Resveratrol induces Sirt1-dependent apoptosis in 3T3-L1 preadipocytes by activating AMPK and suppressing AKT activity and survivin expression

Journal of Nutritional Biochemistry

Volumn 23, Issue 9, 2012, Pages 1100-1112

  Chen, Sifan ^a,b   Xiao, Xincai ^a,b   Feng, Xiang ^b   Li, Wenxue ^a   Zhou, Niman ^c   Zheng, Lin ^b   Sun, Yanshuang ^a,b   Zhang, Zili ^b   Zhu, Wei ^a  

^a GUANGZHOU CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

AMP activated protein kinase ; Apoptosis; Protein kinase B; Resveratrol; Silent information regulator 1; Survivin

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE 1 BETA D RIBOFURANOSIDE; ADENYLATE KINASE; CASPASE 3; CASPASE 9; CASPASE INHIBITOR; CYTOCHROME C; ENZYME INHIBITOR; LACTATE DEHYDROGENASE; PROTEIN KINASE B INHIBITOR; RESVERATROL; SIRTUIN 1; SURVIVIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN 3T3; CELL ULTRASTRUCTURE; CHROMATIN; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PROTEIN EXPRESSION; S PHASE CELL CYCLE CHECKPOINT; TRANSMISSION ELECTRON MICROSCOPY;

3T3-L1 CELLS; ADIPOCYTES, WHITE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE INHIBITORS; CASPASES; CHROMATIN ASSEMBLY AND DISASSEMBLY; DOWN-REGULATION; GENE SILENCING; INHIBITOR OF APOPTOSIS PROTEINS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; S PHASE; SECOND MESSENGER SYSTEMS; SIRTUIN 1; STILBENES; UP-REGULATION;

MURINAE;

EID: 84865090762     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.06.003     Document Type: Article

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