메뉴 건너뛰기




Volumn 162, Issue 1, 2012, Pages 45-55

Nanotechnology applied to overcome tumor drug resistance

Author keywords

Chemotherapy; Drug delivery system; Emerging multidrug resistance; Nanotechnology; Tumor

Indexed keywords

ANTICANCER DRUG; DRUG DELIVERY SYSTEM; DRUG RESISTANCE; MALIGNANT DISEASE; MULTIDRUG RESISTANCE; NANOCARRIERS; OPTIMAL DOSAGE; SMALL MOLECULES; TRANSPORT KINETIC; TUMOR CELLS; TUMOR MICROENVIRONMENT; TUMOR-STROMA;

EID: 84864696659     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.05.051     Document Type: Review
Times cited : (277)

References (134)
  • 1
    • 0033800091 scopus 로고    scopus 로고
    • Multicellular resistance: A paradigm for clinical resistance?
    • B. Desoize, and J. Jardillier Multicellular resistance: a paradigm for clinical resistance? Crit. Rev. Oncol. Hematol. 36 2000 193 207
    • (2000) Crit. Rev. Oncol. Hematol. , vol.36 , pp. 193-207
    • Desoize, B.1    Jardillier, J.2
  • 2
    • 23844481408 scopus 로고    scopus 로고
    • Mechanisms of drug resistance in cancer chemotherapy
    • Y.A. Luqmani Mechanisms of drug resistance in cancer chemotherapy Med. Princ. Pract. 14 Suppl. 1 2005 35 48
    • (2005) Med. Princ. Pract. , vol.14 , Issue.SUPPL. 1 , pp. 35-48
    • Luqmani, Y.A.1
  • 3
    • 0026735778 scopus 로고
    • Mechanisms of multidrug resistance in cancer treatment
    • A.L. Harris, and D. Hochhauser Mechanisms of multidrug resistance in cancer treatment Acta Oncol. 31 1992 205 213
    • (1992) Acta Oncol. , vol.31 , pp. 205-213
    • Harris, A.L.1    Hochhauser, D.2
  • 5
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • M.M. Gottesman Mechanisms of cancer drug resistance Annu. Rev. Med. 53 2002 615 627
    • (2002) Annu. Rev. Med. , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 6
    • 73949102380 scopus 로고    scopus 로고
    • Multidrug resistance in cancer
    • B.C. Baguley Multidrug resistance in cancer Methods Mol. Biol. 596 2010 1 14
    • (2010) Methods Mol. Biol. , vol.596 , pp. 1-14
    • Baguley, B.C.1
  • 7
    • 4344571205 scopus 로고    scopus 로고
    • Enhancement of the efficacy of chemotherapy for lung cancer by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense: Novel multicomponent delivery system
    • R.I. Pakunlu, Y. Wang, W. Tsao, V. Pozharov, T.J. Cook, and T. Minko Enhancement of the efficacy of chemotherapy for lung cancer by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense: novel multicomponent delivery system Cancer Res. 64 2004 6214 6224
    • (2004) Cancer Res. , vol.64 , pp. 6214-6224
    • Pakunlu, R.I.1    Wang, Y.2    Tsao, W.3    Pozharov, V.4    Cook, T.J.5    Minko, T.6
  • 8
    • 57149142257 scopus 로고    scopus 로고
    • Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer
    • M. Saad, O.B. Garbuzenko, and T. Minko Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer Nanomedicine (Lond.) 3 2008 761 776
    • (2008) Nanomedicine (Lond.) , vol.3 , pp. 761-776
    • Saad, M.1    Garbuzenko, O.B.2    Minko, T.3
  • 9
    • 79960704268 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of lonidamine/paclitaxel loaded. EGFR-targeted nanoparticles in an orthotopic animal model of multi-drug resistant breast cancer
    • L. Milane, Z.F. Duan, and M. Amiji Pharmacokinetics and biodistribution of lonidamine/paclitaxel loaded. EGFR-targeted nanoparticles in an orthotopic animal model of multi-drug resistant breast cancer Nanomedicine 7 2011 435 444
    • (2011) Nanomedicine , vol.7 , pp. 435-444
    • Milane, L.1    Duan, Z.F.2    Amiji, M.3
  • 10
    • 67349243616 scopus 로고    scopus 로고
    • Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance
    • Y. Patil, T. Sadhukha, L. Ma, and J. Panyam Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance J. Control. Release 136 2009 21 29
    • (2009) J. Control. Release , vol.136 , pp. 21-29
    • Patil, Y.1    Sadhukha, T.2    Ma, L.3    Panyam, J.4
  • 11
    • 75549088350 scopus 로고    scopus 로고
    • The therapeutic response to multifunctional polymeric nano-conjugates in the targeted cellular and subcellular delivery of doxorubicin
    • X.B. Xiong, Z. Ma, R. Lai, and A. Lavasanifar The therapeutic response to multifunctional polymeric nano-conjugates in the targeted cellular and subcellular delivery of doxorubicin Biomaterials 31 2010 757 768
    • (2010) Biomaterials , vol.31 , pp. 757-768
    • Xiong, X.B.1    Ma, Z.2    Lai, R.3    Lavasanifar, A.4
  • 12
    • 77951950804 scopus 로고    scopus 로고
    • Imaging and inhibition of multi-drug resistance in cancer cells via specific association with negatively charged CdTe quantum dots
    • Y. Zhou, L. Shi, Q. Li, H. Jiang, G. Lv, J. Zhao, C. Wu, M. Selke, and X. Wang Imaging and inhibition of multi-drug resistance in cancer cells via specific association with negatively charged CdTe quantum dots Biomaterials 31 2010 4958 4963
    • (2010) Biomaterials , vol.31 , pp. 4958-4963
    • Zhou, Y.1    Shi, L.2    Li, Q.3    Jiang, H.4    Lv, G.5    Zhao, J.6    Wu, C.7    Selke, M.8    Wang, X.9
  • 13
    • 84860393608 scopus 로고    scopus 로고
    • Gold-doxorubicin nanoconjugates for overcoming multidrug resistance
    • Y.J. Gu, J. Cheng, C.W. Man, W.T. Wong, and S.H. Cheng Gold-doxorubicin nanoconjugates for overcoming multidrug resistance Nanomedicine 8 2012 204 211
    • (2012) Nanomedicine , vol.8 , pp. 204-211
    • Gu, Y.J.1    Cheng, J.2    Man, C.W.3    Wong, W.T.4    Cheng, S.H.5
  • 15
    • 78650677484 scopus 로고    scopus 로고
    • Polymer conjugates of the highly potent cytostatic drug 2-pyrrolinodoxorubicin
    • M. Studenovsky, K. Ulbrich, M. Ibrahimova, and B. Rihova Polymer conjugates of the highly potent cytostatic drug 2-pyrrolinodoxorubicin Eur. J. Pharm. Sci. 42 2011 156 163
    • (2011) Eur. J. Pharm. Sci. , vol.42 , pp. 156-163
    • Studenovsky, M.1    Ulbrich, K.2    Ibrahimova, M.3    Rihova, B.4
  • 16
    • 38749150591 scopus 로고    scopus 로고
    • Preparation and cytotoxic activity of poly(ethylene glycol)-modified poly(amidoamine) dendrimers bearing adriamycin
    • K. Kono, C. Kojima, N. Hayashi, E. Nishisaka, K. Kiura, S. Watarai, and A. Harada Preparation and cytotoxic activity of poly(ethylene glycol)-modified poly(amidoamine) dendrimers bearing adriamycin Biomaterials 29 2008 1664 1675
    • (2008) Biomaterials , vol.29 , pp. 1664-1675
    • Kono, K.1    Kojima, C.2    Hayashi, N.3    Nishisaka, E.4    Kiura, K.5    Watarai, S.6    Harada, A.7
  • 17
    • 82755161993 scopus 로고    scopus 로고
