-
1
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H,. Wnt/beta-catenin signaling in development and disease. Cell. 2006; 127: 469-80.
-
(2006)
Cell.
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
2
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X,. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell. 2009; 17: 9-26.
-
(2009)
Dev Cell.
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
3
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
Logan CY, Nusse R,. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol. 2004; 20: 781-10.
-
(2004)
Annu Rev Cell Dev Biol.
, vol.20
, pp. 781-710
-
-
Logan, C.Y.1
Nusse, R.2
-
4
-
-
33846193290
-
The many ways of Wnt in cancer
-
DOI 10.1016/j.gde.2006.12.007, PII S0959437X06002413, Genetic and Cellular mechanisms of oncogenesis
-
Polakis P,. The many ways of Wnt in cancer. Curr Opin Genet Dev. 2007; 17: 45-51. (Pubitemid 46109296)
-
(2007)
Current Opinion in Genetics and Development
, vol.17
, Issue.1
, pp. 45-51
-
-
Polakis, P.1
-
5
-
-
18044386744
-
LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
-
DOI 10.1016/S0092-8674(01)00571-2
-
Gong Y, Slee RB, Fukai N, Rawadi G, Roman-Roman S, Reginato AM, Wang H, Cundy T, Glorieux FH, Lev D, Zacharin M, Oexle K, Marcelino J, Suwairi W, Heeger S, Sabatakos G, Apte S, Adkins WN, Allgrove J, Arslan-Kirchner M, Batch JA, Beighton P, Black GC, Boles RG, Boon LM, Borrone C, Brunner HG, Carle GF, Dallapiccola B, De Paepe A, Floege B, Halfhide ML, Hall B, Hennekam RC, Hirose T, Jans A, Juppner H, Kim CA, Keppler-Noreuil K, Kohlschuetter A, LaCombe D, Lambert M, Lemyre E, Letteboer T, Peltonen L, Ramesar RS, Romanengo M, Somer H, Steichen-Gersdorf E, Steinmann B, Sullivan B, Superti-Furga A, Swoboda W, van den Boogaard MJ, Van Hul W, Vikkula M, Votruba M, Zabel B, Garcia T, Baron R, Olsen BR, Warman ML,. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell. 2001; 107: 513-23. (Pubitemid 33152786)
-
(2001)
Cell
, vol.107
, Issue.4
, pp. 513-523
-
-
Gong, Y.1
Slee, R.B.2
Fukai, N.3
Rawadi, G.4
Roman-Roman, S.5
Reginato, A.M.6
Wang, H.7
Cundy, T.8
Glorieux, F.H.9
Lev, D.10
Zacharin, M.11
Oexle, K.12
Marcelino, J.13
Suwairi, W.14
Heeger, S.15
Sabatakos, G.16
Apte, S.17
Adkins, W.N.18
Allgrove, J.19
Arslan-Kirchner, M.20
Batch, J.A.21
Beighton, P.22
Black, G.C.M.23
Boles, R.G.24
Boon, L.M.25
Borrone, C.26
Brunner, H.G.27
Carle, G.F.28
Dallapiccola, B.29
De Paepe, A.30
Floege, B.31
Halfhide, M.L.32
Hall, B.33
Hennekam, R.C.34
Hirose, T.35
Jans, A.36
Juppner, H.37
Kim, C.A.38
Keppler-Noreuil, K.39
Kohlschuetter, A.40
LaCombe, D.41
Lambert, M.42
Lemyre, E.43
Letteboer, T.44
Peltonen, L.45
Ramesar, R.S.46
Romanengo, M.47
Somer, H.48
Steichen-Gersdorf, E.49
Steinmann, B.50
Sullivan, B.51
Superti-Furga, A.52
Swoboda, W.53
Van Den Boogaard, M.-J.54
Van Hul, W.55
Vikkula, M.56
Votruba, M.57
Zabel, B.58
Garcia, T.59
Baron, R.60
Olsen, B.R.61
Warman, M.L.62
more..
