메뉴 건너뛰기




Volumn 86, Issue 11, 2006, Pages 1149-1160

Agrin, a novel basement membrane component in human and rat liver, accumulates in cirrhosis and hepatocellular carcinoma

Author keywords

Agrin; Basement membrane; Cirrhosis; Heparan sulfate proteoglycan; Hepatocellular carcinoma; Neoangiogenesis

Indexed keywords

AGRIN; CD51 ANTIGEN; GROWTH FACTOR;

EID: 33750367402     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700475     Document Type: Article
Times cited : (68)

References (36)
  • 1
    • 0029865809 scopus 로고    scopus 로고
    • Expression of extracellular matrix proteoglycans perlecan and decorin in carbon-tetrachloride-injured rat liver and in isolated liver cells
    • Gallai M, Kovalszky I, Knittel T, et al. Expression of extracellular matrix proteoglycans perlecan and decorin in carbon-tetrachloride-injured rat liver and in isolated liver cells. Am J Pathol 1996;148:1463-1471.
    • (1996) Am J Pathol , vol.148 , pp. 1463-1471
    • Gallai, M.1    Kovalszky, I.2    Knittel, T.3
  • 3
    • 17944362596 scopus 로고    scopus 로고
    • Expression of decorin, transforming growth factor-beta 1, tissue inhibitor metalloproteinase 1 and 2, and type IV collagenases in chronic hepatitis
    • Dudas J, Kovalszky I, Gallai M, et al. Expression of decorin, transforming growth factor-beta 1, tissue inhibitor metalloproteinase 1 and 2, and type IV collagenases in chronic hepatitis. Am J Clin Pathol 2001;115:725-735.
    • (2001) Am J Clin Pathol , vol.115 , pp. 725-735
    • Dudas, J.1    Kovalszky, I.2    Gallai, M.3
  • 4
    • 0031428608 scopus 로고    scopus 로고
    • Expression of biglycan, decorin and proteoglycan-100/CSF-1 in normal and fibrotic human liver
    • Hogemann B, Edel G, Schwarz K, et al. Expression of biglycan, decorin and proteoglycan-100/CSF-1 in normal and fibrotic human liver. Pathol Res Pract 1997;193:747-751.
    • (1997) Pathol Res Pract , vol.193 , pp. 747-751
    • Hogemann, B.1    Edel, G.2    Schwarz, K.3
  • 5
    • 0027902874 scopus 로고
    • Potential markers (enzymes, proteoglycans) for human liver tumors
    • Kovalszky I, Schaff Z, Jeney A. Potential markers (enzymes, proteoglycans) for human liver tumors. Acta Biomed Ateneo Parmense 1993;64:157-163.
    • (1993) Acta Biomed Ateneo Parmense , vol.64 , pp. 157-163
    • Kovalszky, I.1    Schaff, Z.2    Jeney, A.3
  • 6
    • 0027441601 scopus 로고
    • Distribution and origin of the basement membrane component perlecan in rat liver and primary hepatocyte culture
    • Rescan PY, Loreal O, Hassell JR, et al. Distribution and origin of the basement membrane component perlecan in rat liver and primary hepatocyte culture. Am J Pathol 1993;142:199-208.
    • (1993) Am J Pathol , vol.142 , pp. 199-208
    • Rescan, P.Y.1    Loreal, O.2    Hassell, J.R.3
  • 7
    • 0028579734 scopus 로고
    • Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis
    • Aviezer D, Hecht D, Safran M, et al. Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis. Cell 1994;79:1005-1013.
    • (1994) Cell , vol.79 , pp. 1005-1013
    • Aviezer, D.1    Hecht, D.2    Safran, M.3
  • 9
    • 0033516558 scopus 로고    scopus 로고
    • The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins
    • Iozzo RV. The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins. J Biol Chem 1999;274:18843-18846.
    • (1999) J Biol Chem , vol.274 , pp. 18843-18846
    • Iozzo, R.V.1
  • 10
    • 0037380541 scopus 로고    scopus 로고
    • New insights into the roles of agrin
