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Volumn 2, Issue 8, 2004, Pages

Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GCN4; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; DNA; DNA BINDING PROTEIN; GCN2 PROTEIN, S CEREVISIAE; GCN4 PROTEIN, S CEREVISIAE; HAC1 PROTEIN, S CEREVISIAE; OLIGONUCLEOTIDE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; REPRESSOR PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN;

EID: 19444370807     PISSN: 15449173     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pbio.0020246     Document Type: Article
Times cited : (140)

References (63)
  • 1
    • 0032557677 scopus 로고    scopus 로고
    • Monitoring the Gcn4 protein-mediated response in the yeast Saccharomyces cerevisiae
    • Albrecht G, Mosch HU, Hoffmann B, Reusser U, Braus GH (1998) Monitoring the Gcn4 protein-mediated response in the yeast Saccharomyces cerevisiae. J Biol Chem 273: 12696-12702.
    • (1998) J Biol Chem , vol.273 , pp. 12696-12702
    • Albrecht, G.1    Mosch, H.U.2    Hoffmann, B.3    Reusser, U.4    Braus, G.H.5
  • 4
    • 0034730161 scopus 로고    scopus 로고
    • Building a dictionary for genomes: Identification of presumptive regulatory sites by statistical analysis
    • Bussemaker HJ, Li H, Siggia ED (2000a) Building a dictionary for genomes: Identification of presumptive regulatory sites by statistical analysis. Proc Natl Acad Sci U S A 97: 10096-10100.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 10096-10100
    • Bussemaker, H.J.1    Li, H.2    Siggia, E.D.3
  • 6
    • 0037011917 scopus 로고    scopus 로고
    • IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
    • Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, et al. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415: 92-96.
    • (2002) Nature , vol.415 , pp. 92-96
    • Calfon, M.1    Zeng, H.2    Urano, F.3    Till, J.H.4    Hubbard, S.R.5
  • 7
    • 0035940479 scopus 로고    scopus 로고
    • Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response
    • Carroll AS, Bishop AC, DeRisi JL, Shokat KM, O'Shea EK (2001) Chemical inhibition of the Pho85 cyclin-dependent kinase reveals a role in the environmental stress response. Proc Natl Acad Sci U S A 98: 12578-12583.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12578-12583
    • Carroll, A.S.1    Bishop, A.C.2    DeRisi, J.L.3    Shokat, K.M.4    O'Shea, E.K.5
  • 8
    • 0033637082 scopus 로고    scopus 로고
    • Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway
    • Casagrande R, Stern P, Diehn M, Shamu C, Osario M, et al. (2000) Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway. Mol Cell 5: 729-735.
    • (2000) Mol Cell , vol.5 , pp. 729-735
    • Casagrande, R.1    Stern, P.2    Diehn, M.3    Shamu, C.4    Osario, M.5
  • 9
    • 0023664018 scopus 로고
    • Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates
    • Cavener DR (1987) Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates. Nucleic Acids Res 15: 1353-1361.
    • (1987) Nucleic Acids Res , vol.15 , pp. 1353-1361
    • Cavener, D.R.1
  • 10
    • 0031282636 scopus 로고    scopus 로고
    • Translational attenuation mediated by an mRNA intron
    • Chapman RE, Walter P (1997) Translational attenuation mediated by an mRNA intron. Curr Biol 7: 850-859.
    • (1997) Curr Biol , vol.7 , pp. 850-859
    • Chapman, R.E.1    Walter, P.2
  • 11
    • 0037382865 scopus 로고    scopus 로고
    • Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2
    • Cherkasova VA, Hinnebusch AG (2003) Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2. Genes Dev 17: 859-872.
    • (2003) Genes Dev , vol.17 , pp. 859-872
    • Cherkasova, V.A.1    Hinnebusch, A.G.2
  • 12
    • 0038724989 scopus 로고    scopus 로고
    • Finding functional features in Saccharomyces genomes by phylogenetic footprinting
    • Cliften P, Sudarsanam P, Desikan A, Fulton L, Fulton B, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301: 71-76.
