Senescence and functional failure in hematopoietic stem cells

Experimental Hematology

Volumn 32, Issue 11, 2004, Pages 1025-1032

  Chen, Jichun ^a,b  

^a Lung   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL;

BONE MARROW TRANSPLANTATION; CELL DIVISION; CELL FUNCTION; CELL LINE; CELL POPULATION; CELL PROLIFERATION; FUNCTIONAL ASSESSMENT; GENE MUTATION; GENETIC REGULATION; GENETICS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; LEUKOCYTE; LIFESPAN; MOLECULAR CLONING; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SENESCENCE; SENSITIVITY ANALYSIS; TELOMERE; UPREGULATION;

ANIMALS; CELL AGING; CELL PROLIFERATION; CLONE CELLS; HEMATOPOIETIC STEM CELLS; HUMANS; TELOMERE;

ANIMALIA;

EID: 7944237675     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2004.08.001     Document Type: Review

References (73)

1. J. Chen, C.M. Astle, and D.E. Harrison Development and aging of primitive hematopoietic stem cells in BALB/cBy mice Exp Hematol 27 1999 928 935
2. J. Chen, C.M. Astle, C.E. Muller-Sieburg, and D.E. Harrison Primitive hemopoietic stem cell function in vivo is uniquely high in the CXB-12 mouse strain Blood 96 2000 4124 4131
3. D.E. Harrison, C.M. Astle, and M. Stone Numbers and functions of transplantable primitive immunohematopoietic stem cells. Effects of age J Immunol 142 11 1989 3833 3840
4. D.E. Harrison, C.T. Jordan, R.K. Zhong, and C.M. Astle Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations Exp Hematol 21 2 1993 206 219
5. C.E. Muller-Sieburg, and R. Riblet Genetic control of the frequency of hematopoietic stem cells in mice: Mapping of a candidate locus to chromosome 1 J Exp Med 183 1996 1141 1150
6. M. Osawa, K. Hanada, H. Hamada, and H. Nakauchi Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell Science 273 5272 1996 242 245
7. G.J. Spangrude, S. Heimfeld, and I.L. Weissman Purification and characterization of mouse hematopoietic stem cells Science 241 1988 58 62
8. Y. Zhao, Y. Zhan, Y. Lin, J. Yang, D.E. Harrison, and W.F. Anderson Regulation of murine hematopoietic stem cell proliferation in vivo Blood 96 2000 3016 3022
9. J.L. Abkowitz, D. Golinelli, D.E. Harrison, and P. Guttorp In vivo kinetics of murine hemopoietic stem cells Blood 96 10 2000 3399 3405
10. J.L. Abkowitz, S.N. Catlin, M.T. McCallie, and P. Guttorp Evidence that the number of hematopoietic stem cells per animal is conserved in mammals Blood 100 7 2002 2665 2667
11. S.J. Morrison, A.M. Wandycz, K. Akashi, A. Globerson, and I.L. Weissman The aging of hematopoietic stem cells [see comments] Nat Med 2 9 1996 1011 1016
12. G.J. Spangrude, J. Klein, S. Heimfeld, Y. Aihara, and I.L. Weissman Two monoclonal antibodies identify thymic-repopulating cells in mouse bone marrow J Immunol 142 1989 425 430
13. N.S. Young, and A.J. Barrett Immune mediation of pancytopenia in myelodysplastic syndromes: pathophysiology and treatment J.M. Bennett The myelodysplastic syndromes: pathobiology and clinical mangagement 2002 Marcel Dekker New York 373 398
14. N.S. Young Acquired aplastic anemia Ann Intern Med 136 2002 534 546
15. P.F. Fogarty, H. Yamaguchi, and A. Wiestner Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA Lancet 362 2003 1628 1630
16. L. Hayflick, and P.S. Moorhead The serial cultivation of human diploid cell strains Exp Cell Res 25 1961 585 621
17. L. Hayflick The limited in vitro lifetime of human diploid cell strains Exp Cell Res 37 3 1965 614 636
18. L. Hayflick The future of ageing Nature 408 2000 267 269
19. L. Hayflick The illusion of cell immortality Br J Cancer 83 2000 841 846
20. The Staff of The Jackson Laboratory Handbook on Genetically Standardized Jax Mice 1997 The Jackson Laboratory Bar Harbor, ME
21. D.E. Harrison, and J.W. Doubleday Normal function of immunologic stem cells from aged mice J Immunol 114 1975 1314 1317
22. D.E. Harrison Normal function of transplanted marrow cell lines from aged mice J Gerontol 30 1975 279 285
23. D.E. Harrison, C.M. Astle, and J.W. Doubleday Cell lines from old immunodeficient donors give normal responses in young recipients J Immunol 118 1977 1223 1227
24. D.E. Harrison, C.M. Astle, and J.A. Delaittre Loss of proliferative capacity in immunohemopoietic stem cells caused by serial transplantation rather than aging J Exp Med 147 1978 1526 1531