    • Minicells: Versatile vectors for targeted drug or si/shRNA cancer therapy
    • J.A. MacDiarmid, and H. Brahmbhatt Minicells: versatile vectors for targeted drug or si/shRNA cancer therapy Curr. Opin. Biotechnol. 22 2011 909 916
    • (2011) Curr. Opin. Biotechnol. , vol.22 , pp. 909-916
    • MacDiarmid, J.A.1    Brahmbhatt, H.2
  • 18
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Y. Matsumura, and H. Maeda A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs Cancer Res. 46 1986 6387 6392
    • (1986) Cancer Res. , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 20
    • 80054900051 scopus 로고    scopus 로고
    • The potential of drug-carrying immunoliposomes as anticancer agents
    • (Commentary re:) J.W. Park, Clin. Cancer Res. Clin. Cancer Res. 8 2002 955 956
    • D.R. Siwak, A.M. Tari, and G. Lopez-Berestein The potential of drug-carrying immunoliposomes as anticancer agents (Commentary re:) J.W. Park, Anti-HER2 immunoliposomes: enhanced efficacy due to targeted delivery Clin. Cancer Res. 8 2002 1172 1181 Clin. Cancer Res. 8 2002 955 956
    • (2002) Anti-HER2 Immunoliposomes: Enhanced Efficacy Due to Targeted Delivery , vol.8 , pp. 1172-1181
    • Siwak, D.R.1    Tari, A.M.2    Lopez-Berestein, G.3
  • 23
    • 69249212582 scopus 로고    scopus 로고
    • Tumor-targeting amino acid auxotrophic Salmonella typhimurium
    • R.M. Hoffman Tumor-targeting amino acid auxotrophic Salmonella typhimurium Amino Acids 37 2009 509 521
    • (2009) Amino Acids , vol.37 , pp. 509-521
    • Hoffman, R.M.1
  • 25
    • 11044222650 scopus 로고    scopus 로고
    • Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
    • A.K. Gupta, and M. Gupta Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications Biomaterials 26 2005 3995 4021
    • (2005) Biomaterials , vol.26 , pp. 3995-4021
    • Gupta, A.K.1    Gupta, M.2
  • 26
    • 14844303778 scopus 로고    scopus 로고
    • Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor
    • E.S. Lee, K. Na, and Y.H. Bae Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor J Control. Release 103 2005 405 418
    • (2005) J Control. Release , vol.103 , pp. 405-418
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 27
    • 84858616110 scopus 로고    scopus 로고
    • A Lipo-PEG-PEI complex for encapsulating curcumin that enhances its antitumor effects on curcumin-sensitive and curcumin-resistance cells
    • Y.L. Lin, Y.K. Liu, N.M. Tsai, J.H. Hsieh, C.H. Chen, C.M. Lin, and K.W. Liao A Lipo-PEG-PEI complex for encapsulating curcumin that enhances its antitumor effects on curcumin-sensitive and curcumin-resistance cells Nanomedicine 8 2012 318 327
    • (2012) Nanomedicine , vol.8 , pp. 318-327
    • Lin, Y.L.1    Liu, Y.K.2    Tsai, N.M.3    Hsieh, J.H.4    Chen, C.H.5    Lin, C.M.6    Liao, K.W.7
  • 28
    • 79953048071 scopus 로고    scopus 로고
    • Tumor delivery of macromolecular drugs based on the EPR effect
    • V. Torchilin Tumor delivery of macromolecular drugs based on the EPR effect Adv. Drug Deliv. Rev. 63 2011 131 135
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 131-135
    • Torchilin, V.1
  • 29
    • 0027299899 scopus 로고
    • Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure
    • C.J. Li, Y. Miyamoto, Y. Kojima, and H. Maeda Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure Br. J. Cancer 67 1993 975 980
    • (1993) Br. J. Cancer , vol.67 , pp. 975-980
    • Li, C.J.1    Miyamoto, Y.2    Kojima, Y.3    Maeda, H.4
  • 30
    • 85010645761 scopus 로고    scopus 로고
    • SMANCS dynamic therapy for various advanced solid tumors and promising clinical effects: Enhanced drug delivery by hydrodynamic modulation with vascular mediators, particularly angiotensin II, during arterial infusion
    • A. Nagamitsu, T. Inuzuka, K. Greish, and H. Maeda SMANCS dynamic therapy for various advanced solid tumors and promising clinical effects: enhanced drug delivery by hydrodynamic modulation with vascular mediators, particularly angiotensin II, during arterial infusion Drug Deliv. Syst. 22-5 2007 510 521
    • (2007) Drug Deliv. Syst. , vol.22-25 , pp. 510-521
    • Nagamitsu, A.1    Inuzuka, T.2    Greish, K.3    Maeda, H.4
  • 31
    • 0033567094 scopus 로고    scopus 로고
    • Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor
    • W.L. Monsky, D. Fukumura, T. Gohongi, M. Ancukiewcz, H.A. Weich, V.P. Torchilin, F. Yuan, and R.K. Jain Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor Cancer Res. 59 1999 4129 4135
    • (1999) Cancer Res. , vol.59 , pp. 4129-4135
    • Monsky, W.L.1    Fukumura, D.2    Gohongi, T.3    Ancukiewcz, M.4    Weich, H.A.5    Torchilin, V.P.6    Yuan, F.7    Jain, R.K.8
  • 33
    • 0842279809 scopus 로고
    • Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors
    • A. Gabizon, and D. Papahadjopoulos Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors Proc. Natl. Acad. Sci. U. S. A. 85 1988 6949 6953
    • (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , pp. 6949-6953
    • Gabizon, A.1    Papahadjopoulos, D.2
  • 34
    • 56749098212 scopus 로고    scopus 로고
    • Designing PEGylated therapeutic molecules: Advantages in ADMET properties
    • M. Hamidi, P. Rafiei, and A. Azadi Designing PEGylated therapeutic molecules: advantages in ADMET properties Expert Opin. Drug Discov. 3 2008 1293 1307
    • (2008) Expert Opin. Drug Discov. , vol.3 , pp. 1293-1307
    • Hamidi, M.1    Rafiei, P.2    Azadi, A.3
  • 35
    • 28844488494 scopus 로고    scopus 로고
    • Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
    • D.E. Owens 3rd, and N.A. Peppas Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles Int. J. Pharm. 307 2006 93 102
    • (2006) Int. J. Pharm. , vol.307 , pp. 93-102
    • Owens III, D.E.1    Peppas, N.A.2
  • 36
    • 0036155132 scopus 로고    scopus 로고
    • Pegnology: A review of PEG-ylated systems
    • D. Bhadra, S. Bhadra, P. Jain, and N.K. Jain Pegnology: a review of PEG-ylated systems Pharmazie 57 2002 5 29
    • (2002) Pharmazie , vol.57 , pp. 5-29
    • Bhadra, D.1    Bhadra, S.2    Jain, P.3    Jain, N.K.4
  • 37
    • 12344307628 scopus 로고    scopus 로고
    • Drug transport to brain with targeted nanoparticles
    • J.C. Olivier Drug transport to brain with targeted nanoparticles NeuroRx 2 2005 108 119
    • (2005) NeuroRx , vol.2 , pp. 108-119
    • Olivier, J.C.1
  • 38
  • 39
    • 33750417183 scopus 로고    scopus 로고
    • Targeted delivery of antisense oligodeoxynucleotide and small interference RNA into lung cancer cells
