Synthesis and evaluation of phenylequine for antimalarial activity in vitro and in vivo

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 1078-1080

  Blackie, Margaret A L ^a   Yardley, Vanessa ^b   Chibale, Kelly ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Antiplasmodial; Biological activity; Bioorganic chemistry; Chloroquine analogue; Ferroquine

Indexed keywords

4 AMINOQUINOLINE; ANTIMALARIAL AGENT; CHLOROQUINE; FERROQUINE; PHENYLEQUINE; SODIUM CHLORIDE; UNCLASSIFIED DRUG; 4-AMINOQUINOLINE; AMINOQUINOLINE DERIVATIVE;

ANIMAL CELL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM YOELII; CELL LINE; COMPARATIVE STUDY; DRUG EFFECTS; DRUG SCREENING; PHYSIOLOGY; PLASMODIUM FALCIPARUM; PROCEDURES; SYNTHESIS;

PLASMODIUM BERGHEI; PLASMODIUM YOELII;

AMINOQUINOLINES; ANTIMALARIALS; CELL LINE; DRUG EVALUATION, PRECLINICAL; HUMANS; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII;

EID: 74049104919     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.030     Document Type: Article

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