Bryostatin-1 vs. TPPB: Dose-dependent APP processing and PKC-α, -δ, and -ε Isoform activation in SH-SY5Y neuronal cells

Journal of Molecular Neuroscience

Volumn 48, Issue 1, 2012, Pages 234-244

  Yi, P ^a   Schrott, L ^b   Castor, T P ^c   Alexander, J S ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

^c Aphios Corporation   (United States)

Author keywords

Alpha secretase; Alzheimer's disease; Amyloid; APP; PKC; SAPP

Indexed keywords

8 (5 (4 (TRIFLUOROMETHYL) PHENYL) 2,4 PENTADIENOYLAMINO)BENZOLACTAM]; ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BRYOSTATIN 1; LACTAM DERIVATIVE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL ACTIVATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; HUMAN CELL; NERVE CELL;

ADJUVANTS, IMMUNOLOGIC; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; BENZOPYRANS; BRYOSTATINS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; NEUROBLASTOMA; NEURONS; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN KINASE C-DELTA; PROTEIN KINASE C-EPSILON;

EID: 84865120021     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9816-3     Document Type: Article

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