Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy

Cancer Research

Volumn 71, Issue 16, 2011, Pages 5512-5521

  Yang, Fei ^a,d   Tang, Ximing ^a   Riquelme, Erick ^a   Behrens, Carmen ^a   Nilsson, Monique B ^a   Giri, Uma ^a   Varella Garcia, Marileila ^c   Byers, Lauren A ^a   Lin, Heather Y ^a   Wang, Jing ^a   Raso, Maria G ^a   Girard, Luc ^b   Coombes, Kevin ^a   Lee, J Jack ^a   Herbst, Roy S ^a   Minna, John D ^b   Heymach, John V ^a   Wistuba, Ignacio I ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c UNIVERSITY OF COLORADO CANCER CENTER   (United States)

^d FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; CISPLATIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PLATINUM DERIVATIVE; VASCULOTROPIN RECEPTOR 2;

ADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY; ANGIOGENESIS; ARTICLE; CANCER SURVIVAL; CELL LEVEL; CELL MIGRATION; CHEMOSENSITIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; COPY NUMBER VARIATION; CYTOTOXICITY; DRUG RESISTANCE; EXON; GENE DOSAGE; GENE MUTATION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; KDR GENE; LUNG NON SMALL CELL CANCER; MOLECULAR DYNAMICS; MORTALITY; MUTATIONAL ANALYSIS; ONCOGENE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL TIME;

CARCINOMA, NON-SMALL-CELL LUNG; CHEMOTHERAPY, ADJUVANT; DRUG RESISTANCE, NEOPLASM; GENE DOSAGE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LUNG NEOPLASMS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SURVIVAL RATE; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 80051676156     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-2614     Document Type: Article

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