Synthesis and antimalarial activity of new analogues of amodiaquine

European Journal of Medicinal Chemistry

Volumn 43, Issue 2, 2008, Pages 252-260

  Delarue Cochin, Sandrine ^a   Paunescu, Emilia ^a   Maes, Louis ^b   Mouray, Elisabeth ^c   Sergheraert, Christian ^a   Grellier, Philippe ^c   Melnyk, Patricia ^a  

^a CNRS   (France)

^b Virco BVBA   (Belgium)

^c MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

4 Aminoquinolines; Amodiaquine; Antimalarials; Drug design; Plasmodium falciparum

Indexed keywords

4 AMINOQUINOLINE DERIVATIVE; AMODIAQUINE; CHLOROQUINE; N (7 CHLOROQUINOLIN 4 YL) 5 DIETHYLAMINOMETHYL 1,3 PHENYLENEDIAMINE; PHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; HYDROGEN BOND; IN VITRO STUDY; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PROTOZOON; SURVIVAL TIME;

AMODIAQUINE; ANIMALS; ANTIMALARIALS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PLASMODIUM BERGHEI;

EID: 38949114574     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.03.008     Document Type: Article

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