Protective effect of deferricoprogen isolated from monascus purpureus NTU 568 on citrinin-induced apoptosis in HEK-293 cells

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 32, 2012, Pages 7880-7885

  Hsu, Li Chuan ^a,b   Hsu, Ya Wen ^a,b   Liang, Yu Han ^a,b   Lin, Zhi Hu ^b   Kuo, Yao Haur ^b,c   Pan, Tzu Ming ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Citrinin; deferricoprogen; HEK 293 cells; Monascus purpureus; nephrotoxicity

Indexed keywords

CITRININ; DEFERRICOPROGEN; HEK293 CELLS; MONASCUS PURPUREUS; NEPHROTOXICITY;

ASSAYS; BROMINE COMPOUNDS; MASS SPECTROMETRY;

CELL DEATH;

ANTIOXIDANT; CASPASE; CITRININ; DEFERRICOPROGEN; HYDROXAMIC ACID; PIPERAZINEDIONE;

APOPTOSIS; ARTICLE; CELL STRAIN HEK293; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; FERMENTATION; HUMAN; ISOLATION AND PURIFICATION; KIDNEY DISEASE; METABOLISM; MICROBIOLOGY; MONASCUS; RICE;

ANTIOXIDANTS; APOPTOSIS; CASPASES; CITRININ; DIKETOPIPERAZINES; FERMENTATION; HEK293 CELLS; HUMANS; HYDROXAMIC ACIDS; KIDNEY DISEASES; MONASCUS; ORYZA SATIVA;

EID: 84865141642     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf301889q     Document Type: Article

References (39)

