Reversion of multidrug resistance by tumor targeted delivery of antisense oligodeoxynucleotides in hydroxypropyl-chitosan nanoparticles

Biomaterials

Volumn 31, Issue 15, 2010, Pages 4426-4433

  Wang, Jiaqi ^a   Tao, Xinyi ^a   Zhang, Yufei ^a   Wei, Dongzhi ^a   Ren, Yuhong ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Antisense oligodeoxynucleotides; Hydroxypropyl chitosan nanoparticles; Multidrug resistance; Tumor targeted

Indexed keywords

ANTI-CANCER THERAPIES; ANTISENSE AGENT; ANTISENSE OLIGODEOXYNUCLEOTIDES; ANTITUMOR EFFECT; CANCER CELLS; CHARGE RATIO; CHITOSAN NANOPARTICLES; DRUG RESISTANCE; FOLIC ACIDS; GENE DELIVERY; GENE LEVELS; IN-VITRO; LOADING EFFICIENCY; MULTIDRUG RESISTANCE; NONVIRAL VECTORS; SPECTROFLUORIMETRY; TARGETED DELIVERY; TUMOR TARGETED DELIVERY; VIVO STUDIES;

CHITIN; CHITOSAN; GENE THERAPY; GENE TRANSFER; ORGANIC ACIDS; SULFUR COMPOUNDS; TUMORS;

NANOPARTICLES;

ANTISENSE OLIGODEOXYNUCLEOTIDE; BUFFER; DOXORUBICIN; FOLATE RECEPTOR; FOLIC ACID; GLYCOPROTEIN P; HYDROXYPROPYL CHITOSAN NANOPARTICLE; NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG BINDING; DRUG RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE STRAIN; MULTIDRUG RESISTANCE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SPECTROFLUOROMETRY; TUMOR RESISTANCE;

ANIMALS; CELL LINE, TUMOR; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; GENE THERAPY; GENETIC VECTORS; HUMANS; MATERIALS TESTING; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOPARTICLES; OLIGONUCLEOTIDES, ANTISENSE; RANDOM ALLOCATION;

MUS;

EID: 77949656381     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.02.007     Document Type: Article

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