Total glucosides of paeony attenuated functional maturation of dendritic cells via blocking TLR4/5 signaling in vivo

International Immunopharmacology

Volumn 14, Issue 3, 2012, Pages 275-282

  Zhou, Zhou ^a   Lin, Jinpiao ^a   Huo, Rongfen ^a   Huang, Wenkang ^a   Zhang, Jian ^a   Wang, Li ^a   Sun, Yue ^a   Shen, Baihua ^a   Li, Ningli ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Dendritic cells; Maturation; Toll like receptors; Total glucosides of paeony

Indexed keywords

INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; OVALBUMIN; PAEONIA LACTIFLORA EXTRACT; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOTAL GLUCOSIDE OF PAEONY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; OTITIS; PAEONIA LACTIFLORA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TREATMENT DURATION;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; FEMALE; GLUCOSIDES; LYMPH NODES; MICE; MICE, INBRED C57BL; OVALBUMIN; PAEONIA; PLANT EXTRACTS; PLANT ROOTS; SPLEEN; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 5;

EID: 84865285939     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.07.012     Document Type: Article

References (40)

1. D. Dudziak, A.O. Kamphorst, and G.F. Heidkamp Differential antigen processing by dendritic cell subsets in vivo Science 315 2007 107 111
2. P.M. Dominguez, and C. Ardavin Differentiation and function of mouse monocyte-derived dendritic cells in steady state and inflammation Immunol Rev 234 2010 90 104
3. J. Banchereau, and R.M. Steinman Dendritic cells and the control of immunity Nature 392 1998 245 252
4. K. Liu, G.D. Victora, and T.A. Schwickert In vivo analysis of dendritic cell development and homeostasis Science 324 2009 392 397
5. K. Liu, and M.C. Nussenzweig Origin and development of dendritic cells Immunol Rev 234 2010 45 54
6. T. Kawai, and S. Akira TLR signaling Cell Death Differ 13 2006 816 825
7. P. Tailor, T. Tamura, and K. Ozato IRF family proteins and type I interferon induction in dendritic cells Cell Res 16 2006 134 140
8. S. Janssens, and R. Beyaert A universal role for MyD88 in TLR/IL-1R-mediated signaling Trends Biochem Sci 27 2002 474 482
9. I. Zanoni, and F. Granucci Regulation of antigen uptake, migration, and lifespan of dendritic cell by Toll-like receptors J Mol Med (Berl) 88 2010 873 880
10. C. Watts, M.A. West, and R. Zaru TLR signalling regulated antigen presentation in dendritic cells Curr Opin Immunol 22 2010 124 130
11. W. Cao, W. Zhang, and J. Liu Paeoniflorin improves survival in LPS-challenged mice through the suppression of TNF-alpha and IL-1beta release and augmentation of IL-10 production Int Immunopharmacol 11 2011 172 178
12. H. Huang, E.J. Chang, and Y. Lee A genome-wide microarray analysis reveals anti-inflammatory target genes of paeonol in macrophages Inflamm Res 57 2008 189 198
13. L.L. Zhang, W. Wei, and N.P. Wang Paeoniflorin suppresses inflammatory mediator production and regulates G protein-coupled signaling in fibroblast-like synoviocytes of collagen induced arthritic rats Inflamm Res 57 2008 388 395
14. W. Zhang, and S.M. Dai Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis Int Immunopharmacol 14 2012 27 31
15. M. Zhao, G.P. Liang, and M.N. Tang Total glucosides of paeony induces regulatory CD4(+)CD25(+) T cells by increasing Foxp3 demethylation in lupus CD4(+) T cells Clin Immunol 143 2012 180 187
16. L. Wang, J. Lin, and Z. Zhou Up-regulation of Th17 cells may underlie inhibition of Treg development caused by immunization with activated syngeneic T cells PLoS One 6 2011 e27289
17. Y. Chang, W. Wei, L. Zhang, and H.M. Xu Effects and mechanisms of total glucosides of paeony on synoviocytes activities in rat collagen-induced arthritis J Ethnopharmacol 121 2009 43 48
