-
1
-
-
69249087671
-
Environment-mediated drug resistance: A major contributor to minimal residual disease
-
Meads, M.B.; Gatenby, R.A.; Dalton, W.S. Environment-mediated drug resistance: A major contributor to minimal residual disease. Nat. Rev. Cancer 2009, 9, 665-674.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 665-674
-
-
Meads, M.B.1
Gatenby, R.A.2
Dalton, W.S.3
-
2
-
-
65949095894
-
Multiple myeloma bone marrow niche
-
Basak, G.W.; Srivastava, A.S.; Malhotra, R.; Carrier, E. Multiple myeloma bone marrow niche. Curr. Pharm. Biotechnol. 2009, 3, 345-346.
-
(2009)
Curr. Pharm. Biotechnol
, vol.3
, pp. 345-346
-
-
Basak, G.W.1
Srivastava, A.S.2
Malhotra, R.3
Carrier, E.4
-
3
-
-
80052592013
-
Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids
-
Roodhart, J.M.; Daenen, L.G.; Stigter, E.C.; Prins, H.J.; Gerrits, J.; Houthuijzen, J.M.; Gerritsen, M.G.; Schipper, H.S.; Backer, M.J.; van Amersfoort, M., et al. Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids. Cancer Cell 2011, 3, 370-383.
-
(2011)
Cancer Cell
, vol.3
, pp. 370-383
-
-
Roodhart, J.M.1
Daenen, L.G.2
Stigter, E.C.3
Prins, H.J.4
Gerrits, J.5
Houthuijzen, J.M.6
Gerritsen, M.G.7
Schipper, H.S.8
Backer, M.J.9
van Amersfoort, M.10
-
4
-
-
84866175579
-
Ovarian ascites-derived Hospicells promote angiogenesis via activation of macrophages
-
in press
-
Castells, M.; Thibault, B.; Mery, E.; Golzio, M.; Pasquet, M.; Hennebelle, I.; Bourin, P.; Mirshahi, M.; Delord, J.P.; Querleu, D., et al. Ovarian ascites-derived Hospicells promote angiogenesis via activation of macrophages. Cancer Lett. 2012, in press.
-
(2012)
Cancer Lett
-
-
Castells, M.1
Thibault, B.2
Mery, E.3
Golzio, M.4
Pasquet, M.5
Hennebelle, I.6
Bourin, P.7
Mirshahi, M.8
Delord, J.P.9
Querleu, D.10
-
5
-
-
78649841894
-
Tumor associated mesenchymal stem cells protects ovarian cancer cells from hyperthermia through CXCL12
-
Lis, R.; Touboul, C.; Mirshahi, P.; Ali, F.; Mathew, S.; Nolan, D.J.; Maleki, M.; Abdalla, S.A.; Raynaud, C.M.; Querleu, D., et al. Tumor associated mesenchymal stem cells protects ovarian cancer cells from hyperthermia through CXCL12. Int. J. Cancer 2011, 3, 715-725.
-
(2011)
Int. J. Cancer
, vol.3
, pp. 715-725
-
-
Lis, R.1
Touboul, C.2
Mirshahi, P.3
Ali, F.4
Mathew, S.5
Nolan, D.J.6
Maleki, M.7
Abdalla, S.A.8
Raynaud, C.M.9
Querleu, D.10
-
6
-
-
79951548240
-
BMSC enhance the survival of paclitaxel treated squamous cell carcinoma cells in vitro
-
Scherzed, A.; Hackenberg, S.; Froelich, K.; Kessler, M.; Koehler, C.; Hagen, R.; Radeloff, A.; Friehs, G.; Kleinsasser, N. BMSC enhance the survival of paclitaxel treated squamous cell carcinoma cells in vitro. Cancer Biol. Ther. 2011, 3, 349-357.
-
(2011)
Cancer Biol. Ther
, vol.3
, pp. 349-357
-
-
Scherzed, A.1
Hackenberg, S.2
Froelich, K.3
Kessler, M.4
Koehler, C.5
Hagen, R.6
Radeloff, A.7
Friehs, G.8
Kleinsasser, N.9
-
7
-
-
58049204446
-
Oncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumours
-
Rafii, A.; Mirshahi, P.; Poupot, M.; Faussat, A.M.; Simon, A.; Ducros, E.; Mery, E.; Couderc, B.; Lis, R.; Capdet, J., et al. Oncologic trogocytosis of an original stromal cells induces chemoresistance of ovarian tumours. PLoS.One 2008, 12, e3894.
-
(2008)
PLoS.One
, vol.12
-
-
Rafii, A.1
Mirshahi, P.2
Poupot, M.3
Faussat, A.M.4
Simon, A.5
Ducros, E.6
Mery, E.7
Couderc, B.8
Lis, R.9
Capdet, J.10
-
8
-
-
79958191830
-
Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
-
Rohwer, N.; Cramer, T. Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways. Drug Resist.Updat. 2011, 3, 191-201.
-
(2011)
Drug Resist.Updat
, vol.3
, pp. 191-201
-
-
Rohwer, N.1
Cramer, T.2
-
9
-
-
35148881028
-
Drug resistance and the solid tumor microenvironment
-
Tredan, O.; Galmarini, C.M.; Patel, K.; Tannock, I.F. Drug resistance and the solid tumor microenvironment. J. Natl. Cancer Inst. 2007, 19, 1441-1454.
-
(2007)
J. Natl. Cancer Inst
, vol.19
, pp. 1441-1454
-
-
Tredan, O.1
Galmarini, C.M.2
Patel, K.3
Tannock, I.F.4
-
10
-
-
79959868249
-
Targeted methylation of two tumor suppressor genes is sufficient to transform mesenchymal stem cells into cancer stem/initiating cells
-
Teng, I.W.; Hou, P.C.; Lee, K.D.; Chu, P.Y.; Yeh, K.T.; Jin, V.X.; Tseng, M.J.; Tsai, S.J.; Chang, Y.S.; Wu, C.S., et al. Targeted methylation of two tumor suppressor genes is sufficient to transform mesenchymal stem cells into cancer stem/initiating cells. Cancer Res. 2011, 13, 4653-4663.
-
(2011)
Cancer Res
, vol.13
, pp. 4653-4663
-
-
Teng, I.W.1
Hou, P.C.2
Lee, K.D.3
Chu, P.Y.4
Yeh, K.T.5
Jin, V.X.6
Tseng, M.J.7
Tsai, S.J.8
Chang, Y.S.9
Wu, C.S.10
-
11
-
-
84860697028
-
The tumor microenvironment is a dominant force in multidrug resistance
-
Correia, A.L.; Bissell, M.J. The tumor microenvironment is a dominant force in multidrug resistance. Drug Resist.Updat. 2012, 15, 39-49.
-
(2012)
Drug Resist.Updat
, vol.15
, pp. 39-49
-
-
Correia, A.L.1
Bissell, M.J.2
-
12
-
-
0018729588
-
Resistance to adriamycin in multicellular spheroids
-
Sutherland, R.M.; Eddy, H.A.; Bareham, B.; Reich, K.; Vanantwerp, D. Resistance to adriamycin in multicellular spheroids. Int. J. Radiat.Oncol. Biol. Phys. 1979, 8, 1225-1230.
-
(1979)
Int. J. Radiat.Oncol. Biol. Phys
, vol.8
, pp. 1225-1230
-
-
Sutherland, R.M.1
Eddy, H.A.2
Bareham, B.3
Reich, K.4
Vanantwerp, D.5
-
13
-
-
33846558132
-
L1-CAM in a membrane- bound or soluble form augments protection from apoptosis in ovarian carcinoma cells
-
Stoeck, A.; Gast, D.; Sanderson, M.P.; Issa, Y.; Gutwein, P.; Altevogt, P. L1-CAM in a membrane- bound or soluble form augments protection from apoptosis in ovarian carcinoma cells. Gynecol.Oncol. 2007, 2, 461-469.
-
(2007)
Gynecol.Oncol
, vol.2
, pp. 461-469
-
-
Stoeck, A.1
Gast, D.2
Sanderson, M.P.3
Issa, Y.4
Gutwein, P.5
Altevogt, P.6
-
14
-
-
84858069821
-
Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma
-
Schafer, H.; Dieckmann, C.; Korniienko, O.; Moldenhauer, G.; Kiefel, H.; Salnikov, A.; Kruger, A.; Altevogt, P.; Sebens, S. Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma. Cancer Lett. 2012, 1, 66-82.
-
(2012)
Cancer Lett
, vol.1
, pp. 66-82
-
-
Schafer, H.1
Dieckmann, C.2
Korniienko, O.3
Moldenhauer, G.4
Kiefel, H.5
Salnikov, A.6
Kruger, A.7
Altevogt, P.8
Sebens, S.9
-
15
-
-
79959610127
-
Carcinoma matrix controls resistance to cisplatin through talin regulation of NF-kB
-
Eberle, K.E.; Sansing, H.A.; Szaniszlo, P.; Resto, V.A.; Berrier, A.L. Carcinoma matrix controls resistance to cisplatin through talin regulation of NF-kB. PLoS One 2011, 6, e21496.
