Allosteric activation of Na+-Ca2+ exchange by L-type Ca2+ current augments the trigger flux for SR Ca2+ release in ventricular myocytes

Biophysical Journal

Volumn 94, Issue 7, 2008, Pages

  Sobie, Eric A ^a   Cannell, Mark B ^b   Bridge, John H B ^c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHANNEL L TYPE; SODIUM; SODIUM CALCIUM EXCHANGE PROTEIN;

ANIMAL; CALCIUM SIGNALING; CELL CULTURE; CHANNEL GATING; CYTOLOGY; HEART MUSCLE CELL; HEART VENTRICLE; LETTER; METABOLISM; PHYSIOLOGY; RABBIT; SARCOPLASMIC RETICULUM;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELLS, CULTURED; HEART VENTRICLES; ION CHANNEL GATING; MYOCYTES, CARDIAC; RABBITS; SARCOPLASMIC RETICULUM; SODIUM; SODIUM-CALCIUM EXCHANGER;

EID: 41649092522     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1529/biophysj.107.127878     Document Type: Article

References (14)

1. Cheng, H., W. J. Lederer, and M. B. Cannell. 1993. Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science. 262:740-744.
2. Cannell, M. B., H. Cheng, and W. J. Lederer. 1995. The control of calcium release in heart muscle. Science. 268:1045-1049.
3. Na-Ca in cardiac myocytes. Science. 248:376-378.
4. Bouchard, R. A., R. B. Clark, and W. R. Giles. 1993. Role of sodium-calcium exchange in activation of contraction in rat ventricle. J. Physiol. 472:391-413.
5. 2+ exchange. Science. 255:850-853.
6. 2+ exchange. Circ. Res. 81:1034-1044.
7. Litwin, S. E., J. Li, and J. H. Bridge. 1998. Na-Ca exchange and the trigger for sarcoplasmic reticulum Ca release: studies in adult rabbit ventricular myocytes. Biophys. J. 75:359-371.
8. i transients in mouse ventricular myocytes. Biophys. J. 80:1230-1237.
9. 2+ exchange in activation of excitation- contraction coupling in rat ventricular myocytes. J. Physiol. 493:529-542.
10. Shannon, T. R., K. S. Ginsburg, and D. M. Bers. 2000. Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration. Biophys. J. 78:334-343.
11. Hilgemann, D. W., A. Collins, and S. Matsuoka. 1992. Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP. J. Gen. Physiol. 100:933-961.
12. Miura, Y., and J. Kimura. 1989. Sodium-calcium exchange current. Dependence on internal Ca and Na and competitive binding of external Na and Ca. J. Gen. Physiol. 93:1129-1145.
13. Haworth, R. A., and A. B. Goknur. 1991. Control of the Na-Ca exchanger in isolated heart-cells. 2. Beat-dependent activation in normal-cells by intracellular calcium. Circ. Res. 69:1514-1524.
14. 2+ exchanger in normal and failing heart. J. Physiol. 567:493-504.