1. Lee, C. L.; Tsai, T. Y.; Wang, J. J.; Pan, T. M. In vivo hypolipidemic effects and safety of low dosage Monascus powder in a hamster model of hyperlipidemia Appl. Microbiol. Biotechnol. 2006, 70, 533-540
2. Wang, J. J.; Shieh, M. J.; Kuo, S. L.; Lee, C. L.; Pan, T. M. Effect of red mold rice on antifatigue and exercise-related changes in lipid peroxidation in endurance exercise Appl. Microbiol. Biotechnol. 2006, 70, 247-253
3. Lee, C. L.; Kuo, T. F.; Wu, C. L.; Wang, J. J.; Pan, T. M. Red mold rice promotes neuroprotective sAPPalpha secretion instead of Alzheimers risk factors and amyloid beta expression in hyperlipidemic Aβ40-infused rats J. Agric. Food Chem. 2010, 58, 2230-2238
4. Lee, C. L.; Kuo, T. F.; Wang, J. J.; Pan, T. M. Red mold rice ameliorates impairment of memory and learning ability in intracerebroventricular amyloid β-infused rat by repressing amyloid β accumulation J. Neurosci. Res. 2007, 85, 3171-3182
5. Chen, W. P.; Ho, B. Y.; Lee, C. L.; Lee, C. H.; Pan, T. M. Red mold rice prevents the development of obesity, dyslipidemia and hyperinsulinemia induced by high-fat diet Int. J. Obes. 2008, 32, 1694-1704
6. Tsai, R. L.; Ho, B. Y.; Pan, T. M. Red mold rice mitigates oral carcinogenesis in 7,12-dimethyl-1,2-benz[ a ]anthracene-induced oral carcinogenesis in hamster Evidence-Based Complementary Altern. Med. 2011, 10.1093/ecam/nep215
7. 2/M arrest and apoptosis in human oral cancer cells J. Sci. Food. Agri. 2010, 90, 2709-2715
8. Ho, B. Y.; Wu, Y. M.; Hsu, Y. W.; Hsu, L. C.; Kuo, Y. H.; Chang, K. J.; Pan, T. M. Effects of Monascus -fermented rice extract on malignant cell-associated neovascularization and intravasation determined using the chicken embryo chorioallantoic membrane model Integr. Cancer Ther. 2010, 2, 204-212
9. Li, Y. G.; Zhang, F.; Wang, Z. T.; Hu, Z. B. Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass spectrometry J. Pharm. Biomed. Anal. 2004, 35, 1101-1112 (Pubitemid 39140277)
10. Tsuji, K.; Ichikawa, T.; Tanabe, N.; Obata, H.; Abe, S.; Tarui, S.; Nakagawa, Y. Extraction of hypotensive substance from wheat beni-koji J. Jpn. Soc. Food Sci. Technol. 1992, 39, 913-918
11. Wu, C. L.; Lee, C. L.; Pan, T. M. Red mold dioscorea has a greater antihypertensive effect than traditional red mold rice in spontaneously hypertensive rats J. Agric. Food Chem. 2009, 57, 5035-5041
12. Aniya, Y.; Yokomakura, T.; Yonamine, M.; Shimada, K.; Nagamine, T.; Shimabukuro, M.; Gibo, H. Screening of antioxidant action of various molds and protection of Monascus anka against experimentally induced liver injuries of rats Gen. Pharmacol. 1999, 32, 225-231 (Pubitemid 29127120)
13. Hsu, Y. W.; Hsu, L. C.; Chang, C. L.; Liang, Y. H.; Kuo, Y. H.; Pan, T. M. New anti-inflammatory and anti-proliferative constituents from fermented red mold rice Monascus purpureus NTU 568 Molecules 2010, 15, 7815-7824
14. Hsu, L. C.; Hsu, Y. W.; Liang, Y. H.; Kuo, Y. H.; Pan, T. M. Anti-tumor and anti-inflammatory properties of ankaflavin and monaphilone A from Monascus purpureus NTU 568 J. Agric. Food Chem. 2011, 59, 1124-1130
15. Ciegler, A.; Vesonder, R. F.; Jackson, L. K. Production and biological activity of patulin and citrinin from Penicillium expansum Appl. Environ. Microbiol. 1977, 33, 1004-1006 (Pubitemid 8087970)
16. Bragulat, M. R.; Martinez, E.; Castella, G.; Cabanes, F. J.; Ochratoxin, A and citrinin producing species of the genus Penicillium form feedstuffs Int. J. Food Microbiol. 2008, 126, 43-48
17. Gupta, M.; Sasmal, D.; Bandyopadhyay, S.; Bagchi, G.; Chatterjee, T.; Dey, S. Hematological changes produced in mice by ochratoxin A and citrinin Toxicology 1983, 26, 55-62 (Pubitemid 13153382)
18. Kanisawa, M. Synergistic effect of citrinin on hepatorenal carcinogenesis of ochratoxin A in mice Dev. Food Sci. 1984, 7, 245-254
