Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant

Gastroenterology

Volumn 128, Issue 2, 2005, Pages 361-375

  Tu, Shui Ping ^a,b   Cui, Jian Tao ^b   Liston, Peter ^c   Huajiang, Xiao ^a,b   Xu, Ruian ^b   Lin, Marie C M ^b   Zhu, Yan Bo ^a   Zou, Bing ^a   Ng, Samuel S M ^b   Jiang, Shi Hu ^a   Xia, Harry H X ^b   Wong, Wai Man ^b   Chan, Annie O O ^b   Yuen, Man Fung ^b   Lam, Shiu Kum ^b   Kung, Hsiang Fu ^b   Wong, Benjamin C Y ^b  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CISPLATIN; CYSTEINE; FLUOROURACIL; MUTANT PROTEIN; PARVOVIRUS VECTOR; SURVIVIN; ALANINE; BIRC5 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; TUMOR PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG SENSITIZATION; EMBRYO; EXPRESSION VECTOR; FEMALE; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOSIS; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; VIRUS RECOMBINANT; XENOGRAFT; ADENO ASSOCIATED VIRUS; AMINO ACID SUBSTITUTION; CELL DIVISION; COLON TUMOR; GENE VECTOR; GENETICS; METHODOLOGY; MISSENSE MUTATION; PATHOLOGY; TUMOR CELL LINE;

ALANINE; AMINO ACID SUBSTITUTION; APOPTOSIS; CELL DIVISION; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYSTEINE; DEPENDOVIRUS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; MUTATION, MISSENSE; NEOPLASM PROTEINS;

EID: 14944359615     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2004.11.058     Document Type: Article

References (46)