    • S.D. Li, and L. Huang Targeted delivery of antisense oligodeoxynucleotide and small interference RNA into lung cancer cells Mol. Pharm. 3 2006 579 588
    • (2006) Mol. Pharm. , vol.3 , pp. 579-588
    • Li, S.D.1    Huang, L.2
  • 40
    • 77954309207 scopus 로고    scopus 로고
    • Efficient overcoming of drug resistance to anticancer nucleoside analogs by nanodelivery of active phosphorylated drugs
    • C.M. Galmarini, G. Warren, M.T. Senanayake, and S.V. Vinogradov Efficient overcoming of drug resistance to anticancer nucleoside analogs by nanodelivery of active phosphorylated drugs Int. J. Pharm. 395 2010 281 289
    • (2010) Int. J. Pharm. , vol.395 , pp. 281-289
    • Galmarini, C.M.1    Warren, G.2    Senanayake, M.T.3    Vinogradov, S.V.4
  • 41
    • 77957279700 scopus 로고    scopus 로고
    • Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin
    • J. Jiang, S.J. Yang, J.C. Wang, L.J. Yang, Z.Z. Xu, T. Yang, X.Y. Liu, and Q. Zhang Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin Eur. J. Pharm. Biopharm. 76 2010 170 178
    • (2010) Eur. J. Pharm. Biopharm. , vol.76 , pp. 170-178
    • Jiang, J.1    Yang, S.J.2    Wang, J.C.3    Yang, L.J.4    Xu, Z.Z.5    Yang, T.6    Liu, X.Y.7    Zhang, Q.8
  • 43
    • 77951086240 scopus 로고    scopus 로고
    • Effects of cleavable PEG-cholesterol derivatives on the accelerated blood clearance of PEGylated liposomes
    • H. Xu, K.Q. Wang, Y.H. Deng, and W. Chen da Effects of cleavable PEG-cholesterol derivatives on the accelerated blood clearance of PEGylated liposomes Biomaterials 31 2010 4757 4763
    • (2010) Biomaterials , vol.31 , pp. 4757-4763
    • Xu, H.1    Wang, K.Q.2    Deng, Y.H.3    Chen Da, W.4
  • 44
    • 47349097049 scopus 로고    scopus 로고
    • Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance
    • E.S. Lee, Z. Gao, D. Kim, K. Park, I.C. Kwon, and Y.H. Bae Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance J. Control. Release 129 2008 228 236
    • (2008) J. Control. Release , vol.129 , pp. 228-236
    • Lee, E.S.1    Gao, Z.2    Kim, D.3    Park, K.4    Kwon, I.C.5    Bae, Y.H.6
  • 45
    • 80053929634 scopus 로고    scopus 로고
    • Emerging nanomaterials for targeting subcellular organelles
    • J.G. Huang, T. Leshuk, and F.X. Gu Emerging nanomaterials for targeting subcellular organelles Nano Today 6 2011 478 492
    • (2011) Nano Today , vol.6 , pp. 478-492
    • Huang, J.G.1    Leshuk, T.2    Gu, F.X.3
  • 46
    • 51049090204 scopus 로고    scopus 로고
    • Nanoparticle therapeutics: An emerging treatment modality for cancer
    • M.E. Davis, Z.G. Chen, and D.M. Shin Nanoparticle therapeutics: an emerging treatment modality for cancer Nat. Rev. Drug Discov. 7 2008 771 782
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 771-782
    • Davis, M.E.1    Chen, Z.G.2    Shin, D.M.3
  • 48
    • 60749108001 scopus 로고    scopus 로고
    • Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
    • H. Maeda, G.Y. Bharate, and J. Daruwalla Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect Eur. J. Pharm. Biopharm. 71 2009 409 419
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , pp. 409-419
    • Maeda, H.1    Bharate, G.Y.2    Daruwalla, J.3
  • 49
    • 20444375424 scopus 로고    scopus 로고
    • Selective targeting of antibody-conjugated nanoparticles to leukemic cells and primary T-lymphocytes
    • N. Dinauer, S. Balthasar, C. Weber, J. Kreuter, K. Langer, and H. von Briesen Selective targeting of antibody-conjugated nanoparticles to leukemic cells and primary T-lymphocytes Biomaterials 26 2005 5898 5906
    • (2005) Biomaterials , vol.26 , pp. 5898-5906
    • Dinauer, N.1    Balthasar, S.2    Weber, C.3    Kreuter, J.4    Langer, K.5    Von Briesen, H.6
  • 50
    • 79953054576 scopus 로고    scopus 로고
    • The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
    • J. Fang, H. Nakamura, and H. Maeda The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect Adv. Drug Deliv. Rev. 63 2011 136 151
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 136-151
    • Fang, J.1    Nakamura, H.2    Maeda, H.3
  • 51
    • 55849099605 scopus 로고    scopus 로고
    • Active targeting schemes for nanoparticle systems in cancer therapeutics
    • J.D. Byrne, T. Betancourt, and L. Brannon-Peppas Active targeting schemes for nanoparticle systems in cancer therapeutics Adv. Drug Deliv. Rev. 60 2008 1615 1626
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 1615-1626
    • Byrne, J.D.1    Betancourt, T.2    Brannon-Peppas, L.3
  • 52
    • 1842450748 scopus 로고    scopus 로고
    • The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers
    • M.G. Qaddoumi, H. Ueda, J. Yang, J. Davda, V. Labhasetwar, and V.H. Lee The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers Pharm. Res. 21 2004 641 648
    • (2004) Pharm. Res. , vol.21 , pp. 641-648
    • Qaddoumi, M.G.1    Ueda, H.2    Yang, J.3    Davda, J.4    Labhasetwar, V.5    Lee, V.H.6
  • 53
    • 0042634190 scopus 로고    scopus 로고
    • Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(d, l-lactide-co-glycolide) nanoparticles
    • J. Panyam, S.K. Sahoo, S. Prabha, T. Bargar, and V. Labhasetwar Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(d, l-lactide-co-glycolide) nanoparticles Int. J. Pharm. 262 2003 1 11
    • (2003) Int. J. Pharm. , vol.262 , pp. 1-11
    • Panyam, J.1    Sahoo, S.K.2    Prabha, S.3    Bargar, T.4    Labhasetwar, V.5
  • 55
    • 33845616309 scopus 로고    scopus 로고
    • Preparation of hemoglobin-loaded nano-sized particles with porous structure as oxygen carriers
    • J. Zhao, C.S. Liu, Y. Yuan, X.Y. Tao, X.Q. Shan, Y. Sheng, and F. Wu Preparation of hemoglobin-loaded nano-sized particles with porous structure as oxygen carriers Biomaterials 28 2007 1414 1422
    • (2007) Biomaterials , vol.28 , pp. 1414-1422
    • Zhao, J.1    Liu, C.S.2    Yuan, Y.3    Tao, X.Y.4    Shan, X.Q.5    Sheng, Y.6    Wu, F.7
  • 56
    • 42049089314 scopus 로고    scopus 로고
    • Overcoming the formulation obstacles towards targeted chemotherapy: In vitro and in vivo evaluation of cytotoxic drug loaded immunonanoparticles
    • N. Debotton, M. Parnes, J. Kadouche, and S. Benita Overcoming the formulation obstacles towards targeted chemotherapy: in vitro and in vivo evaluation of cytotoxic drug loaded immunonanoparticles J. Control. Release 127 2008 219 230
    • (2008) J. Control. Release , vol.127 , pp. 219-230
    • Debotton, N.1    Parnes, M.2    Kadouche, J.3    Benita, S.4
  • 57
    • 51249122212 scopus 로고    scopus 로고
    • Does a targeting ligand influence nanoparticle tumor localization or uptake?