18. J. Li, C.X. Chen, and Y.H. Shen Effects of total glucosides from paeony (Paeonia lactiflora Pall) roots on experimental atherosclerosis in rats J Ethnopharmacol 135 2011 469 475
19. H. Wu, W. Wei, and L. Song Paeoniflorin induced immune tolerance of mesenteric lymph node lymphocytes via enhancing beta 2-adrenergic receptor desensitization in rats with adjuvant arthritis Int Immunopharmacol 7 2007 662 673
20. Q. Zhang, J. Wu, and Q. Cao A critical role of Cyr61 in interleukin-17-dependent proliferation of fibroblast-like synoviocytes in rheumatoid arthritis Arthritis Rheum 60 2009 3602 3612
21. J.H. Du, and B.D. Dong Comparative study on clinical efficacy of using methotrexate singly or combined with total glucosides of Paeony in treating rheumatoid arthritis Zhongguo Zhong Xi Yi Jie He Za Zhi 25 2005 540 542
22. L. Zhu, W. Wei, Y.Q. Zheng, and X.Y. Jia Effects and mechanisms of total glucosides of paeony on joint damage in rat collagen-induced arthritis Inflamm Res 54 2005 211 220
23. P.P. Li, D.D. Liu, and Y.J. Liu BAFF/BAFF-R involved in antibodies production of rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of Paeoniflorin J Ethnopharmacol 141 2012 290 300
24. J.M. Kim, S.H. Ho, and E.J. Park Angiostatin gene transfer as an effective treatment strategy in murine collagen-induced arthritis Arthritis Rheum 46 2002 793 801
25. A.L. Smith, and M.E. Wikstrom Visualizing T cell competition for peptide/MHC complexes: a specific mechanism to minimize the effect of precursor frequency Immunity 13 2000 783 794
26. D. Matusevicius, P. Kivisakk, and B. He Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis Mult Scler 5 1999 101 104
27. N. Cools, P. Ponsaerts, V.F. Van Tendeloo, and Z.N. Berneman Balancing between immunity and tolerance: an interplay between dendritic cells, regulatory T cells, and effector T cells J Leukoc Biol 82 2007 1365 1374
28. P. Tissieres, and J. Pugin The role of MD-2 in the opsonophagocytosis of Gram-negative bacteria Curr Opin Infect Dis 22 2009 286 291
29. B.S. Park, D.H. Song, and H.M. Kim The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex Nature 458 2009 1191 1195
30. P. Gray, J. Dagvadorj, and K.S. Michelsen Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway J Immunol 187 2011 4331 4337
31. K. Kawasaki, H. Nogawa, and M. Nishijima Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 by alanine-scanning mutagenesis J Immunol 170 2003 413 420
32. U. Ohto, K. Fukase, K. Miyake, and Y. Satow Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa Science 316 2007 1632 1634
33. E.F. Kenny, and L.A. O'Neill Signalling adaptors used by Toll-like receptors: an update Cytokine 43 2008 342 349
34. S.H. Rhee, H. Kim, M.P. Moyer, and C. Pothoulakis Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells J Biol Chem 281 2006 18560 18568
35. S.M. Ivison, N.R. Graham, and C.Q. Bernales Protein kinase D interaction with TLR5 is required for inflammatory signaling in response to bacterial flagellin J Immunol 178 2007 5735 5743
36. F. Sierro, B. Dubois, and A. Coste Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells Proc Natl Acad Sci U S A 98 2001 13722 13727
37. B. Beutler Inferences, questions and possibilities in Toll-like receptor signalling Nature 430 2004 257 263
38. C. Wang, L. Deng, and M. Hong TAK1 is a ubiquitin-dependent kinase of MKK and IKK Nature 412 2001 346 351
39. K.A. Lord, B. Hoffman-Liebermann, and D.A. Liebermann Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6 Oncogene 5 1990 1095 1097
40. K.A. Lord, B. Hoffman-Liebermann, and D.A. Liebermann Complexity of the immediate early response of myeloid cells to terminal differentiation and growth arrest includes ICAM-1, Jun-B and histone variants Oncogene 5 1990 387 396