1. G. Ambrosini, C. Adida, D.C. Altieri A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma Nat Med 3 1997 917 921
2. F. Li, G. Ambrosini, E.Y. Chu, J. Plescia, S. Tognin, P.C. Marchisio, D.C. Altieri Control of apoptosis and mitotic spindle checkpoint by survivin Nature 396 1998 580 584
3. I. Tamm, Y. Wang, E. Sausville, D.A. Scudiero, N. Vigna, T. Oltersdorf, J.C. Reed IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs Cancer Res 58 1998 5315 5320
4. D. Grossman, P.J. Kim, O.P. Blanc-Brude, D.E. Brash, S. Tognin, P.C. Marchisio, D.C. Altieri Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53 J Clin Invest 108 2001 991 999
5. A. Suzuki, M. Hayashida, T. Ito, H. Kawano, T. Nakano, M. Miura, K. Akahane, K. Shiraki Survivin initiates cell cycle entry by the competitive interaction with Cdk4/p16(INK4a) and Cdk2/cyclin E complex activation Oncogene 19 2000 3225 3234
6. H.S. Swana, D. Grossman, J.N. Anthony, R.M. Weiss, D.C. Altieri Tumor content of the antiapoptosis molecule survivin and recurrence of bladder cancer N Engl J Med 341 1999 452 453
7. J. Kato, Y. Kuwabara, M. Mitani, N. Shinoda, A. Sato, T. Toyama, A. Mitsui, T. Nishiwaki, S. Moriyama, J. Kudo, Y. Fujii Expression of survivin in esophageal cancer correlation with the prognosis and response to chemotherapy Int J Cancer 95 2001 92 95
8. R. Bao, D.C. Connolly, M. Murphy, J. Green, J.K. Weinstein, D.A. Pisarcik, T.C. Hamilton Activation of cancer-specific gene expression by the survivin promoter J Natl Cancer Inst 94 2002 522 528
9. L. Yang, Z. Cao, H. Yan, W.C. Wood Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells implication for cancer specific therapy Cancer Res 63 2003 6815 6824
10. D.S. O'Connor, S. Daniel, S. Jeffrey, S. Schechner, C. Adida, M. Mesri, A.L. Rothermel, F.Z. Li, A.K. Nath, J.S. Pober, D.C. Altieri Control of apoptosis during angiogenesis by survivin expression in endothelial cells Am J Pathol 156 2000 393 398
11. J. Tran, J. Rak, C. Sheehan, S.D. Saibil, E. LaCasse, R.G. Korneluk, R.S. Kerbel Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells Biochem Biophys Res Commun 264 1999 781 788
12. A. Papapetropoulos, D. Fulton, K. Mahboubi, R.G. Kalb, D.S. O'Connor, F. Li, D.C. Altieri, W.C. Sessa Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/Survivin pathway J Biol Chem 275 2000 9102 9105
13. M. Mesri, M. Morales-Ruiz, E.J. Ackermann, C.F. Bennett, J.S. Pober, W.C. Sessa, D.C. Altieri Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting Am J Pathol 158 2001 1757 1765
14. F. Li, E.J. Ackermann, C.F. Bennett, A.L. Rothetmel, J. Plescia, S. Tognin, A. Villa, P.C. Marchisio, D.C. Altieri Pleiotropic cell-division defects and apoptosis induced by interference with survivin function Nat Cell Biol 1 1999 461 466
15. N.R. Wall, D.S. O'Connor, J. Plescia, Y. Pommier, D.C. Altieri Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis Cancer Res 63 2003 230 235
16. D. Grossman, P.J. Kim, J.S. Schechner, D.C. Altieri Inhibition of melanoma tumor growth in vivo by survivin targeting Proc Natl Acad Sci U S A 98 2001 635 640
17. T. Yamamoto, Y. Manome, M. Nakamura, N. Tanigawa Down-regulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer Eur J Cancer 38 2002 2316 2324
18. S. Wittmann, P. Bali, S. Donapaty, R. Nimmanapalli, F. Guo, H. Yamaguchi, M. Huang, R. Jove, H.G. Wang, K. Bhalla Flavopiridol down-regulates antiapoptotic proteins and sensitizes human breast cancer cells to epothilone B-induced apoptosis Cancer Res 63 2003 93 99
19. E.M. Conway, S. Pollefeyt, M. Steiner-Mosonyi, W. Luo, A. Devriese, F. Lupu, F. Bono, N. Leducq, F. Dol, P. Schaeffer, D. Collen, J.M. Herbert Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways Gastroenterology 123 2002 619 631
20. S.P. Tu, X.H. Jiang, M.C. Lin, J.T. Cui, Y. Yang, C.T. Lum, B. Zou, Y.B. Zhu, S.H. Jiang, W.M. Wong, A.O. Chan, M.F. Yuen, S.K. Lam, H.F. Kung, B.C. Wong Suppression of survivin expression inhibits in vivo tumorigenicity and angiogenesis in gastric cancer Cancer Res 63 2003 7724 7732
21. M. Mesri, N.R. Wall, J. Li, R.W. Kim, D.C. Altieri Cancer gene therapy using a survivin mutant adenovirus J Clin Invest 108 2001 981 990
22. J.R. Kanwar, W.P. Shen, R.K. Kanwar, R.W. Berg, G.W. Krissansen Effects of survivin antagonists on growth of established tumors and b7-1 immunogene therapy J Natl Cancer Inst 93 2001 1541 1552
23. C. Mah, B.J. Byrne, T.R. Flotte Virus-based gene delivery systems Clin Pharmacokinet 41 2002 901 911
24. P.J. Carter, R.J. Samulski Adeno-associated viral vectors as gene delivery vehicles Int J Mol Med 6 2000 17 27