    • K.F. Pirollo, and E.H. Chang Does a targeting ligand influence nanoparticle tumor localization or uptake? Trends Biotechnol. 26 2008 552 558
    • (2008) Trends Biotechnol. , vol.26 , pp. 552-558
    • Pirollo, K.F.1    Chang, E.H.2
  • 58
    • 33747840618 scopus 로고    scopus 로고
    • Polymer conjugates as anticancer nanomedicines
    • R. Duncan Polymer conjugates as anticancer nanomedicines Nat. Rev. Cancer 6 2006 688 701
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 688-701
    • Duncan, R.1
  • 59
    • 0028304405 scopus 로고
    • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft
    • F. Yuan, M. Leunig, S.K. Huang, D.A. Berk, D. Papahadjopoulos, and R.K. Jain Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft Cancer Res. 54 1994 3352 3356
    • (1994) Cancer Res. , vol.54 , pp. 3352-3356
    • Yuan, F.1    Leunig, M.2    Huang, S.K.3    Berk, D.A.4    Papahadjopoulos, D.5    Jain, R.K.6
  • 60
    • 70649115439 scopus 로고    scopus 로고
    • The characteristics and performance of a multifunctional nanoassembly system for the co-delivery of docetaxel and iSur-pDNA in a mouse hepatocellular carcinoma model
    • Z. Xu, Z. Zhang, Y. Chen, L. Chen, L. Lin, and Y. Li The characteristics and performance of a multifunctional nanoassembly system for the co-delivery of docetaxel and iSur-pDNA in a mouse hepatocellular carcinoma model Biomaterials 31 2010 916 922
    • (2010) Biomaterials , vol.31 , pp. 916-922
    • Xu, Z.1    Zhang, Z.2    Chen, Y.3    Chen, L.4    Lin, L.5    Li, Y.6
  • 62
    • 70350707597 scopus 로고    scopus 로고
    • The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance
    • Y.B. Patil, S.K. Swaminathan, T. Sadhukha, L. Ma, and J. Panyam The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance Biomaterials 31 2010 358 365
    • (2010) Biomaterials , vol.31 , pp. 358-365
    • Patil, Y.B.1    Swaminathan, S.K.2    Sadhukha, T.3    Ma, L.4    Panyam, J.5
  • 63
    • 77949656381 scopus 로고    scopus 로고
    • Reversion of multidrug resistance by tumor targeted delivery of antisense oligodeoxynucleotides in hydroxypropyl-chitosan nanoparticles
    • J. Wang, X. Tao, Y. Zhang, D. Wei, and Y. Ren Reversion of multidrug resistance by tumor targeted delivery of antisense oligodeoxynucleotides in hydroxypropyl-chitosan nanoparticles Biomaterials 31 2010 4426 4433
    • (2010) Biomaterials , vol.31 , pp. 4426-4433
    • Wang, J.1    Tao, X.2    Zhang, Y.3    Wei, D.4    Ren, Y.5
  • 64
    • 34848911993 scopus 로고    scopus 로고
    • Reversal of multidrug resistance by transferrin-conjugated liposomes co-encapsulating doxorubicin and verapamil
    • J. Wu, Y. Lu, A. Lee, X. Pan, X. Yang, X. Zhao, and R.J. Lee Reversal of multidrug resistance by transferrin-conjugated liposomes co-encapsulating doxorubicin and verapamil J. Pharm. Pharm. Sci. 10 2007 350 357
    • (2007) J. Pharm. Pharm. Sci. , vol.10 , pp. 350-357
    • Wu, J.1    Lu, Y.2    Lee, A.3    Pan, X.4    Yang, X.5    Zhao, X.6    Lee, R.J.7
  • 65
    • 77950160186 scopus 로고    scopus 로고
    • P-glycoprotein antibody functionalized carbon nanotube overcomes the multidrug resistance of human leukemia cells
    • R. Li, R. Wu, L. Zhao, M. Wu, L. Yang, and H. Zou P-glycoprotein antibody functionalized carbon nanotube overcomes the multidrug resistance of human leukemia cells ACS Nano 4 2010 1399 1408
    • (2010) ACS Nano , vol.4 , pp. 1399-1408
    • Li, R.1    Wu, R.2    Zhao, L.3    Wu, M.4    Yang, L.5    Zou, H.6
  • 67
    • 58849095012 scopus 로고    scopus 로고
    • Evaluations of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells
    • S. Yadav, L.E. van Vlerken, S.R. Little, and M.M. Amiji Evaluations of combination MDR-1 gene silencing and paclitaxel administration in biodegradable polymeric nanoparticle formulations to overcome multidrug resistance in cancer cells Cancer Chemother. Pharmacol. 63 2009 711 722
    • (2009) Cancer Chemother. Pharmacol. , vol.63 , pp. 711-722
    • Yadav, S.1    Van Vlerken, L.E.2    Little, S.R.3    Amiji, M.M.4
  • 71
    • 59649088061 scopus 로고    scopus 로고
    • The role of hydrophobic amino acid grafts in the enhancement of membrane-disruptive activity of pH-responsive pseudo-peptides
    • R. Chen, S. Khormaee, M.E. Eccleston, and N.K. Slater The role of hydrophobic amino acid grafts in the enhancement of membrane-disruptive activity of pH-responsive pseudo-peptides Biomaterials 30 2009 1954 1961
    • (2009) Biomaterials , vol.30 , pp. 1954-1961
    • Chen, R.1    Khormaee, S.2    Eccleston, M.E.3    Slater, N.K.4
  • 72
    • 0034104453 scopus 로고    scopus 로고
    • Resistance mechanisms associated with altered intracellular distribution of anticancer agents
    • A.K. Larsen, A.E. Escargueil, and A. Skladanowski Resistance mechanisms associated with altered intracellular distribution of anticancer agents Pharmacol. Ther. 85 2000 217 229
    • (2000) Pharmacol. Ther. , vol.85 , pp. 217-229
    • Larsen, A.K.1    Escargueil, A.E.2    Skladanowski, A.3
  • 73
    • 67349140207 scopus 로고    scopus 로고
    • Degradable poly(beta-amino ester) nanoparticles for cancer cytoplasmic drug delivery
    • Y. Shen, H. Tang, Y. Zhan, E.A. Van Kirk, and W.J. Murdoch Degradable poly(beta-amino ester) nanoparticles for cancer cytoplasmic drug delivery Nanomedicine 5 2009 192 201
    • (2009) Nanomedicine , vol.5 , pp. 192-201
    • Shen, Y.1    Tang, H.2    Zhan, Y.3    Van Kirk, E.A.4    Murdoch, W.J.5
  • 74
    • 78751702579 scopus 로고    scopus 로고
    • Photothermolysis of glioblastoma stem-like cells targeted by carbon nanotubes conjugated with CD133 monoclonal antibody
    • C.H. Wang, S.H. Chiou, C.P. Chou, Y.C. Chen, Y.J. Huang, and C.A. Peng Photothermolysis of glioblastoma stem-like cells targeted by carbon nanotubes conjugated with CD133 monoclonal antibody Nanomedicine 7 2011 69 79
    • (2011) Nanomedicine , vol.7 , pp. 69-79
    • Wang, C.H.1    Chiou, S.H.2    Chou, C.P.3    Chen, Y.C.4    Huang, Y.J.5    Peng, C.A.6
  • 75
    • 78650679176 scopus 로고    scopus 로고