25. D.E. Harrison Mouse erythropoietic stem cell lines function normally 100 months: loss related to number of transplantations Mech Ageing Dev 9 5-6 1979 427 433
26. D.E. Harrison Lifespans of immunohemopoietic stem cell lines Adv Pathobiol 7 1980 187 199
27. D.E. Harrison Long-term erythropoietic repopulating ability of old, young, and fetal stem cells J Exp Med 157 5 1983 1496 1504
28. G. Van Zant, P.W. Eldridge, R.R. Behringer, and M.J. Dewey Genetic control of hematopoietic kinetics revealed by analyses of allophenic mice and stem cell suicide Cell 35 1983 639 645
29. G. Van Zant, B.P. Holland, P.W. Eldridge, and J.J. Chen Genotype-restricted growth and aging patterns in hematopoietic stem cell populations of allophenic mice J Exp Med 171 1990 1547 1565
30. G. Van Zant, J.J. Chen, and K. Scott-Micus Developmental potential of hematopoietic stem cells determined using retrovirally marked allophenic marrow Blood 77 1991 756 763
31. G. Van Zant, B.P. Thompson, and J.J. Chen Differentiation of chimeric bone marrow in vivo reveals genotype-restricted contributions to hematopoiesis Exp Hematol 19 1991 941 949
32. G. Van Zant, K. Scott Micus, B.P. Thompson, R.A. Fleischman, and S. Perkins Stem cell quiescence/activation is reversible by serial transplantation and is independent of stromal cell genotype in mouse aggregation chimeras Exp Hematol 20 4 1992 470 475
33. G. de Haan, and G. Van Zant Intrinsic and extrinsic control of hemopoietic stem cell numbers: mapping of a stem cell gene J Exp Med 186 4 1997 529 536
34. G. de Haan, W. Nijhof, and G. Van Zant Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity Blood 89 5 1997 1543 1550
35. G. de Haan, S.J. Szilvassy, T.E. Meyerrose, B. Dontje, B. Grimes, and G. Van Zant Distinct functional properties of highly purified hematopoietic stem cells from mouse strains differing in stem cell numbers Blood 96 2000 1374 1379
36. G. de Haan, L.V. Bystrykh, and E. Weersing A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover Blood 100 2002 2056 2062
37. H.C. Hsu, J.D. Mountz, and R.W. Williams Age-related change in thymic T-cell development is associated with genetic loci on mouse chromosomes 1, 3, and 11 Mech Ageing Dev 123 2002 1145 1158
38. J. Chen, C.M. Astle, and D.E. Harrison Genetic regulation of primitive hematopoietic stem cell senescence Exp Hematol 28 2000 442 450
39. I.R. Lemischka, D.H. Raulet, and R.C. Mulligan Developmental potential and dynamic behavior of hematopoietic stem cells Cell 45 1986 917 927
40. N. Drize, J.R. Keller, and J. Chertkov Local clonal analysis of the hematopoietic system shows that multiple small short-living clones maintain life-long hematopoiesis in reconstituted mice Blood 88 1996 2927 2938
41. N. Drize, J. Chertkov, E. Sadovnikova, S. Tiessen, and A. Zander Long-term maintenance of hematopoiesis in irradiated mice by retrovirally transduced peripheral blood stem cells Blood 89 1997 1811 1817
42. N.J. Drize, Y.V. Olshanskaya, and L.P. Gerasimova Lifelong hematopoiesis in both reconstituted and sublethally irradiated mice is provided by multiple sequentially recruited stem cells Exp Hematol 29 2001 786 794
43. C.T. Jordan, and I.R. Lemischka Clonal and systemic analysis of long-term hematopoiesis in the mouse Gene Dev 4 1990 220 232
44. C.M. Simonaro, E.H. Schuchman, and M.E. Haskins Autologous transplantation of retrovirally transduced bone marrow or neonatal blood cells into cats can lead to long-term engraftment in the absence of myeloablation Gene Ther 6 1 1999 107 113
45. M. Schmidt, P. Zickler, and G. Hoffmann Polyclonal long-term repopulating stem cell clones in a primate model Blood 100 8 2002 2737 2743
46. + cells marked with a RD114 pseudotyped oncoretroviral vector Blood Cells Mol Dis 30 1 2003 132 143
47. K. Kuramoto, D.A. Follmann, and P. Hematti Effect of chronic cytokine therapy on clonal dynamics in non-human primates Blood 103 11 2004 4070 4077
48. K.M. Josten, J.A. Tooze, C. Borthwick-Clarke, E.C. Gordon-Smith, and T.R. Rutherford Acquired aplastic anemia and paroxysmal nocturnal hemoglobinuria: studies on clonality Blood 78 12 1991 3162 3167