-
(2011)
PLoS One
, vol.6
-
-
Eberle, K.E.1
Sansing, H.A.2
Szaniszlo, P.3
Resto, V.A.4
Berrier, A.L.5
-
16
-
-
10744227500
-
Genotypic and phenotypic comparisons of de novo and acquired melphalan resistance in an isogenic multiple myeloma cell line model
-
Hazlehurst, L.A.; Enkemann, S.A.; Beam, C.A.; Argilagos, R.F.; Painter, J.; Shain, K.H.; Saporta, S.; Boulware, D.; Moscinski, L.; Alsina, M., et al. Genotypic and phenotypic comparisons of de novo and acquired melphalan resistance in an isogenic multiple myeloma cell line model. Cancer Res. 2003, 22, 7900-7906.
-
(2003)
Cancer Res
, vol.22
, pp. 7900-7906
-
-
Hazlehurst, L.A.1
Enkemann, S.A.2
Beam, C.A.3
Argilagos, R.F.4
Painter, J.5
Shain, K.H.6
Saporta, S.7
Boulware, D.8
Moscinski, L.9
Alsina, M.10
-
17
-
-
0028951043
-
Dormancy of micro metastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
-
Holmgren, L.; O'Reilly, M.S.; Folkman, J. Dormancy of micro metastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat. Med. 1995, 2, 149-153.
-
(1995)
Nat. Med
, vol.2
, pp. 149-153
-
-
Holmgren, L.1
O'Reilly, M.S.2
Folkman, J.3
-
18
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
Carmeliet, P.; Jain, R.K. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011, 7347, 298-307.
-
(2011)
Nature
, vol.7347
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
19
-
-
0037699954
-
The biology of VEGF and its receptors
-
Ferrara, N.; Gerber, H.P.; Le Couter, J. The biology of VEGF and its receptors. Nat. Med. 2003, 6, 669-676.
-
(2003)
Nat. Med
, vol.6
, pp. 669-676
-
-
Ferrara, N.1
Gerber, H.P.2
Le-Couter, J.3
-
20
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
Hicklin, D.J.; Ellis, L.M. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J. Clin. Oncol. 2005, 5, 1011-1027.
-
(2005)
J. Clin. Oncol
, vol.5
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.M.2
-
21
-
-
76249106934
-
Vascular endothelial growth factor receptor-1 in human cancer: Concise review and rationale for development of IMC- 18F1 (Human antibody targeting vascular endothelial growth factor receptor-1)
-
Schwartz, J.D.; Rowinsky, E.K.; Youssoufian, H.; Pytowski, B.; Wu, Y. Vascular endothelial growth factor receptor-1 in human cancer: Concise review and rationale for development of IMC- 18F1 (Human antibody targeting vascular endothelial growth factor receptor-1). Cancer 2010, 4, S1027-S1032.
-
(2010)
Cancer
, vol.4
-
-
Schwartz, J.D.1
Rowinsky, E.K.2
Youssoufian, H.3
Pytowski, B.4
Wu, Y.5
-
22
-
-
0033861874
-
Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration
-
Dias, S.; Hattori, K.; Zhu, Z.; Heissig, B.; Choy, M.; Lane, W.; Wu, Y.; Chadburn, A.; Hyjek, E.; Gill, M., et al. Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. J. Clin. Invest. 2000, 4, 511-521.
-
(2000)
J. Clin. Invest
, vol.4
, pp. 511-521
-
-
Dias, S.1
Hattori, K.2
Zhu, Z.3
Heissig, B.4
Choy, M.5
Lane, W.6
Wu, Y.7
Chadburn, A.8
Hyjek, E.9
Gill, M.10
-
23
-
-
0036006171
-
Vascular endothelial growth factor (VEGF), a survival factor for tumour cells: Implications for anti-angiogenic therapy
-
Harmey, J.H.; Bouchier-Hayes, D. Vascular endothelial growth factor (VEGF), a survival factor for tumour cells: Implications for anti-angiogenic therapy. Bioessays 2002, 3, 280-283.
-
(2002)
Bioessays
, vol.3
, pp. 280-283
-
-
Harmey, J.H.1
Bouchier-Hayes, D.2
-
24
-
-
33749004555
-
Vascular endothelial growth factor overexpression by soft tissue sarcoma cells: Implications for tumor growth, metastasis, and chemoresistance
-
Zhang, L.; Hannay, J.A.; Liu, J.; Das, P.; Zhan, M.; Nguyen, T.; Hicklin, D.J.; Yu, D.; Pollock, R.E.; Lev, D. Vascular endothelial growth factor overexpression by soft tissue sarcoma cells: Implications for tumor growth, metastasis, and chemoresistance. Cancer Res. 2006, 17, 8770-8778.
-
(2006)
Cancer Res
, vol.17
, pp. 8770-8778
-
-
Zhang, L.1
Hannay, J.A.2
Liu, J.3
Das, P.4
Zhan, M.5
Nguyen, T.6
Hicklin, D.J.7
Yu, D.8
Pollock, R.E.9
Lev, D.10
-
25
-
-
80051676156
-
Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy
-
Yang, F.; Tang, X.; Riquelme, E.; Behrens, C.; Nilsson, M.B.; Giri, U.; Varella-Garcia, M.; Byers, L.A.; Lin, H.Y.; Wang, J., et al. Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy. Cancer Res. 2011, 16, 5512-5521.
-
(2011)
Cancer Res
, vol.16
, pp. 5512-5521
-
-
Yang, F.1
Tang, X.2
Riquelme, E.3
Behrens, C.4
Nilsson, M.B.5
Giri, U.6
Varella-Garcia, M.7
Byers, L.A.8
Lin, H.Y.9
Wang, J.10
-
26
-
-
0037007037
-
A role for survivin in chemoresistance of endothelial cells mediated by VEGF
-
Tran, J.; Master, Z.; Yu, J.L.; Rak, J.; Dumont, D.J.; Kerbel, R.S. A role for survivin in chemoresistance of endothelial cells mediated by VEGF. Proc. Natl Acad Sci. USA 2002, 7, 4349-4354.
-
(2002)
Proc. Natl Acad Sci. USA
, vol.7
, pp. 4349-4354
-
-
Tran, J.1
Master, Z.2
Yu, J.L.3
Rak, J.4
Dumont, D.J.5
Kerbel, R.S.6
-
27
-
-
33745087154
-
Survivin, a cancer target with an emerging role in normal adult tissues
-
Fukuda, S.; Pelus, L.M. Survivin, a cancer target with an emerging role in normal adult tissues. Mol. Cancer Ther. 2006, 5, 1087-1098.
-
(2006)
Mol. Cancer Ther
, vol.5
, pp. 1087-1098
-
-
Fukuda, S.1
Pelus, L.M.2
-
28
-
-
0032963472
-
Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression
-
Nor, J.E.; Christensen, J.; Mooney, D.J.; Polverini, P.J. Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am. J. Pathol. 1999, 2, 375-384.
-
(1999)
Am. J. Pathol
, vol.2
, pp. 375-384
-
-
Nor, J.E.1
Christensen, J.2
Mooney, D.J.3
Polverini, P.J.4
-
29
-
-
79952534370
-
Intracrine vascular endothelial growth factor signaling in survival and chemoresistance of human colorectal cancer cells
-
Samuel, S.; Fan, F.; Dang, L.H.; Xia, L.; Gaur, P.; Ellis, L.M. Intracrine vascular endothelial growth factor signaling in survival and chemoresistance of human colorectal cancer cells. Oncogene 2011, 10, 1205-1212.
-
(2011)
Oncogene
, vol.10
, pp. 1205-1212
-
-
Samuel, S.1
Fan, F.2
Dang, L.H.3
Xia, L.4
Gaur, P.5
Ellis, L.M.6
-
30
-
-
0036530301
-
VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition
-
Dias, S.; Shmelkov, S.V.; Lam, G.; Rafii, S. VEGF(165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition. Blood 2002, 7, 2532-2540.
-
(2002)
Blood
, vol.7
, pp. 2532-2540
-
-
Dias, S.1
Shmelkov, S.V.2
Lam, G.3
Rafii, S.4
-
31
-
-
0033522927
-
Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
-
Fujio, Y.; Walsh, K. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J. Biol. Chem. 1999, 23, 16349-16354.
-
(1999)
J. Biol. Chem
, vol.23
, pp. 16349-16354
-
-
Fujio, Y.1
Walsh, K.2
-
32
-
-
15044359505
-
VEGF-induced phosphorylation of Bcl-2 influences B lineage leukemic cell response to apoptotic stimuli
-
Wang, L.; Chen, L.; Benincosa, J.; Fortney, J.; Gibson, L.F. VEGF-induced phosphorylation of Bcl-2 influences B lineage leukemic cell response to apoptotic stimuli. Leukemia 2005, 3, 344-353.
-
(2005)
Leukemia
, vol.3
, pp. 344-353
-
-
Wang, L.1
Chen, L.2
Benincosa, J.3
Fortney, J.4
Gibson, L.F.5
-
33
-
-
0034929216
-
Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells
-
Pidgeon, G.P.; Barr, M.P.; Harmey, J.H.; Foley, D.A.; Bouchier-Hayes, D.J. Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells. Br. J. Cancer 2001, 2, 273-278.
-
(2001)
Br. J. Cancer
, vol.2
, pp. 273-278
-
-
Pidgeon, G.P.1
Barr, M.P.2
Harmey, J.H.3
Foley, D.A.4
Bouchier-Hayes, D.J.5
-
34
-
-
17144383220
-
VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: Implication for apoptosis resistance
-
Lee, Y.K.; Shanafelt, T.D.; Bone, N.D.; Strege, A.K.; Jelinek, D.F.; Kay, N.E. VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: Implication for apoptosis resistance. Leukemia 2005, 4, 513-523.
