Antileishmanial pyrazolopyridine derivatives: Synthesis and structure-activity relationship analysis

Journal of Medicinal Chemistry

Volumn 47, Issue 22, 2004, Pages 5427-5432

  De Mello, Heloisa ^a   Echevarria, Aurea ^a   Bernardino, Alice M ^b   Canto Cavalheiro, Marilene ^c   Leon, Leonor L ^c  

^a FEDERAL RURAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4' CHLOROPHENYLAMINO) 5 CARBETHOXY 1,3 DIMETHYL 1H PYRAZOLO[3,4 B]PYRIDINE; 4 (4' HYDROXYPHENYLAMINO) 5 CARBETHOXY 1,3 DIMETHYL 1H PYRAZOLO[3,4 B]PYRIDINE; 4 (PHENYLAMINO) 5 CARBETHOXY 1,3 DIMETHYL 1H PYRAZOLO[3,4 B]PYRIDINE; 4 CHLORO 1H PYRAZOLO[3,4 B]PYRIDINE; AMODIAQUINE; ANILINE DERIVATIVE; ANTILEISHMANIAL AGENT; CARBOXYLIC ACID DERIVATIVE; CHLORINE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONFORMATION; DRUG SYNTHESIS; HYDROPHOBICITY; IC 50; LEISHMANIA; MANNICH REACTION; MOLECULAR MODEL; NONHUMAN; POLYMERIZATION; PROMASTIGOTE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOSPECIFICITY;

ANIMALS; LEISHMANIA; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PYRAZOLES; PYRIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS;

EID: 6044272951     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0401006     Document Type: Article

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