49. J.P. Maciejewski, E.M. Sloand, T. Sato, S. Anderson, and N.S. Young Impaired hematopoiesis in paroxysmal nocturnal hemoglobinuria/aplastic anemia is not associated with a selective proliferative defect in the glycosylphosphatidylinositol-anchored protein-deficient clone Blood 89 4 1997 1173 1181
50. G. Chen, M. Kirby, W. Zeng, N.S. Young, and J.P. Maciejewski Superior growth of glycophosphatidylinositol-anchored protein-deficient progenitor cells in vitro is due to the higher apoptotic rate of progenitors with normal phenotype in vivo Exp Hematol 30 7 2002 774 782
51. P.J. Quesenberry, G.A. Colvin, and J.F. Lambert The chiaroscuro stem cell: a unified stem cell theory Blood 100 13 2002 4266 4271
52. + cells Exp Hematol 26 4 1998 353 360
53. E.D. Zanjani, G. Almeida-Porada, A.G. Livingston, H. Zeng, and M. Ogawa Reversible expression of CD34 by adult human bone marrow long-term engrafting hematopoietic stem cells Exp Hematol 31 5 2003 406 412
54. J. Chen, C.M. Astle, and D.E. Harrison Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction Exp Hematol 31 2003 1097 1103
55. S.J. Morrison, K.R. Prowse, P. Ho, and I.L. Weissman Telomerase activity in hematopoietic cells is associated with self-renewal potential Immunity 5 1996 207 216
56. N. Awaya, G.M. Baerlocher, and T.J. Manley Telomere shortening in hematopoietic stem cell transplantation: a potential mechanism for late graft failure Biol Blood Marrow Transplant 8 2002 597 600
57. T.H. Brummendorf, N. Rufer, and T.L. Holyoake Telomere length dynamics in normal individuals and in patients with hematopoietic stem cell-associated disorders Ann N Y Acad Sci 938 2001 293 303
58. T.H. Brummendorf, J.P. Maciejewski, J. Mak, N.S. Young, and P.M. Lansdorp Telomere length in leukocyte subpopulations of patients with aplastic anemia Blood 97 2001 895 900
59. T.H. Brummendorf, J. Mak, K.M. Sabo, G.M. Baerlocher, J.L. Abkowitz, and P.M. Lansdorp Longitudinal studies of telomere length in feline blood cells: implications for hematopoietic stem cell turnover in vivo Exp Hematol 30 10 2002 1147 1152
60. M.T. Hemann, M.A. Strong, L.Y. Hao, and C.W. Greider The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability Cell 107 2001 67 77
61. E. Samper, P. Fernandez, R. Eguia, L. Martin-Rivera, and A. Bernad Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells Blood 99 2002 2767 2775
62. R.C. Allsopp, G.B. Morin, R. DePinho, C.B. Harley, and I.L. Weissman Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation Blood 102 2003 517 520
63. E.L. Manning, J. Crossland, M.J. Dewey, and G. Van Zant Influences of inbreeding and genetics on telomere length in mice Mamm Genome 13 2002 234 238
64. G.M. Baerlocher, A. Roth, and P.M. Lansdorp Telomeres in hematopoietic stem cells Ann N Y Acad Sci 996 2003 44 48
65. J.A. Van Ziffle, G.M. Baerlocher, and P.M. Lansdorp Telomere length in subpopulations of human hematopoietic cells Stem Cells 21 2003 654 660
66. U.M. Martens, E.A. Chavez, S.S. Poon, C. Schmoor, and P.M. Lansdorp Accumulation of short telomeres in human fibroblasts prior to replicative senescence Exp Cell Res 256 2000 291 299
67. + cells from bone marrow Exp Hematol 28 9 2000 1071 1079
68. H. Geiger, S.J. Szilvassy, P. Ragland, and G. Van Zant Genetic analysis of progenitor cell mobilization by granulocyte colony-stimulating factor: verification and mechanisms for loci on murine chromosomes 2 and 11 Exp Hematol 32 1 2004 60 67
69. G. de Haan, and G. Van Zant Dynamic changes in mouse hematopoietic stem cell numbers during aging Blood 93 1999 3294 3301
70. C.D. Helgason, J. Antonchuk, C. Bodner, and R.K. Humphries Homeostasis and regeneration of the hematopoietic stem cell pool are altered in SHIP-deficient mice Blood 102 10 2003 3541 3547
71. A. Meng, Y. Wang, G. Van Zant, and D. Zhou Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells Cancer Res 63 17 2003 5414 5419
72. A. Krtolica, and J. Campisi Integrating epithelial cancer, aging stroma and cellular senescence Adv Gerontol 11 2003 109 116
73. L. Pang, P.V. Reddy, C.I. McAuliffe, G. Colvin, and P.J. Quesenberry Studies on BrdU labeling of hematopoietic cells: stem cells and cell lines J Cell Physiol 197 2 2003 251 260