Visualizing T cell competition for peptide/MHC complexes: A specific mechanism to minimize the effect of precursor frequency

Immunity

Volumn 13, Issue 6, 2000, Pages 783-794

  Smith, A L ^a   Wikstrom, M E ^a   Fazekas de St Groth, B ^a  

^a CENTENARY INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN; PEPTIDE MBP; PEPTIDE MCC; SYNTHETIC PEPTIDE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; BINDING COMPETITION; CELL DIVISION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; IMMUNOREGULATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; STEM CELL; T LYMPHOCYTE ACTIVATION;

EID: 0034502221     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)00076-5     Document Type: Article

References (34)

1. Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
2. Hierarchy in the ability of T cell epitopes to induce peripheral tolerance to antigens from myelin
3. Functional analysis of the interaction of the antigen-specific T cell receptor with its ligands
4. Use of a receptor competition assay to explore the interaction of the T cell antigen-specific receptor with its ligands
5. Helper T cell differentiation is controlled by the cell cycle
6. T cell affinity maturation by selective expansion during infection
7. + T cells during an acute virus infection
8. Influence of B cell receptor ligation and TCR affinity on T-B collaboration in vitro
9. An analysis of T cell receptor-ligand interaction using a transgenic antigen model for T cell tolerance and T cell receptor mutagenesis
10. The evolution of self tolerance: A new cell is required to meet the challenge of self-reactivity
11. CFSE and the virgin lymphocyte: A marriage made in heaven
12. The fate of self-reactive B-cells depends primarily on the degree of antigen receptor engagement and availability of T-cell help
13. Cell division regulates the T cell cytokine repertoire revealing a mechanism underlying immune class regulation
14. The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model
15. + T cells in transgenic mice expressing a class II MHC restricted antigen receptor
16. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
17. + T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4
18. T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides
19. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice
20. MHC multimerization, antigen expression and the induction of APC amnesia in the developing immune response
21. Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen
22. Stimulation with specific antigen can block superantigen-mediated deletion of T cells in vivo
23. H compartment
24. Evolution of antigen-specific T cell receptors in vivo: Preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs
25. Antigen-specific development of primary and memory T cells in vivo
26. + T cells
27. Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
28. + T cell responses in vivo and in vitro
29. A kinetic basis for T cell receptor repertoire selection during an immune response
30. + dendritic cells generate an immune response without homing to the draining lymph node
31. Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor
32. Serial triggering of many T-cell receptors by a few peptide-MHC complexes
33. Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity
34. Locus-specific somatic hypermutation in germinal centre T cells