New trifluoromethyl triazolopyrimidines as Anti-Plasmodium falciparum agents

Molecules

Volumn 17, Issue 7, 2012, Pages 8285-8302

  Boechat, Núbia ^a   Pinheiro, Luiz C S ^a   Silva, Thiago S ^a,b   Aguiar, Anna C C ^a,c   Carvalho, Alcione S ^a   Bastos, Monica M ^a   Costa, Carolina C P ^a   Pinheiro, Sergio ^d   Pinto, Angelo C ^b   Mendonça, Jorge S ^a   Dutra, Karen D B ^a,d   Valverde, Alessandra L ^d   Santos Filho, Osvaldo A ^a   Ceravolo, Isabela P ^a   Krettli, Antoniana U ^a,c  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^d FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

Malaria; P. falciparum; PfDHODH; Triazolopyrimidine; Trifluoromethyl

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; PYRIMIDINE; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; QUINOLINE DERIVATIVE;

ARTICLE; CELL DEATH; CELL STRAIN HEPG2; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; DRUG RESISTANCE; ERYTHROCYTE; HUMAN; PARASITOLOGY; PLASMODIUM FALCIPARUM; SYNTHESIS;

ANTIMALARIALS; AZOLES; CELL DEATH; CHLOROQUINE; DRUG RESISTANCE; ERYTHROCYTES; HEP G2 CELLS; HUMANS; MODELS, MOLECULAR; PLASMODIUM FALCIPARUM; PYRIMIDINES; QUINOLINES;

EID: 84864627968     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17078285     Document Type: Article

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