메뉴 건너뛰기




Volumn 56, Issue 5, 2010, Pages 548-559

β2-adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4

Author keywords

beta adrenergic receptors; chemokines; dimerization; g protein coupled receptors; heart failure

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CHEMOKINE RECEPTOR CXCR4; GUANINE NUCLEOTIDE BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1;

EID: 78650172422     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e3181f713fe     Document Type: Article
Times cited : (65)

References (47)
  • 1
    • 14944338800 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells
    • Guyon A, Rovere C, Cervantes A, et al. Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells. J Neurochem. 2005;93:963-973.
    • (2005) J Neurochem , vol.93 , pp. 963-973
    • Guyon, A.1    Rovere, C.2    Cervantes, A.3
  • 2
    • 68949122522 scopus 로고    scopus 로고
    • Hepatic stellate cells express functional cxcr4: Role in stromal cell-derived factor-1alpha-mediated stellate cell activation
    • Hong F, Tuyama A, Lee TF, et al. Hepatic stellate cells express functional cxcr4: Role in stromal cell-derived factor-1alpha-mediated stellate cell activation. Hepatology. 2009;49:2055-2067.
    • (2009) Hepatology , vol.49 , pp. 2055-2067
    • Hong, F.1    Tuyama, A.2    Lee, T.F.3
  • 3
    • 36849017633 scopus 로고    scopus 로고
    • Bile salt-dependent lipase interacts with platelet cxcr4 and modulates thrombus formation in mice and humans
    • Panicot-Dubois L, Thomas GM, Furie BC, et al. Bile salt-dependent lipase interacts with platelet cxcr4 and modulates thrombus formation in mice and humans. J Clin Invest. 2007;117:3708-3719.
    • (2007) J Clin Invest , vol.117 , pp. 3708-3719
    • Panicot-Dubois, L.1    Thomas, G.M.2    Furie, B.C.3
  • 4
    • 0242637601 scopus 로고    scopus 로고
    • What is the role of beta-adrenergic signaling in heart failure?
    • Lohse MJ, Engelhardt S, Eschenhagen T. What is the role of beta-adrenergic signaling in heart failure? Circ Res. 2003;93:896-906.
    • (2003) Circ Res , vol.93 , pp. 896-906
    • Lohse, M.J.1    Engelhardt, S.2    Eschenhagen, T.3
  • 5
    • 44049090880 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction
    • Saxena A, Fish JE, White MD, et al. Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction. Circulation. 2008;117:2224-2231.
    • (2008) Circulation , vol.117 , pp. 2224-2231
    • Saxena, A.1    Fish, J.E.2    White, M.D.3
  • 6
    • 34548174756 scopus 로고    scopus 로고
    • Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: Role of the cardiac stromal cell derived factor-1 alpha cxcr4 axis
    • Hu X, Dai S, Wu WJ, et al. Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha cxcr4 axis. Circulation. 2007; 116:654-663.
    • (2007) Circulation , vol.116 , pp. 654-663
    • Hu, X.1    Dai, S.2    Wu, W.J.3
  • 7
    • 0041327804 scopus 로고    scopus 로고
    • Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy
    • Askari AT, Unzek S, Popovic ZB, et al. Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy. Lancet. 2003;362:697-703.
    • (2003) Lancet , vol.362 , pp. 697-703
    • Askari, A.T.1    Unzek, S.2    Popovic, Z.B.3
  • 8
    • 77950574556 scopus 로고    scopus 로고
    • Effects of cxcr4 gene transfer on cardiac function after ischemia-reperfusion injury
    • Chen J, Chemaly E, Liang L, et al. Effects of cxcr4 gene transfer on cardiac function after ischemia-reperfusion injury. Am J Pathol. 2010; 176:1705-1715.