    • (2003) Science , vol.301 , pp. 71-76
    • Cliften, P.1    Sudarsanam, P.2    Desikan, A.3    Fulton, L.4    Fulton, B.5
  • 13
    • 0030297537 scopus 로고    scopus 로고
    • A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response
    • Cox JS, Walter P (1996) A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell 87: 391-404.
    • (1996) Cell , vol.87 , pp. 391-404
    • Cox, J.S.1    Walter, P.2
  • 14
    • 0027324844 scopus 로고
    • Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
    • Cox JS, Shamu CE, Walter P (1993) Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 73: 1197-1206.
    • (1993) Cell , vol.73 , pp. 1197-1206
    • Cox, J.S.1    Shamu, C.E.2    Walter, P.3
  • 15
    • 1642494891 scopus 로고    scopus 로고
    • Monomeric and dimeric bZIP transcription factor GCN4 bind at the same rate to their target DNA site
    • Cranz S, Berger C, Baici A, Jelesarov I, Bosshard HR (2004) Monomeric and dimeric bZIP transcription factor GCN4 bind at the same rate to their target DNA site. Biochemistry 43: 718-727.
    • (2004) Biochemistry , vol.43 , pp. 718-727
    • Cranz, S.1    Berger, C.2    Baici, A.3    Jelesarov, I.4    Bosshard, H.R.5
  • 16
    • 0027324505 scopus 로고
    • Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast
    • Dever TE, Chen JJ, Barber GN, Cigan AM, Feng L, et al. (1993) Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast. Proc Natl Acad Sci U S A 90: 4616-4620.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 4616-4620
    • Dever, T.E.1    Chen, J.J.2    Barber, G.N.3    Cigan, A.M.4    Feng, L.5
  • 17
    • 0028224923 scopus 로고
    • Genetic and biochemical evidence for yeast GCN2 protein kinase polymerization
    • Diallinas G, Thireos G (1994) Genetic and biochemical evidence for yeast GCN2 protein kinase polymerization. Gene 143: 21-27.
    • (1994) Gene , vol.143 , pp. 21-27
    • Diallinas, G.1    Thireos, G.2
  • 18
    • 0033780610 scopus 로고    scopus 로고
    • A regulatory link between ER-associated protein degradation and the unfolded-protein response
    • Friedlander R, Jarosch E, Urban J, Volkwein C, Sommer T (2000) A regulatory link between ER-associated protein degradation and the unfolded-protein response. Nat Cell Biol 2: 379-384.
    • (2000) Nat Cell Biol , vol.2 , pp. 379-384
    • Friedlander, R.1    Jarosch, E.2    Urban, J.3    Volkwein, C.4    Sommer, T.5
  • 19
    • 0020739930 scopus 로고
    • Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site
    • Guarente L, Mason T (1983) Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site. Cell 32: 1279-1286.
    • (1983) Cell , vol.32 , pp. 1279-1286
    • Guarente, L.1    Mason, T.2
  • 21
    • 0033590451 scopus 로고    scopus 로고
    • Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
    • Harding HP, Zhang Y, Ron D (1999) Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397: 271-274.
    • (1999) Nature , vol.397 , pp. 271-274
    • Harding, H.P.1    Zhang, Y.2    Ron, D.3
  • 22
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, et al. (2000a) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6: 1099-1108.
    • (2000) Mol Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5
  • 23
    • 0033634641 scopus 로고    scopus 로고
    • Perk is essential for translational regulation and cell survival during the unfolded protein response
    • Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D (2000b) Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 5: 897-904.
    • (2000) Mol Cell , vol.5 , pp. 897-904
    • Harding, H.P.1    Zhang, Y.2    Bertolotti, A.3    Zeng, H.4    Ron, D.5
  • 24
    • 0037353039 scopus 로고    scopus 로고
    • An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
    • Harding HP, Zhang Y, Zeng H, Novoa I, Lu PD, et al. (2003) An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 11: 619-633.
