Functional characterization of novel presenilin-2 variants identified in human breast cancers

Oncogene

Volumn 25, Issue 25, 2006, Pages 3557-3564

  To, M D ^a,b,g   Gokgoz, N ^a   Doyle, T G ^c   Donoviel, D B ^a,h   Knight, J A ^a,d   Hyslop, P S ^b,e   Bernstein, A ^a,b,f   Andrulis, I L ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f CANADIAN INSTITUTES OF HEALTH RESEARCH   (Canada)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h LEXICON PHARMACEUTICALS INC   (United States)

Author keywords

Alzheimer's disease; Breast cancer; Presenilins; PS 2; Susceptibility

Indexed keywords

PRESENILIN 2;

ADULT; ALLELE; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BREAST CANCER; CAENORHABDITIS ELEGANS; CANCER RISK; CANCER SUSCEPTIBILITY; CELL GROWTH; CELL GROWTH INHIBITION; CONTROLLED STUDY; EMBRYO; FEMALE; FIBROBLAST; GENE DOSAGE; GENE FREQUENCY; GENE MUTATION; GENETIC SUSCEPTIBILITY; GERM LINE; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; STATISTICAL SIGNIFICANCE;

ALLELES; ANIMALS; BREAST NEOPLASMS; CELL PROLIFERATION; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; MICE; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PRESENILIN-2;

CAENORHABDITIS ELEGANS;

EID: 33745168977     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209397     Document Type: Article

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