Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver

Journal of Proteome Research

Volumn 11, Issue 8, 2012, Pages 4052-4064

  Rashid, S Tamir ^a,b,d   Humphries, Jonathan D ^a,b   Byron, Adam ^a,b   Dhar, Ameet ^b   Askari, Janet A ^a,b   Selley, Julian N ^b   Knight, David ^b   Goldin, Robert D ^c   Thursz, Mark ^c   Humphries, Martin J ^a,b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

CYR61; extracellular matrix; fibrosis; hepatic stellate cells; liver; LX 2; proteomics; Wnt 5a

Indexed keywords

CYSTEINE RICH PROTEIN 61; WNT5A PROTEIN;

ARTICLE; CELL TYPE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LIVER FIBROSIS; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEOMICS; STELLATE CELL;

ANIMALS; CELL LINE; CLUSTER ANALYSIS; CYSTEINE-RICH PROTEIN 61; EXTRACELLULAR MATRIX; FIBROBLASTS; HEPATIC STELLATE CELLS; HUMANS; LIVER CIRRHOSIS; MICE; MICE, INBRED C57BL; PROTEIN INTERACTION MAPPING; PROTEIN INTERACTION MAPS; PROTEOME; PROTEOMICS; PROTO-ONCOGENE PROTEINS; WNT PROTEINS;

MURINAE;

EID: 84864591367     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr3000927     Document Type: Article

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