-
(2005)
Leukemia
, vol.4
, pp. 513-523
-
-
Lee, Y.K.1
Shanafelt, T.D.2
Bone, N.D.3
Strege, A.K.4
Jelinek, D.F.5
Kay, N.E.6
-
35
-
-
0242405617
-
Endothelial-pericyte interactions in angiogenesis
-
Gerhardt, H.; Betsholtz, C. Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res. 2003, 1, 15-23.
-
(2003)
Cell Tissue Res
, vol.1
, pp. 15-23
-
-
Gerhardt, H.1
Betsholtz, C.2
-
36
-
-
80052667572
-
Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression
-
Franco, M.; Roswall, P.; Cortez, E.; Hanahan, D.; Pietras, K. Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression. Blood 2011, 10, 2906-2917.
-
(2011)
Blood
, vol.10
, pp. 2906-2917
-
-
Franco, M.1
Roswall, P.2
Cortez, E.3
Hanahan, D.4
Pietras, K.5
-
37
-
-
33751207110
-
VEGF, a prosurvival factor, acts in concert with TGF-beta1 to induce endothelial cell apoptosis
-
Ferrari, G.; Pintucci, G.; Seghezzi, G.; Hyman, K.; Galloway, A.C.; Mignatti, P. VEGF, a prosurvival factor, acts in concert with TGF-beta1 to induce endothelial cell apoptosis. Proc. Natl. Acad Sci. USA 2006, 46, 17260-17265.
-
(2006)
Proc. Natl. Acad Sci. USA
, vol.46
, pp. 17260-17265
-
-
Ferrari, G.1
Pintucci, G.2
Seghezzi, G.3
Hyman, K.4
Galloway, A.C.5
Mignatti, P.6
-
38
-
-
70449360912
-
Chemo resistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells
-
doi:10.1186/1476-4598-8-80
-
Michaelis, M.; Klassert, D.; Barth, S.; Suhan, T.; Breitling, R.; Mayer, B.; Hinsch, N.; Doerr, H.W.; Cinatl, J.; Cinatl, J., Jr. Chemo resistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells. Mol. Cancer 2009, doi:10.1186/1476-4598-8-80.
-
(2009)
Mol. Cancer
-
-
Michaelis, M.T.1
Breitling, R.2
Mayer, B.3
Hinsch, N.4
Doerr, H.W.5
Cinatl, J.6
Cinatl Jr., J.7
-
39
-
-
0034120314
-
Bcl-2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line
-
Biroccio, A.; Candiloro, A.; Mottolese, M.; Sapora, O.; Albini, A.; Zupi, G.; del Bufalo, D. Bcl-2 overexpression and hypoxia synergistically act to modulate vascular endothelial growth factor expression and in vivo angiogenesis in a breast carcinoma line. FASEB J. 2000, 5, 652-660.
-
(2000)
FASEB J
, vol.5
, pp. 652-660
-
-
Biroccio, A.1
Candiloro, A.2
Mottolese, M.3
Sapora, O.4
Albini, A.5
Zupi, G.6
del Bufalo, D.7
-
40
-
-
33846817095
-
Knock-down of Bcl-2 by antisense oligodeoxynucleotides induces radiosensitization and inhibition of angiogenesis in human PC-3 prostate tumor xenografts
-
Anai, S.; Goodison, S.; Shiverick, K.; Hirao, Y.; Brown, B.D.; Rosser, C.J. Knock-down of Bcl-2 by antisense oligodeoxynucleotides induces radiosensitization and inhibition of angiogenesis in human PC-3 prostate tumor xenografts. Mol. Cancer Ther. 2007, 1, 101-111.
-
(2007)
Mol. Cancer Ther
, vol.1
, pp. 101-111
-
-
Anai, S.1
Goodison, S.2
Shiverick, K.3
Hirao, Y.4
Brown, B.D.5
Rosser, C.J.6
-
41
-
-
14944359615
-
Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant
-
Tu, S.P.; Cui, J.T.; Liston, P.; Huajiang, X.; Xu, R.; Lin, M.C.; Zhu, Y.B.; Zou, B.; Ng, S.S.; Jiang, S.H., et al. Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant. Gastroenterology 2005, 2, 361-375.
-
(2005)
Gastroenterology
, vol.2
, pp. 361-375
-
-
Tu, S.P.1
Cui, J.T.2
Liston, P.3
Huajiang, X.4
Xu, R.5
Lin, M.C.6
Zhu, Y.B.7
Zou, B.8
Ng, S.S.9
Jiang, S.H.10
-
42
-
-
0028238298
-
Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo
-
Fuks, Z.; Persaud, R.S.; Alfieri, A.; McLoughlin, M.; Ehleiter, D.; Schwartz, J.L.; Seddon, A.P.; Cordon-Cardo, C.; Haimovitz-Friedman, A. Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo. Cancer Res. 1994, 10, 2582-2590.
-
(1994)
Cancer Res
, vol.10
, pp. 2582-2590
-
-
Fuks, Z.1
Persaud, R.S.2
Alfieri, A.3
McLoughlin, M.4
Ehleiter, D.5
Schwartz, J.L.6
Seddon, A.P.7
Cordon-Cardo, C.8
Haimovitz-Friedman, A.9
-
43
-
-
0030696785
-
Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms
-
Karsan, A.; Yee, E.; Poirier, G.G.; Zhou, P.; Craig, R.; Harlan, J.M. Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms. Am. J. Pathol. 1997, 6, 1775-1784.
-
(1997)
Am. J. Pathol
, vol.6
, pp. 1775-1784
-
-
Karsan, A.1
Yee, E.2
Poirier, G.G.3
Zhou, P.4
Craig, R.5
Harlan, J.M.6
-
44
-
-
0033870417
-
Control of apoptosis during angiogenesis by survivin expression in endothelial cells
-
O'Connor, D.S.; Schechner, J.S.; Adida, C.; Mesri, M.; Rothermel, A.L.; Li, F.; Nath, A.K.; Pober, J.S.; Altieri, D.C. Control of apoptosis during angiogenesis by survivin expression in endothelial cells. Am. J. Pathol. 2000, 2, 393-398.
-
(2000)
Am. J. Pathol
, vol.2
, pp. 393-398
-
-
O'Connor, D.S.1
Schechner, J.S.2
Adida, C.3
Mesri, M.4
Rothermel, A.L.5
Li, F.6
Nath, A.K.7
Pober, J.S.8
Altieri, D.C.9
-
45
-
-
0033597718
-
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis
-
Carmeliet, P.; Lampugnani, M.G.; Moons, L.; Breviario, F.; Compernolle, V.; Bono, F.; Balconi, G.; Spagnuolo, R.; Oosthuyse, B.; Dewerchin, M., et al. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell 1999, 2, 147-157.
-
(1999)
Cell
, vol.2
, pp. 147-157
-
-
Carmeliet, P.1
Lampugnani, M.G.2
Moons, L.3
Breviario, F.4
Compernolle, V.5
Bono, F.6
Balconi, G.7
Spagnuolo, R.8
Oosthuyse, B.9
Dewerchin, M.10
-
46
-
-
0036072017
-
Regulation of endothelial cell survival and apoptosis during angiogenesis
-
Chavakis, E.; Dimmeler, S. Regulation of endothelial cell survival and apoptosis during angiogenesis. Arterioscler. Thromb. Vasc. Biol 2002, 6, 887-893.
-
(2002)
Arterioscler. Thromb. Vasc. Biol
, vol.6
, pp. 887-893
-
-
Chavakis, E.1
Dimmeler, S.2
-
47
-
-
2342607910
-
Glioblastoma cells block radiation-induced programmed cell death of endothelial cells
-
Brown, C.K.; Khodarev, N.N.; Yu, J.; Moo-Young, T.; Labay, E.; Darga, T.E.; Posner, M.C.; Weichselbaum, R.R.; Mauceri, H.J. Glioblastoma cells block radiation-induced programmed cell death of endothelial cells. FEBS Lett. 2004, 1-3, 167-170.
-
(2004)
FEBS Lett
, vol.1-3
, pp. 167-170
-
-
Brown, C.K.1
Khodarev, N.N.2
Yu, J.3
Moo-Young, T.4
Labay, E.5
Darga, T.E.6
Posner, M.C.7
Weichselbaum, R.R.8
Mauceri, H.J.9
-
48
-
-
33144472892
-
-
Fonsato, V.; Buttiglieri, S.; Deregibus, M.C.; Puntorieri, V.; Bussolati, B.; Camussi, G. Expression of Pax2 in human renal tumor-derived endothelial cells sustains apoptosis resistance and angiogenesis. Am. J. Pathol. 2006, 2, 706-713.
-
(2006)
Expression of Pax2 In Human Renal Tumor-derived Endothelial Cells Sustains Apoptosis Resistance and Angiogenesis
, vol.2
, pp. 706-713
-
-
Fonsato, V.1
Buttiglieri, S.2
Deregibus, M.C.3
Puntorieri, V.4
Bussolati, B.5
Camussi, G.6
-
49
-
-
48749089520
-
Increased surviving expression confers chemoresistance to tumor-associated endothelial cells
-
Virrey, J.J.; Guan, S.; Li, W.; Schonthal, A.H.; Chen, T.C.; Hofman, F.M. Increased surviving expression confers chemoresistance to tumor-associated endothelial cells. Am. J. Pathol. 2008, 2, 575-585.
