Degradable Poly(β-amino ester) nanoparticles for cancer cytoplasmic drug delivery

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 5, Issue 2, 2009, Pages 192-201

  Shen, Youqing ^a,b   Tang, Huadong ^b   Zhan, Yihong ^b   Van Kirk, Edward A ^c   Murdoch, William J ^c  

^a Department of Chemical and Biochemical Engineering   (China)

^b UNIVERSITY OF WYOMING   (United States)

^c UNIVERSITY OF WYOMING   (United States)

Author keywords

Cytoplasmic drug delivery; Graft polymers; Lysosomal escape; pH responsive nanoparticles

Indexed keywords

AMINO ESTERS; CAMPTOTHECIN; CANCER CELLS; CONDENSATION POLYMERIZATION; CYTOPLASMIC DRUG DELIVERY; CYTOSOL; DIACRYLATE; DRUG CARRIER; DRUG RESISTANCE; GRAFT POLYMERS; LYSOSOMAL ESCAPE; MACROMONOMER; OVARIAN CANCER CELLS; PH-RESPONSIVE; PH-RESPONSIVE NANOPARTICLES; SIDE CHAINS; THERAPEUTIC EFFICACY;

AMINATION; AMINES; BODY FLUIDS; CELL MEMBRANES; DRUG DELIVERY; ESTERIFICATION; ESTERS; ETHYLENE GLYCOL; GRAFT COPOLYMERS; GRAFTING (CHEMICAL); NANOPARTICLES; POLYCONDENSATION; POLYETHYLENE OXIDES; POLYMERS; SYNTHESIS (CHEMICAL);

POLYETHYLENE GLYCOLS;

ACRYLIC ACID; CAMPTOTHECIN; COPOLYMER; MACROGOL DERIVATIVE; NANOPARTICLE; PACLITAXEL; PIPERAZINE; POLY(BETA MINO ESTER CO ETHYLENE GLYCOL); UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIODEGRADABILITY; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; CYTOPLASM; CYTOSOL; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG SYNTHESIS; ENDOSOME; HEMOLYSIS; HUMAN; HUMAN CELL; LYSOSOME; MICELLE; NANOENCAPSULATION; PH; POLYMERIZATION; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CELL LINE, TUMOR; CYTOSOL; DRUG CARRIERS; ENDOSOMES; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, CONFOCAL; NANOPARTICLES; PIPERAZINES; POLYETHYLENE GLYCOLS; POLYMERS; SHEEP;

EID: 67349140207     PISSN: 15499634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nano.2008.09.003     Document Type: Article

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