    • Tumor selectivity of stealth multi-functionalized superparamagnetic iron oxide nanoparticles
    • C. Fan, W. Gao, Z. Chen, H. Fan, M. Li, F. Deng, and Z. Chen Tumor selectivity of stealth multi-functionalized superparamagnetic iron oxide nanoparticles Int. J. Pharm. 404 2011 180 190
    • (2011) Int. J. Pharm. , vol.404 , pp. 180-190
    • Fan, C.1    Gao, W.2    Chen, Z.3    Fan, H.4    Li, M.5    Deng, F.6    Chen, Z.7
  • 76
    • 34249731526 scopus 로고    scopus 로고
    • Immuno gold nanocages with tailored optical properties for targeted photothermal destruction of cancer cells
    • J. Chen, D. Wang, J. Xi, L. Au, A. Siekkinen, A. Warsen, Z.Y. Li, H. Zhang, Y. Xia, and X. Li Immuno gold nanocages with tailored optical properties for targeted photothermal destruction of cancer cells Nano Lett. 7 2007 1318 1322
    • (2007) Nano Lett. , vol.7 , pp. 1318-1322
    • Chen, J.1    Wang, D.2    Xi, J.3    Au, L.4    Siekkinen, A.5    Warsen, A.6    Li, Z.Y.7    Zhang, H.8    Xia, Y.9    Li, X.10
  • 78
    • 80054713553 scopus 로고    scopus 로고
    • Dendrimer phthalocyanine-encapsulated polymeric micelle-mediated photochemical internalization extends the efficacy of photodynamic therapy and overcomes drug-resistance in vivo
    • H.L. Lu, W.J. Syu, N. Nishiyama, K. Kataoka, and P.S. Lai Dendrimer phthalocyanine-encapsulated polymeric micelle-mediated photochemical internalization extends the efficacy of photodynamic therapy and overcomes drug-resistance in vivo J. Control. Release 155 2011 458 464
    • (2011) J. Control. Release , vol.155 , pp. 458-464
    • Lu, H.L.1    Syu, W.J.2    Nishiyama, N.3    Kataoka, K.4    Lai, P.S.5
  • 79
    • 77953303740 scopus 로고    scopus 로고
    • Targeted cytosolic delivery of cell-impermeable compounds by nanoparticle-mediated, light-triggered endosome disruption
    • S. Febvay, D.M. Marini, A.M. Belcher, and D.E. Clapham Targeted cytosolic delivery of cell-impermeable compounds by nanoparticle-mediated, light-triggered endosome disruption Nano Lett. 10 2010 2211 2219
    • (2010) Nano Lett. , vol.10 , pp. 2211-2219
    • Febvay, S.1    Marini, D.M.2    Belcher, A.M.3    Clapham, D.E.4
  • 80
    • 56549121540 scopus 로고    scopus 로고
    • Synergistic cytotoxic effect of different sized ZnO nanoparticles and daunorubicin against leukemia cancer cells under UV irradiation
    • D. Guo, C. Wu, H. Jiang, Q. Li, X. Wang, and B. Chen Synergistic cytotoxic effect of different sized ZnO nanoparticles and daunorubicin against leukemia cancer cells under UV irradiation J. Photochem. Photobiol. B 93 2008 119 126
    • (2008) J. Photochem. Photobiol. B , vol.93 , pp. 119-126
    • Guo, D.1    Wu, C.2    Jiang, H.3    Li, Q.4    Wang, X.5    Chen, B.6
  • 81
    • 83555178368 scopus 로고    scopus 로고
    • Plasmonic nanobubble-enhanced endosomal escape processes for selective and guided intracellular delivery of chemotherapy to drug-resistant cancer cells
    • E.Y. Lukianova-Hleb, A. Belyanin, S. Kashinath, X. Wu, and D.O. Lapotko Plasmonic nanobubble-enhanced endosomal escape processes for selective and guided intracellular delivery of chemotherapy to drug-resistant cancer cells Biomaterials 33 2012 1821 1826
    • (2012) Biomaterials , vol.33 , pp. 1821-1826
    • Lukianova-Hleb, E.Y.1    Belyanin, A.2    Kashinath, S.3    Wu, X.4    Lapotko, D.O.5
  • 82
    • 79958206258 scopus 로고    scopus 로고
    • Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells
    • M.J. Shieh, C.Y. Hsu, L.Y. Huang, H.Y. Chen, F.H. Huang, and P.S. Lai Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells J. Control. Release 152 2011 418 425
    • (2011) J. Control. Release , vol.152 , pp. 418-425
    • Shieh, M.J.1    Hsu, C.Y.2    Huang, L.Y.3    Chen, H.Y.4    Huang, F.H.5    Lai, P.S.6
  • 83
    • 2442656249 scopus 로고    scopus 로고
    • Combined cancer therapy by micellar-encapsulated drug and ultrasound
    • N. Rapoport Combined cancer therapy by micellar-encapsulated drug and ultrasound Int. J. Pharm. 277 2004 155 162
    • (2004) Int. J. Pharm. , vol.277 , pp. 155-162
    • Rapoport, N.1
  • 85
    • 0037038301 scopus 로고    scopus 로고
    • Drug delivery in pluronic micelles: Effect of high-frequency ultrasound on drug release from micelles and intracellular uptake
    • A. Marin, H. Sun, G.A. Husseini, W.G. Pitt, D.A. Christensen, and N.Y. Rapoport Drug delivery in pluronic micelles: effect of high-frequency ultrasound on drug release from micelles and intracellular uptake J. Control. Release 84 2002 39 47
    • (2002) J. Control. Release , vol.84 , pp. 39-47
    • Marin, A.1    Sun, H.2    Husseini, G.A.3    Pitt, W.G.4    Christensen, D.A.5    Rapoport, N.Y.6
  • 86
    • 78649810957 scopus 로고    scopus 로고
    • Advances in polymeric micelles for drug delivery and tumor targeting
    • U. Kedar, P. Phutane, S. Shidhaye, and V. Kadam Advances in polymeric micelles for drug delivery and tumor targeting Nanomedicine 6 2010 714 729
    • (2010) Nanomedicine , vol.6 , pp. 714-729
    • Kedar, U.1    Phutane, P.2    Shidhaye, S.3    Kadam, V.4
  • 87
    • 33745900764 scopus 로고    scopus 로고
    • Ultrasound-enhanced chemotherapy of drug-resistant breast cancer tumors by micellar-encapsulated paclitaxel
    • B. Howard, Z. Gao, and S.W. Lee Ultrasound-enhanced chemotherapy of drug-resistant breast cancer tumors by micellar-encapsulated paclitaxel Am. J. Drug Deliv. 4 2006 97 104
    • (2006) Am. J. Drug Deliv. , vol.4 , pp. 97-104
    • Howard, B.1    Gao, Z.2    Lee, S.W.3
  • 88
    • 80054103346 scopus 로고    scopus 로고
    • Multi-modal strategies for overcoming tumor drug resistance: Hypoxia, the Warburg effect, stem cells, and multifunctional nanotechnology
    • L. Milane, S. Ganesh, S. Shah, Z.F. Duan, and M. Amiji Multi-modal strategies for overcoming tumor drug resistance: hypoxia, the Warburg effect, stem cells, and multifunctional nanotechnology J. Control. Release 155 2011 237 247
    • (2011) J. Control. Release , vol.155 , pp. 237-247
    • Milane, L.1    Ganesh, S.2    Shah, S.3    Duan, Z.F.4    Amiji, M.5