-
6
-
-
13844269808
-
LRP5 and Wnt signaling: A union made for bone
-
DOI 10.1359/JBMR.040816
-
Johnson ML, Harnish K, Nusse R, Van Hul W,. LRP5 and Wnt signaling: a union made for bone. J Bone Miner Res. 2004; 19: 1749-57. (Pubitemid 41103424)
-
(2004)
Journal of Bone and Mineral Research
, vol.19
, Issue.11
, pp. 1749-1757
-
-
Johnson, M.L.1
Harnish, K.2
Nusse, R.3
Van Hul, W.4
-
7
-
-
33847656105
-
LRP6 mutation in a family with early coronary disease and metabolic risk factors
-
DOI 10.1126/science.1136370
-
Mani A, Radhakrishnan J, Wang H, Mani MA, Nelson-Williams C, Carew KS, Mane S, Najmabadi H, Wu D, Lifton RP,. LRP6 mutation in a family with early coronary disease and metabolic risk factors. Science. 2007; 315: 1278-82. (Pubitemid 46364265)
-
(2007)
Science
, vol.315
, Issue.5816
, pp. 1278-1282
-
-
Mani, A.1
Radhakrishnan, J.2
Wang, H.3
Mani, A.4
Mani, M.-A.5
Nelson-Williams, C.6
Carew, K.S.7
Mane, S.8
Najmabadi, H.9
Wu, D.10
Lifton, R.P.11
-
8
-
-
18344377028
-
Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations
-
DOI 10.1038/sj.onc.1208511
-
He B, Reguart N, You L, Mazieres J, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM,. Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations. Oncogene. 2005; 24: 3054-8. (Pubitemid 40675537)
-
(2005)
Oncogene
, vol.24
, Issue.18
, pp. 3054-3058
-
-
He, B.1
Reguart, N.2
You, L.3
Mazieres, J.4
Xu, Z.5
Lee, A.Y.6
Mikami, I.7
McCormick, F.8
Jablons, D.M.9
-
9
-
-
58249122326
-
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
-
Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, Chen C, Lum L,. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol. 2009; 5: 100-7.
-
(2009)
Nat Chem Biol.
, vol.5
, pp. 100-107
-
-
Chen, B.1
Dodge, M.E.2
Tang, W.3
Lu, J.4
Ma, Z.5
Fan, C.W.6
Wei, S.7
Hao, W.8
Kilgore, J.9
Williams, N.S.10
Roth, M.G.11
Amatruda, J.F.12
Chen, C.13
Lum, L.14
-
10
-
-
62649175248
-
Inhibition of Wnt signaling by Dishevelled PDZ peptides
-
Zhang Y, Appleton BA, Wiesmann C, Lau T, Costa M, Hannoush RN, Sidhu SS,. Inhibition of Wnt signaling by Dishevelled PDZ peptides. Nat Chem Biol. 2009; 5: 217-9.
-
(2009)
Nat Chem Biol.
, vol.5
, pp. 217-219
-
-
Zhang, Y.1
Appleton, B.A.2
Wiesmann, C.3
Lau, T.4
Costa, M.5
Hannoush, R.N.6
Sidhu, S.S.7
-
11
-
-
77958171338
-
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1alpha
-
Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM 3rd, Lee E,. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1alpha. Nat Chem Biol. 6: 829-36.
-
Nat Chem Biol.
, vol.6
, pp. 829-836
-
-
Thorne, C.A.1
Hanson, A.J.2
Schneider, J.3
Tahinci, E.4
Orton, D.5
Cselenyi, C.S.6
Jernigan, K.K.7
Meyers, K.C.8
Hang, B.I.9
Waterson, A.G.10
Kim, K.11
Melancon, B.12
Ghidu, V.P.13
Sulikowski, G.A.14
Lafleur, B.15
Salic, A.16
Lee, L.A.17
Miller III, D.M.18
Lee, E.19
-
12
-
-
33845992865
-
The promise of canonical Wnt signaling modulators in enhancing bone repair
-
DOI 10.1358/dnp.2006.19.8.1043960
-
Gregory CA, Green A, Lee N, Rao A, Gunn W,. The promise of canonical Wnt signaling modulators in enhancing bone repair. Drug News Perspect. 2006; 19: 445-52. (Pubitemid 46050818)
-
(2006)
Drug News and Perspectives
, vol.19
, Issue.8
, pp. 445-452
-
-
Gregory, C.A.1
Green, A.2
Lee, N.3
Rao, A.4
Gunn, W.5
-
13
-
-
58649087137
-
Where Wnts went: The exploding field of Lrp5 and Lrp6 signaling in bone
-
Williams BO, Insogna KL,. Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone. J Bone Miner Res. 2009; 24: 171-8.