    • Bezakova G, Ruegg MA. New insights into the roles of agrin. Nature Rev Mol Cell Biol 2003;4:295-309.
    • (2003) Nature Rev Mol Cell Biol , vol.4 , pp. 295-309
    • Bezakova, G.1    Ma, R.2
  • 11
    • 0032815533 scopus 로고    scopus 로고
    • Recent insights into the structure and functions of heparan sulfate proteoglycans in the human glomerular basement membrane
    • Groffen AJ, Veerkamp JH, Monnens LA, et al. Recent insights into the structure and functions of heparan sulfate proteoglycans in the human glomerular basement membrane. Nephrol Dial Transplant 1999;14: 2119-2129.
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 2119-2129
    • Groffen, A.J.1    Veerkamp, J.H.2    Monnens, L.A.3
  • 12
    • 0031982584 scopus 로고    scopus 로고
    • Agrin is a high-affinity binding protein of dystroglycan in non-muscle tissue
    • Gesemann M, Brancaccio A, Schumacher B, et al. Agrin is a high-affinity binding protein of dystroglycan in non-muscle tissue. J Biol Chem 1998;273:600-605.
    • (1998) J Biol Chem , vol.273 , pp. 600-605
    • Gesemann, M.1    Brancaccio, A.2    Schumacher, B.3
  • 13
    • 0030728897 scopus 로고    scopus 로고
    • Integrins mediate adhesion to agrin and modulate agrin signaling
    • Martin PT, Sanes JR. Integrins mediate adhesion to agrin and modulate agrin signaling. Development 1997;124:3909-3917.
    • (1997) Development , vol.124 , pp. 3909-3917
    • Martin, P.T.1    Sanes, J.R.2
  • 14
    • 0036796801 scopus 로고    scopus 로고
    • Mapping sites responsible for interactions of agrin with neurons
    • Burgess RW, Dickman DK, Nunez L, et al. Mapping sites responsible for interactions of agrin with neurons. J Neurochem 2002;83:271-284.
    • (2002) J Neurochem , vol.83 , pp. 271-284
    • Burgess, R.W.1    Dickman, D.K.2    Nunez, L.3
  • 16
    • 0030330931 scopus 로고    scopus 로고
    • Agrin: An extracellular matrix heparan sulfate proteoglycan involved in cell interactions and synaptogenesis
    • Cole GJ, Halfter W. Agrin: an extracellular matrix heparan sulfate proteoglycan involved in cell interactions and synaptogenesis. Perspect Dev Neurobiol 1996;3:359-371.
    • (1996) Perspect Dev Neurobiol , vol.3 , pp. 359-371
    • Cole, G.J.1    Halfter, W.2
  • 17
    • 0036794744 scopus 로고    scopus 로고
    • Agrin in the developing CNS: New roles for a synapse organizer
    • Kroger S, Schroder JE. Agrin in the developing CNS: new roles for a synapse organizer. News Physiol Sci 2002;17:207-212.
    • (2002) News Physiol Sci , vol.17 , pp. 207-212
    • Kroger, S.1    Schroder, J.E.2
  • 18
    • 0031015296 scopus 로고    scopus 로고
    • Agrin accumulates in the brain microvascular basal lamina during development of the blood-brain barrier
    • Barber AJ, Lieth E. Agrin accumulates in the brain microvascular basal lamina during development of the blood-brain barrier. Dev Dyn 1997;208:62-74.
    • (1997) Dev Dyn , vol.208 , pp. 62-74
    • Barber, A.J.1    Lieth, E.2
  • 19
    • 0035369125 scopus 로고    scopus 로고
    • Physiological regulation of the immunological synapse by agrin
    • Khan AA, Bose C, Yam LS, et al. Physiological regulation of the immunological synapse by agrin. Science 2001;292:1681-1686.
    • (2001) Science , vol.292 , pp. 1681-1686
    • Khan, A.A.1    Bose, C.2    Yam, L.S.3
  • 20
    • 15644366697 scopus 로고    scopus 로고
    • Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane
    • Groffen AJ, Ruegg MA, Dijkman H, et al. Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane. J Histochem Cytochem 1998;46:19-27.