  • 89
    • 0037052062 scopus 로고    scopus 로고
    • The medicinal chemistry of multidrug resistance (MDR) reversing drugs
    • E. Teodori, S. Dei, S. Scapecchi, and F. Gualtieri The medicinal chemistry of multidrug resistance (MDR) reversing drugs Farmaco 57 2002 385 415
    • (2002) Farmaco , vol.57 , pp. 385-415
    • Teodori, E.1    Dei, S.2    Scapecchi, S.3    Gualtieri, F.4
  • 91
    • 39049089433 scopus 로고    scopus 로고
    • Targeting P-glycoprotein for effective oral anti-cancer chemotherapeutics
    • M. Bebawy, and D.M. Sze Targeting P-glycoprotein for effective oral anti-cancer chemotherapeutics Curr. Cancer Drug Targets 8 2008 47 52
    • (2008) Curr. Cancer Drug Targets , vol.8 , pp. 47-52
    • Bebawy, M.1    Sze, D.M.2
  • 92
    • 38149073214 scopus 로고    scopus 로고
    • A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs
    • K. Linnet, and T.B. Ejsing A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs Eur. Neuropsychopharmacol. 18 2008 157 169
    • (2008) Eur. Neuropsychopharmacol. , vol.18 , pp. 157-169
    • Linnet, K.1    Ejsing, T.B.2
  • 93
  • 95
    • 49649087699 scopus 로고    scopus 로고
    • Modulation of drug resistance in ovarian adenocarcinoma by enhancing intracellular ceramide using tamoxifen-loaded biodegradable polymeric nanoparticles
    • H. Devalapally, Z. Duan, M.V. Seiden, and M.M. Amiji Modulation of drug resistance in ovarian adenocarcinoma by enhancing intracellular ceramide using tamoxifen-loaded biodegradable polymeric nanoparticles Clin. Cancer Res. 14 2008 3193 3203
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3193-3203
    • Devalapally, H.1    Duan, Z.2    Seiden, M.V.3    Amiji, M.M.4
  • 96
    • 79960838501 scopus 로고    scopus 로고
    • Self-assembled nanoparticles based on hyaluronic acid-ceramide (HA-CE) and Pluronic(R) for tumor-targeted delivery of docetaxel
    • H.J. Cho, H.Y. Yoon, H. Koo, S.H. Ko, J.S. Shim, J.H. Lee, K. Kim, I.C. Kwon, and D.D. Kim Self-assembled nanoparticles based on hyaluronic acid-ceramide (HA-CE) and Pluronic(R) for tumor-targeted delivery of docetaxel Biomaterials 32 2011 7181 7190
    • (2011) Biomaterials , vol.32 , pp. 7181-7190
    • Cho, H.J.1    Yoon, H.Y.2    Koo, H.3    Ko, S.H.4    Shim, J.S.5    Lee, J.H.6    Kim, K.7    Kwon, I.C.8    Kim, D.D.9
  • 97
    • 80051544002 scopus 로고    scopus 로고
    • A pH-responsive mesoporous silica nanoparticles-based multi-drug delivery system for overcoming multi-drug resistance
    • Q. He, Y. Gao, L. Zhang, Z. Zhang, F. Gao, X. Ji, Y. Li, and J. Shi A pH-responsive mesoporous silica nanoparticles-based multi-drug delivery system for overcoming multi-drug resistance Biomaterials 32 2011 7711 7720
    • (2011) Biomaterials , vol.32 , pp. 7711-7720
    • He, Q.1    Gao, Y.2    Zhang, L.3    Zhang, Z.4    Gao, F.5    Ji, X.6    Li, Y.7    Shi, J.8
  • 99
    • 70449708980 scopus 로고    scopus 로고
    • Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel
    • C. Liu, G. Zhao, J. Liu, N. Ma, P. Chivukula, L. Perelman, K. Okada, Z. Chen, D. Gough, and L. Yu Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel J. Control. Release 140 2009 277 283
    • (2009) J. Control. Release , vol.140 , pp. 277-283
    • Liu, C.1    Zhao, G.2    Liu, J.3    Ma, N.4    Chivukula, P.5    Perelman, L.6    Okada, K.7    Chen, Z.8    Gough, D.9    Yu, L.10
  • 100
    • 33747877757 scopus 로고    scopus 로고
    • In vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and anticancer drug
    • R.I. Pakunlu, Y. Wang, M. Saad, J.J. Khandare, V. Starovoytov, and T. Minko In vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and anticancer drug J. Control. Release 114 2006 153 162
    • (2006) J. Control. Release , vol.114 , pp. 153-162
    • Pakunlu, R.I.1    Wang, Y.2    Saad, M.3    Khandare, J.J.4    Starovoytov, V.5    Minko, T.6
  • 101
    • 78650134637 scopus 로고    scopus 로고
    • Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line
    • H. Meng, M. Liong, T. Xia, Z. Li, Z. Ji, J.I. Zink, and A.E. Nel Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line ACS Nano 4 2010 4539 4550
    • (2010) ACS Nano , vol.4 , pp. 4539-4550
    • Meng, H.1    Liong, M.2    Xia, T.3    Li, Z.4    Ji, Z.5    Zink, J.I.6    Nel, A.E.7
  • 102
    • 83555179075 scopus 로고    scopus 로고
    • Mitochondrial targeting topotecan-loaded liposomes for treating drug-resistant breast cancer and inhibiting invasive metastases of melanoma
    • Y. Yu, Z.H. Wang, L. Zhang, H.J. Yao, Y. Zhang, R.J. Li, R.J. Ju, X.X. Wang, J. Zhou, N. Li, and W.L. Lu Mitochondrial targeting topotecan-loaded liposomes for treating drug-resistant breast cancer and inhibiting invasive metastases of melanoma Biomaterials 33 2012 1808 1820
    • (2012) Biomaterials , vol.33 , pp. 1808-1820
    • Yu, Y.1    Wang, Z.H.2    Zhang, L.3    Yao, H.J.4    Zhang, Y.5    Li, R.J.6    Ju, R.J.7    Wang, X.X.8    Zhou, J.9    Li, N.10    Lu, W.L.11
  • 103
    • 79957908426 scopus 로고    scopus 로고
    • The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells
    • X.X. Wang, Y.B. Li, H.J. Yao, R.J. Ju, Y. Zhang, R.J. Li, Y. Yu, L. Zhang, and W.L. Lu The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells Biomaterials 32 2011 5673 5687
    • (2011) Biomaterials , vol.32 , pp. 5673-5687
    • Wang, X.X.1    Li, Y.B.2    Yao, H.J.3    Ju, R.J.4    Zhang, Y.5    Li, R.J.6    Yu, Y.7    Zhang, L.8    Lu, W.L.9
  • 104
    • 49749101644 scopus 로고    scopus 로고
    • Pluronic block copolymers: Evolution of drug delivery concept from inert nanocarriers to biological response modifiers
    • E.V. Batrakova, and A.V. Kabanov Pluronic block copolymers: evolution of drug delivery concept from inert nanocarriers to biological response modifiers J. Control. Release 130 2008 98 106
    • (2008) J. Control. Release , vol.130 , pp. 98-106
    • Batrakova, E.V.1    Kabanov, A.V.2
  • 106
    • 77956626333 scopus 로고    scopus 로고
    • A novel paclitaxel-loaded poly(epsilon-caprolactone)/Poloxamer 188 blend nanoparticle overcoming multidrug resistance for cancer treatment
