메뉴 건너뛰기




Volumn 4, Issue 8, 2012, Pages 705-718

Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes

Author keywords

Embryogenesis; Igf2; P53; Tumour predisposition; X linked

Indexed keywords

PROTEIN P53; SOMATOMEDIN B;

EID: 84864820659     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201101105     Document Type: Article
Times cited : (28)

References (80)
  • 3
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker J, Liu JP, Robertson EJ, Efstratiadis A (1993) Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75: 73-82
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 5
    • 8844278362 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
    • Bond GL, Hu W, Bond EE, Robins H, Lutzker SG, Arva NC, Bargonetti J, Bartel F, Taubert H, Wuerl P, et al (2004) A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 119: 591-602
    • (2004) Cell , vol.119 , pp. 591-602
    • Bond, G.L.1    Hu, W.2    Bond, E.E.3    Robins, H.4    Lutzker, S.G.5    Arva, N.C.6    Bargonetti, J.7    Bartel, F.8    Taubert, H.9    Wuerl, P.10
  • 8
    • 48449101433 scopus 로고    scopus 로고
    • p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
    • Budanov AV, Karin M (2008) p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell 134: 451-460
    • (2008) Cell , vol.134 , pp. 451-460
    • Budanov, A.V.1    Karin, M.2
  • 9
    • 0034773185 scopus 로고    scopus 로고
    • Cell survival and proliferation are modified by insulin-like growth factor 2 between days 9 and 10 of mouse gestation
    • Burns JL, Hassan AB (2001) Cell survival and proliferation are modified by insulin-like growth factor 2 between days 9 and 10 of mouse gestation. Development 128: 3819-3830
    • (2001) Development , vol.128 , pp. 3819-3830
    • Burns, J.L.1    Hassan, A.B.2
  • 10
    • 33847271696 scopus 로고    scopus 로고
    • The imprinted H19 noncoding RNA is a primary microRNA precursor
    • Cai X, Cullen BR (2007) The imprinted H19 noncoding RNA is a primary microRNA precursor. RNA 13: 313-316
    • (2007) RNA , vol.13 , pp. 313-316
    • Cai, X.1    Cullen, B.R.2
  • 11
    • 34147128806 scopus 로고    scopus 로고
    • Zfx: at the crossroads of survival and self-renewal
    • Cellot S, Sauvageau G (2007) Zfx: at the crossroads of survival and self-renewal. Cell 129: 239-241
    • (2007) Cell , vol.129 , pp. 239-241
    • Cellot, S.1    Sauvageau, G.2
  • 12
    • 66149141021 scopus 로고    scopus 로고
    • PTEN and the PI3-kinase pathway in cancer
    • Chalhoub N, Baker SJ (2009) PTEN and the PI3-kinase pathway in cancer. Annu Rev Pathol 4: 127-150
    • (2009) Annu Rev Pathol , vol.4 , pp. 127-150
    • Chalhoub, N.1    Baker, S.J.2
  • 13
    • 0028356419 scopus 로고
    • A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis
    • Christofori G, Naik P, Hanahan D (1994) A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis. Nature 369: 414-418
    • (1994) Nature , vol.369 , pp. 414-418
    • Christofori, G.1    Naik, P.2    Hanahan, D.3
  • 14
    • 0029006470 scopus 로고
    • Deregulation of both imprinted and expressed alleles of the insulin-like growth factor 2 gene during beta-cell tumorigenesis
    • Christofori G, Naik P, Hanahan D (1995) Deregulation of both imprinted and expressed alleles of the insulin-like growth factor 2 gene during beta-cell tumorigenesis. Nat Genet 10: 196-201
    • (1995) Nat Genet , vol.10 , pp. 196-201
    • Christofori, G.1    Naik, P.2    Hanahan, D.3
  • 17
    • 0025320906 scopus 로고
    • A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting
    • DeChiara TM, Efstratiadis A, Robertson EJ (1990) A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345: 78-80
    • (1990) Nature , vol.345 , pp. 78-80
    • DeChiara, T.M.1    Efstratiadis, A.2    Robertson, E.J.3
  • 18
    • 0025967857 scopus 로고
    • Parental imprinting of the mouse insulin-like growth factor II gene
    • DeChiara TM, Robertson EJ, Efstratiadis A (1991) Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64: 849-859
    • (1991) Cell , vol.64 , pp. 849-859
    • DeChiara, T.M.1    Robertson, E.J.2    Efstratiadis, A.3
  • 19
    • 0036260527 scopus 로고    scopus 로고
    • Does p53 affect organismal aging
    • Donehower LA (2002) Does p53 affect organismal aging? J Cell Physiol 192: 23-33
    • (2002) J Cell Physiol , vol.192 , pp. 23-33
    • Donehower, L.A.1
  • 20
    • 67649332816 scopus 로고    scopus 로고
    • Longevity regulation in flies: a role for p53
    • Donehower LA (2009) Longevity regulation in flies: a role for p53. Aging (Albany NY) 1: 6-8
    • (2009) Aging (Albany NY) , vol.1 , pp. 6-8
    • Donehower, L.A.1
  • 22
    • 46249088370 scopus 로고    scopus 로고
    • lumi: a pipeline for processing Illumina microarray
    • Du P, Kibbe WA, Lin SM (2008) lumi: a pipeline for processing Illumina microarray. Bioinformatics 24: 1547-1548
    • (2008) Bioinformatics , vol.24 , pp. 1547-1548
    • Du, P.1    Kibbe, W.A.2    Lin, S.M.3
  • 25
    • 77954310492 scopus 로고    scopus 로고
    • The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein
    • Feng Z, Levine AJ (2010) The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein. Trends Cell Biol 20: 427-434
    • (2010) Trends Cell Biol , vol.20 , pp. 427-434
    • Feng, Z.1    Levine, A.J.2
  • 26
    • 3142545770 scopus 로고    scopus 로고
    • DNA damage induces p53-dependent BRCA1 nuclear export
    • Feng Z, Kachnic L, Zhang J, Powell SN, Xia F (2004) DNA damage induces p53-dependent BRCA1 nuclear export. J Biol Chem 279: 28574-28584
    • (2004) J Biol Chem , vol.279 , pp. 28574-28584
    • Feng, Z.1    Kachnic, L.2    Zhang, J.3    Powell, S.N.4    Xia, F.5
  • 27
    • 34248194200 scopus 로고    scopus 로고
    • The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways
    • Feng Z, Hu W, de Stanchina E, Teresky AK, Jin S, Lowe S, Levine AJ (2007) The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Res 67: 3043-33053
    • (2007) Cancer Res , vol.67 , pp. 3043-33053
    • Feng, Z.1    Hu, W.2    de Stanchina, E.3    Teresky, A.K.4    Jin, S.5    Lowe, S.6    Levine, A.J.7
  • 32
    • 0037336348 scopus 로고    scopus 로고
    • Mannose 6-phosphate receptors: new twists in the tale
    • Ghosh P, Dahms NM, Kornfeld S (2003) Mannose 6-phosphate receptors: new twists in the tale. Nat Rev Mol Cell Biol 4: 202-212
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 202-212
    • Ghosh, P.1    Dahms, N.M.2    Kornfeld, S.3
  • 33
    • 33751084057 scopus 로고    scopus 로고
    • Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling
    • Grimberg A, Coleman CM, Shi Z, Burns TF, MacLachlan TK, Wang W, El-Deiry WS (2006) Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling. Cancer Biol Ther 5: 1408-1414
    • (2006) Cancer Biol Ther , vol.5 , pp. 1408-1414
    • Grimberg, A.1    Coleman, C.M.2    Shi, Z.3    Burns, T.F.4    MacLachlan, T.K.5    Wang, W.6    El-Deiry, W.S.7
  • 34
    • 0027226306 scopus 로고
    • Genetic background alters the spectrum of tumors that develop in p53-deficient mice
    • Harvey M, McArthur MJ, Montgomery CA, Jr., Bradley A, Donehower LA (1993) Genetic background alters the spectrum of tumors that develop in p53-deficient mice. FASEB J 7: 938-943