    • (2003) Mol Cell , vol.11 , pp. 619-633
    • Harding, H.P.1    Zhang, Y.2    Zeng, H.3    Novoa, I.4    Lu, P.D.5
  • 25
    • 0032693671 scopus 로고    scopus 로고
    • Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
    • Haze K, Yoshida H, Yanagi H, Yura T, Mori K (1999) Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol Biol Cell 10: 3787-3799.
    • (1999) Mol Biol Cell , vol.10 , pp. 3787-3799
    • Haze, K.1    Yoshida, H.2    Yanagi, H.3    Yura, T.4    Mori, K.5
  • 26
    • 0032826179 scopus 로고    scopus 로고
    • Identifying DNA and protein patterns with statistically significant alignments of multiple sequences
    • Hertz GZ, Stormo GD (1999) Identifying DNA and protein patterns with statistically significant alignments of multiple sequences. Bioinformatics 15: 563-577.
    • (1999) Bioinformatics , vol.15 , pp. 563-577
    • Hertz, G.Z.1    Stormo, G.D.2
  • 27
    • 0027490295 scopus 로고
    • Gene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2
    • Hinnebusch AG (1993) Gene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2. Mol Microbiol 10: 215-223.
    • (1993) Mol Microbiol , vol.10 , pp. 215-223
    • Hinnebusch, A.G.1
  • 28
    • 0030803256 scopus 로고    scopus 로고
    • Translational regulation of yeast GCN4: A window on factors that control initiator-trna binding to the ribosome
    • Hinnebusch AG (1997) Translational regulation of yeast GCN4: A window on factors that control initiator-trna binding to the ribosome. J Biol Chem 272: 21661-21664.
    • (1997) J Biol Chem , vol.272 , pp. 21661-21664
    • Hinnebusch, A.G.1
  • 29
    • 0034732899 scopus 로고    scopus 로고
    • GCN4 binds with high affinity to DNA sequences containing a single consensus half-site
    • Hollenbeck JJ, Oakley MG (2000) GCN4 binds with high affinity to DNA sequences containing a single consensus half-site. Biochemistry 39: 6380-6389.
    • (2000) Biochemistry , vol.39 , pp. 6380-6389
    • Hollenbeck, J.J.1    Oakley, M.G.2
  • 30
    • 0028892084 scopus 로고
    • A role for Hsp90 in retinoid receptor signal transduction
    • Holley SJ, Yamamoto KR (1995) A role for Hsp90 in retinoid receptor signal transduction. Mol Biol Cell 6: 1833-1842.
    • (1995) Mol Biol Cell , vol.6 , pp. 1833-1842
    • Holley, S.J.1    Yamamoto, K.R.2
  • 31
    • 0028009237 scopus 로고
    • Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region
    • Hsu W, Kerppola TK, Chen PL, Curran T, Chen-Kiang S (1994) Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region. Mol Cell Biol 14: 268-276.
    • (1994) Mol Cell Biol , vol.14 , pp. 268-276
    • Hsu, W.1    Kerppola, T.K.2    Chen, P.L.3    Curran, T.4    Chen-Kiang, S.5
  • 32
    • 0030808558 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response
    • Kawahara T, Yanagi H, Yura T, Mori K (1997) Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response. Mol Biol Cell 8: 1845-1862.
    • (1997) Mol Biol Cell , vol.8 , pp. 1845-1862
    • Kawahara, T.1    Yanagi, H.2    Yura, T.3    Mori, K.4
  • 33
    • 0038349948 scopus 로고    scopus 로고
    • Sequencing and comparison of yeast species to identify genes and regulatory elements
    • Kellis M, Patterson N, Endrizzi M, Birren B, Lander ES (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423: 241-254.
    • (2003) Nature , vol.423 , pp. 241-254
    • Kellis, M.1    Patterson, N.2    Endrizzi, M.3    Birren, B.4    Lander, E.S.5
  • 34
    • 0027465942 scopus 로고
    • The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum
    • Kohno K, Normington K, Sambrook J, Gething MJ, Mori K (1993) The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum. Mol Cell Biol 13: 877-890.
