Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice

Cancer Research

Volumn 60, Issue 4, 2000, Pages 1070-1076

  Hassan, A Bassim ^a   Howell, Julie A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C;

ALLELE; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; COLON ADENOMA; COLORECTAL CANCER; CONTROLLED STUDY; FAMILIAL COLON POLYPOSIS; FEMALE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH;

ADENOMA; ADENOMATOUS POLYPOSIS COLI; ANIMALS; CELL DIVISION; FEMALE; GENES, APC; INSULIN-LIKE GROWTH FACTOR II; INTESTINAL NEOPLASMS; MALE; MICE; MICE, INBRED C57BL;

EID: 0034652480     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Shoemaker, A. R., Gould, K. A., Luongo, C., Moser, A. R., and Dove, W. F. Studies of neoplasia in the Min mouse. Biochim. Biophys. Acta. 1332: F25-48, 1997.
2. Dietrich, W. F., Lander, E. S., Smith, J. S., Moser, A. R., Gould, K. A., Luongo, C., Borenstein, N., and Dove, W. Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell, 75: 631-639, 1993.
3. Cormier, R. T., Hong, K. H., Halberg, R. B., Hawkins, T. L., Richardson, P., Mulherkar, R., Dove, W. F., and Lander, E. S. Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis (see comments). Nat. Genet, 17: 88-91, 1997.
4. Tomlinson, I. P., Beck, N. E., Neale, K., and Bodmer, W. F. Variants at the secretory phospholipase A2 (PLA2G2A) locus: analysis of associations with familial adenomatous polyposis and sporadic colorectal tumours. Ann. Hum. Genet, 60: 369-376, 1996.
5. Nielsen, F. C. The molecular and cellular biology of insulin-like growth factor II. Prog. Growth Factor Res., 4: 257-290, 1992.
6. DeChiara, T. M., Efstratiadis, A., and Robertson, E. J. A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature (Lond.), 345: 78-80, 1990.
7. Eggenschwiler, J., Ludwig, T., Fisher, P., Leighton, P. A., Tilghman, S. M., and Efstratiadis, A. Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes. Genes Dev., 11: 3128-3142, 1997.
8. Lau, M. M., Stewart, C. E., Liu, Z., Bhatt, H., Rotwein, P., and Stewart, C. L. Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality. Genes Dev., 8: 2953-2963, 1994.
9. Ward, A., Bates, P., Fisher, R., Richardson, L., and Graham, C. F. Disproportionate growth in mice with Igf-2 transgenes. Proc. Natl. Acad. Sci. USA, 91: 10365-10369, 1994.
10. Joyce, J. A., Lam, W. K., Catchpoole, D. J., Jenks, P., Reik, W., Maher, E. R., and Schofield, P. N. Imprinting of IGF2 and H19: lack of reciprocity in sporadic Beckwith-Wiedemann syndrome. Hum. Mol. Genet., 6: 1543-1548, 1997.
11. Bates, P., Fisher, R., Ward, A., Richardson, L., Hill, D. J., and Graham, C. F. Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II) (see comments). Br. J. Cancer, 72: 1189-1193, 1995.
12. Rogler, C. E., Yang, D., Rossetti, L., Donohoe, J., Alt, E., Chang, C. J., Rosenfeld, R., Neely, K., and Hintz, R. Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice. J. Biol. Chem., 269: 13779-13784, 1994.
13. Biddle, C., Li, C. H., Schofield, P. N., Tate, V. E., Hopkins, B., Engstrom, W., Huskisson, N. S., and Graham, C. F. Insulin-like growth factors and the multiplication of Tera-2, a human teratoma-derived cell line. J. Cell. Sci., 90: 475-484, 1988.
14. Harrington, E, A., Bennett, M. R., Fanidi, A., and Evan, G. 1. c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J., 13: 3286-3295, 1994.