25. M.A. Kay, C.S. Manno, M.V. Ragni Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector Nat Genet 24 2000 17 27
26. S. Ponnazhagan, D.T. Curiel, D.R. Shaw, R.D. Alvarez, G.P. Siegal Adeno-associated virus for cancer gene therapy Cancer Res 61 2001 6313 6321
27. A.M. Davidoff, A.C. Nathwani, W.W. Spurbeck, C.Y. Ng, J. Zhou, E.F. Vanin rAAV-mediated long-term liver-generated expression of an angiogenesis inhibitor can restrict renal tumor growth in mice Cancer Res 62 2002 3077 3083
28. P.Q. Enger, F. Thorsen, P.E. Lønning, R. Bjerkvig, F. Hoover Adeno-associated viral vectors penetrate human solid tumor tissue in vivo more effectively than adenoviral vectors Hum Gene Ther 13 2002 1115 1125
29. H. Kawasaki, D.C. Altieri, C.D. Lu, M. Toyoda, T. Tenjo, N. Tanigawa Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer Cancer Res 58 1998 5071 5074
30. A.I. Sarela, N. Scott, J. Ramsdale, A.F. Markham, P.J. Guillou Immunohistochemical detection of the anti-apoptosis protein, survivin, predicts survival after curative resection of stage II colorectal carcinomas Ann Surg Oncol 8 2001 305 310
31. R. Gianani, E. Jarboe, D. Orlicky, M. Frost, J. Bobak, R. Lehner, K.R. Shroyer Expression of survivin in normal, hyperplastic, and neoplastic colonic mucosa Hum Pathol 32 2001 119 125
32. H. Kawasaki, M. Toyoda, H. Shinohara, J. Okuda, I. Watanabe, T. Yamamoto, K. Tanaka, T. Tenjo, N. Tanigawa Expression of survivin correlates with apoptosis, proliferation, and angiogenesis during human colorectal tumorigenesis Cancer 91 2001 2026 2032
33. M.J. During, C.W. Symes, P.A. Lawlor, J. Lin, J. Dunning, H.L. Fitzsimons, D. Poulsen, P. Leone, R. Xu, B.L. Dicker, J. Lipski, D. Young An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy Science 287 2000 1453 1460
34. R. Xu, X.Y. Sun, L.Y. Tse, Hu Li, P.C. Chan, S. Xu, W.D. Xiao, H.F. Kung, G.W. Krissansen, S.T. Fan Long-term expression of angiostatin suppresses metastatic liver cancer in mice Hepatology 37 2003 1451 1460
35. K.R. Dumon, H. Ishii, A. Vecchione, F. Trapasso, G. Baldassarre, F. Chakrani, T. Druck, E.F. Rosato, N.N. Williams, R. Baffa, M.J. During, K. Huebner, C.M. Croce Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer Cancer Res 61 2001 4827 4836
36. B.C. Wong, X.H. Jiang, M.C. Lin, S.P. Tu, J.T. Cui, S.H. Jiang, W.M. Wong, M.F. Yuen, S.K. Lam, H.F. Kung Cyclooxygenase-2 inhibitor (SC-236) suppresses activator protein-1 through c-Jun NH2-terminal kinase Gastroenterology 126 2004 136 147
37. A. Giatromanolaki, M.I. Koukourakis, D. Theodossiou, K. Barbatis, K. O'Byrne, A.L. Harris, K.C. Gatter Comparative evaluation of angiogenesis assessment with anti-factor-VIII and anti-CD31 immunostaining in non-small cell lung cancer Clin Cancer Res 3 1997 2485 2492
38. C.H. Baker, D. Kedar, M.F. McCarty, R. Tsan, K.L. Weber, C.D. Bucana, I.J. Fidler Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas Am J Pathol 161 2002 929 938
39. A.G. Uren, L. Wong, M. Pakusch, K.J. Fowler, F.J. Burrows, D.L. Vaux, K.H. Choo Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype Curr Biol 10 2000 1319 1328
40. M.J. Kallio, M. Nieminen, J.E. Eriksson Human inhibitor of apoptosis protein (IAP) survivin participates in regulation of chromosome segregation and mitotic exit FASEB J 15 2001 2721 2723
41. S.M. Lens, R.M. Wolthuis, R. Klompmaker, J. Kauw, R. Agami, T. Brummelkamp, G. Kops, R.H. Medema Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension EMBO J 22 2003 2934 2947
42. E. Beltrami, J. Plescia, J.C. Wilkinson, C.S. Duckett, D.C. Altieri Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis J Biol Chem 279 2004 2077 2084
43. I.B. Roninson, E.V. Broude, B.D. Chang If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells Drug Resist Update 4 2001 303 313
44. A. Temme, M. Rieger, F. Reber, D. Lindemann, B. Weigle, P. Diestelkoetter-Bachert, G. Ehninger, M. Tatsuka, Y. Terada, E.P. Rieber Localization, dynamics, and function of survivin revealed by expression of functional SurvivinDsRed fusion proteins in the living cell Mol Biol Cell 14 2003 78 92
45. A.M. Davidoff, A.C. Nathwani, W.W. Spurbeck, C.Y. Ng, J. Zhou, E.F. Vanin rAAV-mediated long-term liver-generated expression of an angiogenesis inhibitor can restrict renal tumor growth in mice Cancer Res 62 2002 3077 3083
46. H.I. Ma, P. Guo, J. Li, S.Z. Lin, Y.H. Chiang, X. Xiao, S.Y. Cheng Suppression of intracranial human glioma growth after intramuscular administration of an adeno-associated viral vector expressing angiostatin Cancer Res 62 2002 756 763