    • (1993) FASEB J , vol.7 , pp. 938-943
    • Harvey, M.1    McArthur, M.J.2    Montgomery Jr, C.A.3    Bradley, A.4    Donehower, L.A.5
  • 35
    • 0034652480 scopus 로고    scopus 로고
    • Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice
    • Hassan AB, Howell JA (2000) Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice. Cancer Res 60: 1070-1076
    • (2000) Cancer Res , vol.60 , pp. 1070-1076
    • Hassan, A.B.1    Howell, J.A.2
  • 36
    • 69949168092 scopus 로고    scopus 로고
    • Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression
    • Hinkal G, Parikh N, Donehower LA (2009) Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression. PLoS ONE 4: e6654
    • (2009) PLoS ONE , vol.4
    • Hinkal, G.1    Parikh, N.2    Donehower, L.A.3
  • 37
    • 67651152911 scopus 로고    scopus 로고
    • Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors
    • Ho L, Stojanovski A, Whetstone H, Wei QX, Mau E, Wunder JS, Alman B (2009) Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors. Cancer Cell 16: 126-1136
    • (2009) Cancer Cell , vol.16 , pp. 126-1136
    • Ho, L.1    Stojanovski, A.2    Whetstone, H.3    Wei, Q.X.4    Mau, E.5    Wunder, J.S.6    Alman, B.7
  • 41
    • 0034601434 scopus 로고    scopus 로고
    • Activation of the insulin-like growth factor II transcription by aflatoxin B1 induced p53 mutant 249 is caused by activation of transcription complexes; implications for a gain-of-function during the formation of hepatocellular carcinoma
    • Lee YI, Lee S, Das GC, Park US, Park SM (2000) Activation of the insulin-like growth factor II transcription by aflatoxin B1 induced p53 mutant 249 is caused by activation of transcription complexes; implications for a gain-of-function during the formation of hepatocellular carcinoma. Oncogene 19: 3717-3726
    • (2000) Oncogene , vol.19 , pp. 3717-3726
    • Lee, Y.I.1    Lee, S.2    Das, G.C.3    Park, U.S.4    Park, S.M.5
  • 44
    • 0036559535 scopus 로고    scopus 로고
    • Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis
    • Lopez T, Hanahan D (2002) Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 1: 339-353
    • (2002) Cancer Cell , vol.1 , pp. 339-353
    • Lopez, T.1    Hanahan, D.2
  • 46
    • 80053022230 scopus 로고    scopus 로고
    • Li-fraumeni syndrome
    • Malkin D (2011) Li-fraumeni syndrome. Genes Cancer 2: 475-484
    • (2011) Genes Cancer , vol.2 , pp. 475-484
    • Malkin, D.1
  • 47
    • 77449101168 scopus 로고    scopus 로고
    • Mdm2-mediated ubiquitylation: p53 and beyond
    • Marine JC, Lozano G (2010) Mdm2-mediated ubiquitylation: p53 and beyond. Cell Death Differ 17: 93-102
    • (2010) Cell Death Differ , vol.17 , pp. 93-102
    • Marine, J.C.1    Lozano, G.2
  • 48
    • 33845611951 scopus 로고    scopus 로고
    • Modeling the therapeutic efficacy of p53 restoration in tumors
    • Martins CP, Brown-Swigart L, Evan GI (2006) Modeling the therapeutic efficacy of p53 restoration in tumors. Cell 127: 1323-1334
    • (2006) Cell , vol.127 , pp. 1323-1334
    • Martins, C.P.1    Brown-Swigart, L.2    Evan, G.I.3
  • 49
    • 0035949588 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
    • Mayo LD, Donner DB (2001) A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc Natl Acad Sci USA 98: 11598-11603
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11598-11603
    • Mayo, L.D.1    Donner, D.B.2
  • 53
    • 0036258111 scopus 로고    scopus 로고
