Na +/Ca 2+ exchanger-1 protects against systolic failure in the Akita ins2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 303, Issue 3, 2012, Pages 353-367

  LaRocca, Thomas J ^a   Fabris, Frank ^a   Chen, Jiqiu ^a   Benhayon, Daniel ^a   Zhang, Shihong ^a   McCollum, LaTronya ^a   Schecter, Alison D ^a   Cheung, Joseph Y ^b   Sobie, Eric A ^a   Hajjar, Roger J ^a   Lebeche, Djamel ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Action potential; Calcium cycling; Systolic function

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CALCIUM EXCHANGE PROTEIN 1; UNCLASSIFIED DRUG; CALCIUM; CXCL12 PROTEIN, MOUSE; CXCR4 PROTEIN, MOUSE; CXCR4 PROTEIN, RAT; INS2 PROTEIN, MOUSE; INSULIN; SODIUM CALCIUM EXCHANGER 1; SODIUM-CALCIUM EXCHANGER 1; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DIASTOLIC DYSFUNCTION; ECHOCARDIOGRAPHY; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE POTENTIAL; HEART PROTECTION; HEMODYNAMICS; IN VIVO STUDY; INFLAMMATORY INFILTRATE; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEM CELL; SYSTOLIC DYSFUNCTION; UPREGULATION; ACTION POTENTIAL; ANIMAL; CELL CULTURE; DIASTOLE; DISEASE MODEL; ECHOGRAPHY; GENE SILENCING; GENETICS; HEART LEFT VENTRICLE FUNCTION; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; RAT; SPRAGUE DAWLEY RAT; SYSTOLE;

ACTION POTENTIALS; ANIMALS; CALCIUM; CELLS, CULTURED; CHEMOKINE CXCL12; DIABETES MELLITUS, TYPE 1; DIABETIC CARDIOMYOPATHIES; DIASTOLE; DISEASE MODELS, ANIMAL; GENE KNOCKDOWN TECHNIQUES; HEMODYNAMICS; INSULIN; MALE; MICE; MYOCYTES, CARDIAC; NF-KAPPA B; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; SODIUM-CALCIUM EXCHANGER; SYSTOLE; UP-REGULATION; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

EID: 84864572907     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01198.2011     Document Type: Article

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