-
(2009)
J Bone Miner Res.
, vol.24
, pp. 171-178
-
-
Williams, B.O.1
Insogna, K.L.2
-
14
-
-
33646414025
-
Orally bioavailable GSK-3α/β dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo
-
DOI 10.1359/jbmr.060316
-
Kulkarni NH, Onyia JE, Zeng Q, Tian X, Liu M, Halladay DL, Frolik CA, Engler T, Wei T, Kriauciunas A, Martin TJ, Sato M, Bryant HU, Ma YL,. Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo. J Bone Miner Res. 2006; 21: 910-20. (Pubitemid 43787998)
-
(2006)
Journal of Bone and Mineral Research
, vol.21
, Issue.6
, pp. 910-920
-
-
Kulkarni, N.H.1
Onyia, J.E.2
Zeng, Q.3
Tian, X.4
Liu, M.5
Halladay, D.L.6
Frolik, C.A.7
Engler, T.8
Wei, T.9
Kriauciunas, A.10
Martin, T.J.11
Sato, M.12
Bryant, H.U.13
Ma, Y.L.14
-
15
-
-
28444438846
-
Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice
-
DOI 10.1073/pnas.0505259102
-
Clement-Lacroix P, Ai M, Morvan F, Roman-Roman S, Vayssiere B, Belleville C, Estrera K, Warman ML, Baron R, Rawadi G,. Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice. Proc Natl Acad Sci USA. 2005; 102: 17406-11. (Pubitemid 41740879)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.48
, pp. 17406-17411
-
-
Clement-Lacroix, P.1
Ai, M.2
Morvan, F.3
Roman-Roman, S.4
Vayssiere, B.5
Belleville, C.6
Estrera, K.7
Warman, M.L.8
Baron, R.9
Rawadi, G.10
-
16
-
-
78650040987
-
Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo
-
Glantschnig H, Hampton RA, Lu P, Zhao JZ, Vitelli S, Huang L, Haytko P, Cusick T, Ireland C, Jarantow SW, Ernst R, Wei N, Nantermet P, Scott KR, Fisher JE, Talamo F, Orsatti L, Reszka AA, Sandhu P, Kimmel D, Flores O, Strohl W, An Z, Wang F,. Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo. J Biol Chem. 285: 40135-47.
-
J Biol Chem.
, vol.285
, pp. 40135-40147
-
-
Glantschnig, H.1
Hampton, R.A.2
Lu, P.3
Zhao, J.Z.4
Vitelli, S.5
Huang, L.6
Haytko, P.7
Cusick, T.8
Ireland, C.9
Jarantow, S.W.10
Ernst, R.11
Wei, N.12
Nantermet, P.13
Scott, K.R.14
Fisher, J.E.15
Talamo, F.16
Orsatti, L.17
Reszka, A.A.18
Sandhu, P.19
Kimmel, D.20
Flores, O.21
Strohl, W.22
An, Z.23
Wang, F.24
more..
-
17
-
-
67349126564
-
A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation
-
Bodine PV, Stauffer B, Ponce-de-Leon H, Bhat RA, Mangine A, Seestaller-Wehr LM, Moran RA, Billiard J, Fukayama S, Komm BS, Pitts K, Krishnamurthy G, Gopalsamy A, Shi M, Kern JC, Commons TJ, Woodworth RP, Wilson MA, Welmaker GS, Trybulski EJ, Moore WJ,. A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation. Bone. 2009; 44: 1063-8.