    • The IARC TP53 database: new online mutation analysis and recommendations to users
    • Olivier M, Eeles R, Hollstein M, Khan MA, Harris CC, Hainaut P (2002) The IARC TP53 database: new online mutation analysis and recommendations to users. Hum Mutat 19: 607-614
    • (2002) Hum Mutat , vol.19 , pp. 607-614
    • Olivier, M.1    Eeles, R.2    Hollstein, M.3    Khan, M.A.4    Harris, C.C.5    Hainaut, P.6
  • 54
    • 0029956442 scopus 로고    scopus 로고
    • DNA hypomethylation can activate Xist expression and silence X-linked genes
    • Panning B, Jaenisch R (1996) DNA hypomethylation can activate Xist expression and silence X-linked genes. Genes Dev 10: 1991-2002
    • (1996) Genes Dev , vol.10 , pp. 1991-2002
    • Panning, B.1    Jaenisch, R.2
  • 55
    • 23044469636 scopus 로고    scopus 로고
    • Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development
    • Park IY, Sohn BH, Choo JH, Joe CO, Seong JK, Lee YI, Chung JH (2005) Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development. J Cell Biochem 94: 585-596
    • (2005) J Cell Biochem , vol.94 , pp. 585-596
    • Park, I.Y.1    Sohn, B.H.2    Choo, J.H.3    Joe, C.O.4    Seong, J.K.5    Lee, Y.I.6    Chung, J.H.7
  • 56
    • 0142250909 scopus 로고    scopus 로고
    • p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding
    • Peterson EJ, Bogler O, Taylor SM (2003) p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding. Cancer Res 63: 6579-6582
    • (2003) Cancer Res , vol.63 , pp. 6579-6582
    • Peterson, E.J.1    Bogler, O.2    Taylor, S.M.3
  • 59
    • 0038141338 scopus 로고    scopus 로고
    • Fibronectin requirement in branching morphogenesis
    • Sakai T, Larsen M, Yamada KM (2003) Fibronectin requirement in branching morphogenesis. Nature 423: 876-881
    • (2003) Nature , vol.423 , pp. 876-881
    • Sakai, T.1    Larsen, M.2    Yamada, K.M.3
  • 60
    • 33751545286 scopus 로고    scopus 로고
    • Igf2 deficiency results in delayed lung development at the end of gestation
    • Silva D, Venihaki M, Guo WH, Lopez MF (2006) Igf2 deficiency results in delayed lung development at the end of gestation. Endocrinology 147: 5584-5591
    • (2006) Endocrinology , vol.147 , pp. 5584-5591
    • Silva, D.1    Venihaki, M.2    Guo, W.H.3    Lopez, M.F.4
  • 61
    • 0025648762 scopus 로고
    • Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
    • Srivastava S, Zou ZQ, Pirollo K, Blattner W, Chang EH (1990) Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 348: 747-749
    • (1990) Nature , vol.348 , pp. 747-749
    • Srivastava, S.1    Zou, Z.Q.2    Pirollo, K.3    Blattner, W.4    Chang, E.H.5
  • 66
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 67
    • 77953973648 scopus 로고    scopus 로고
    • Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy
    • Ulanet DB, Ludwig DL, Kahn CR, Hanahan D (2010) Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy. Proc Natl Acad Sci USA 107: 10791-10798
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10791-10798
    • Ulanet, D.B.1    Ludwig, D.L.2    Kahn, C.R.3    Hanahan, D.4
  • 68
    • 78049423721 scopus 로고    scopus 로고
    • Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs
    • Ungewitter E, Scrable H (2010) Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs. Genes Dev 24: 2408-2419
    • (2010) Genes Dev , vol.24 , pp. 2408-2419
    • Ungewitter, E.1    Scrable, H.2
  • 71
    • 79957474904 scopus 로고    scopus 로고
    • Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study
