Activation of JNK and PAK2 is essential for citrinin-induced apoptosis in a human osteoblast cell line

Environmental Toxicology

Volumn 24, Issue 4, 2009, Pages 343-356

  Huang, Yu Ting ^a   Lai, Ching Yu ^a   Lou, Shyh Liang ^a   Yeh, Jui Ming ^a   Chan, Wen Hsiung ^a  

^a CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Citrinin; JNK; PAK2

Indexed keywords

ACTIVATED PROTEINS; ACTIVE CASPASE-3; ANIMAL FEED; ANTISENSE OLIGONUCLEOTIDES; APOPTOSIS; APOPTOTIC; APOPTOTIC EFFECTS; APOPTOTIC PATHWAYS; BIOCHEMICAL CHANGES; C-JUN N-TERMINAL KINASE; CASPASE; CASPASE ACTIVATION; CASPASE-3; CASPASES; CELL INJURY; CITRININ; CYTOTOXIC; GENOTOXIC EFFECTS; HUMAN OSTEOBLAST; HUMAN OSTEOBLAST CELLS; INDUCED APOPTOSIS; JNK; JNK ACTIVATION; MAMMALIAN CELLS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE EMBRYONIC STEM CELLS; NATURAL CONTAMINANTS; PAK2; SIGNALING CASCADES; SPECIFIC INHIBITORS; TWO STAGE;

BIOINFORMATICS; CELL CULTURE; CELL DEATH; ENZYME ACTIVITY; MAMMALS; OLIGONUCLEOTIDES; OSTEOBLASTS;

CELL MEMBRANES;

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTISENSE OLIGONUCLEOTIDE; CASPASE 3; CASPASE 3 INHIBITOR; CITRININ; P21 ACTIVATED KINASE 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; CYTOLOGY; ENZYME ACTIVITY; TOXIN;

APOPTOSIS; ARTICLE; BIOCHEMISTRY; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OSTEOBLAST; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

APOPTOSIS; CASPASE 3; CELL LINE; CITRININ; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MYCOTOXINS; OSTEOBLASTS; P21-ACTIVATED KINASES; REACTIVE OXYGEN SPECIES;

ANIMALIA; MAMMALIA;

EID: 67650509094     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20434     Document Type: Article

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