15. Downward, J. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell. Biol., 10: 262-267, 1998.
16. Zhang, L., Zhou, W., Velculescu, V. E., Kern, S. E., Hruban, R. H., Hamilton, S. R., Vogelstein, B., and Kinzler, K. W. Gene expression profiles in normal and cancer cells. Science (Washington DC), 276: 1268-1272, 1997.
17. Toretsky, J. A., and Helman, L. J. Involvement of IGF-II in human cancer. J. Endocrinol., 149: 367-372, 1996.
18. Cui, H., Horon, I. L., Ohlsson, R., Hamilton, S. R., and Feinberg, A. P. Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability (see comments). Nat. Med., 4: 1276-1280, 1998.
19. Boland, C. R., Thibodeau, S. N., Hamilton, S. R., Sidransky, D., Eshleman, J. R., Burt, R. W., Meltzer, S. J., Rodriguez Bigas, M. A., Fodde, R., Ranzani, G. N., and Srivastava, S. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellile instability in colorectal cancer. Cancer Res., 58: 5248-5257, 1998.
20. Da Costa, T. H., Williamson, D. H., Ward, A., Bates, P., Fisher, R., Richardson. L., Hill, D. J., Robinson, I. C., and Graham, C. F. High plasma insulin-like growth factor-II and low lipid content in transgenic mice: measurements of lipid metabolism. J. Endocrinol., 143: 433-439, 1994.
21. Wasan, H. S., Novelli, M., Bee, J., and Bodmer, W. F. Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice. Proc. Natl. Acad. Sci. USA, 94: 3308-3313, 1997.
22. Dove, W. F., Clipson, L., Gould, K. A., Luongo, C., Marshall, D. J., Moser, A. R., Newton, M. A., and Jacoby, R. F. Intestinal neoplasia in the ApcMin mouse: independence from the microbial and natural killer (beige locus) status. Cancer Res., 57: 812-814, 1997.
23. UKCCCR. United Kingdom Coordinating Committee on Cancer Research (UKCCCR) Guidelines for the welfare of animals in experimental neoplasia (2nd ed.). Br. J. Cancer, 77: 1-10, 1998.
24. Kearsey, S. E., and Labib, K. MCM proteins: evolution, properties, and role in DNA replication. Biochim. Biophys. Acta, 1398: 113-136, 1998.
25. Todorov, I. T., Werness, B. A., Wang, H. Q., Buddharaju, L. N., Todorova, P. D., Slocum, H. K., Brooks, J. S., and Huberman, J. A. HsMCM2/BM28: a novel proliferation marker for human tumors and normal tissues. Lab. Invest., 78: 73-78, 1998.
26. Kiyama, H., and Emson, P. C. An in situ hybridization histochemistry method for the use of alkaline phosphatase-labeled oligonucleotide probes in small intestine. J. Histochem. Cytochem., 39: 1377-1384, 1991.
27. Gould, K. A., Luongo, C., Moser, A. R., McNeley, M. K., Borenstein, N., Shedlovsky, A., Dove, W. F., Hong, K., Dietrich, W. F., and Lander, E. S. Genetic evaluation of candidate genes for the Mom1 modifier of intestinal neoplasia in mice. Genetics, 144: 1777-1785, 1996.
28. Bailleul, B., Surani, M. A., White, S., Barton, S. C., Brown, K., Blessing, M., Jorcano, J., and Balmain, A. Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter. Cell, 62: 697-708, 1990.
29. Wang, J., Niu, W., Nikiforov, Y., Naito, S., Chernausek, S., Witte, D., LeRoith, D., Strauch, A., and Fagin, J. A. Targeted overexpression of IGF-1 evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice. J. Clin. Invest., 100: 1425-1439, 1997.
30. Zaina, S., and Squire, S. The soluble type 2 insulin-like growth factor (IGF-II) receptor reduces organ size by IGF-II-mediated and IGF-II-independent mechanisms. J. Biol. Chem., 273: 28610-28616, 1998.