    • Villani A, Tabori U, Schiffman J, Shlien A, Beyene J, Druker H, Novokmet A, Finlay J, Malkin D (2011) Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study. Lancet Oncol 12: 559-567
    • (2011) Lancet Oncol , vol.12 , pp. 559-567
    • Villani, A.1    Tabori, U.2    Schiffman, J.3    Shlien, A.4    Beyene, J.5    Druker, H.6    Novokmet, A.7    Finlay, J.8    Malkin, D.9
  • 72
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: the growing complexity of p53
    • Vousden KH, Prives C (2009) Blinded by the light: the growing complexity of p53. Cell 137: 413-431
    • (2009) Cell , vol.137 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 73
    • 0029757120 scopus 로고    scopus 로고
    • Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene
    • Werner H, Karnieli E, Rauscher FJ, LeRoith D (1996) Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene. Proc Natl Acad Sci USA 93: 8318-8323
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8318-8323
    • Werner, H.1    Karnieli, E.2    Rauscher, F.J.3    LeRoith, D.4
  • 74
    • 33748060942 scopus 로고    scopus 로고
    • Joint effects of germ-line p53 mutation and sex on cancer risk in Li-Fraumeni syndrome
    • Wu CC, Shete S, Amos CI, Strong LC (2006) Joint effects of germ-line p53 mutation and sex on cancer risk in Li-Fraumeni syndrome. Cancer Res 66: 8287-8292
    • (2006) Cancer Res , vol.66 , pp. 8287-8292
    • Wu, C.C.1    Shete, S.2    Amos, C.I.3    Strong, L.C.4
  • 77
    • 33745537075 scopus 로고    scopus 로고
    • Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues
    • Zaccheo OJ, Prince SN, Miller DM, Williams C, Kemp CF, Brown J, Jones EY, Catto LE, Crump MP, Hassan AB (2006) Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues. J Mol Biol 359: 403-421
    • (2006) J Mol Biol , vol.359 , pp. 403-421
    • Zaccheo, O.J.1    Prince, S.N.2    Miller, D.M.3    Williams, C.4    Kemp, C.F.5    Brown, J.6    Jones, E.Y.7    Catto, L.E.8    Crump, M.P.9    Hassan, A.B.10
  • 78
    • 67849114236 scopus 로고    scopus 로고
    • Pscan: finding over-represented transcription factor binding site motifs in sequences from co-regulated or co-expressed genes
    • Zambelli F, Pesole G, Pavesi G (2009) Pscan: finding over-represented transcription factor binding site motifs in sequences from co-regulated or co-expressed genes. Nucleic Acids Res 37: W247-252
    • (2009) Nucleic Acids Res , vol.37
    • Zambelli, F.1    Pesole, G.2    Pavesi, G.3
  • 79
    • 0029881592 scopus 로고    scopus 로고
    • Regulation of insulin-like growth factor II P3 promotor by p53: a potential mechanism for tumorigenesis
    • Zhang L, Kashanchi F, Zhan Q, Zhan S, Brady JN, Fornace AJ, Seth P, Helman LJ (1996) Regulation of insulin-like growth factor II P3 promotor by p53: a potential mechanism for tumorigenesis. Cancer Res 56: 1367-1373
    • (1996) Cancer Res , vol.56 , pp. 1367-1373
    • Zhang, L.1    Kashanchi, F.2    Zhan, Q.3    Zhan, S.4    Brady, J.N.5    Fornace, A.J.6    Seth, P.7    Helman, L.J.8
  • 80
    • 0031939952 scopus 로고    scopus 로고
    • p53 regulates human insulin-like growth factor II gene expression through active P4 promoter in rhabdomyosarcoma cells
    • Zhang L, Zhan Q, Zhan S, Kashanchi F, Fornace A, J Jr., Seth P, Helman LJ (1998) p53 regulates human insulin-like growth factor II gene expression through active P4 promoter in rhabdomyosarcoma cells. DNA Cell Biol 17: 125-131
    • (1998) DNA Cell Biol , vol.17 , pp. 125-131
    • Zhang, L.1    Zhan, Q.2    Zhan, S.3    Kashanchi, F.4    Fornace Jr, A.5    Seth, P.6    Helman, L.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.