Targeted deletion of nuclear factor κB p50 enhances cardiac remodeling and dysfunction following myocardial infarction

Circulation Research

Volumn 104, Issue 5, 2009, Pages 699-706

  Timmers, Leo ^a   Van Keulen, J Karlijn ^a,b   Hoefer, Imo E ^a   Meijs, Matthijs F L ^a   Van Middelaar, Ben ^a   Den Ouden, Krista ^a   Van Echteld, Cees J A ^a   Pasterkamp, Gerard ^a   De Kleijn, Dominique P V ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

Ischemic heart disease; Myocardial infarction; NF B; Remodeling; Wound healing

Indexed keywords

COLLAGEN; GELATINASE; INTERLEUKIN 6; NUCLEAR FACTOR KAPPA B P50 SUBUNIT; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; AUTACOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE DELETION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTOLIC DYSFUNCTION; ANIMAL; CARDIOMEGALY; CELL CULTURE; DISEASE MODEL; DRUG EFFECT; FIBROSIS; GENETICS; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART STROKE VOLUME; HUMAN; INFLAMMATION; METABOLISM; MOUSE MUTANT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; TIME; WOUND HEALING;

ANIMALS; CARDIOMEGALY; CELLS, CULTURED; COLLAGEN; DISEASE MODELS, ANIMAL; FIBROSIS; GENE DELETION; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MAGNETIC RESONANCE IMAGING; MICE; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; MYOCARDIUM; NF-KAPPA B P50 SUBUNIT; STROKE VOLUME; TIME FACTORS; TRANSCRIPTION FACTOR RELA; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING; WOUND HEALING;

EID: 63649110166     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.189746     Document Type: Article

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