Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 18, 2009, Pages 6560-6566

  Iwaniuk, Daniel P ^a   Whetmore, Eric D ^a   Rosa, Nicholas ^a   Ekoue Kovi, Kekeli ^a   Alumasa, John ^a   de Dios, Angel C ^a   Roepe, Paul D ^a,b   Wolf, Christian ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

4 Alkoxyquinolines; 4 Aminoquinolines; Chloroquine; Malaria; Resistance index

Indexed keywords

1 (7 CHLORO 4 O QUINOLYL) N' ETHYL N' (3 DIETHYLAMINOPROPYL) 3 AMINOPROPANE; CHLOROQUINE; N (7 CHLORO 4 QUINOLYL) N' ETHYL N' (2 DIETHYLAMINOETHYL) 1,2 DIAMINOETHANE; N (7 CHLORO 4 QUINOLYL) N' ETHYL N' (4 DIETHYLAMINOBUTYL) 1,2 DIAMINOETHANE; N (7 CHLORO 4 QUINOLYL) N' ETHYL N' (5 DIETHYLAMINOPENTYL) 1,2 DIAMINOETHANE; N (7 CHLORO 4 QUINOLYL) N' ETHYL N' (6 DIETHYLAMINOHEXYL) 1,2 DIAMINOETHANE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PLASMODIUM FALCIPARUM;

AMINOQUINOLINES; ANIMALS; ANTIMALARIALS; CHLOROQUINE; INHIBITORY CONCENTRATION 50; MALARIA, FALCIPARUM; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 69249157364     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.08.003     Document Type: Article

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