-
(2009)
Bone.
, vol.44
, pp. 1063-1068
-
-
Bodine, P.V.1
Stauffer, B.2
Ponce-De-Leon, H.3
Bhat, R.A.4
Mangine, A.5
Seestaller-Wehr, L.M.6
Moran, R.A.7
Billiard, J.8
Fukayama, S.9
Komm, B.S.10
Pitts, K.11
Krishnamurthy, G.12
Gopalsamy, A.13
Shi, M.14
Kern, J.C.15
Commons, T.J.16
Woodworth, R.P.17
Wilson, M.A.18
Welmaker, G.S.19
Trybulski, E.J.20
Moore, W.J.21
more..
-
18
-
-
85080838364
-
Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats
-
Li X, Warmington KS, Niu QT, Asuncion FJ, Barrero M, Grisanti M, Dwyer D, Stouch B, Thway TM, Stolina M, Ominsky MS, Kostenuik PJ, Simonet WS, Paszty C, Ke HZ,. Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats. J Bone Miner Res. 25: 2371-80.
-
J Bone Miner Res.
, vol.25
, pp. 2371-2380
-
-
Li, X.1
Warmington, K.S.2
Niu, Q.T.3
Asuncion, F.J.4
Barrero, M.5
Grisanti, M.6
Dwyer, D.7
Stouch, B.8
Thway, T.M.9
Stolina, M.10
Ominsky, M.S.11
Kostenuik, P.J.12
Simonet, W.S.13
Paszty, C.14
Ke, H.Z.15
-
19
-
-
1542347695
-
Convergence of Wnt, β-Catenin, and Cadherin pathways
-
DOI 10.1126/science.1094291
-
Nelson WJ, Nusse R,. Convergence of Wnt, beta-catenin, and cadherin pathways. Science. 2004; 303: 1483-7. (Pubitemid 38314410)
-
(2004)
Science
, vol.303
, Issue.5663
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
20
-
-
59449095748
-
N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation
-
Haÿ E, Laplantine E, Geoffroy V, Frain M, Kohler T, Muller R, Marie PJ,. N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation. Mol Cell Biol. 2009; 29: 953-64.
-
(2009)
Mol Cell Biol.
, vol.29
, pp. 953-964
-
-
Haÿ, E.1
Laplantine, E.2
Geoffroy, V.3
Frain, M.4
Kohler, T.5
Muller, R.6
Marie, P.J.7
-
21
-
-
17044462159
-
Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway
-
DOI 10.1074/jbc.M411999200
-
Haÿ E, Faucheu C, Suc-Royer I, Touitou R, Stiot V, Vayssiere B, Baron R, Roman-Roman S, Rawadi G,. Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway. J Biol Chem. 2005; 280: 13616-23. (Pubitemid 40517255)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.14
, pp. 13616-13623
-
-
Hay, E.1
Faucheu, C.2
Suc-Royer, I.3
Touitou, R.4
Stiot, V.5
Vayssiere, B.6
Baron, R.7
Roman-Roman, S.8
Rawadi, G.9
-
22
-
-
77954069774
-
N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling
-
Haÿ E, Nouraud A, Marie PJ,. N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling. PLoS One. 2009; 4: e8284.
-
(2009)
PLoS One.
, vol.4
-
-
Haÿ, E.1
Nouraud, A.2
Marie, P.J.3
-
23
-
-
0035800764
-
Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway
-
Haÿ E, Lemonnier J, Fromigue O, Marie PJ,. Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway. J Biol Chem. 2001; 276: 29028-36.
-
(2001)
J Biol Chem.
