Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in Aspergillus niger reveals a coordinated cellular response to counteract ER stress

BMC Genomics

Volumn 13, Issue 1, 2012, Pages

  Carvalho, Neuza D S P ^a,b   Jørgensen, Thomas R ^a,b,d   Arentshorst, Mark ^a   Nitsche, Benjamin M ^a,e   van den Hondel, Cees A M J J ^a,b   Archer, David B ^c   Ram, Arthur F J ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b KLUYVER CENTRE FOR GENOMICS OF INDUSTRIAL FERMENTATION   (Netherlands)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d NOVO NORDISK A S   (Denmark)

^e TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Aspergillus niger; HacA; Protein secretion; RESS; Secretion stress; Unfolded protein response; XBP1

Indexed keywords

AMYR TRANSCRIPTION FACTOR; HACA TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; FUNGAL PROTEIN;

ARTICLE; ASPERGILLUS NIGER; BATCH REACTOR; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENDOPLASMIC RETICULUM STRESS; EXOCYTOSIS; FUNGAL GENE; FUNGAL GENOME; FUNGAL STRAIN; GENE EXPRESSION; HACA GENE; HETEROLOGOUS EXPRESSION; INTRACELLULAR TRANSPORT; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; PROTEIN TRANSPORT; REGULON; SECRETION (PROCESS); TRANSCRIPTOMICS; TRANSGENIC ORGANISM; UNFOLDED PROTEIN RESPONSE; UPREGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY;

ASPERGILLUS NIGER; EUKARYOTA;

ASPERGILLUS NIGER; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; ENDOPLASMIC RETICULUM STRESS; FUNGAL PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; UNFOLDED PROTEIN RESPONSE;

EID: 84864366831     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-13-350     Document Type: Article

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