    • Y. Zhang, L. Tang, L. Sun, J. Bao, C. Song, L. Huang, K. Liu, Y. Tian, G. Tian, Z. Li, H. Sun, and L. Mei A novel paclitaxel-loaded poly(epsilon- caprolactone)/Poloxamer 188 blend nanoparticle overcoming multidrug resistance for cancer treatment Acta Biomater. 6 2010 2045 2052
    • (2010) Acta Biomater. , vol.6 , pp. 2045-2052
    • Zhang, Y.1    Tang, L.2    Sun, L.3    Bao, J.4    Song, C.5    Huang, L.6    Liu, K.7    Tian, Y.8    Tian, G.9    Li, Z.10    Sun, H.11    Mei, L.12
  • 107
    • 84655174852 scopus 로고    scopus 로고
    • Nanohybrid systems of non-ionic surfactant inserting liposomes loading paclitaxel for reversal of multidrug resistance
    • X. Ji, Y. Gao, L. Chen, Z. Zhang, Y. Deng, and Y. Li Nanohybrid systems of non-ionic surfactant inserting liposomes loading paclitaxel for reversal of multidrug resistance Int. J. Pharm. 422 2012 390 397
    • (2012) Int. J. Pharm. , vol.422 , pp. 390-397
    • Ji, X.1    Gao, Y.2    Chen, L.3    Zhang, Z.4    Deng, Y.5    Li, Y.6
  • 108
    • 79951576538 scopus 로고    scopus 로고
    • Multifunctional pluronic P123/F127 mixed polymeric micelles loaded with paclitaxel for the treatment of multidrug resistant tumors
    • W. Zhang, Y. Shi, Y. Chen, J. Ye, X. Sha, and X. Fang Multifunctional pluronic P123/F127 mixed polymeric micelles loaded with paclitaxel for the treatment of multidrug resistant tumors Biomaterials 32 2011 2894 2906
    • (2011) Biomaterials , vol.32 , pp. 2894-2906
    • Zhang, W.1    Shi, Y.2    Chen, Y.3    Ye, J.4    Sha, X.5    Fang, X.6
  • 109
    • 76749102351 scopus 로고    scopus 로고
    • An anticancer drug delivery system based on surfactant-templated mesoporous silica nanoparticles
    • Q. He, J. Shi, F. Chen, M. Zhu, and L. Zhang An anticancer drug delivery system based on surfactant-templated mesoporous silica nanoparticles Biomaterials 31 2010 3335 3346
    • (2010) Biomaterials , vol.31 , pp. 3335-3346
    • He, Q.1    Shi, J.2    Chen, F.3    Zhu, M.4    Zhang, L.5
  • 110
    • 0015349672 scopus 로고
    • Potentiation of drug effect by Tween 80 in Chinese hamster cells resistant to actinomycin D and daunomycin
    • H. Riehm, and J.L. Biedler Potentiation of drug effect by Tween 80 in Chinese hamster cells resistant to actinomycin D and daunomycin Cancer Res. 32 1972 1195 1200
    • (1972) Cancer Res. , vol.32 , pp. 1195-1200
    • Riehm, H.1    Biedler, J.L.2
  • 111
    • 0027304139 scopus 로고
    • Interaction of multidrug-resistant Chinese hamster ovary cells with amphiphiles
    • D.W. Loe, and F.J. Sharom Interaction of multidrug-resistant Chinese hamster ovary cells with amphiphiles Br. J. Cancer 68 1993 342 351
    • (1993) Br. J. Cancer , vol.68 , pp. 342-351
    • Loe, D.W.1    Sharom, F.J.2
  • 112
    • 49549170184 scopus 로고
    • Poly[N-(2-hydroxypropyl)methacrylamide]. I. Radical polymerization and copolymerization
    • J. Kopecek, and H. Bazilova Poly[N-(2-hydroxypropyl)methacrylamide]. I. Radical polymerization and copolymerization Eur. Polym. 9 1973 7 14
    • (1973) Eur. Polym. , vol.9 , pp. 7-14
    • Kopecek, J.1    Bazilova, H.2
  • 113
    • 0017089608 scopus 로고
    • New types of synthetic infusion solutions. III. Elimination and retention of poly-[N-(2-hydroxypropyl)methacrylamide] in a test organism
    • L. Sprincl, J. Exner, O. Sterba, and J. Kopecek New types of synthetic infusion solutions. III. Elimination and retention of poly-[N-(2-hydroxypropyl) methacrylamide] in a test organism J. Biomed. Mater. Res. 10 1976 953 963
    • (1976) J. Biomed. Mater. Res. , vol.10 , pp. 953-963
    • Sprincl, L.1    Exner, J.2    Sterba, O.3    Kopecek, J.4
  • 114
    • 79955130099 scopus 로고    scopus 로고
    • Enhanced anti-tumor activity and safety profile of targeted nano-scaled HPMA copolymer-alendronate-TNP-470 conjugate in the treatment of bone malignances
    • E. Segal, H. Pan, L. Benayoun, P. Kopeckova, Y. Shaked, J. Kopecek, and R. Satchi-Fainaro Enhanced anti-tumor activity and safety profile of targeted nano-scaled HPMA copolymer-alendronate-TNP-470 conjugate in the treatment of bone malignances Biomaterials 32 2011 4450 4463
    • (2011) Biomaterials , vol.32 , pp. 4450-4463
    • Segal, E.1    Pan, H.2    Benayoun, L.3    Kopeckova, P.4    Shaked, Y.5    Kopecek, J.6    Satchi-Fainaro, R.7
  • 116
    • 38749144812 scopus 로고    scopus 로고
    • Enhanced antitumor activity of combinations of free and HPMA copolymer-bound drugs
    • J. Hongrapipat, P. Kopeckova, S. Prakongpan, and J. Kopecek Enhanced antitumor activity of combinations of free and HPMA copolymer-bound drugs Int. J. Pharm. 351 2008 259 270
    • (2008) Int. J. Pharm. , vol.351 , pp. 259-270
    • Hongrapipat, J.1    Kopeckova, P.2    Prakongpan, S.3    Kopecek, J.4
  • 117
    • 79957446637 scopus 로고    scopus 로고
    • Anticancer and antiangiogenic activity of HPMA copolymer- aminohexylgeldanamycin-RGDfK conjugates for prostate cancer therapy
    • K. Greish, A. Ray, H. Bauer, N. Larson, A. Malugin, D. Pike, M. Haider, and H. Ghandehari Anticancer and antiangiogenic activity of HPMA copolymer-aminohexylgeldanamycin-RGDfK conjugates for prostate cancer therapy J. Control. Release 151 2011 263 270
    • (2011) J. Control. Release , vol.151 , pp. 263-270
    • Greish, K.1    Ray, A.2    Bauer, H.3    Larson, N.4    Malugin, A.5    Pike, D.6    Haider, M.7    Ghandehari, H.8
  • 118
    • 84856619301 scopus 로고    scopus 로고
    • Synthesis and in vitro anti-tumor activity of novel HPMA copolymer-drug conjugates with potential cell surface targeting property for carcinoma cells
    • Q. Xiang, Y. Yang, Z. Zhou, D. Zhou, Y. Jin, Z. Zhang, and Y. Huang Synthesis and in vitro anti-tumor activity of novel HPMA copolymer-drug conjugates with potential cell surface targeting property for carcinoma cells Eur. J. Pharm. Biopharm. 80 2012 379 386
    • (2012) Eur. J. Pharm. Biopharm. , vol.80 , pp. 379-386
    • Xiang, Q.1    Yang, Y.2    Zhou, Z.3    Zhou, D.4    Jin, Y.5    Zhang, Z.6    Huang, Y.7
  • 119
    • 84855754743 scopus 로고    scopus 로고