    • (2010) Am J Pathol , vol.176 , pp. 1705-1715
    • Chen, J.1    Chemaly, E.2    Liang, L.3
  • 9
    • 77954641959 scopus 로고    scopus 로고
    • Cxcr4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction
    • Jujo K, Hamada H, Iwakura A, et al. Cxcr4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction. Proc Natl Acad Sci USA. 2010;107: 11008-11013.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11008-11013
    • Jujo, K.1    Hamada, H.2    Iwakura, A.3
  • 10
    • 77956170434 scopus 로고    scopus 로고
    • Chronic amd3100 antagonism of sdf-1alpha-cxcr4 exacerbates cardiac dysfunction and remodeling after myocardial infarction
    • Dai S, Yuan F, Mu J, et al. Chronic amd3100 antagonism of sdf-1alpha-cxcr4 exacerbates cardiac dysfunction and remodeling after myocardial infarction. J Mol Cell Cardiol. 2010;49:587-597.
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 587-597
    • Dai, S.1    Yuan, F.2    Mu, J.3
  • 11
    • 77957065896 scopus 로고    scopus 로고
    • Role of cardiac myocyte cxcr4 expression in development and left ventricular remodeling after acute myocardial infarction
    • Agarwal U, Ghalayini W, Dong F, et al. Role of cardiac myocyte cxcr4 expression in development and left ventricular remodeling after acute myocardial infarction. Circ Res. 2010;107:667-676.
    • (2010) Circ Res , vol.107 , pp. 667-676
    • Agarwal, U.1    Ghalayini, W.2    Dong, F.3
  • 12
    • 0034223628 scopus 로고    scopus 로고
    • Sdf-1alpha-mediated modulation of synaptic transmission in rat cerebellum
    • Limatola C, Giovannelli A, Maggi L, et al. Sdf-1alpha-mediated modulation of synaptic transmission in rat cerebellum. Eur J Neurosci. 2000;12:2497-2504.
    • (2000) Eur J Neurosci , vol.12 , pp. 2497-2504
    • Limatola, C.1    Giovannelli, A.2    Maggi, L.3
  • 13
    • 34547415525 scopus 로고    scopus 로고
    • The chemokine stromal cell-derived factor-1/cxcl12 activates the nigrostriatal dopamine system
    • Skrzydelski D, Guyon A, Dauge V, et al. The chemokine stromal cell-derived factor-1/cxcl12 activates the nigrostriatal dopamine system. J Neurochem. 2007;102:1175-1183.
    • (2007) J Neurochem , vol.102 , pp. 1175-1183
    • Skrzydelski, D.1    Guyon, A.2    Dauge, V.3
  • 14
    • 34248172543 scopus 로고    scopus 로고
    • Multiple actions of the chemokine stromal cell-derived factor-1alpha on neuronal activity
    • Guyon A, Nahon JL. Multiple actions of the chemokine stromal cell-derived factor-1alpha on neuronal activity. J Mol Endocrinol. 2007;38: 365-376.
    • (2007) J Mol Endocrinol , vol.38 , pp. 365-376
    • Guyon, A.1    Nahon, J.L.2
  • 15
    • 33750352306 scopus 로고    scopus 로고
    • Cxcr4 modulates contractility in adult cardiac myocytes
    • Pyo RT, Sui J, Dhume A, et al. Cxcr4 modulates contractility in adult cardiac myocytes. J Mol Cell Cardiol. 2006;41:834-844.
    • (2006) J Mol Cell Cardiol , vol.41 , pp. 834-844
    • Pyo, R.T.1    Sui, J.2    Dhume, A.3
  • 16
    • 0022980843 scopus 로고
    • Beta 1-and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: Coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure
    • Bristow MR, Ginsburg R, Umans V, et al. Beta 1-and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure. Circ Res. 1986;59:297-309.
    • (1986) Circ Res , vol.59 , pp. 297-309
    • Bristow, M.R.1    Ginsburg, R.2    Umans, V.3
  • 17
    • 0034916343 scopus 로고    scopus 로고
    • Chemokines in myocardial failure\pathogenic importance and potential therapeutic targets
    • Aukrust P, Damas JK, Gullestad L, et al. Chemokines in myocardial failure\pathogenic importance and potential therapeutic targets. Clin Exp Immunol. 2001;124:343-345.