31. MacDonald, R. S. The role of insulin-like growth factors in small intestinal cell growth and development. Horm. Metab. Res., 31: 103-113, 1999.
32. DeChiara, T. M., Robertson, E. J., and Efstratiadis, A. Parental imprinting of the mouse insulin-like growth factor II gene. Cell, 64: 849-859, 1991.
33. Zhu, Y., Richardson, J. A., Parada, L. F., and Graff, J. M. Smad3 mutant mice develop metastatic colorectal cancer. Cell, 94: 703-714, 1998.
34. Rashid, Z., and Basson, M. D. Association of rectal prolapse with colorectal cancer. Surgery, 119: 51-55, 1996.
35. Christofori, G., Naik, P., and Hanahan, D. A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis. Nature (Lond.), 369: 414-418, 1994.
36. Christofori, G., Naik, P., and Hanahan, D. Deregulation of both imprinted and expressed alleles of the insulin-like growth factor 2 gene during beta-cell tumorigenesis. Nat. Genet., 10: 196-201, 1995.
37. Harris, T. M., Rogler, L. E., and Rogler, C. E. Reactivation of the maternally imprinted IGF2 allele in TGFα induced hepatocellular carcinomas in mice. Oncogene, 16: 203-209, 1997.
38. Haddad, R., and Held, W. A. Genomic imprinting and Igf2 influence liver tumorigenesis and loss of heterozygosity in SV40 T antigen transgenic mice. Cancer Res., 57: 4615-4623, 1997.
39. Wasan, H. S., Park, H. S., Liu, K. C., Mandir, N. K., Winnett, A., Sasieni, P., Bodmer, W. F., Goodlad, R. A., and Wright, N. A. APC in the regulation of intestinal crypt fission. J. Pathol., 185: 246-255, 1998.
40. He, T. C., Sparks, A. B., Rago, C., Hermeking, H., Zawel, L., da Costa, L. T., Morin, P. J., Vogelstein, B., and Kinzler, K. W. Identification of c-MYC as a target of the APC pathway (see comments). Science (Washington DC), 281: 1509-1512, 1998.
41. Zindy, F., Eischen, C. M., Randle, D. H., Kamijo, T., Cleveland, J. L., Sherr, C. J., and Roussel, M. F. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev., 12: 2424-2433, 1998.
42. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell, 91: 231-241, 1997.
43. Ron, E., Gridley, G., Hrubec, Z., Page, W., Arora, S., and Fraumeni, J. F., Jr. Acromegaly and gastrointestinal cancer. Cancer (Phila.), 68: 1673-1677, 1991.
44. Gurdon, J. B. A community effect in animal development. Nature (Lond.), 336: 772-774, 1988.
45. Markowitz, S., Wang, J., Myeroff, L., Parsons, R., Sun, L., Lutterbaugh, J., Fan, R. S., Zborowska, E., Kinzler, K. W., Vogelstein, B., Brattain, M., and Willson, J. K. V. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability (see comments). Science (Washington DC). 268: 1336-1338, 1995.
46. Souza, R. F., Appel, R., Yin, J., Wang, S., Smolinski, K. N., Abraham, J. M., Zou, T. T., Shi, Y. Q., Lei, J., Cottrell, J., Cymes, K., Biden, K., Simms, L., Leggett, B., Lynch, P. M., Frazier, M., Powell, S. M., Harpaz, N., Sugimura, H., Young, J., and Meltzer, S. J. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nat. Genet., 14: 255-257, 1996.
47. Takaku, K., Oshima, M., Miyoshi, H., Matsui, M., Seldin, M. F., and Taketo, M. M. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell, 92: 645-656, 1998.
48. Tomlinson, I. P., and Bodmer, W. F. Failure of programmed cell death and differentiation as causes of tumors: some simple mathematical models. Proc. Natl. Acad. Sci. USA., 92: 11130-11134, 1995.
49. Giannoukakis, N., Deal, C., Paquette, J., Goodyer, C. G., and Polychronakos, C. Parental genomic imprinting of the human IGF2 gene. Nat. Genet., 4: 98-101, 1993.