, vol.276
, pp. 29028-29036
-
-
Haÿ, E.1
Lemonnier, J.2
Fromigue, O.3
Marie, P.J.4
-
24
-
-
34447526757
-
Novel LRP5 missense mutation in a patient with a high bone mass phenotype results in decreased DKK1-mediated inhibition of Wnt signaling
-
DOI 10.1359/jbmr.070211
-
Balemans W, Devogelaer JP, Cleiren E, Piters E, Caussin E, Van Hul W,. Novel LRP5 missense mutation in a patient with a high bone mass phenotype results in decreased DKK1-mediated inhibition of Wnt signaling. J Bone Miner Res. 2007; 22: 708-16. (Pubitemid 351339099)
-
(2007)
Journal of Bone and Mineral Research
, vol.22
, Issue.5
, pp. 708-716
-
-
Balemans, W.1
Devogelaer, J.-P.2
Cleiren, E.3
Piters, E.4
Caussin, E.5
Van Hul, W.6
-
25
-
-
38949194936
-
Initiation of Wnt signaling: Control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
-
DOI 10.1242/dev.013540
-
Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, He X,. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development. 2008; 135: 367-75. (Pubitemid 351228428)
-
(2008)
Development
, vol.135
, Issue.2
, pp. 367-375
-
-
Zeng, X.1
Huang, H.2
Tamai, K.3
Zhang, X.4
Harada, Y.5
Yokota, C.6
Almeida, K.7
Wang, J.8
Doble, B.9
Woodgett, J.10
Wynshaw-Boris, A.11
Hsieh, J.-C.12
He, X.13
-
26
-
-
33845987376
-
Networks and hubs for the transcriptional control of osteoblastogenesis
-
DOI 10.1007/s11154-006-9001-5, Special Issue on Osteoporosis
-
Lian JB, Stein GS, Javed A, van Wijnen AJ, Stein JL, Montecino M, Hassan MQ, Gaur T, Lengner CJ, Young DW,. Networks and hubs for the transcriptional control of osteoblastogenesis. Rev Endocr Metab Disord. 2006; 7: 1-16. (Pubitemid 46044345)
-
(2006)
Reviews in Endocrine and Metabolic Disorders
, vol.7
, Issue.1-2
, pp. 1-16
-
-
Lian, J.B.1
Stein, G.S.2
Javed, A.3
Van Wijnen, A.J.4
Stein, J.L.5
Montecino, M.6
Hassan, M.Q.7
Gaur, T.8
Lengner, C.J.9
Young, D.W.10
-
27
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
-
DOI 10.1016/S1097-2765(01)00224-6
-
Mao J, Wang J, Liu B, Pan W, Farr GH 3rd, Flynn C, Yuan H, Takada S, Kimelman D, Li L, Wu D,. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell. 2001; 7: 801-9. (Pubitemid 32436440)
-
(2001)
Molecular Cell
, vol.7
, Issue.4
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
Pan, W.4
Farr III, G.H.5
Flynn, C.6
Yuan, H.7
Takada, S.8
Kimelman, D.9
Li, L.10
Wu, D.11
-
29
-
-
0036158227
-
Role of N-Cadherin in bone formation
-
DOI 10.1002/jcp.10073
-
Marie PJ,. Role of N-cadherin in bone formation. J Cell Physiol. 2002; 190: 297-305. (Pubitemid 34111970)
-
(2002)
Journal of Cellular Physiology
, vol.190
, Issue.3
, pp. 297-305
-
-
Marie, P.J.1
-
30
-
-
33845227116
-
Cell-cell adhesion and signaling through cadherins: Connecting bone cells in their microenvironment
-
DOI 10.1359/jbmr.060811
-
Mbalaviele G, Shin CS, Civitelli R,. Cell-cell adhesion and signaling through cadherins: connecting bone cells in their microenvironment. J Bone Miner Res. 2006; 21: 1821-7. (Pubitemid 44851556)
-
(2006)
Journal of Bone and Mineral Research
, vol.21
, Issue.12
, pp. 1821-1827
-
-
Mbalaviele, G.1
Chan, S.S.2
Civitelli, R.3
-
31
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
DOI 10.1038/nature03319
-
Reya T, Clevers H,. Wnt signalling in stem cells and cancer. Nature. 2005; 434: 843-50. (Pubitemid 40558990)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
32
-
-
29244446792
-
Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblast by β-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT
-
DOI 10.1074/jbc.M502168200
-
Almeida M, Han L, Bellido T, Manolagas SC, Kousteni S,. Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT. J Biol Chem. 2005; 280: 41342-51. (Pubitemid 41832191)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.50
, pp. 41342-41351
-
-
Almeida, M.1
Han, L.2
Bellido, T.3
Manolagas, S.C.4
Kousteni, S.5
-
33
-
-
0033521078
-
Stimulation of bone formation in vitro and in rodents by statins
-
Mundy G, Garrett R, Harris S, Chan J, Chen D, Rossini G, Boyce B, Zhao M, Gutierrez G,. Stimulation of bone formation in vitro and in rodents by statins. Science. 1999; 286: 1946-9. (Pubitemid 129515901)
-
(1999)
Science
, vol.286
, Issue.5446
, pp. 1946-1949
-
-
Mundy, G.1
Garrett, R.2
Harris, S.3
Chan, J.4
Chen, D.5
Rossini, G.6
Boyce, B.7
Zhao, M.8
Gutierrez, G.9
-
34
-
-
70649094222
-
BMP2 signaling in bone development and repair
-
Rosen V,. BMP2 signaling in bone development and repair. Cytokine Growth Factor Rev. 2009; 20: 475-80.