19. Riveiro, S. M. R.; Chagas, G. M.; Campello, A. P.; Kluppel, L. W. Mechanism of citrinin-induced dysfunction of mitochondria. V. Effect on the homeostasis of the reactive oxygen species Cell Biochem. Funct. 1997, 15, 203-209 (Pubitemid 27395287)
20. Iwahashi, H.; Kitagawa, E.; Suzuki, Y.; Ueda, Y.; Ishizawa, Y.; Nobumasa, H.; Kuboki, Y.; Iwahashi, Y. Evaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and oligo DNA microarray BMC Genomics 2007, 8, 95-99
21. 2 cells by resveratrol Int. J. Mol. Sci. 2009, 10, 3338-3357
22. Sokmen, M.; Angelove, M.; Krumova, E.; Pashova, S.; Ivancheva, S.; Sokmen, A. In vitro antioxidant activity of polyphenol extracts with antiviral properties from Geranium sanguineum L Life Sci. 2005, 76, 2981-2993 (Pubitemid 40488302)
23. Edmondson, J. M.; Armstrong, L. S.; Martinez, A. O. A rapid and simple MTT-based spectrophotometric assay for determining drug sensitivity in monolayer cultures Methods Cell Sci. 1988, 11, 15-17
24. Morgan, D. M. Tetrazolium (MTT) assay for cellular viability and activity Methods Mol. Biol. 1998, 79, 179-183
25. Frederick, C. B.; Bentley, M. D.; Shive, W. Structure of triornicin, a new siderophore Biochemistry 1981, 20, 2436-2438
26. Hsu, Y. W.; Hsu, L. C.; Liang, Y. H.; Kuo, Y. H.; Pan, T. M. Monaphilones A-C, three new antiproliferative azaphilone derivatives from Monascus purpureus NTU 568 J. Agric. Food Chem. 2010, 58, 8211-8216
27. Hsu, L. C.; Hsu, Y. W.; Liang, Y. H.; Liaw, C. C.; Kuo, Y. H.; Pan, T. M. Induction of apoptosis in human breast adenocarcinoma cells MCF-7 by monapurpyridine A, a new azaphilone derivative from Monascus purpureus NTU 568 Molecules 2012, 17, 664-673
28. Aniya, Y.; Ohtani, I. I.; Higa, T.; Miyagi, C.; Gibo, H.; Shimabukuro, M.; Nakanish, H.; Taira, J. Dimerumic acid as an antioxidant of the mold, Monascus anka Free Radical Biol. Med. 2000, 28, 999-1004
29. Shi, Y. C.; Liao, V. H. C.; Pan, T. M. Monascin from red mold dioscorea as a novel antidiabetic and antioxidative stress agent in rats and Caenorhabditis elegans Free Radical Biol. Med. 2012, 52, 109-117
30. Chang, C. H.; Yu, F. Y.; Wang, L. T.; Lin, Y. S.; Liu, B. H. Activation of ERK and JNK signaling pathways by mycotoxin citrinin in human cells Toxicol. Appl. Pharmacol. 2009, 237, 281-287
31. Huang, Y. T.; Lai, C. Y.; Lou, S. L.; Yeh, J. M.; Chan, W. H. Activation of JNK and PAK2 is essential for citrinin-induced apoptosis in human osteoblast cell line Environ. Toxicol. 2008, 10, 343-355
32. Hengartner, M. O. The biochemistry of apoptosis Nature 2000, 407, 770-776
33. Budihardjo, I.; Oliver, H.; Lutter, M.; Luo, X.; Wang, X. Biochemical pathways of caspase activation during apoptosis Ann. Rev. Cell Dev. Biol. 1999, 15, 269-290 (Pubitemid 32250377)
34. Wang, J. J.; Lee, C. L.; Pan, T. M. Modified mutation method for screening low citrinin-producing strains of Monascus purpureus on rice culture J. Agric. Food Chem. 2004, 52, 6977-6982
35. Wang, J. J.; Pan, T. M. Improvement of monacolin K, γ-aminobutyric acid and citrinin production ratio as a function of environmental conditions of Monascus purpureus NTU 601 J. Ind. Microbiol. Biotechnol. 2003, 30, 669-676
36. Lee, C. L.; Hung, H. K.; Wang, J. J.; Pan, T. M. Improving the ratio of monacolin K to citrinin production of Monascus purpureus NTU 568 under dioscorea medium through the mediation of pH value and ethanol addition J. Agric. Food Chem. 2007, 55, 6493-6502
37. Lee, C. L.; Chen, W. P.; Wang, J. J.; Pan, T. M. A simple and rapid approach for removing citrinin and remaining monacolin K in red mold rice J. Agric. Food Chem. 2007, 55, 11101-11108
38. Lee, C. L.; Wang, J. J.; Pan, T. M. Synchronous analysis method for detection of citrinin and the lactone and acid forms of monacolin K in red mold rice J AOAC Int. 2006, 89, 669-677
39. Lee, C. H.; Lee, C. L.; Pan., T. M. A 90-D toxicity study of Monascus -fermented products including high citrinin level J. Food Sci. 2010, 75, 91-97