    • (1993) Mol Cell Biol , vol.13 , pp. 877-890
    • Kohno, K.1    Normington, K.2    Sambrook, J.3    Gething, M.J.4    Mori, K.5
  • 35
    • 19344374214 scopus 로고    scopus 로고
    • IRE1-independent Gain Control of the Unfolded Protein Response
    • DOI: 10.1371/journal.pbio.0020235
    • Leber JH, Bernáles S, Walter P (2004) IRE1-independent Gain Control of the Unfolded Protein Response. PLoS Biol 2: e235 DOI: 10.1371/journal.pbio.0020235.
    • (2004) PLoS Biol , vol.2
    • Leber, J.H.1    Bernáles, S.2    Walter, P.3
  • 36
    • 0037083755 scopus 로고    scopus 로고
    • IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
    • Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, et al. (2002a) IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 16: 452-466.
    • (2002) Genes Dev , vol.16 , pp. 452-466
    • Lee, K.1    Tirasophon, W.2    Shen, X.3    Michalak, M.4    Prywes, R.5
  • 37
    • 0037174671 scopus 로고    scopus 로고
    • Transcriptional regulatory networks in Saccharomyces cerevisiae
    • Lee TI, Rinaldi NJ, Robert F, Odom DT, Bar-Joseph Z, et al. (2002b) Transcriptional regulatory networks in Saccharomyces cerevisiae. Science 298: 799-804.
    • (2002) Science , vol.298 , pp. 799-804
    • Lee, T.I.1    Rinaldi, N.J.2    Robert, F.3    Odom, D.T.4    Bar-Joseph, Z.5
  • 38
    • 0034637605 scopus 로고    scopus 로고
    • Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum
    • Liu CY, Schroder M, Kaufman RJ (2000) Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum. J Biol Chem 275: 24881-24885.
    • (2000) J Biol Chem , vol.275 , pp. 24881-24885
    • Liu, C.Y.1    Schroder, M.2    Kaufman, R.J.3
  • 39
    • 0031820288 scopus 로고    scopus 로고
    • Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
    • Longtine MS, McKenzieA 3rd, Demarini DJ, Shah NG, Wach A, et al. (1998) Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14: 953-961.
    • (1998) Yeast , vol.14 , pp. 953-961
    • Longtine, M.S.1    McKenzie III, A.2    Demarini, D.J.3    Shah, N.G.4    Wach, A.5
  • 40
    • 0036314984 scopus 로고    scopus 로고
    • Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response
    • Ma Y, Brewer JW, Diehl JA, Hendershot LM (2002) Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response. J Mol Biol 318: 1351-1365.
    • (2002) J Mol Biol , vol.318 , pp. 1351-1365
    • Ma, Y.1    Brewer, J.W.2    Diehl, J.A.3    Hendershot, L.M.4
  • 41
    • 0021646202 scopus 로고
    • The role of DNA replication in the repression of the yeast mating-type silent loci
    • Miller AM, Sternglanz R, Nasmyth KA (1984) The role of DNA replication in the repression of the yeast mating-type silent loci. Cold Spring Harb Symp Quant Biol 49: 105-113.
    • (1984) Cold Spring Harb Symp Quant Biol , vol.49 , pp. 105-113
    • Miller, A.M.1    Sternglanz, R.2    Nasmyth, K.A.3
  • 42
    • 18344404685 scopus 로고    scopus 로고
    • Characterization of mouse Ire1 alpha: Cloning, mRNA localization in the brain and functional analysis in a neural cell line
    • Miyoshi K, Katayama T, Imaizumi K, Taniguchi M, Mori Y, et al. (2000) Characterization of mouse Ire1 alpha: Cloning, mRNA localization in the brain and functional analysis in a neural cell line. Brain Res Mol Brain Res 85: 68-76.