-
(2008)
Am. J. Pathol
, vol.2
, pp. 575-585
-
-
Virrey, J.J.1
Guan, S.2
Li, W.3
Schonthal, A.H.4
Chen, T.C.5
Hofman, F.M.6
-
50
-
-
34547790207
-
Chemotherapeutic stress selectively activates NF-kappa B- dependent AKT and VEGF expression in liver cancer-derived endothelial cells
-
Meng, F.; Henson, R.; Patel, T. Chemotherapeutic stress selectively activates NF-kappa B- dependent AKT and VEGF expression in liver cancer-derived endothelial cells. Am. J. Physiol. Cell Physiol. 2007, 2, C749-C760.
-
(2007)
Am. J. Physiol. Cell Physiol
, vol.2
-
-
Meng, F.1
Henson, R.2
Patel, T.3
-
51
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim, K.J.; Li, B.; Winer, J.; Armanini, M.; Gillett, N.; Phillips, H.S.; Ferrara, N. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993, 6423, 841-844.
-
(1993)
Nature
, vol.6423
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
Ferrara, N.7
-
52
-
-
0034306974
-
Anti-Vascular endothelial growth factor treatment augments tumor radiation response under nor moxic or hypoxic conditions
-
Lee, C.G.; Heijn, M.; di Tomaso, E.; Griffon-Etienne, G.; Ancukiewicz, M.; Koike, C.; Park, K.R.; Ferrara, N.; Jain, R.K.; Suit, H.D.; Boucher, Y. Anti-Vascular endothelial growth factor treatment augments tumor radiation response under nor moxic or hypoxic conditions. Cancer Res. 2000, 19, 5565-5570.
-
(2000)
Cancer Res
, vol.19
, pp. 5565-5570
-
-
Lee, C.G.1
Heijn, M.2
di Tomaso, E.3
Griffon-Etienne, G.4
Ancukiewicz, M.5
Koike, C.6
Park, K.R.7
Ferrara, N.8
Jain, R.K.9
Suit, H.D.10
Boucher, Y.11
-
53
-
-
2542628099
-
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
-
Tong, R.T.; Boucher, Y.; Kozin, S.V.; Winkler, F.; Hicklin, D.J.; Jain, R.K. Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res. 2004, 11, 3731-3736.
-
(2004)
Cancer Res
, vol.11
, pp. 3731-3736
-
-
Tong, R.T.1
Boucher, Y.2
Kozin, S.V.3
Winkler, F.4
Hicklin, D.J.5
Jain, R.K.6
-
54
-
-
0029944122
-
Angiostatin induces and sustains dormancy of human primary tumors in mice
-
Oreilly, M.S.; Holmgren, L.; Chen, C.; Folkman, J. Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat. Med. 1996, 6, 689-692.
-
(1996)
Nat. Med
, vol.6
, pp. 689-692
-
-
Oreilly, M.S.1
Holmgren, L.2
Chen, C.3
Folkman, J.4
-
55
-
-
79957894276
-
Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
-
Carmeliet, P.; Jain, R.K. Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nat. Rev. Drug Discov. 2011, 6, 417-427.
-
(2011)
Nat. Rev. Drug Discov
, vol.6
, pp. 417-427
-
-
Carmeliet, P.1
Jain, R.K.2
-
56
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
Willett, C.G.; Boucher, Y.; di Tomaso, E.; Duda, D.G.; Munn, L.L.; Tong, R.T.; Chung, D.C.; Sahani, D.V.; Kalva, S.P.; Kozin, S.V., et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat. Med. 2004, 2, 145-147.
-
(2004)
Nat. Med
, vol.2
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
di Tomaso, E.3
Duda, D.G.4
Munn, L.L.5
Tong, R.T.6
Chung, D.C.7
Sahani, D.V.8
Kalva, S.P.9
Kozin, S.V.10
-
57
-
-
77952809712
-
Effects of bevacizumab plus irinotecan on response and survival in patients with recurrent malignant glioma: A systematic review and survival-gain analysis
-
doi:10.1186/1471-2407-10-252
-
Xu, T.; Chen, J.; Lu, Y.; Wolff, J.E. Effects of bevacizumab plus irinotecan on response and survival in patients with recurrent malignant glioma: A systematic review and survival-gain analysis. BMC Cancer 2010, doi:10.1186/1471-2407-10-252.
-
(2010)
BMC Cancer
-
-
Xu, T.1
Chen, J.2
Lu, Y.3
Wolff, J.E.4
-
58
-
-
2542520723
-
Two steps forward in the treatment of colorectal cancer
-
Mayer, R.J. Two steps forward in the treatment of colorectal cancer. N. Engl. J. Med. 2004, 23, 2406-2408.
-
(2004)
N. Engl. J. Med
, vol.23
, pp. 2406-2408
-
-
Mayer, R.J.1
-
59
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antian giogenic therapy
-
Jain, R.K. Normalization of tumor vasculature: An emerging concept in antian giogenic therapy. Science 2005, 5706, 58-62.
-
(2005)
Science
, vol.5706
, pp. 58-62
-
-
Jain, R.K.1
-
60
-
-
79959944026
-
Antiangiogenic therapy, hypoxia, and metastasis: Risky liaisons, or not?
-
De Bock, K.; Mazzone, M.; Carmeliet, P. Antiangiogenic therapy, hypoxia, and metastasis: Risky liaisons, or not? Nat. Rev. Clin. Oncol. 2011, 7, 393-404.
-
(2011)
Nat. Rev. Clin. Oncol
, vol.7
, pp. 393-404
-
-
de Bock, K.1
Mazzone, M.2
Carmeliet, P.3
-
61
-
-
79551628206
-
Hypoxia and energetic tumour metabolism
-
Brahimi-Horn, M.C.; Bellot, G.; Pouyssegur, J. Hypoxia and energetic tumour metabolism. Curr.Opin.Genet. Dev. 2011, 1, 67-72.
-
(2011)
Curr.Opin.Genet. Dev
, vol.1
, pp. 67-72
-
-
Brahimi-Horn, M.C.1
Bellot, G.2
Pouyssegur, J.3
-
62
-
-
0038172576
-
Cancer: Out of air is not out of action
-
Bottaro, D.P.; Liotta, L.A. Cancer: Out of air is not out of action. Nature 2003, 6940, 593-595.
-
(2003)
Nature
, vol.6940
, pp. 593-595
-
-
Bottaro, D.P.1
Liotta, L.A.2
-
63
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza, G.L. Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 2003, 10, 721-732.
-
(2003)
Nat. Rev. Cancer
, vol.10
, pp. 721-732
-
-
Semenza, G.L.1
-
64
-
-
0029103274
-
Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer
-
Liu, Y.; Cox, S.R.; Morita, T.; Kourembanas, S. Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer. Circ. Res. 1995, 3, 638-643.
-
(1995)
Circ. Res
, vol.3
, pp. 638-643
-
-
Liu, Y.1
Cox, S.R.2
Morita, T.3
Kourembanas, S.4
-
66
-
-
1642472018
-
Antiangiogenic therapy and tumor progression
-
Blagosklonny, M.V. Antiangiogenic therapy and tumor progression. Cancer Cell 2004, 1, 13-17.
-
(2004)
Cancer Cell
, vol.1
, pp. 13-17
-
-
Blagosklonny, M.V.1
-
67
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos, J.M.; Lee, C.R.; Cruz-Munoz, W.; Bjarnason, G.A.; Christensen, J.G.; Kerbel, R.S. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 2009, 3, 232-239.
-
(2009)
Cancer Cell
, vol.3
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
-
68
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes, M.; Allen, E.; Hudock, J.; Takeda, T.; Okuyama, H.; Vinals, F.; Inoue, M.; Bergers, G.; Hanahan, D.; Casanovas, O. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009, 3, 220-231.
-
(2009)
Cancer Cell
, vol.3
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Vinals, F.6
Inoue, M.7
Bergers, G.8
Hanahan, D.9
Casanovas, O.10
-
69
-
-
77954700380
-
Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
-
Miles, D.W.; Chan, A.; Dirix, L.Y.; Cortes, J.; Pivot, X.; Tomczak, P.; Delozier, T.; Sohn, J.H.; Provencher, L.; Puglisi, F., et al. Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J. Clin. Oncol. 2010, 20, 3239-3247.
-
(2010)
J. Clin. Oncol
, vol.20
, pp. 3239-3247
-
-
Miles, D.W.1
Chan, A.2
Dirix, L.Y.3
Cortes, J.4
Pivot, X.5
Tomczak, P.6
Delozier, T.7
Sohn, J.H.8
Provencher, L.9
Puglisi, F.10
-
70
-
-
50149109090
-
Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib
-
Padera, T.P.; Kuo, A.H.; Hoshida, T.; Liao, S.; Lobo, J.; Kozak, K.R.; Fukumura, D.; Jain, R.K. Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib. Mol. Cancer Ther. 2008, 8, 2272-2279.
-
(2008)
Mol. Cancer Ther
, vol.8
, pp. 2272-2279
-
-
Padera, T.P.1
Kuo, A.H.2
Hoshida, T.3
Liao, S.4
Lobo, J.5
Kozak, K.R.6
Fukumura, D.7
Jain, R.K.8
-
71
-
-
0032450975
-
Interdependence between cytokines and cell adhesion molecules to induce interleukin-6 production by stromal cells in myeloma
-
Thomas, X.; Anglaret, B.; Magaud, J.P.; Epstein, J.; Archimbaud, E. Interdependence between cytokines and cell adhesion molecules to induce interleukin-6 production by stromal cells in myeloma. Leuk. Lymphoma 1998, 32, 107-119.
