Pten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects

Development (Cambridge)

Volumn 139, Issue 18, 2012, Pages 3422-3431

  Zhu, Guo ^a,b   Chow, Lionel M L ^a,c   Bayazitov, Ildar T ^a   Tong, Yiai ^a   Gilbertson, Richard J ^a   Zakharenko, Stanislav S ^a   Solecki, David J ^a   Baker, Suzanne J ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Differentiation; Migration; Mouse; mTOR PI3K; Neuroblast; Pten

Indexed keywords

ALKALINE PHOSPHATASE; CASPASE 3; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOACCUMULATION; BRAIN DEVELOPMENT; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SUBPOPULATION; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INHIBITION KINETICS; INTERNAL RIBOSOME ENTRY SITE; INTRON; MOLECULAR DYNAMICS; MOUSE; NERVE CELL DIFFERENTIATION; NEUROBLAST; NONHUMAN; OLFACTORY BULB; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBVENTRICULAR ZONE;

ANIMALS; BRAIN; CELL DIFFERENTIATION; CELL MOVEMENT; ELECTROPORATION; MICE; MICE, TRANSGENIC; NEURONS; PROTEINS; PTEN PHOSPHOHYDROLASE;

EID: 84865217428     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.083154     Document Type: Article

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