    • (2001) Clin Exp Immunol , vol.124 , pp. 343-345
    • Aukrust, P.1    Damas, J.K.2    Gullestad, L.3
  • 18
    • 77955474568 scopus 로고    scopus 로고
    • Integrin-linked kinase is a central mediator in angiotensin II type 1-and chemokine receptor cxcr4 signaling in myocardial hypertrophy
    • Bettink SI, Werner C, Chen CH, et al. Integrin-linked kinase is a central mediator in angiotensin II type 1-and chemokine receptor cxcr4 signaling in myocardial hypertrophy. Biochem Biophys Res Commun. 2010;397: 208-213.
    • (2010) Biochem Biophys Res Commun , vol.397 , pp. 208-213
    • Bettink, S.I.1    Werner, C.2    Chen, C.H.3
  • 19
    • 24044453234 scopus 로고    scopus 로고
    • Mcp-1/ccl2 protects cardiac myocytes from hypoxia-induced apoptosis by a g(alphai)-independent pathway
    • Tarzami ST, Calderon TM, Deguzman A, et al. Mcp-1/ccl2 protects cardiac myocytes from hypoxia-induced apoptosis by a g(alphai)-independent pathway. Biochem Biophys Res Commun. 2005;335: 1008-1016.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 1008-1016
    • Tarzami, S.T.1    Calderon, T.M.2    Deguzman, A.3
  • 20
    • 0038024047 scopus 로고    scopus 로고
    • Expression of functional cxcr4 by muscle satellite cells and secretion of sdf-1 by muscle-derived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles
    • Ratajczak MZ, Majka M, Kucia M, et al. Expression of functional cxcr4 by muscle satellite cells and secretion of sdf-1 by muscle-derived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles. Stem Cells. 2003;21:363-371.
    • (2003) Stem Cells , vol.21 , pp. 363-371
    • Ratajczak, M.Z.1    Majka, M.2    Kucia, M.3
  • 21
    • 0032483419 scopus 로고    scopus 로고
    • The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane g-protein-coupled cxcr-4 receptor and activates multiple signal transduction pathways
    • Ganju RK, Brubaker SA, Meyer J, et al. The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane g-protein-coupled cxcr-4 receptor and activates multiple signal transduction pathways. J Biol Chem. 1998;273:23169-23175.
    • (1998) J Biol Chem , vol.273 , pp. 23169-23175
    • Ganju, R.K.1    Brubaker, S.A.2    Meyer, J.3
  • 22
    • 0031940489 scopus 로고    scopus 로고
    • Development of a fluorescent indicator for nitric oxide based on the fluorescein chromophore
    • Kojima H, Sakurai K, Kikuchi K, et al. Development of a fluorescent indicator for nitric oxide based on the fluorescein chromophore. Chem Pharm Bull (Tokyo). 1998;46:373-375.
    • (1998) Chem Pharm Bull (Tokyo) , vol.46 , pp. 373-375
    • Kojima, H.1    Sakurai, K.2    Kikuchi, K.3
  • 23
    • 34247115166 scopus 로고    scopus 로고
    • Conformation state-sensitive antibodies to g-protein-coupled receptors
    • Gupta A, Decaillot FM, Gomes I, et al. Conformation state-sensitive antibodies to g-protein-coupled receptors. J Biol Chem. 2007;282: 5116-5124.
