Impaired cutinase secretion in Saccharomyces cerevisiae induces irregular endoplasmic reticulum (ER) membrane proliferation, oxidative stress, and ER-associated degradation

Applied and Environmental Microbiology

Volumn 68, Issue 5, 2002, Pages 2155-2160

  Sagt, C M J ^a   Muller W H ^a   Van der Heide, L ^a   Boonstra, J ^a   Verkleij, A J ^a   Verrips, C T ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; CELLS; HYDROPHOBICITY; MORPHOLOGY;

OXIDATIVE STRESS;

ENZYMES;

CUTINASE;

FUNGUS;

ARTICLE; ENDOPLASMIC RETICULUM; ENZYME DEGRADATION; ENZYME RELEASE; ENZYME SYNTHESIS; FUNGUS GROWTH; HYDROPHOBICITY; MORPHOLOGY; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE;

CARBOXYLIC ESTER HYDROLASES; CYSTEINE ENDOPEPTIDASES; ENDOPLASMIC RETICULUM; HYDROPHOBICITY; MULTIENZYME COMPLEXES; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN DENATURATION; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE;

FUNGI; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0036249934     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.68.5.2155-2160.2002     Document Type: Article

References (33)

1. Stress resistance in Saccharomyces cerevisiae is strongly correlated with assembly of a novel type of multiubiquitin chain
2. The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct
3. Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway
4. Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor
5. The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane
6. Membrane topology and function for Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation
7. A regulatory link between ER-associated protein degradation and the unfolded-protein response
8. Proteolysis in cultured liver epithelial cells during oxidative stress
9. ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway
10. Ubiquitin-dependent protein degradation
11. High-pressure freezing of cell suspensions in celllulose capillary tubes
12. Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis
13. A proteolytic pathway that recognizes ubiquitin as a degradation signal
14. Heterologous gene expression in Saccharomyces cerevisiae
15. Cutinases from fungi and pollen
16. Alzheimer's Abeta1-40 pepticle modulates lipid synthesis in neuronal cultures and intact rat fetal brain under normoxic and oxidative stress conditions
17. Determination of carbonyl content in oxidatively modified proteins
18. Fusarium solani cutinase is a lipolytic enzyme with a catalytic serine accessible to solvent
19. The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control
20. Rapid degradation of auxin/indoleacetic acid proteins requires conserved amino acids of domain II and is proteasome dependent
21. Impaired secretion of a hydrophobic cutinase by Saccharomyces cerevisiae correlates with an increased association with immunoglobulin heavy-chain binding protein (BiP)
22. Introduction of an N-glycosylation site increases secretion of heterologous proteins in yeasts
23. Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins
24. Oxidative modification of fibrinogen inhibits thrombin-catalyzed clot formation
25. The Cdc25 protein of Saccharomyces cerevisiae is required for normal glucose transport
26. Cryo-fixation and cryo-substitution for routine work in transmission electron microscopy
27. Genetic analysis of ubiquitin-dependent protein degradation
28. A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum
29. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
30. Accumulation of misfolded protein aggregates leads to the formation of Russell body-like dilated endoplasmic reticulum in yeast
31. Activation of the Ras-cAMP signal pathway inhibits the proteasome- independent degradation of misfolded protein aggregates in the endoplasmic reticulum lumen
32. Construction and heterologous expression of a synthetic copy of the cutinase cDNA from Fusarium solani pisi
33. The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol