67-69
-
-
Hasty, P.1
Vijg, J.2
-
41
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead P (1961) The serial cultivation of human diploid cell strains. Exp Cell Res 25:585
-
(1961)
Exp Cell Res
, vol.25
, pp. 585
-
-
Hayflick, L.1
Moorhead, P.2
-
42
-
-
0034669532
-
Wild-derived inbred mouse strains have short telomeres
-
Hemann MT, Greider CW (2000) Wild-derived inbred mouse strains have short telomeres. Nucleic Acids Res 28:4474-4478
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 4474-4478
-
-
Hemann, M.T.1
Greider, C.W.2
-
43
-
-
5144231886
-
Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation
-
Hong Y, Stambrook PJ (2004) Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation. Proc Natl Acad Sci U S A 101:14443-14448
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 14443-14448
-
-
Hong, Y.1
Stambrook, P.J.2
-
44
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T (2006) Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 12:446-451
-
(2006)
Nat Med
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
Ohmura, M.7
Naka, K.8
Hosokawa, K.9
Ikeda, Y.10
Suda, T.11
-
45
-
-
0042886929
-
The mitochondrial theory of aging: Dead or alive?
-
Jacobs HT (2003) The mitochondrial theory of aging: dead or alive? Aging Cell 2:11-17
-
(2003)
Aging Cell
, vol.2
, pp. 11-17
-
-
Jacobs, H.T.1
-
46
-
-
0000533818
-
Effect of spleen protection on mortality following x-irradiation
-
Jacobson LO, Marks EK, Robson MJ, Gaston EO, Zirkle RE (1949) Effect of spleen protection on mortality following x-irradiation. J Lab Clin Med 34:1538-1543
-
(1949)
J Lab Clin Med
, vol.34
, pp. 1538-1543
-
-
Jacobson, L.O.1
Marks, E.K.2
Robson, M.J.3
Gaston, E.O.4
Zirkle, R.E.5
-
47
-
-
33749172559
-
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16 (INK4a)
-
Janzen V, Forkert R, Fleming HE, Saito Y, Waring MT, Dombkowski DM, Cheng T, Depinho RA, Sharpless NE, Scadden DT (2006) Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16 (INK4a). Nature 443:421-426
-
(2006)
Nature
, vol.443
, pp. 421-426
-
-
Janzen, V.1
Forkert, R.2
Fleming, H.E.3
Saito, Y.4
Waring, M.T.5
Dombkowski, D.M.6
Cheng, T.7
Depinho, R.A.8
Sharpless, N.E.9
Scadden, D.T.10
-
48
-
-
0032806359
-
Senescent human fibroblasts have elevated Ku86 proteolytic cleavage activity
-
Jeng YW, Chao HC, Chiu CF, Chou WG (1999) Senescent human fibroblasts have elevated Ku86 proteolytic cleavage activity. Mutat Res 435:225-232
-
(1999)
Mutat Res
, vol.435
, pp. 225-232
-
-
Jeng, Y.W.1
Chao, H.C.2
Chiu, C.F.3
Chou, W.G.4
-
49
-
-
34047095284
-
Mitochondrial DNA mutations and aging: A case closed?
-
Khrapko K, Vijg J (2007) Mitochondrial DNA mutations and aging: a case closed? Nat Genet 39:445-446
-
(2007)
Nat Genet
, vol.39
, pp. 445-446
-
-
Khrapko, K.1
Vijg, J.2
-
50
-
-
33845467828
-
Maintaining hematopoietic stem cells in the vascular niche
-
Kiel MJ, Morrison SJ (2006) Maintaining Hematopoietic Stem Cells in the Vascular Niche. Immunity 25:862-864
-
(2006)
Immunity
, vol.25
, pp. 862-864
-
-
Kiel, M.J.1
Morrison, S.J.2
-
51
-
-
21244463426
-
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
-
Kiel MJ, Yilmaz OH, Iwashita T, Terhorst C, Morrison SJ (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121:1109-1121
-
(2005)
Cell
, vol.121
, pp. 1109-1121
-
-
Kiel, M.J.1
Yilmaz, O.H.2
Iwashita, T.3
Terhorst, C.4
Morrison, S.J.5
-
52
-
-
0038806560
-
Major age-related changes of mouse hematopoietic stem/progenitor cells
-
Kim M, Moon HB, Spangrude GJ (2003) Major age-related changes of mouse hematopoietic stem/progenitor cells. Ann N Y Acad Sci 996:195-208
-
(2003)
Ann N Y Acad Sci
, vol.996
, pp. 195-208
-
-
Kim, M.1
Moon, H.B.2
Spangrude, G.J.3
-
53
-
-
41349096243
-
Telomeres, stem cells, and hematology
-
Lansdorp PM (2008) Telomeres, stem cells, and hematology. Blood 111:1759-1766
-
(2008)
Blood
, vol.111
, pp. 1759-1766
-
-
Lansdorp, P.M.1
-
54
-
-
23744439044
-
Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells
-
Liang Y, Van Zant G, Szilvassy SJ (2005) Effects of aging on the homing and engraftment of murine hematopoietic stem and progenitor cells. Blood 106:1479-1487
-
(2005)
Blood
, vol.106
, pp. 1479-1487
-
-
Liang, Y.1
Van Zant, G.2
Szilvassy, S.J.3
-
55
-
-
33845222483
-
Purification of hematopoietic stem cells using the side population
-
Lin KK, Goodell MA (2006) Purification of hematopoietic stem cells using the side population. Methods Enzymol 420:255-264
-
(2006)
Methods Enzymol
, vol.420
, pp. 255-264
-
-
Lin, K.K.1
Goodell, M.A.2
-
56
-
-
1142275269
-
Age-related changes in lymphocyte development and function
-
Linton PJ, Dorshkind K (2004) Age-related changes in lymphocyte development and function. Nat Immunol 5:133-139
-
(2004)
Nat Immunol
, vol.5
, pp. 133-139
-
-
Linton, P.J.1
Dorshkind, K.2
-
57
-
-
0028912580
-
Age-related declines in hematopoietic reserve capacity
-
Lipschitz DA (1995) Age-related declines in hematopoietic reserve capacity. Semin Oncol 22:3-5
-
(1995)
Semin Oncol
, vol.22
, pp. 3-5
-
-
Lipschitz, D.A.1
-
59
-
-
0035975703
-
Neutrophil ageing and immunesenescence
-
Lord JM, Butcher S, Killampali V, Lascelles D, Salmon M (2001) Neutrophil ageing and immunesenescence. Mech Ageing Dev 122:1521-1535
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 1521-1535
-
-
Lord, J.M.1
Butcher, S.2
Killampali, V.3
Lascelles, D.4
Salmon, M.5
-
60
-
-
0031715965
-
Altered stem cell regeneration in irradiated intestinal crypts of senescent mice
-
Martin K, Potten CS, Roberts SA, Kirkwood TB (1998) Altered stem cell regeneration in irradiated intestinal crypts of senescent mice. J Cell Sci 111(Pt 16):2297-2303
-
(1998)
J Cell Sci
, vol.111
, pp. 2297-2303
-
-
Martin, K.1
Potten, C.S.2
Roberts, S.A.3
Kirkwood, T.B.4
-
61
-
-
36248957063
-
Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues
-
Massberg S, Schaerli P, Knezevic-Maramica I, Kollnberger M, Tubo N, Moseman EA, Huff IV, Junt T, Wagers AJ, Mazo IB, von Andrian UH (2007) Immunosurveillance by Hematopoietic Progenitor Cells Trafficking through Blood, Lymph, and Peripheral Tissues. Cell 131:994-1008
-
(2007)
Cell
, vol.131
, pp. 994-1008
-
-
Massberg, S.1
Schaerli, P.2
Knezevic-Maramica, I.3
Kollnberger, M.4
Tubo, N.5
Moseman, E.A.6
Huff, I.V.7
Junt, T.8
Wagers, A.J.9
Mazo, I.B.10
Von Andrian, U.H.11
-
62
-
-
0030894092
-
Stem cells in the central nervous system
-
McKay R (1997) Stem cells in the central nervous system. Science 276:66-71
-
(1997)
Science
, vol.276
, pp. 66-71
-
-
McKay, R.1
-
63
-
-
4544328104
-
Rebuttal to Hasty and Vijg: 'Accelerating aging by mouse reverse genetics: A rational approach to understanding longevity'
-
Miller RA (2004) Rebuttal to Hasty and Vijg: 'Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity'. Aging Cell 3:53-54
-
(2004)
Aging Cell
, vol.3
, pp. 53-54
-
-
Miller, R.A.1
-
64
-
-
0030248792
-
Telomerase activity in hematopoietic cells is associated with self-renewal potential
-
Morrison SJ, Prowse KR, Ho P, Weissman IL (1996a) Telomerase activity in hematopoietic cells is associated with self-renewal potential. Immunity 5:207-216
-
(1996)
Immunity
, vol.5
, pp. 207-216
-
-
Morrison, S.J.1
Prowse, K.R.2
Ho, P.3
Weissman, I.L.4
-
66
-
-
0029813378
-
The aging of hematopoietic stem cells [see comments]
-
Morrison SJ, Wandycz AM, Akashi K, Globerson A, Weissman IL (1996b) The aging of hematopoietic stem cells [see comments]. Nat Med 2:1011-1016
-
(1996)
Nat Med
, vol.2
, pp. 1011-1016
-
-
Morrison, S.J.1
Wandycz, A.M.2
Akashi, K.3
Globerson, A.4
Weissman, I.L.5
-
68
-
-
0033003685
-
Bone marrow CD34 cells generate fewer T cells in vitro with increasing age and following chemotherapy
-
Offner F, Kerre T, De Smedt M, Plum J (1999) Bone marrow CD34 cells generate fewer T cells in vitro with increasing age and following chemotherapy. Br J Haematol 104:801-808
-
(1999)
Br J Haematol
, vol.104
, pp. 801-808
-
-
Offner, F.1
Kerre, T.2
De Smedt, M.3
Plum, J.4
-
69
-
-
0142027772
-
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
-
Oh H, Bradfute SB, Gallardo TD, Nakamura T, Gaussin V, Mishina Y, Pocius J, Michael LH, Behringer RR, Garry DJ, Entman ML, Schneider MD (2003) Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A 100:12313-12318
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12313-12318
-
-
Oh, H.1
Bradfute, S.B.2
Gallardo, T.D.3
Nakamura, T.4
Gaussin, V.5
Mishina, Y.6
Pocius, J.7
Michael, L.H.8
Behringer, R.R.9
Garry, D.J.10
Entman, M.L.11
Schneider, M.D.12
-
70
-
-
0029796633
-
Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
-
Osawa M, Hanada K, Hamada H, Nakauchi H (1996) Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 273:242-245
-
(1996)
Science
, vol.273
, pp. 242-245
-
-
Osawa, M.1
Hanada, K.2
Hamada, H.3
Nakauchi, H.4
-
71
-
-
0042195820
-
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
-
Parrinello S, Samper E, Krtolica A, Goldstein J, Melov S, Campisi J (2003) Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat Cell Biol 5:741-747
-
(2003)
Nat Cell Biol
, vol.5
, pp. 741-747
-
-
Parrinello, S.1
Samper, E.2
Krtolica, A.3
Goldstein, J.4
Melov, S.5
Campisi, J.6
-
73
-
-
34250007142
-
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
-
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL (2007) Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 447:725-729
-
(2007)
Nature
, vol.447
, pp. 725-729
-
-
Rossi, D.J.1
Bryder, D.2
Seita, J.3
Nussenzweig, A.4
Hoeijmakers, J.5
Weissman, I.L.6
-
74
-
-
21544467270
-
Cell intrinsic alterations underlie hematopoietic stem cell aging
-
Rossi DJ, Bryder D, Zahn JM, Ahlenius H, Sonu R, Wagers AJ, Weissman IL (2005) Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc Natl Acad Sci U S A 102:9194-9199
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9194-9199
-
-
Rossi, D.J.1
Bryder, D.2
Zahn, J.M.3
Ahlenius, H.4
Sonu, R.5
Wagers, A.J.6
Weissman, I.L.7
-
75
-
-
33745635043
-
The stem-cell niche as an entity of action
-
Scadden DT (2006) The stem-cell niche as an entity of action. Nature 441:1075-1079
-
(2006)
Nature
, vol.441
, pp. 1075-1079
-
-
Scadden, D.T.1
-
76
-
-
0242585031
-
DNA damage recognition and repair capacities in human naive and memory T cells from peripheral blood of young and elderly subjects
-
Scarpaci S, Frasca D, Barattini P, Guidi L, Doria G (2003) DNA damage recognition and repair capacities in human naive and memory T cells from peripheral blood of young and elderly subjects. Mech Ageing Dev 124:517-524
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 517-524
-
-
Scarpaci, S.1
Frasca, D.2
Barattini, P.3
Guidi, L.4
Doria, G.5
-
77
-
-
85047689866
-
Telomeres, stem cells, senescence, and cancer
-
Sharpless NE, DePinho RA (2004) Telomeres, stem cells, senescence, and cancer. J Clin Invest 113:160-168
-
(2004)
J Clin Invest
, vol.113
, pp. 160-168
-
-
Sharpless, N.E.1
DePinho, R.A.2
-
78
-
-
16644396985
-
Quantitative trait analysis in the investigation of function and aging of hematopoietic stem cells
-
Snoeck HW (2005) Quantitative trait analysis in the investigation of function and aging of hematopoietic stem cells. Methods Mol Med 105:47-62
-
(2005)
Methods Mol Med
, vol.105
, pp. 47-62
-
-
Snoeck, H.W.1
-
79
-
-
0037417893
-
Molecular features of adult mouse small intestinal epithelial progenitors
-
Stappenbeck TS, Mills JC, Gordon JI (2003) Molecular features of adult mouse small intestinal epithelial progenitors. Proc Natl Acad Sci U S A 100:1004-1009
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1004-1009
-
-
Stappenbeck, T.S.1
Mills, J.C.2
Gordon, J.I.3
-
80
-
-
0034613690
-
Age-associated characteristics of murine hematopoietic stem cells
-
Record as supplied by publisher
-
Sudo K, Ema H, Morita Y, Nakauchi H (2000) Age-associated Characteristics of Murine Hematopoietic Stem Cells. J Exp Med 192:1273-1280 [Record as supplied by publisher]
-
(2000)
J Exp Med
, vol.192
, pp. 1273-1280
-
-
Sudo, K.1
Ema, H.2
Morita, Y.3
Nakauchi, H.4
-
81
-
-
0034718599
-
Enrichment for murine keratinocyte stem cells based on cell surface phenotype
-
Tani H, Morris RJ, Kaur P (2000) Enrichment for murine keratinocyte stem cells based on cell surface phenotype. Proc Natl Acad Sci U S A 97:10960-10965
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10960-10965
-
-
Tani, H.1
Morris, R.J.2
Kaur, P.3
-
82
-
-
0347600946
-
Mitochondrial DNA mutations in human colonic crypt stem cells
-
Taylor RW, Barron MJ, Borthwick GM, Gospel A, Chinnery PF, Samuels DC, Taylor GA, Plusa SM, Needham SJ, Greaves LC, Kirkwood TB, Turnbull DM (2003) Mitochondrial DNA mutations in human colonic crypt stem cells. J Clin Invest 112:1351-1360
-
(2003)
J Clin Invest
, vol.112
, pp. 1351-1360
-
-
Taylor, R.W.1
Barron, M.J.2
Borthwick, G.M.3
Gospel, A.4
Chinnery, P.F.5
Samuels, D.C.6
Taylor, G.A.7
Plusa, S.M.8
Needham, S.J.9
Greaves, L.C.10
Kirkwood, T.B.11
Turnbull, D.M.12
-
83
-
-
12144291084
-
Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression
-
Torella D, Rota M, Nurzynska D, Musso E, Monsen A, Shiraishi I, Zias E, Walsh K, Rosenzweig A, Sussman MA, Urbanek K, Nadal-Ginard B, Kajstura J, Anversa P, Leri A (2004) Cardiac Stem Cell and Myocyte Aging, Heart Failure, and Insulin-Like Growth Factor-1 Overexpression. Circ Res.
-
(2004)
Circ Res
-
-
Torella, D.1
Rota, M.2
Nurzynska, D.3
Musso, E.4
Monsen, A.5
Shiraishi, I.6
Zias, E.7
Walsh, K.8
Rosenzweig, A.9
Sussman, M.A.10
Urbanek, K.11
Nadal-Ginard, B.12
Kajstura, J.13
Anversa, P.14
Leri, A.15
-
85
-
-
0028914587
-
Marrow- and spleen-seeding efficiencies of all murine hematopoietic stem cell subsets are decreased by preincubation with hematopoietic growth factors
-
van der Loo JC, Ploemacher RE (1995) Marrow- and spleen-seeding efficiencies of all murine hematopoietic stem cell subsets are decreased by preincubation with hematopoietic growth factors. Blood 85:2598-2606
-
(1995)
Blood
, vol.85
, pp. 2598-2606
-
-
Van Der Loo, J.C.1
Ploemacher, R.E.2
-
87
-
-
0025281056
-
Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice
-
Van Zant G, Holland BP, Eldridge PW, Chen JJ (1990) Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice. J Exp Med 171:1547-1565
-
(1990)
J Exp Med
, vol.171
, pp. 1547-1565
-
-
Van Zant, G.1
Holland, B.P.2
Eldridge, P.W.3
Chen, J.J.4
-
88
-
-
0041666387
-
The role of stem cells in aging
-
Van Zant G, Liang Y (2003) The role of stem cells in aging. Exp Hematol 31:659-672
-
(2003)
Exp Hematol
, vol.31
, pp. 659-672
-
-
Van Zant, G.1
Liang, Y.2
-
89
-
-
0028077099
-
Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
-
Vaziri H, Dragowska W, Allsopp RC, Thomas TE, Harley CB, Lansdorp PM (1994) Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. Proc Natl Acad Sci U S A 91:9857-9860
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allsopp, R.C.3
Thomas, T.E.4
Harley, C.B.5
Lansdorp, P.M.6
-
90
-
-
34047116291
-
Mitochondrial point mutations do not limit the natural lifespan of mice
-
Vermulst M, Bielas JH, Kujoth GC, Ladiges WC, Rabinovitch PS, Prolla TA, Loeb LA (2007) Mitochondrial point mutations do not limit the natural lifespan of mice. Nat Genet 39:540-543
-
(2007)
Nat Genet
, vol.39
, pp. 540-543
-
-
Vermulst, M.1
Bielas, J.H.2
Kujoth, G.C.3
Ladiges, W.C.4
Rabinovitch, P.S.5
Prolla, T.A.6
Loeb, L.A.7
-
91
-
-
0037198009
-
Large genome rearrangements as a primary cause of aging
-
Vijg J, Dolle ME (2002) Large genome rearrangements as a primary cause of aging. Mech Ageing Dev 123:907-915
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 907-915
-
-
Vijg, J.1
Dolle, M.E.2
-
92
-
-
33846604728
-
Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes
-
accepted for publication
-
Wang L, Yang L, Debidda M, Witte D, Zheng Y (2007) Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes. Proc Natl Acad Sci (accepted for publication)
-
(2007)
Proc Natl Acad Sci
-
-
Wang, L.1
Yang, L.2
Debidda, M.3
Witte, D.4
Zheng, Y.5
-
93
-
-
13844273246
-
Head-to-head debate between Richard Miller and Paul Hasty/Jan Vijg. Aging Cell Vol. 3, Issue 2 (2004)
-
Warner HR (2004) Head-to-head debate between Richard Miller and Paul Hasty/Jan Vijg. Aging Cell Vol. 3, Issue 2 (2004). Aging Cell 3:141-142
-
(2004)
Aging Cell
, vol.3
, pp. 141-142
-
-
Warner, H.R.1
-
94
-
-
41349087734
-
CD150-side population cells represent a functionally distinct population of long-term hematopoietic stem cells
-
Weksberg DC, Chambers SM, Boles NC, Goodell MA (2008) CD150-side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood 111:2444-2451
-
(2008)
Blood
, vol.111
, pp. 2444-2451
-
-
Weksberg, D.C.1
Chambers, S.M.2
Boles, N.C.3
Goodell, M.A.4
-
95
-
-
0024492263
-
Immunodeficiency in old age
-
Wick G, Huber LA, Offner F, Winter U, Bock G, Schauenstein K, Jurgens G, Traill KN (1989) Immunodeficiency in old age. Curr Probl Dermatol 18:120-130
-
(1989)
Curr Probl Dermatol
, vol.18
, pp. 120-130
-
-
Wick, G.1
Huber, L.A.2
Offner, F.3
Winter, U.4
Bock, G.5
Schauenstein, K.6
Jurgens, G.7
Traill, K.N.8
-
96
-
-
33644827383
-
Bone-marrow haematopoietic-stem-cell niches
-
Wilson A, Trumpp A (2006) Bone-marrow haematopoietic-stem-cell niches. Nat Rev Immunol 6:93-106
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 93-106
-
-
Wilson, A.1
Trumpp, A.2
-
97
-
-
0035976526
-
Physiological migration of hematopoietic stem and progenitor cells
-
Wright DE, Wagers AJ, Gulati AP, Johnson FL, Weissman IL (2001) Physiological migration of hematopoietic stem and progenitor cells. Science 294:1933-1936
-
(2001)
Science
, vol.294
, pp. 1933-1936
-
-
Wright, D.E.1
Wagers, A.J.2
Gulati, A.P.3
Johnson, F.L.4
Weissman, I.L.5
-
98
-
-
33749365721
-
Increased hematopoietic stem cell mobilization in aged mice
-
Xing Z, Ryan MA, Daria D, Nattamai KJ, Van Zant G, Wang L, Zheng Y, Geiger H (2006) Increased hematopoietic stem cell mobilization in aged mice. Blood 108:2190-2197
-
(2006)
Blood
, vol.108
, pp. 2190-2197
-
-
Xing, Z.1
Ryan, M.A.2
Daria, D.3
Nattamai, K.J.4
Van Zant, G.5
Wang, L.6
Zheng, Y.7
Geiger, H.8
-
99
-
-
34247621290
-
Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow
-
Yang L, Wang L, Geiger H, Cancelas JA, Mo J, Zheng Y (2007) Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow. Proc Natl Acad Sci U S A 104:5091-5096
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5091-5096
-
-
Yang, L.1
Wang, L.2
Geiger, H.3
Cancelas, J.A.4
Mo, J.5
Zheng, Y.6
-
100
-
-
31544481865
-
SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity
-
Yilmaz OH, Kiel MJ, Morrison SJ (2006) SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood 107:924-930
-
(2006)
Blood
, vol.107
, pp. 924-930
-
-
Yilmaz, O.H.1
Kiel, M.J.2
Morrison, S.J.3
-
101
-
-
33646435309
-
The stem cell niches in bone
-
Yin T, Li L (2006) The stem cell niches in bone. J Clin Invest 116:1195-1201
-
(2006)
J Clin Invest
, vol.116
, pp. 1195-1201
-
-
Yin, T.1
Li, L.2
-
102
-
-
0036125605
-
The in vivo levels of DNA alkylation products in human lymphocytes are not age dependent: An assay of 7-methyl- and 7-(2-hydroxyethyl)-guanine DNA adducts
-
Zhao C, Hemminki K (2002) The in vivo levels of DNA alkylation products in human lymphocytes are not age dependent: an assay of 7-methyl- and 7-(2-hydroxyethyl)-guanine DNA adducts. Carcinogenesis 23:307-310
-
(2002)
Carcinogenesis
, vol.23
, pp. 307-310
-
-
Zhao, C.1
Hemminki, K.2
|