    • (2007) J Biol Chem , vol.282 , pp. 5116-5124
    • Gupta, A.1    Decaillot, F.M.2    Gomes, I.3
  • 24
    • 0034023217 scopus 로고    scopus 로고
    • Induction of ig9 monocyte adhesion molecule expression in smooth muscle and endothelial cells after balloon arterial injury in cholesterol-fed rabbits
    • Calderon TM, Gertz SD, Sarembock IJ, et al. Induction of ig9 monocyte adhesion molecule expression in smooth muscle and endothelial cells after balloon arterial injury in cholesterol-fed rabbits. Arterioscler Thromb Vasc Biol. 2000;20:1293-1300.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1293-1300
    • Calderon, T.M.1    Gertz, S.D.2    Sarembock, I.J.3
  • 25
    • 33745085564 scopus 로고    scopus 로고
    • Mu opioid and cb1 cannabinoid receptor interactions: Reciprocal inhibition of receptor signaling and neurito-genesis
    • Rios C, Gomes I, Devi LA. Mu opioid and cb1 cannabinoid receptor interactions: Reciprocal inhibition of receptor signaling and neurito-genesis. Br J Pharmacol. 2006;148:387-395.
    • (2006) Br J Pharmacol , vol.148 , pp. 387-395
    • Rios, C.1    Gomes, I.2    Devi, L.A.3
  • 26
    • 44449087996 scopus 로고    scopus 로고
    • Monitoring protein-protein interactions in living cells by bioluminescence resonance energy transfer (BRET)
    • Chapter 5:Unit 5.23
    • Hamdan FF, Percherancier Y, Breton B, et al. Monitoring protein-protein interactions in living cells by bioluminescence resonance energy transfer (BRET). Curr Protoc Neurosci. 2006;Chapter 5:Unit 5.23.
    • (2006) Curr Protoc Neurosci
    • Hamdan, F.F.1    Percherancier, Y.2    Breton, B.3
  • 27
    • 0034724192 scopus 로고    scopus 로고
    • Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)
    • Angers S, Salahpour A, Joly E, et al. Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proc Natl Acad Sci USA. 2000;97:3684-3689.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3684-3689
    • Angers, S.1    Salahpour, A.2    Joly, E.3
  • 28
    • 0037605745 scopus 로고    scopus 로고
    • Opioid receptor oligomerization. Detection and functional characterization of interacting receptors
    • Gomes I, Filipovska J, Devi LA. Opioid receptor oligomerization. Detection and functional characterization of interacting receptors. Methods Mol Med. 2003;84:157-183.
    • (2003) Methods Mol Med , vol.84 , pp. 157-183
    • Gomes, I.1    Filipovska, J.2    Devi, L.A.3
  • 29
    • 0027339466 scopus 로고
    • Major differences in ca2+i response to anoxia between neonatal and adult rat ca1 neurons: Role of ca2+o and na+o
    • Friedman JE, Haddad GG. Major differences in ca2+i response to anoxia between neonatal and adult rat ca1 neurons: Role of ca2+o and na+o. J Neurosci. 1993;13:63-72.
    • (1993) J Neurosci , vol.13 , pp. 63-72
    • Friedman, J.E.1    Haddad, G.G.2
  • 30
    • 0036897624 scopus 로고    scopus 로고
    • Nitric oxide and myocardial function in heart failure: Friend or foe?
    • Cotton JM, Kearney MT, Shah AM. Nitric oxide and myocardial function in heart failure: friend or foe? Heart. 2002;88:564-566.
    • (2002) Heart , vol.88 , pp. 564-566
    • Cotton, J.M.1    Kearney, M.T.2    Shah, A.M.3
  • 31
    • 34548442113 scopus 로고    scopus 로고
    • Comparing the structure and dynamics of phospholamban pentamer in its unphosphorylated and pseudo-phosphor-ylated states
    • Oxenoid K, Rice AJ, Chou JJ. Comparing the structure and dynamics of phospholamban pentamer in its unphosphorylated and pseudo-phosphor-ylated states. Protein Sci. 2007;16:1977-1983.
    • (2007) Protein Sci , vol.16 , pp. 1977-1983
    • Oxenoid, K.1    Rice, A.J.2    Chou, J.J.3
  • 32
    • 0035726693 scopus 로고    scopus 로고
    • G-protein-coupled receptor dimerization: Modulation of receptor function
    • Rios CD, Jordan BA, Gomes I, et al. G-protein-coupled receptor dimerization: modulation of receptor function. Pharmacol Ther. 2001;92: 71-87.