    • Treatment of prostate carcinoma with (galectin-3)-targeted HPMA copolymer-(G3-C12)-5-Fluorouracil conjugates
    • Y. Yang, Z. Zhou, S. He, T. Fan, Y. Jin, X. Zhu, C. Chen, Z.R. Zhang, and Y. Huang Treatment of prostate carcinoma with (galectin-3)-targeted HPMA copolymer-(G3-C12)-5-Fluorouracil conjugates Biomaterials 33 2012 2260 2271
    • (2012) Biomaterials , vol.33 , pp. 2260-2271
    • Yang, Y.1    Zhou, Z.2    He, S.3    Fan, T.4    Jin, Y.5    Zhu, X.6    Chen, C.7    Zhang, Z.R.8    Huang, Y.9
  • 123
    • 80054115169 scopus 로고    scopus 로고
    • HPMA-oligolysine copolymers for gene delivery: Optimization of peptide length and polymer molecular weight
    • R.N. Johnson, D.S. Chu, J. Shi, J.G. Schellinger, P.M. Carlson, and S.H. Pun HPMA-oligolysine copolymers for gene delivery: optimization of peptide length and polymer molecular weight J. Control. Release 155 2011 303 311
    • (2011) J. Control. Release , vol.155 , pp. 303-311
    • Johnson, R.N.1    Chu, D.S.2    Shi, J.3    Schellinger, J.G.4    Carlson, P.M.5    Pun, S.H.6
  • 124
    • 84861215176 scopus 로고    scopus 로고
    • Preparation and characterization of guanidinated N-3-aminopropyl methacrylamide-N-2-hydroxypropyl methacrylamide copolymers as gene delivery carriers
    • Z. Qin, W. Liu, L. Guo, and X. Li Preparation and characterization of guanidinated N-3-aminopropyl methacrylamide-N-2-hydroxypropyl methacrylamide copolymers as gene delivery carriers J. Control. Release 152 Suppl. 1 2011 e168 e170
    • (2011) J. Control. Release , vol.152 , Issue.SUPPL. 1
    • Qin, Z.1    Liu, W.2    Guo, L.3    Li, X.4
  • 126
    • 34548015449 scopus 로고    scopus 로고
    • Star-shaped immunoglobulin-containing HPMA-based conjugates with doxorubicin for cancer therapy
    • T. Etrych, T. Mrkvan, B. Rihova, and K. Ulbrich Star-shaped immunoglobulin-containing HPMA-based conjugates with doxorubicin for cancer therapy J. Control. Release 122 2007 31 38
    • (2007) J. Control. Release , vol.122 , pp. 31-38
    • Etrych, T.1    Mrkvan, T.2    Rihova, B.3    Ulbrich, K.4
  • 127
    • 70349987594 scopus 로고    scopus 로고
    • Development of HPMA copolymer-anticancer conjugates: Clinical experience and lessons learnt
    • R. Duncan Development of HPMA copolymer-anticancer conjugates: clinical experience and lessons learnt Adv. Drug Deliv. Rev. 61 2009 1131 1148
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 1131-1148
    • Duncan, R.1
  • 128
    • 79960103171 scopus 로고    scopus 로고
    • Conformational consequences of cooperative binding of a coiled-coil peptide motif to poly(N-(2-hydroxypropyl) methacrylamide) HPMA copolymers
    • P.C. Griffiths, A. Paul, B. Apostolovic, H.A. Klok, E. de Luca, S.M. King, and R.K. Heenan Conformational consequences of cooperative binding of a coiled-coil peptide motif to poly(N-(2-hydroxypropyl) methacrylamide) HPMA copolymers J. Control. Release 153 2011 173 179
    • (2011) J. Control. Release , vol.153 , pp. 173-179
    • Griffiths, P.C.1    Paul, A.2    Apostolovic, B.3    Klok, H.A.4    De Luca, E.5    King, S.M.6    Heenan, R.K.7
  • 129
    • 34547679654 scopus 로고    scopus 로고
    • Antitumor activity of new liposomal prodrug of mitomycin C in multidrug resistant solid tumor: Insights of the mechanism of action
    • S. Zalipsky, M. Saad, R. Kiwan, E. Ber, N. Yu, and T. Minko Antitumor activity of new liposomal prodrug of mitomycin C in multidrug resistant solid tumor: insights of the mechanism of action J. Drug Target 15 2007 518 530
    • (2007) J. Drug Target , vol.15 , pp. 518-530
    • Zalipsky, S.1    Saad, M.2    Kiwan, R.3    Ber, E.4    Yu, N.5    Minko, T.6
  • 130
    • 0345367901 scopus 로고    scopus 로고
    • HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line
    • T. Minko, P. Kopeckova, V. Pozharov, and J. Kopecek HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line J. Control. Release 54 1998 223 233
    • (1998) J. Control. Release , vol.54 , pp. 223-233
    • Minko, T.1    Kopeckova, P.2    Pozharov, V.3    Kopecek, J.4
  • 131
    • 0344142519 scopus 로고    scopus 로고
    • Chronic exposure to HPMA copolymer-bound adriamycin does not induce multidrug resistance in a human ovarian carcinoma cell line
    • T. Minko, P. Kopeckova, and J. Kopecek Chronic exposure to HPMA copolymer-bound adriamycin does not induce multidrug resistance in a human ovarian carcinoma cell line J. Control. Release 59 1999 133 148
    • (1999) J. Control. Release , vol.59 , pp. 133-148
    • Minko, T.1    Kopeckova, P.2    Kopecek, J.3
  • 132
    • 0034333734 scopus 로고    scopus 로고
    • Chronic exposure of human ovarian carcinoma cells to free or HPMA copolymer-bound mesochlorin e6 does not induce P-glycoprotein-mediated multidrug resistance
    • M. Tijerina, K.D. Fowers, P. Kopeckova, and J. Kopecek Chronic exposure of human ovarian carcinoma cells to free or HPMA copolymer-bound mesochlorin e6 does not induce P-glycoprotein-mediated multidrug resistance Biomaterials 21 2000 2203 2210
    • (2000) Biomaterials , vol.21 , pp. 2203-2210
    • Tijerina, M.1    Fowers, K.D.2    Kopeckova, P.3    Kopecek, J.4
  • 133
    • 0035962380 scopus 로고    scopus 로고
    • Preliminary evaluation of caspasesdependent apoptosis signaling pathways of free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells
    • T. Minko, P. Kopeckova, and J. Kopecek Preliminary evaluation of caspasesdependent apoptosis signaling pathways of free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells J. Control. Release 71 2001 227 237
    • (2001) J. Control. Release , vol.71 , pp. 227-237
    • Minko, T.1    Kopeckova, P.2    Kopecek, J.3
  • 134
    • 75749106657 scopus 로고    scopus 로고
    • HPMA copolymers for modulating cellular signaling and overcoming multidrug resistance
    • T. Minko HPMA copolymers for modulating cellular signaling and overcoming multidrug resistance Adv. Drug Deliv. Rev. 62 2010 192 202
    • (2010) Adv. Drug Deliv. Rev. , vol.62 , pp. 192-202
    • Minko, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.