Conformational consequences of cooperative binding of a coiled-coil peptide motif to poly(N-(2-hydroxypropyl) methacrylamide) HPMA copolymers

Journal of Controlled Release

Volumn 153, Issue 2, 2011, Pages 173-179

  Griffiths, Peter C ^a   Paul, Alison ^a   Apostolovic, Bojana ^b   Klok, Harm Anton ^b   De Luca, Edoardo ^a   King, Stephen M ^c   Heenan, Richard K ^c  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b EPFL   (Switzerland)

^c RUTHERFORD APPLETON LABORATORY   (United Kingdom)

Author keywords

Coiled coil motif; Endocytosis; Peptide delivery; Small angle neutron scattering; Solution conformation

Indexed keywords

COILED COIL; ENDOCYTOSIS; PEPTIDE DELIVERY; SMALL-ANGLE NEUTRON SCATTERING; SOLUTION CONFORMATION;

BIOCHEMISTRY; CONFORMATIONS; COPOLYMERIZATION; COPOLYMERS; DRUG DELIVERY; FUNCTIONAL POLYMERS; HYDROPHOBICITY; MOLECULAR BIOLOGY; NEUTRON SCATTERING; PH EFFECTS;

PEPTIDES;

METHOTREXATE; POLY[N (2 HYDROXYPROPYL)METHACRYLAMIDE];

ARTICLE; DRUG DELIVERY SYSTEM; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN MOTIF; SMALL ANGLE SCATTERING;

HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; METHACRYLATES; MOLECULAR CONFORMATION; NEUTRON DIFFRACTION; PEPTIDES; PROTEIN CONFORMATION; SCATTERING, SMALL ANGLE;

EID: 79960103171     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.03.030     Document Type: Article

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