    • (2001) Pharmacol Ther , vol.92 , pp. 71-87
    • Rios, C.D.1    Jordan, B.A.2    Gomes, I.3
  • 33
    • 37249047120 scopus 로고    scopus 로고
    • Basic concepts in g-protein-coupled receptor homo-and heterodimerization
    • Franco R, Casado V, Cortes A, et al. Basic concepts in g-protein-coupled receptor homo-and heterodimerization. Scientific World Journal. 2007;7: 48-57.
    • (2007) Scientific World Journal , vol.7 , pp. 48-57
    • Franco, R.1    Casado, V.2    Cortes, A.3
  • 34
    • 15444377047 scopus 로고    scopus 로고
    • Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in cxcr4 homo-and heterodimers
    • Percherancier Y, Berchiche YA, Slight I, et al. Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in cxcr4 homo-and heterodimers. J Biol Chem. 2005;280:9895-9903.
    • (2005) J Biol Chem , vol.280 , pp. 9895-9903
    • Percherancier, Y.1    Berchiche, Y.A.2    Slight, I.3
  • 35
    • 42249106416 scopus 로고    scopus 로고
    • Ligand stabilization of cxcr4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation
    • Pello OM, Martinez-Munoz L, Parrillas V, et al. Ligand stabilization of cxcr4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation. Eur J Immunol. 2008;38:537-549.
    • (2008) Eur J Immunol , vol.38 , pp. 537-549
    • Pello, O.M.1    Martinez-Munoz, L.2    Parrillas, V.3
  • 36
    • 36048947671 scopus 로고    scopus 로고
    • Trafficking of preassembled opioid mu-delta heterooligomer-gz signaling complexes to the plasma membrane: Coregulation by agonists
    • Hasbi A, Nguyen T, Fan T, et al. Trafficking of preassembled opioid mu-delta heterooligomer-gz signaling complexes to the plasma membrane: coregulation by agonists. Biochemistry. 2007;46:12997-13009.
    • (2007) Biochemistry , vol.46 , pp. 12997-13009
    • Hasbi, A.1    Nguyen, T.2    Fan, T.3
  • 37
    • 23344449115 scopus 로고    scopus 로고
    • Heterodimerization of beta1-and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility
    • Zhu WZ, Chakir K, Zhang S, et al. Heterodimerization of beta1-and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility. Circ Res. 2005;97:244-251.
    • (2005) Circ Res , vol.97 , pp. 244-251
    • Zhu, W.Z.1    Chakir, K.2    Zhang, S.3
  • 38
    • 0030613761 scopus 로고    scopus 로고
    • Switching of the coupling of the beta2-adrenergic receptor to different g proteins by protein kinase a
    • Daaka Y, Luttrell LM, Lefkowitz RJ. Switching of the coupling of the beta2-adrenergic receptor to different g proteins by protein kinase a. Nature. 1997;390:88-91.
    • (1997) Nature , vol.390 , pp. 88-91
    • Daaka, Y.1    Luttrell, L.M.2    Lefkowitz, R.J.3
  • 39
    • 70350521076 scopus 로고    scopus 로고
    • Akt increases sarcoplasmic reticulum ca2+ cycling by direct phosphorylation of phospholamban at thr17
    • Catalucci D, Latronico MV, Ceci M, et al. Akt increases sarcoplasmic reticulum ca2+ cycling by direct phosphorylation of phospholamban at thr17. J Biol Chem. 2009;284:28180-28187.
    • (2009) J Biol Chem , vol.284 , pp. 28180-28187
    • Catalucci, D.1    Latronico, M.V.2    Ceci, M.3
  • 40
    • 37349085478 scopus 로고    scopus 로고
    • Activation or inactivation of cardiac akt/mtor signaling diverges physiological from pathological hypertrophy
    • Kemi OJ, Ceci M, Wisloff U, et al. Activation or inactivation of cardiac akt/mtor signaling diverges physiological from pathological hypertrophy. J Cell Physiol. 2008;214:316-321.