    • (2000) Brain Res Mol Brain Res , vol.85 , pp. 68-76
    • Miyoshi, K.1    Katayama, T.2    Imaizumi, K.3    Taniguchi, M.4    Mori, Y.5
  • 43
    • 0026628290 scopus 로고
    • A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins
    • Mori K, Sant A, Kohno K, Normington K, Gething MJ, et al. (1992) A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. Embo J 11: 2583-2593.
    • (1992) Embo J , vol.11 , pp. 2583-2593
    • Mori, K.1    Sant, A.2    Kohno, K.3    Normington, K.4    Gething, M.J.5
  • 44
    • 0027305620 scopus 로고
    • A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
    • Mori K, Ma W, Gething MJ, Sambrook J (1993) A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 74: 743-756.
    • (1993) Cell , vol.74 , pp. 743-756
    • Mori, K.1    Ma, W.2    Gething, M.J.3    Sambrook, J.4
  • 45
    • 0030228708 scopus 로고    scopus 로고
    • Signalling from endoplasmic reticulum to nucleus: Transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway
    • Mori K, Kawahara T, Yoshida H, Yanagi H, Yura T (1996) Signalling from endoplasmic reticulum to nucleus: Transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway. Genes Cells 1: 803-817.
    • (1996) Genes Cells , vol.1 , pp. 803-817
    • Mori, K.1    Kawahara, T.2    Yoshida, H.3    Yanagi, H.4    Yura, T.5
  • 46
    • 0032540253 scopus 로고    scopus 로고
    • Palindrome with spacer of one nucleotide is characteristic of the cis-acting unfolded protein response element in Saccharomyces cerevisiae
    • Mori K, Ogawa N, Kawahara T, Yanagi H, Yura T (1998) Palindrome with spacer of one nucleotide is characteristic of the cis-acting unfolded protein response element in Saccharomyces cerevisiae. J Biol Chem 273: 9912-9920.
    • (1998) J Biol Chem , vol.273 , pp. 9912-9920
    • Mori, K.1    Ogawa, N.2    Kawahara, T.3    Yanagi, H.4    Yura, T.5
  • 47
    • 0034973590 scopus 로고    scopus 로고
    • Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast
    • Natarajan K, Meyer MR, Jackson BM, Slade D, Roberts C, et al. (2001) Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast. Mol Cell Biol 21: 4347-4368.
    • (2001) Mol Cell Biol , vol.21 , pp. 4347-4368
    • Natarajan, K.1    Meyer, M.R.2    Jackson, B.M.3    Slade, D.4    Roberts, C.5
  • 48
    • 0035370949 scopus 로고    scopus 로고
    • Intracellular signaling from the endoplasmic reticulum to the nucleus: The unfolded protein response in yeast and mammals
    • Patil C, Walter P (2001) Intracellular signaling from the endoplasmic reticulum to the nucleus: The unfolded protein response in yeast and mammals. Curr Opin Cell Biol 13: 349-355.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 349-355
    • Patil, C.1    Walter, P.2
  • 49
    • 0027351256 scopus 로고
    • The bZIP domains of Fos and Jun mediate a physical association with the TATA box-binding protein
    • Ransone LJ, Kerr LD, Schmitt MJ, Wamsley P, Verma IM (1993) The bZIP domains of Fos and Jun mediate a physical association with the TATA box-binding protein. Gene Expr 3: 37-48.
    • (1993) Gene Expr , vol.3 , pp. 37-48
    • Ransone, L.J.1    Kerr, L.D.2    Schmitt, M.J.3    Wamsley, P.4    Verma, I.M.5
  • 50
    • 0035812716 scopus 로고    scopus 로고
    • Block of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response
    • Ruegsegger U, Leber JH, Walter P (2001) Block of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response. Cell 107: 103-114.
    • (2001) Cell , vol.107 , pp. 103-114
    • Ruegsegger, U.1    Leber, J.H.2    Walter, P.3
  • 52
    • 0030954870 scopus 로고    scopus 로고
    • The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
    • Sidrauski C, Walter P (1997) The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 90: 1031-1039.