-
(1998)
Leuk. Lymphoma
, vol.32
, pp. 107-119
-
-
Thomas, X.1
Anglaret, B.2
Magaud, J.P.3
Epstein, J.4
Archimbaud, E.5
-
72
-
-
0034501628
-
The tumor microenvironment as a determinant of cancer cell survival: A possible mechanism for de novo drug resistance
-
Shain, K.H.; Landowski, T.H.; Dalton, W.S. The tumor microenvironment as a determinant of cancer cell survival: A possible mechanism for de novo drug resistance. Curr. Opin. Oncol. 2000, 6, 557-563.
-
(2000)
Curr. Opin. Oncol
, vol.6
, pp. 557-563
-
-
Shain, K.H.1
Landowski, T.H.2
Dalton, W.S.3
-
73
-
-
77951233373
-
Cancer associated fibroblasts (CAFs) in tumor microenvironment
-
Xing, F.; Saidou, J.; Watabe, K. Cancer associated fibroblasts (CAFs) in tumor microenvironment. Front Biosci. 2010, 15, 166-179.
-
(2010)
Front Biosci
, vol.15
, pp. 166-179
-
-
Xing, F.1
Saidou, J.2
Watabe, K.3
-
74
-
-
84655169986
-
The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma
-
Sirica, A.E. The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma. Nat. Rev. Gastroenterol. Hepatol. 2012, 1, 44-54.
-
(2012)
Nat. Rev. Gastroenterol. Hepatol
, vol.1
, pp. 44-54
-
-
Sirica, A.E.1
-
75
-
-
82455210969
-
Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells
-
Fingas, C.D.; Bronk, S.F.; Werneburg, N.W.; Mott, J.L.; Guicciardi, M.E.; Cazanave, S.C.; Mertens, J.C.; Sirica, A.E.; Gores, G.J. Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells. Hepatology 2011, 6, 2076-2088.
-
(2011)
Hepatology
, vol.6
, pp. 2076-2088
-
-
Fingas, C.D.1
Bronk, S.F.2
Werneburg, N.W.3
Mott, J.L.4
Guicciardi, M.E.5
Cazanave, S.C.6
Mertens, J.C.7
Sirica, A.E.8
Gores, G.J.9
-
76
-
-
67650451085
-
The multifaceted role of periostin in tumorigenesis
-
Ruan, K.; Bao, S.; Ouyang, G. The multifaceted role of periostin in tumorigenesis. Cell Mol. Life Sci. 2009, 14, 2219-2230.
-
(2009)
Cell Mol. Life Sci
, vol.14
, pp. 2219-2230
-
-
Ruan, K.1
Bao, S.2
Ouyang, G.3
-
77
-
-
0033579444
-
Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
-
Park, J.E.; Lenter, M.C.; Zimmermann, R.N.; Garin-Chesa, P.; Old, L.J.; Rettig, W.J. Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts. J. Biol. Chem. 1999, 51, 36505-36512.
-
(1999)
J. Biol. Chem
, vol.51
, pp. 36505-36512
-
-
Park, J.E.1
Lenter, M.C.2
Zimmermann, R.N.3
Garin-Chesa, P.4
Old, L.J.5
Rettig, W.J.6
-
78
-
-
4944266313
-
High interstitial fluid pressure-an obstacle in cancer therapy
-
Heldin, C.H.; Rubin, K.; Pietras, K.; Ostman, A. High interstitial fluid pressure-an obstacle in cancer therapy. Nat. Rev. Cancer 2004, 10, 806-813.
-
(2004)
Nat. Rev. Cancer
, vol.10
, pp. 806-813
-
-
Heldin, C.H.1
Rubin, K.2
Pietras, K.3
Ostman, A.4
-
79
-
-
48149105146
-
Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells
-
Serebriiskii, I.; Castello-Cros, R.; Lamb, A.; Golemis, E.A.; Cukierman, E. Fibroblast-derived 3D matrix differentially regulates the growth and drug-responsiveness of human cancer cells. Matrix. Biol. 2008, 6, 573-585.
-
(2008)
Matrix. Biol
, vol.6
, pp. 573-585
-
-
Serebriiskii, I.1
Castello-Cros, R.2
Lamb, A.3
Golemis, E.A.4
Cukierman, E.5
-
80
-
-
51949094991
-
Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases
-
Muerkoster, S.S.; Werbing, V.; Koch, D.; Sipos, B.; Ammerpohl, O.; Kalthoff, H.; Tsao, M.S.; Folsch, U.R.; Schafer, H. Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases. Int. J. Cancer 2008, 8, 1751-1760.
-
(2008)
Int. J. Cancer
, vol.8
, pp. 1751-1760
-
-
Muerkoster, S.S.1
Werbing, V.2
Koch, D.3
Sipos, B.4
Ammerpohl, O.5
Kalthoff, H.6
Tsao, M.S.7
Folsch, U.R.8
Schafer, H.9
-
81
-
-
33644833474
-
Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: Phase II study results
-
Reardon, D.A.; Akabani, G.; Coleman, R.E.; Friedman, A.H.; Friedman, H.S.; Herndon, J.E.; McLendon, R.E.; Pegram, C.N.; Provenzale, J.M.; Quinn, J.A., et al. Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: Phase II study results. J. Clin. Oncol. 2006, 1, 115-122.
-
(2006)
J. Clin. Oncol
, vol.1
, pp. 115-122
-
-
Reardon, D.A.1
Akabani, G.2
Coleman, R.E.3
Friedman, A.H.4
Friedman, H.S.5
Herndon, J.E.6
McLendon, R.E.7
Pegram, C.N.8
Provenzale, J.M.9
Quinn, J.A.10
-
82
-
-
33745837774
-
Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
-
Loeffler, M.; Kruger, J.A.; Niethammer, A.G.; Reisfeld, R.A. Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J. Clin. Invest. 2006, 7, 1955-1962.
-
(2006)
J. Clin. Invest
, vol.7
, pp. 1955-1962
-
-
Loeffler, M.1
Kruger, J.A.2
Niethammer, A.G.3
Reisfeld, R.A.4
-
83
-
-
34247472169
-
Towards in situ tissue repair: Human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2
-
Ringe, J.; Strassburg, S.; Neumann, K.; Endres, M.; Notter, M.; Burmester, G.R.; Kaps, C.; Sittinger, M. Towards in situ tissue repair: Human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2. J. Cell Biochem. 2007, 1, 135-146.
-
(2007)
J. Cell Biochem
, vol.1
, pp. 135-146
-
-
Ringe, J.1
Strassburg, S.2
Neumann, K.3
Endres, M.4
Notter, M.5
Burmester, G.R.6
Kaps, C.7
Sittinger, M.8
-
84
-
-
77949886426
-
Hospicells (ascites-derived stromal cells) promote tumorigenicity and angiogenesis
-
Pasquet, M.; Golzio, M.; Mery, E.; Rafii, A.; Benabbou, N.; Mirshahi, P.; Hennebelle, I.; Bourin, P.; Allal, B.; Teissie, J., et al. Hospicells (ascites-derived stromal cells) promote tumorigenicity and angiogenesis. Int. J. Cancer 2010, 9, 2090-2101.
-
(2010)
Int. J. Cancer
, vol.9
, pp. 2090-2101
-
-
Pasquet, M.1
Golzio, M.2
Mery, E.3
Rafii, A.4
Benabbou, N.5
Mirshahi, P.6
Hennebelle, I.7
Bourin, P.8
Allal, B.9
Teissie, J.10
-
85
-
-
77953023138
-
Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence
-
Rhodes, L.V.; Muir, S.E.; Elliott, S.; Guillot, L.M.; Antoon, J.W.; Penfornis, P.; Tilghman, S.L.; Salvo, V.A.; Fonseca, J.P.; Lacey, M.R., et al. Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence. Breast Cancer Res. Treat. 2010, 2, 293-300.
-
(2010)
Breast Cancer Res. Treat
, vol.2
, pp. 293-300
-
-
Rhodes, L.V.1
Muir, S.E.2
Elliott, S.3
Guillot, L.M.4
Antoon, J.W.5
Penfornis, P.6
Tilghman, S.L.7
Salvo, V.A.8
Fonseca, J.P.9
Lacey, M.R.10
-
86
-
-
34948896045
-
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
-
Karnoub, A.E.; Dash, A.B.; Vo, A.P.; Sullivan, A.; Brooks, M.W.; Bell, G.W.; Richardson, A.L.; Polyak, K.; Tubo, R.; Weinberg, R.A. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007, 7162, 557-563.
-
(2007)
Nature
, vol.7162
, pp. 557-563
-
-
Karnoub, A.E.1
Dash, A.B.2
Vo, A.P.3
Sullivan, A.4
Brooks, M.W.5
Bell, G.W.6
Richardson, A.L.7
Polyak, K.8
Tubo, R.9
Weinberg, R.A.10
-
87
-
-
47249119717
-
TGF-beta receptor kinase inhibitor LY2109761 reverses the anti-apoptotic effects of TGF-beta1 in myelo-monocytic leukaemic cells co-cultured with stromal cells
-
Xu, Y.; Tabe, Y.; Jin, L.; Watt, J.; McQueen, T.; Ohsaka, A.; Andreeff, M.; Konopleva, M. TGF-beta receptor kinase inhibitor LY2109761 reverses the anti-apoptotic effects of TGF-beta1 in myelo-monocytic leukaemic cells co-cultured with stromal cells. Br. J. Haematol. 2008, 2, 192-201.
-
(2008)
Br. J. Haematol
, vol.2
, pp. 192-201
-
-
Xu, Y.1
Tabe, Y.2
Jin, L.3
Watt, J.4
McQueen, T.5
Ohsaka, A.6
Andreeff, M.7
Konopleva, M.8
-
88
-
-
80052062422
-
Bone marrow stromal cells protect myeloma cells from bortezomib induced apoptosis by suppressing microRNA-15a expression
-
Hao, M.; Zhang, L.; An, G.; Meng, H.; Han, Y.; Xie, Z.; Xu, Y.; Li, C.; Yu, Z.; Chang, H.; Qiu, L. Bone marrow stromal cells protect myeloma cells from bortezomib induced apoptosis by suppressing microRNA-15a expression. Leuk. Lymphoma 2011, 9, 1787-1794.
-
(2011)
Leuk. Lymphoma
, vol.9
, pp. 1787-1794
-
-
Hao, M.1
Zhang, L.2
An, G.3
Meng, H.4
Han, Y.5
Xie, Z.6
Xu, Y.7
Li, C.8
Yu, Z.9
Chang, H.10
Qiu, L.11
-
89
-
-
38349086394
-
CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells
-
Jin, L.; Tabe, Y.; Konoplev, S.; Xu, Y.; Leysath, C.E.; Lu, H.; Kimura, S.; Ohsaka, A.; Rios, M.B.; Calvert, L., et al. CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells. Mol. Cancer Ther. 2008, 1, 48-58.
-
(2008)
Mol. Cancer Ther
, vol.1
, pp. 48-58
-
-
Jin, L.1
Tabe, Y.2
Konoplev, S.3
Xu, Y.4
Leysath, C.E.5
Lu, H.6
Kimura, S.7
Ohsaka, A.8
Rios, M.B.9
Calvert, L.10
-
90
-
-
80051628334
-
Pronounced hypoxia in models of murine and human leukemia: High efficacy of hypoxia-activated prodrug PR-104
-
Benito, J.; Shi, Y.; Szymanska, B.; Carol, H.; Boehm, I.; Lu, H.; Konoplev, S.; Fang, W.; Zweidler-Ckay, P.A.; Campana, D., et al. Pronounced hypoxia in models of murine and human leukemia: High efficacy of hypoxia-activated prodrug PR-104. PLoS One 2011, 8, e23108.
-
(2011)
PLoS One
, vol.8
-
-
Benito, J.1
Shi, Y.2
Szymanska, B.3
Carol, H.4
Boehm, I.5
Lu, H.6
Konoplev, S.7
Fang, W.8
Zweidler-Ckay, P.A.9
Campana, D.10
-
91
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D.; Weinberg, R.A. Hallmarks of cancer: The next generation. Cell 2011, 5, 646-674.
-
(2011)
Cell
, vol.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
92
-
-
0036623140
-
Immune escape of tumors: Apoptosis resistance and tumor counterattack
-
Igney, F.H.; Krammer, P.H. Immune escape of tumors: Apoptosis resistance and tumor counterattack. J. Leukoc. Biol. 2002, 6, 907-920.
-
(2002)
J. Leukoc. Biol
, vol.6
, pp. 907-920
-
-
Igney, F.H.1
Krammer, P.H.2
-
93
-
-
34547820876
-
Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells
-
Shojaei, F.; Wu, X.; Malik, A.K.; Zhong, C.; Baldwin, M.E.; Schanz, S.; Fuh, G.; Gerber, H.P.; Ferrara, N. Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells. Nat. Biotechnol. 2007, 8, 911-920.
-
(2007)
Nat. Biotechnol
, vol.8
, pp. 911-920
-
-
Shojaei, F.1
Wu, X.2
Malik, A.K.3
Zhong, C.4
Baldwin, M.E.5
Schanz, S.6
Fuh, G.7
Gerber, H.P.8
Ferrara, N.9
-
94
-
-
35548982639
-
Anti-PlGF inhibits growth of VEGF(R)- inhibitor-resistant tumors without affecting healthy vessels
-
Fischer, C.; Jonckx, B.; Mazzone, M.; Zacchigna, S.; Loges, S.; Pattarini, L.; Chorianopoulos, E.; Liesenborghs, L.; Koch, M.; de Mol, M., et al. Anti-PlGF inhibits growth of VEGF(R)- inhibitor-resistant tumors without affecting healthy vessels. Cell 2007, 3, 463-475.
-
(2007)
Cell
, vol.3
, pp. 463-475
-
-
Fischer, C.1
Jonckx, B.2
Mazzone, M.3
Zacchigna, S.4
Loges, S.5
Pattarini, L.6
Chorianopoulos, E.7
Liesenborghs, L.8
Koch, M.9
de Mol, M.10
-
95
-
-
42149099408
-
Plasticity of macrophage function during tumor progression: Regulation by distinct molecular mechanisms
-
Biswas, S.K.; Sica, A.; Lewis, C.E. Plasticity of macrophage function during tumor progression: Regulation by distinct molecular mechanisms. J. Immunol. 2008, 4, 2011-2017.
-
(2008)
J. Immunol
, vol.4
, pp. 2011-2017
-
-
Biswas, S.K.1
Sica, A.2
Lewis, C.E.3
-
96
-
-
84866784798
-
Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy
-
doi:10.1158/2159-8274
-
Denardo, D.G.; Brennan, D.J.; Rexhepaj, E.; Ruffell, B.; Shiao, S.L.; Madden, S.F.; Gallagher, W.M.; Wadhwani, N.; Keil, S.D.; Junaid, S.A., et al. Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy. Cancer Discov. 2011, doi:10.1158/2159-8274.
-
(2011)
Cancer Discov
-
-
Denardo, D.G.1
Brennan, D.J.2
Rexhepaj, E.3
Ruffell, B.4
Shiao, S.L.5
Madden, S.F.6
Gallagher, W.M.7
Wadhwani, N.8
Keil, S.D.9
Junaid, S.A.10
-
97
-
-
82955189189
-
Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer
-
Shree, T.; Olson, O.C.; Elie, B.T.; Kester, J.C.; Garfall, A.L.; Simpson, K.; Bell-McGuinn, K.M.; Zabor, E.C.; Brogi, E.; Joyce, J.A. Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer. Genes Dev. 2011, 23, 2465-2479.
-
(2011)
Genes Dev
, vol.23
, pp. 2465-2479
-
-
Shree, T.1
Olson, O.C.2
Elie, B.T.3
Kester, J.C.4
Garfall, A.L.5
Simpson, K.6
Bell-McGuinn, K.M.7
Zabor, E.C.8
Brogi, E.9
Joyce, J.A.10
-
98
-
-
45049085722
-
Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2
-
Angst, E.; Reber, H.A.; Hines, O.J.; Eibl, G. Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2. Surgery 2008, 1, 57-65.
-
(2008)
Surgery
, vol.1
, pp. 57-65
-
-
Angst, E.1
Reber, H.A.2
Hines, O.J.3
Eibl, G.4
-
99
-
-
64049092886
-
The localization and density of immune cells in primary tumors of human metastatic colorectal cancer shows an association with response to chemotherapy
-
Halama, N.; Michel, S.; Kloor, M.; Zoernig, I.; Pommerencke, T.; von Knebel Doeberitz, M.; Schirmacher, P.; Weitz, J.; Grabe, N.; Jager, D. The localization and density of immune cells in primary tumors of human metastatic colorectal cancer shows an association with response to chemotherapy. Cancer Immun. 2009, 9, 1.
-
(2009)
Cancer Immun
, vol.9
, pp. 1
-
-
Halama, N.1
Michel, S.2
Kloor, M.3
Zoernig, I.4
Pommerencke, T.5
von Knebel, D.M.6
Schirmacher, P.7
Weitz, J.8
Grabe, N.9
Jager, D.10
-
100
-
-
80052227854
-
Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy
-
Halama, N.; Michel, S.; Kloor, M.; Zoernig, I.; Benner, A.; Spille, A.; Pommerencke, T.; von Knebel, D.M.; Folprecht, G.; Luber, B., et al. Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy. Cancer Res. 2011, 17, 5670-5677.
-
(2011)
Cancer Res
, vol.17
, pp. 5670-5677
-
-
Halama, N.1
Michel, S.2
Kloor, M.3
Zoernig, I.4
Benner, A.5
Spille, A.6
Pommerencke, T.7
von Knebel, D.M.8
Folprecht, G.9
Luber, B.10
-
101
-
-
73949092850
-
Tumor-associated lymphocytes as an independent redictor of response to neoadjuvant chemotherapy in breast cancer
-
Denkert, C.; Loibl, S.; Noske, A.; Roller, M.; Muller, B.M.; Komor, M.; Budczies, J.; Darb-Esfahani, S.; Kronenwett, R.; Hanusch, C., et al. Tumor-associated lymphocytes as an independent redictor of response to neoadjuvant chemotherapy in breast cancer. J. Clin. Oncol. 2010, 1, 105-113.
-
(2010)
J. Clin. Oncol
, vol.1
, pp. 105-113
-
-
Denkert, C.1
Loibl, S.2
Noske, A.3
Roller, M.4
Muller, B.M.5
Komor, M.6
Budczies, J.7
Darb-Esfahani, S.8
Kronenwett, R.9
Hanusch, C.10
-
102
-
-
70349170354
-
Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth
-
Van der Most, R.G.; Currie, A.J.; Cleaver, A.L.; Salmons, J.; Nowak, A.K.; Mahendran, S.; Larma, I.; Prosser, A.; Robinson, B.W.; Smyth, M.J., et al. Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth. PLoS One 2009, 9, e6982.
-
(2009)
PLoS One
, vol.9
-
-
van der Most, R.G.1
Currie, A.J.2
Cleaver, A.L.3
Salmons, J.4
Nowak, A.K.5
Mahendran, S.6
Larma, I.7
Prosser, A.8
Robinson, B.W.9
Smyth, M.J.10
-
103
-
-
77951178310
-
Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice
-
Ramakrishnan, R.; Assudani, D.; Nagaraj, S.; Hunter, T.; Cho, H.I.; Antonia, S.; Altiok, S.; Celis, E.; Gabrilovich, D.I. Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice. J. Clin. Invest. 2010, 4, 1111-1124.
-
(2010)
J. Clin. Invest
, vol.4
, pp. 1111-1124
-
-
Ramakrishnan, R.1
Assudani, D.2
Nagaraj, S.3
Hunter, T.4
Cho, H.I.5
Antonia, S.6
Altiok, S.7
Celis, E.8
Gabrilovich, D.I.9
-
104
-
-
79960426821
-
Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors
-
Mattarollo, S.R.; Loi, S.; Duret, H.; Ma, Y.; Zitvogel, L.; Smyth, M.J. Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors. Cancer Res. 2011, 14, 4809-4820.
-
(2011)
Cancer Res
, vol.14
, pp. 4809-4820
-
-
Mattarollo, S.R.1
Loi, S.2
Duret, H.3
Ma, Y.4
Zitvogel, L.5
Smyth, M.J.6
-
105
-
-
79952716229
-
Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy
-
Ma, Y.; Aymeric, L.; Locher, C.; Mattarollo, S.R.; Delahaye, N.F.; Pereira, P.; Boucontet, L.; Apetoh, L.; Ghiringhelli, F.; Casares, N., et al. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J. Exp. Med. 2011, 3, 491-503.
-
(2011)
J. Exp. Med
, vol.3
, pp. 491-503
-
-
Ma, Y.1
Aymeric, L.2
Locher, C.3
Mattarollo, S.R.4
Delahaye, N.F.5
Pereira, P.6
Boucontet, L.7
Apetoh, L.8
Ghiringhelli, F.9
Casares, N.10
-
106
-
-
84867583274
-
Tumorinfiltrating lymphocytes predict response to chemotherapy in patients with advance non-small cell lung cancer
-
doi:10.1007/s00262-012-1231-7
-
Liu, H.; Zhang, T.; Ye, J.; Li, H.; Huang, J.; Li, X.; Wu, B.; Huang, X.; Hou, J. Tumorinfiltrating lymphocytes predict response to chemotherapy in patients with advance non-small cell lung cancer. Cancer Immunol. Immunother. 2012, doi:10.1007/s00262-012-1231-7.
-
(2012)
Cancer Immunol. Immunother
-
-
Liu, H.1
Zhang, T.2
Ye, J.3
Li, H.4
Huang, J.5
Li, X.6
Wu, B.7
Huang, X.8
Hou, J.9
-
107
-
-
62449250053
-
Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome
-
Gobert, M.; Treilleux, I.; Bendriss-Vermare, N.; Bachelot, T.; Goddard-Leon, S.; Arfi, V.; Biota, C.; Doffin, A.C.; Durand, I.; Olive, D., et al. Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome. Cancer Res. 2009, 5, 2000-2009.
-
(2009)
Cancer Res
, vol.5
, pp. 2000-2009
-
-
Gobert, M.1
Treilleux, I.2
Bendriss-Vermare, N.3
Bachelot, T.4
Goddard-Leon, S.5
Arfi, V.6
Biota, C.7
Doffin, A.C.8
Durand, I.9
Olive, D.10
-
108
-
-
34247261531
-
-
Bates, G.J.; Fox, S.B.; Han, C.; Leek, R.D.; Garcia, J.F.; Harris, A.L.; Banham, A.H. Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J. Clin. Oncol. 2006, 34, 5373-5380.
-
(2006)
Quantification of Regulatory T Cells Enables the Identification of High-risk Breast Cancer Patients and Those At Risk of Late Relapse
, vol.34
, pp. 5373-5380
-
-
Bates, G.J.1
Fox, S.B.2
Han, C.3
Leek, R.D.4
Garcia, J.F.5
Harris, A.L.6
Banham, A.H.7
-
109
-
-
79951815749
-
Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer
-
Tosolini, M.; Kirilovsky, A.; Mlecnik, B.; Fredriksen, T.; Mauger, S.; Bindea, G.; Berger, A.; Bruneval, P.; Fridman, W.H.; Pages, F., et al. Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. Cancer Res.2011, 4, 1263-1271.
-
(2011)
Cancer Res
, vol.4
, pp. 1263-1271
-
-
Tosolini, M.1
Kirilovsky, A.2
Mlecnik, B.3
Fredriksen, T.4
Mauger, S.5
Bindea, G.6
Berger, A.7
Bruneval, P.8
Fridman, W.H.9
Pages, F.10
-
110
-
-
67651160649
-
CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
-
Denardo, D.G.; Barreto, J.B.; Andreu, P.; Vasquez, L.; Tawfik, D.; Kolhatkar, N.; Coussens, L.M. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 2009, 2, 91-102.
-
(2009)
Cancer Cell
, vol.2
, pp. 91-102
-
-
Denardo, D.G.1
Barreto, J.B.2
Andreu, P.3
Vasquez, L.4
Tawfik, D.5
Kolhatkar, N.6
Coussens, L.M.7
-
111
-
-
0142219885
-
Thyroid cancer resistance to chemotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10
-
Stassi, G.; Todaro, M.; Zerilli, M.; Ricci-Vitiani, L.; di Liberto, D.; Patti, M.; Florena, A.; di Gaudio, F.; di Gesu, G.; de Maria, R. Thyroid cancer resistance to chemotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10. Cancer Res. 2003, 20, 6784-6790.
-
(2003)
Cancer Res
, vol.20
, pp. 6784-6790
-
-
Stassi, G.1
Todaro, M.2
Zerilli, M.3
Ricci-Vitiani, L.4
di Liberto, D.5
Patti, M.6
Florena, A.7
di Gaudio, F.8
di Gesu, G.9
de Maria, R.10
-
112
-
-
0142219885
-
Thyroid cancer resistance to chemotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10
-
Stassi, G.; Todaro, M.; Zerilli, M.; Ricci-Vitiani, L.; di Liberto, D.; Patti, M.; Florena, A.; di Gaudio, F.; di Gesu, G.; de Maria, R. Thyroid cancer resistance to chemotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10. Cancer Res. 2003, 20, 6784-6790.
-
(2003)
Cancer Res
, vol.20
, pp. 6784-6790
-
-
Stassi, G.1
Todaro, M.2
Zerilli, M.3
Ricci-Vitiani, L.4
di Liberto, D.5
Patti, M.6
Florena, A.7
di Gaudio, F.8
di Gesu, G.9
de Maria, R.10
-
113
-
-
77950196277
-
T(H)17 cells in tumour immunity and immunotherapy
-
Zou, W.; Restifo, N.P. T(H)17 cells in tumour immunity and immunotherapy. Nat. Rev. Immunol. 2010, 4, 248-256.
-
(2010)
Nat. Rev. Immunol
, vol.4
, pp. 248-256
-
-
Zou, W.1
Restifo, N.P.2
-
114
-
-
84858163275
-
Cytotoxic chemotherapy and CD4+ effector T cells: An emerging alliance for durable antitumor effects
-
doi:10.1155/2012/890178
-
Ding, Z.C.; Zhou, G. Cytotoxic chemotherapy and CD4+ effector T cells: An emerging alliance for durable antitumor effects. Clin. Dev. Immunol. 2012, doi:10.1155/2012/890178.
-
(2012)
Clin. Dev. Immunol
-
-
Ding, Z.C.1
Zhou, G.2
-
115
-
-
79951811209
-
Tumor-intrinsic and-extrinsic roles of c-Kit: Mast cells as the primary off-target of tyrosine kinase inhibitors
-
Pittoni, P.; Piconese, S.; Tripodo, C.; Colombo, M.P. Tumor-intrinsic and-extrinsic roles of c-Kit: Mast cells as the primary off-target of tyrosine kinase inhibitors. Oncogene 2011, 7, 757-769.
-
(2011)
Oncogene
, vol.7
, pp. 757-769
-
-
Pittoni, P.1
Piconese, S.2
Tripodo, C.3
Colombo, M.P.4
-
116
-
-
77957280758
-
Mast cells are novel independent prognostic markers in prostate cancer and represent a target for therapy
-
Johansson, A.; Rudolfsson, S.; Hammarsten, P.; Halin, S.; Pietras, K.; Jones, J.; Stattin, P.; Egevad, L.; Granfors, T.; Wikstrom, P., et al. Mast cells are novel independent prognostic markers in prostate cancer and represent a target for therapy. Am. J. Pathol. 2010, 2, 1031-1041.
-
(2010)
Am. J. Pathol
, vol.2
, pp. 1031-1041
-
-
Johansson, A.1
Rudolfsson, S.2
Hammarsten, P.3
Halin, S.4
Pietras, K.5
Jones, J.6
Stattin, P.7
Egevad, L.8
Granfors, T.9
Wikstrom, P.10
-
117
-
-
84857201114
-
The dark side of mast cell-targeted therapy in prostate cancer
-
Pittoni, P.; Colombo, M.P. The dark side of mast cell-targeted therapy in prostate cancer. Cancer Res. 2012, 4, 831-835.
-
(2012)
Cancer Res
, vol.4
, pp. 831-835
-
-
Pittoni, P.1
Colombo, M.P.2
-
118
-
-
0142103807
-
Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization
-
Iyengar, P.; Combs, T.P.; Shah, S.J.; Gouon-Evans, V.; Pollard, J.W.; Albanese, C.; Flanagan, L.; Tenniswood, M.P.; Guha, C.; Lisanti, M.P., et al. Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization. Oncogene 2003, 41, 6408-6423.
-
(2003)
Oncogene
, vol.41
, pp. 6408-6423
-
-
Iyengar, P.1
Combs, T.P.2
Shah, S.J.3
Gouon-Evans, V.4
Pollard, J.W.5
Albanese, C.6
Flanagan, L.7
Tenniswood, M.P.8
Guha, C.9
Lisanti, M.P.10
-
119
-
-
70350231608
-
Adipocytes impair leukemia treatment in mice
-
Behan, J.W.; Yun, J.P.; Proektor, M.P.; Ehsanipour, E.A.; Arutyunyan, A.; Moses, A.S.; Avramis, V.I.; Louie, S.G.; Butturini, A.; Heisterkamp, N., et al. Adipocytes impair leukemia treatment in mice. Cancer Res. 2009, 19, 7867-7874.
-
(2009)
Cancer Res
, vol.19
, pp. 7867-7874
-
-
Behan, J.W.1
Yun, J.P.2
Proektor, M.P.3
Ehsanipour, E.A.4
Arutyunyan, A.5
Moses, A.S.6
Avramis, V.I.7
Louie, S.G.8
Butturini, A.9
Heisterkamp, N.10
-
120
-
-
79960555932
-
Cancer-associated adipocytes promotes breast tumor radioresistance
-
Bochet, L.; Meulle, A.; Imbert, S.; Salles, B.; Valet, P.; Muller, C. Cancer-associated adipocytes promotes breast tumor radioresistance. Biochem. Biophys. Res. Commun. 2011, 1, 102-106.
-
(2011)
Biochem. Biophys. Res. Commun
, vol.1
, pp. 102-106
-
-
Bochet, L.1
Meulle, A.2
Imbert, S.3
Salles, B.4
Valet, P.5
Muller, C.6
-
121
-
-
77954818666
-
MicroRNA and drug resistance
-
Ma, J.; Dong, C.; Ji, C. MicroRNA and drug resistance. Cancer Gene Ther. 2010, 8, 523-531.
-
(2010)
Cancer Gene Ther
, vol.8
, pp. 523-531
-
-
Ma, J.1
Dong, C.2
Ji, C.3
-
122
-
-
56449108015
-
Role of microRNAs in drug-resistant ovarian cancer cells
-
Sorrentino, A.; Liu, C.G.; Addario, A.; Peschle, C.; Scambia, G.; Ferlini, C. Role of microRNAs in drug-resistant ovarian cancer cells. Gynecol. Oncol 2008, 3, 478-486.
-
(2008)
Gynecol. Oncol
, vol.3
, pp. 478-486
-
-
Sorrentino, A.1
Liu, C.G.2
Addario, A.3
Peschle, C.4
Scambia, G.5
Ferlini, C.6
-
123
-
-
84859810024
-
Circulating MiR-125b as a marker predicting chemoresistance in breast cancer
-
Wang, H.; Tan, G.; Dong, L.; Cheng, L.; Li, K.; Wang, Z.; Luo, H. Circulating MiR-125b as a marker predicting chemoresistance in breast cancer. PLoS One 2012, 4, e34210.
-
(2012)
PLoS One
, vol.4
-
-
Wang, H.1
Tan, G.2
Dong, L.3
Cheng, L.4
Li, K.5
Wang, Z.6
Luo, H.7
-
124
-
-
83755205900
-
Plasma miR-221 as a predictive biomarker for chemoresistance in breast cancer patients who previously received neoadjuvant chemotherapy
-
Zhao, R.; Wu, J.; Jia, W.; Gong, C.; Yu, F.; Ren, Z.; Chen, K.; He, J.; Su, F. Plasma miR-221 as a predictive biomarker for chemoresistance in breast cancer patients who previously received neoadjuvant chemotherapy. Onkologie 2011, 12, 675-680.
-
(2011)
Onkologie
, vol.12
, pp. 675-680
-
-
Zhao, R.1
Wu, J.2
Jia, W.3
Gong, C.4
Yu, F.5
Ren, Z.6
Chen, K.7
He, J.8
Su, F.9
-
125
-
-
84860755726
-
The miRNA-17 approximately 92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation
-
Rao, E.; Jiang, C.; Ji, M.; Huang, X.; Iqbal, J.; Lenz, G.; Wright, G.; Staudt, L.M.; Zhao, Y.; McKeithan, T.W., et al. The miRNA-17 approximately 92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. Leukemia 2012, 5, 1064-1072.
-
(2012)
Leukemia
, vol.5
, pp. 1064-1072
-
-
Rao, E.1
Jiang, C.2
Ji, M.3
Huang, X.4
Iqbal, J.5
Lenz, G.6
Wright, G.7
Staudt, L.M.8
Zhao, Y.9
McKeithan, T.W.10
-
126
-
-
79955519053
-
Over expression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway
-
Hamano, R.; Miyata, H.; Yamasaki, M.; Kurokawa, Y.; Hara, J.; Moon, J.H.; Nakajima, K.; Takiguchi, S.; Fujiwara, Y.; Mori, M., et al. Over expression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway. Clin. Cancer Res. 2011, 9, 3029-3038.
-
(2011)
Clin. Cancer Res
, vol.9
, pp. 3029-3038
-
-
Hamano, R.1
Miyata, H.2
Yamasaki, M.3
Kurokawa, Y.4
Hara, J.5
Moon, J.H.6
Nakajima, K.7
Takiguchi, S.8
Fujiwara, Y.9
Mori, M.10
-
127
-
-
77952944048
-
MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer
-
Kong, W.; He, L.; Coppola, M.; Guo, J.; Esposito, N.N.; Coppola, D.; Cheng, J.Q. MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer. J. Biol. Chem. 2010, 23, 17869-17879.
-
(2010)
J. Biol. Chem
, vol.23
, pp. 17869-17879
-
-
Kong, W.1
He, L.2
Coppola, M.3
Guo, J.4
Esposito, N.N.5
Coppola, D.6
Cheng, J.Q.7
-
128
-
-
84855781227
-
Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells
-
Bourguignon, L.Y.; Earle, C.; Wong, G.; Spevak, C.C.; Krueger, K. Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells. Oncogene 2012, 2, 149-160.
-
(2012)
Oncogene
, vol.2
, pp. 149-160
-
-
Bourguignon, L.Y.1
Earle, C.2
Wong, G.3
Spevak, C.C.4
Krueger, K.5
-
129
-
-
78049442966
-
The cellular response to hypoxia: Tuning the system with micro RNAs
-
Loscalzo, J. The cellular response to hypoxia: Tuning the system with micro RNAs. J. Clin. Invest. 2010, 11, 3815-3817.
-
(2010)
J. Clin. Invest
, vol.11
, pp. 3815-3817
-
-
Loscalzo, J.1
-
130
-
-
33846941188
-
High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma
-
doi:10.1186/1476-4598-6-5
-
Hebert, C.; Norris, K.; Scheper, M.A.; Nikitakis, N.; Sauk, J.J. High mobility group A2 is a target for miRNA-98 in head and neck squamous cell carcinoma. Mol. Cancer 2007, 6, doi:10.1186/1476-4598-6-5.
-
(2007)
Mol. Cancer
, pp. 6
-
-
Hebert, C.1
Norris, K.2
Scheper, M.A.3
Nikitakis, N.4
Sauk, J.J.5
-
131
-
-
84858590826
-
Accessories to the crime: Functions of cells recruited to the tumor microenvironment
-
Hanahan, D.; Coussens, L.M. Accessories to the crime: Functions of cells recruited to the tumor microenvironment. Cancer Cell 2012, 3, 309-322.
-
(2012)
Cancer Cell
, vol.3
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
132
-
-
80053442440
-
Lymph node stromal cells enhance drug-resistant colon cancer cell tumor formation through SDF-1alpha/CXCR4 paracrine signaling
-
Margolin, D.A.; Silinsky, J.; Grimes, C.; Spencer, N.; Aycock, M.; Green, H.; Cordova, J.; Davis, N.K.; Driscoll, T.; Li, L. Lymph node stromal cells enhance drug-resistant colon cancer cell tumor formation through SDF-1alpha/CXCR4 paracrine signaling. Neoplasia. 2011, 9, 874-886.
-
(2011)
Neoplasia
, vol.9
, pp. 874-886
-
-
Margolin, D.A.1
Silinsky, J.2
Grimes, C.3
Spencer, N.4
Aycock, M.5
Green, H.6
Cordova, J.7
Davis, N.K.8
Driscoll, T.9
Li, L.10
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