    • (2008) J Cell Physiol , vol.214 , pp. 316-321
    • Kemi, O.J.1    Ceci, M.2    Wisloff, U.3
  • 41
    • 67650257490 scopus 로고    scopus 로고
    • Growth hormone-releasing hormone promotes survival of cardiac myocytes in vitro and protects against ischaemia-reperfusion injury in rat heart
    • Granata R, Trovato L, Gallo MP, et al. Growth hormone-releasing hormone promotes survival of cardiac myocytes in vitro and protects against ischaemia-reperfusion injury in rat heart. Cardiovasc Res. 2009; 83:303-312.
    • (2009) Cardiovasc Res , vol.83 , pp. 303-312
    • Granata, R.1    Trovato, L.2    Gallo, M.P.3
  • 42
    • 5644260063 scopus 로고    scopus 로고
    • The cardiac beta2-adrenergic signalling a new role for the cpla2
    • Pavoine C, Defer N. The cardiac beta2-adrenergic signalling a new role for the cpla2. Cell Signal. 2005;17:141-152.
    • (2005) Cell Signal , vol.17 , pp. 141-152
    • Pavoine, C.1    Defer, N.2
  • 43
    • 0032507962 scopus 로고    scopus 로고
    • Function of the chemokine receptor cxcr4 in haematopoiesis and in cerebellar development
    • Zou YR, Kottmann AH, Kuroda M, et al. Function of the chemokine receptor cxcr4 in haematopoiesis and in cerebellar development. Nature. 1998;393:595-599.
    • (1998) Nature , vol.393 , pp. 595-599
    • Zou, Y.R.1    Kottmann, A.H.2    Kuroda, M.3
  • 44
    • 0036859163 scopus 로고    scopus 로고
    • The beta-adrenergic receptors
    • Wallukat G. The beta-adrenergic receptors. Herz. 2002;27:683-690.
    • (2002) Herz , vol.27 , pp. 683-690
    • Wallukat, G.1
  • 45
    • 0036749973 scopus 로고    scopus 로고
    • Beta-adrenergic receptor signaling pathways mediating cell survival in cardiomyocytes: A role for pkc epsilon inhibition?
    • Crow MT. Beta-adrenergic receptor signaling pathways mediating cell survival in cardiomyocytes: a role for pkc epsilon inhibition? J Mol Cell Cardiol. 2002;34:1121-1125.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1121-1125
    • Crow, M.T.1
  • 46
    • 51849154376 scopus 로고    scopus 로고
    • Pro-apoptotic effects of anti-beta1-adrenergic receptor antibodies in cultured rat cardiomyocytes: Actions on endoplasmic reticulum and the prosurvival pi3k-akt pathway
    • Liang CS, Mao W, Liu J. Pro-apoptotic effects of anti-beta1-adrenergic receptor antibodies in cultured rat cardiomyocytes: actions on endoplasmic reticulum and the prosurvival pi3k-akt pathway. Autoimmunity. 2008;41:434-441.
    • (2008) Autoimmunity , vol.41 , pp. 434-441
    • Liang, C.S.1    Mao, W.2    Liu, J.3
  • 47
    • 58249130704 scopus 로고    scopus 로고
    • Prevalent role of akt and erk activation in cardioprotective effect of ca(2+) channel-and beta-adrenergic receptor blockers
    • Kovacs K, Hanto K, Bognar Z, et al. Prevalent role of akt and erk activation in cardioprotective effect of ca(2+) channel-and beta-adrenergic receptor blockers. Mol Cell Biochem. 2009;321:155-164.
    • (2009) Mol Cell Biochem , vol.321 , pp. 155-164
    • Kovacs, K.1    Hanto, K.2    Bognar, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.