메뉴 건너뛰기




Volumn 213, Issue 2, 2012, Pages 174-183

Protective role of metabolism by intestinal microflora in butyl paraben-induced toxicity in HepG2 cell cultures

Author keywords

Apoptosis; Butyl paraben; Cytotoxicity; Fecalase; Metabolism

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BUTYL PARABEN; CASPASE 3; CELL ENZYME; FECALASE; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 84864445187     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.07.004     Document Type: Article
Times cited : (16)

References (35)
  • 3
    • 84974710286 scopus 로고    scopus 로고
    • Final amended report on the safety assessment of methylparaben, ethylparaben, propylparaben, isopropylparaben, butylparaben, isobutylparaben, and benzylparaben as used in cosmetic products
    • Andersen F.A. Final amended report on the safety assessment of methylparaben, ethylparaben, propylparaben, isopropylparaben, butylparaben, isobutylparaben, and benzylparaben as used in cosmetic products. International Journal of Toxicology 2008, 27(Suppl. 4):1-82.
    • (2008) International Journal of Toxicology , vol.27 , Issue.SUPPL. 4 , pp. 1-82
    • Andersen, F.A.1
  • 7
    • 47549094487 scopus 로고    scopus 로고
    • Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks
    • Darbre P.D., Harvey P.W. Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks. Journal of Applied Toxicology 2008, 28:561-578.
    • (2008) Journal of Applied Toxicology , vol.28 , pp. 561-578
    • Darbre, P.D.1    Harvey, P.W.2
  • 8
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., Greenberg M.E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997, 91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 9
    • 0014176737 scopus 로고
    • Studies of intestinal microflora. I. Effects of diet, age, and periodic sampling on numbers of fecal microorganisms in man
    • Gorbach S.L., Nahas L., Lerner P.I., Weinstein L. Studies of intestinal microflora. I. Effects of diet, age, and periodic sampling on numbers of fecal microorganisms in man. Gastroenterology 1967, 53:845-855.
    • (1967) Gastroenterology , vol.53 , pp. 845-855
    • Gorbach, S.L.1    Nahas, L.2    Lerner, P.I.3    Weinstein, L.4
  • 12
    • 0034651781 scopus 로고    scopus 로고
    • Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction
    • Johnson M.R., Wang K., Smith J.B., Heslin M.J., Diasio R.B. Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction. Analytical Biochemistry 2000, 278:175-184.
    • (2000) Analytical Biochemistry , vol.278 , pp. 175-184
    • Johnson, M.R.1    Wang, K.2    Smith, J.B.3    Heslin, M.J.4    Diasio, R.B.5
  • 18
    • 77956179509 scopus 로고    scopus 로고
    • Molecular mechanisms of asbestos-induced lung epithelial cell apoptosis
    • Liu G., Beri R., Mueller A., Kamp D.W. Molecular mechanisms of asbestos-induced lung epithelial cell apoptosis. Chemico-Biological Interactions 2010, 188:309-318.
    • (2010) Chemico-Biological Interactions , vol.188 , pp. 309-318
    • Liu, G.1    Beri, R.2    Mueller, A.3    Kamp, D.W.4
  • 19
    • 56549120655 scopus 로고    scopus 로고
    • Determination of parabens in environmental solid samples by ultrasonic-assisted extraction and liquid chromatography with triple quadrupole mass spectrometry
    • Nunez L., Tadeo J.L., Garcia-Valcarcel A.I., Turiel E. Determination of parabens in environmental solid samples by ultrasonic-assisted extraction and liquid chromatography with triple quadrupole mass spectrometry. Journal of Chromatography A 2008, 1214:178-182.
    • (2008) Journal of Chromatography A , vol.1214 , pp. 178-182
    • Nunez, L.1    Tadeo, J.L.2    Garcia-Valcarcel, A.I.3    Turiel, E.4
  • 20
    • 58549115670 scopus 로고    scopus 로고
    • HY251, a novel cell cycle inhibitor isolated from Aralia continentalis, induces G1 phase arrest via p53-dependent pathway in HeLa cells
    • Oh H.L., Lim H., Cho Y.H., Koh H.C., Kim H., Lim Y., Lee C.H. HY251, a novel cell cycle inhibitor isolated from Aralia continentalis, induces G1 phase arrest via p53-dependent pathway in HeLa cells. Bioorganic and Medicinal Chemistry Letters 2009, 19:959-961.
    • (2009) Bioorganic and Medicinal Chemistry Letters , vol.19 , pp. 959-961
    • Oh, H.L.1    Lim, H.2    Cho, Y.H.3    Koh, H.C.4    Kim, H.5    Lim, Y.6    Lee, C.H.7
  • 21
    • 0036210730 scopus 로고    scopus 로고
    • Effects of butylparaben on the male reproductive system in rats
    • Oishi S. Effects of butylparaben on the male reproductive system in rats. Toxicology and Industrial Health 2001, 17:31-39.
    • (2001) Toxicology and Industrial Health , vol.17 , pp. 31-39
    • Oishi, S.1
  • 22
    • 0023680667 scopus 로고
    • Interactions of the gut microflora and the host in toxicology
    • Rowland I.R. Interactions of the gut microflora and the host in toxicology. Toxicology and Pathology 1988, 16:147-153.
    • (1988) Toxicology and Pathology , vol.16 , pp. 147-153
    • Rowland, I.R.1
  • 24
  • 26
    • 48549092932 scopus 로고    scopus 로고
    • Molecular profile of the BCL2 family of the apoptosis related genes in breast cancer cells after treatment with cytotoxic/cytostatic drugs
    • Thomadaki H., Scorilas A. Molecular profile of the BCL2 family of the apoptosis related genes in breast cancer cells after treatment with cytotoxic/cytostatic drugs. Connective Tissue Research 2008, 49:261-264.
    • (2008) Connective Tissue Research , vol.49 , pp. 261-264
    • Thomadaki, H.1    Scorilas, A.2
  • 28
    • 77953236227 scopus 로고    scopus 로고
    • Anti-pruritic effect of baicalin and its metabolites, baicalein and oroxylin A, in mice
    • Trinh H.T., Joh E.H., Kwak H.Y., Baek N.I., Kim D.H. Anti-pruritic effect of baicalin and its metabolites, baicalein and oroxylin A, in mice. Acta Pharmacologica Sinica 2010, 31:718-724.
    • (2010) Acta Pharmacologica Sinica , vol.31 , pp. 718-724
    • Trinh, H.T.1    Joh, E.H.2    Kwak, H.Y.3    Baek, N.I.4    Kim, D.H.5
  • 29
    • 0000828921 scopus 로고
    • Metabolism of drugs. XLVII. Metabolic fate of p-hydroxybenzoic acid and its derivatives in rabbit
    • Tsukamoto H., Terada S. Metabolism of drugs. XLVII. Metabolic fate of p-hydroxybenzoic acid and its derivatives in rabbit. Chemistry and Pharmaceutical Bulletin 1964, 12:765-769.
    • (1964) Chemistry and Pharmaceutical Bulletin , vol.12 , pp. 765-769
    • Tsukamoto, H.1    Terada, S.2
  • 32
    • 0034703742 scopus 로고    scopus 로고
    • P53: death star
    • Vousden K.H. p53: death star. Cell 2000, 103:691-694.
    • (2000) Cell , vol.103 , pp. 691-694
    • Vousden, K.H.1
  • 33
    • 0035195557 scopus 로고    scopus 로고
    • The evolution of diverse biological responses to DNA damage: insights from yeast and p53
    • Wahl G.M., Carr A.M. The evolution of diverse biological responses to DNA damage: insights from yeast and p53. Nature and Cell Biology 2001, 3:E277-E286.
    • (2001) Nature and Cell Biology , vol.3
    • Wahl, G.M.1    Carr, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.