    • (1998) J Histochem Cytochem , vol.46 , pp. 19-27
    • Groffen, A.J.1    Ruegg, M.A.2    Dijkman, H.3
  • 21
    • 0032742051 scopus 로고    scopus 로고
    • Rat liver myofibroblasts and hepatic stellate cells: Different cell populations of the fibroblast lineage with fibrogenic potential
    • Knittel T, Kobold D, Saile B, et al. Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential. Gastroenterology 1999;117:1205-1221.
    • (1999) Gastroenterology , vol.117 , pp. 1205-1221
    • Knittel, T.1    Kobold, D.2    Saile, B.3
  • 22
    • 5444261094 scopus 로고    scopus 로고
    • The stroma reaction myofibroblast: A key player in the control of tumor cell behavior
    • Desmouliere A, Guyot C, Gabbiani G. The stroma reaction myofibroblast: a key player in the control of tumor cell behavior. Int J Dev Biol 2004;48:509-517.
    • (2004) Int J Dev Biol , vol.48 , pp. 509-517
    • Desmouliere, A.1    Guyot, C.2    Gabbiani, G.3
  • 23
    • 0028071201 scopus 로고
    • Simultaneous induction of liver cirrhosis and hepatocellular carcinomas in F-344 rats: Establishment of a short hepatocarcinogenesis model
    • Zalatnai A, Lapis K. Simultaneous induction of liver cirrhosis and hepatocellular carcinomas in F-344 rats: establishment of a short hepatocarcinogenesis model. Exp Toxicol Pathol 1994;46:215-222.
    • (1994) Exp Toxicol Pathol , vol.46 , pp. 215-222
    • Zalatnai, A.1    Lapis, K.2
  • 24
    • 0030157557 scopus 로고    scopus 로고
    • Glial fibrillary acidic protein-a cell type specific marker for Ito cells in vivo and in vitro
    • Neubauer K, Knittel T, Aurisch S, et al. Glial fibrillary acidic protein-a cell type specific marker for Ito cells in vivo and in vitro. J Hepatol 1996;24:719-730.
    • (1996) J Hepatol , vol.24 , pp. 719-730
    • Neubauer, K.1    Knittel, T.2    Aurisch, S.3
  • 25
    • 0036076876 scopus 로고    scopus 로고
    • Rat liver myofibroblasts and hepatic stellate cells differ in CD95-mediated apoptosis and response to TNF-alpha
    • Saile B, Matthes N, Neubauer K, et al. Rat liver myofibroblasts and hepatic stellate cells differ in CD95-mediated apoptosis and response to TNF-alpha. Am J Physiol Gastrointest Liver Physiol 2002;283: G435-G444.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Saile, B.1    Matthes, N.2    Neubauer, K.3
  • 26
    • 0026019613 scopus 로고
    • Purification and partial characterisation of the major cell-associated heparan sulphate proteoglycan of rat liver
    • Lyon M, Gallagher JT. Purification and partial characterisation of the major cell-associated heparan sulphate proteoglycan of rat liver. Biochem J 1991; 273:415-422.
    • (1991) Biochem J , vol.273 , pp. 415-422
    • Lyon, M.1    Gallagher, J.T.2
  • 27
    • 0023758772 scopus 로고
    • Monoclonal antibodies to heparan sulfate proteoglycan: Development and application to the study of normal tissue and pathologic human kidney biopsies
    • Kemeny E, Fillit HM, Damle S, et al. Monoclonal antibodies to heparan sulfate proteoglycan: development and application to the study of normal tissue and pathologic human kidney biopsies. Connect Tissue Res 1988;18:9-25.
    • (1988) Connect Tissue Res , vol.18 , pp. 9-25
    • Kemeny, E.1    Fillit, H.M.2    Damle, S.3
  • 28
    • 0033491136 scopus 로고    scopus 로고
    • Syndecan-1 expression is induced in the stroma of infiltrating breast carcinoma
    • Stanley MJ, Stanley MW, Sanderson RD, et al. Syndecan-1 expression is induced in the stroma of infiltrating breast carcinoma. Am J Clin Pathol 1999;112:377-383.