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 475-480
-
-
Rosen, V.1
-
35
-
-
0035853847
-
The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover
-
Huber AH, Stewart DB, Laurents DV, Nelson WJ, Weis WI,. The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover. J Biol Chem. 2001; 276: 12301-9.
-
(2001)
J Biol Chem.
, vol.276
, pp. 12301-12309
-
-
Huber, A.H.1
Stewart, D.B.2
Laurents, D.V.3
Nelson, W.J.4
Weis, W.I.5
-
36
-
-
79951963618
-
Adhesion molecule signalling: Not always a sticky business
-
Cavallaro U, Dejana E,. Adhesion molecule signalling: not always a sticky business. Nat Rev Mol Cell Biol. 12: 189-97.
-
Nat Rev Mol Cell Biol.
, vol.12
, pp. 189-197
-
-
Cavallaro, U.1
Dejana, E.2
-
37
-
-
0037205007
-
The promise and perils of Wnt signaling through β-catenin
-
DOI 10.1126/science.1071549
-
Moon RT, Bowerman B, Boutros M, Perrimon N,. The promise and perils of Wnt signaling through beta-catenin. Science. 2002; 296: 1644-6. (Pubitemid 34579151)
-
(2002)
Science
, vol.296
, Issue.5573
, pp. 1644-1646
-
-
Moon, R.T.1
Bowerman, B.2
Boutros, M.3
Perrimon, N.4
-
38
-
-
33751530490
-
Mining the Wnt pathway for cancer therapeutics
-
DOI 10.1038/nrd2154, PII NRD2154
-
Barker N, Clevers H,. Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov. 2006; 5: 997-1014. (Pubitemid 44835127)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.12
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
39
-
-
79952599578
-
Senescence-associated intrinsic mechanisms of osteoblast dysfunctions
-
Kassem M, Marie PJ,. Senescence-associated intrinsic mechanisms of osteoblast dysfunctions. Aging Cell. 2011; 10: 191-7.
-
(2011)
Aging Cell.
, vol.10
, pp. 191-197
-
-
Kassem, M.1
Marie, P.J.2
-
40
-
-
0034103380
-
Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: Antagonism by noggin
-
Abe E, Yamamoto M, Taguchi Y, Lecka-Czernik B, O'Brien CA, Economides AN, Stahl N, Jilka RL, Manolagas SC,. Essential requirement of BMPs-2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin. J Bone Miner Res. 2000; 15: 663-73. (Pubitemid 30174020)
-
(2000)
Journal of Bone and Mineral Research
, vol.15
, Issue.4
, pp. 663-673
-
-
Abe, E.1
Yamamoto, M.2
Taguchi, Y.3
Lecka-Czernik, B.4
O'Brien, C.A.5
Economides, A.N.6
Stahl, N.7
Jilka, R.L.8
Manolagas, S.C.9
|