    • (1999) Am J Clin Pathol , vol.112 , pp. 377-383
    • Stanley, M.J.1    Stanley, M.W.2    Sanderson, R.D.3
  • 29
    • 0034079579 scopus 로고    scopus 로고
    • Syndecan-1 expression is decreased with increasing aggressiveness of basal cell carcinoma
    • Bayer-Garner IB, Dilday B, Sanderson RD, et al. Syndecan-1 expression is decreased with increasing aggressiveness of basal cell carcinoma. Am J Dermatopathol 2000;22:119-122.
    • (2000) Am J Dermatopathol , vol.22 , pp. 119-122
    • Bayer-Garner, I.B.1    Dilday, B.2    Sanderson, R.D.3
  • 30
    • 0035915759 scopus 로고    scopus 로고
    • Epithelial and stromal syndecan-1 expression as predictor of outcome in patients with gastric cancer
    • Wiksten JP, Lundin J, Nordling S, et al. Epithelial and stromal syndecan-1 expression as predictor of outcome in patients with gastric cancer. Int J Cancer 2001; 95:1-6.
    • (2001) Int J Cancer , vol.95 , pp. 1-6
    • Wiksten, J.P.1    Lundin, J.2    Nordling, S.3
  • 31
    • 10744228952 scopus 로고    scopus 로고
    • Syndecan-1 expression in thyroid carcinoma: Stromal expression followed by epithelial expression is significantly correlated with dedifferentiation
    • Ito Y, Yoshida H, Nakano K, et al. Syndecan-1 expression in thyroid carcinoma: stromal expression followed by epithelial expression is significantly correlated with dedifferentiation. Histopathology 2003;43:157-164.
    • (2003) Histopathology , vol.43 , pp. 157-164
    • Ito, Y.1    Yoshida, H.2    Nakano, K.3
  • 32
    • 0042890284 scopus 로고    scopus 로고
    • Induced expression of syndecan-1 in the stroma of head and neck squamous cell carcinoma
    • Mukunyadzi P, Liu K, Hanna EY, et al. Induced expression of syndecan-1 in the stroma of head and neck squamous cell carcinoma. Mod Pathol 2003; 16:796-801.
    • (2003) Mod Pathol , vol.16 , pp. 796-801
    • Mukunyadzi, P.1    Liu, K.2    Hanna, E.Y.3
  • 33
    • 0031851412 scopus 로고    scopus 로고
    • Heparan sulphate proteoglycan expression in human primary liver tumours
    • Roskams T, De Vos R, David G, et al. Heparan sulphate proteoglycan expression in human primary liver tumours. J Pathol 1998;185:290-297.
    • (1998) J Pathol , vol.185 , pp. 290-297
    • Roskams, T.1    De Vos, R.2    David, G.3
  • 34
    • 0029057388 scopus 로고
    • Identification of a novel alternatively spliced agrin mRNA that is preferentially expressed in non-neuronal cells
    • Tsen G, Napier A, Halfter W, et al. Identification of a novel alternatively spliced agrin mRNA that is preferentially expressed in non-neuronal cells. J Biol Chem 1995;270:15934-15937.
    • (1995) J Biol Chem , vol.270 , pp. 15934-15937
    • Tsen, G.1    Napier, A.2    Halfter, W.3
  • 35
    • 0033121275 scopus 로고    scopus 로고
    • The role of alphav integrins during angiogenesis: Insights into potential mechanisms of action and clinical development
    • Eliceiri BP, Cheresh DA. The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development. J Clin Invest 1999;103:1227-1230.
    • (1999) J Clin Invest , vol.103 , pp. 1227-1230
    • Eliceiri, B.P.1    Cheresh, D.A.2
  • 36
    • 2442488748 scopus 로고    scopus 로고
    • CNTO 95, a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo
    • Trikha M, Zhou Z, Nemeth JA, et al. CNTO 95, a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo. Int J Cancer 2004;110:326-335.
    • (2004) Int J Cancer , vol.110 , pp. 326-335
    • Trikha, M.1    Zhou, Z.2    Nemeth, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.