    • (1997) Cell , vol.90 , pp. 1031-1039
    • Sidrauski, C.1    Walter, P.2
  • 53
    • 0030297538 scopus 로고    scopus 로고
    • tRNA ligase is required for regulated mRNA splicing in the unfolded protein response
    • Sidrauski C, Cox JS, Walter P (1996) tRNA ligase is required for regulated mRNA splicing in the unfolded protein response. Cell 87: 405-413.
    • (1996) Cell , vol.87 , pp. 405-413
    • Sidrauski, C.1    Cox, J.S.2    Walter, P.3
  • 54
    • 0034871249 scopus 로고    scopus 로고
    • Endoproteolysis of the ER stress transducer ATF6 in the presence of functionally inactive presenilins
    • Steiner H, Winkler E, Shearman MS, Prywes R, Haass C (2001) Endoproteolysis of the ER stress transducer ATF6 in the presence of functionally inactive presenilins. Neurobiol Dis 8: 717-722.
    • (2001) Neurobiol Dis , vol.8 , pp. 717-722
    • Steiner, H.1    Winkler, E.2    Shearman, M.S.3    Prywes, R.4    Haass, C.5
  • 55
    • 0035862974 scopus 로고    scopus 로고
    • The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4
    • Stitzel ML, Durso R, Reese JC (2001) The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4. Genes Dev 15: 128-133.
    • (2001) Genes Dev , vol.15 , pp. 128-133
    • Stitzel, M.L.1    Durso, R.2    Reese, J.C.3
  • 56
    • 0030016386 scopus 로고    scopus 로고
    • Genetic evidence for functional specificity of the yeast GCN2 kinase
    • Tavernarakis N, Thireos G (1996) Genetic evidence for functional specificity of the yeast GCN2 kinase. Mol Gen Genet 251: 613-618.
    • (1996) Mol Gen Genet , vol.251 , pp. 613-618
    • Tavernarakis, N.1    Thireos, G.2
  • 57
    • 0034724520 scopus 로고    scopus 로고
    • Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
    • Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, et al. (2000) Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 101: 249-258.
    • (2000) Cell , vol.101 , pp. 249-258
    • Travers, K.J.1    Patil, C.K.2    Wodicka, L.3    Lockhart, D.J.4    Weissman, J.S.5
  • 58
    • 0033693855 scopus 로고    scopus 로고
    • IRE1 and efferent signaling from the endoplasmic reticulum
    • Urano F, Bertolotti A, Ron D (2000) IRE1 and efferent signaling from the endoplasmic reticulum. J Cell Sci 113: 3697-3702.
    • (2000) J Cell Sci , vol.113 , pp. 3697-3702
    • Urano, F.1    Bertolotti, A.2    Ron, D.3
  • 59
    • 0032190546 scopus 로고    scopus 로고
    • Cloning of mammalian Ire1 reveals diversity in the ER stress responses
    • Wang XZ, Harding HP, Zhang Y, Jolicoeur EM, Kuroda M, et al. (1998) Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J 17: 5708-5717.
    • (1998) EMBO J , vol.17 , pp. 5708-5717
    • Wang, X.Z.1    Harding, H.P.2    Zhang, Y.3    Jolicoeur, E.M.4    Kuroda, M.5
  • 60
    • 0034282912 scopus 로고    scopus 로고
    • Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response
    • Wang Y, Shen J, Arenzana N, Tirasophon W, Kaufman RJ, et al. (2000) Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. J Biol Chem 275: 27013-27020.
    • (2000) J Biol Chem , vol.275 , pp. 27013-27020
    • Wang, Y.1    Shen, J.2    Arenzana, N.3    Tirasophon, W.4    Kaufman, R.J.5
  • 61
    • 0034028905 scopus 로고    scopus 로고
    • Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase
    • Yang R, Wek SA, Wek RC (2000) Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase. Mol Cell Biol 20: 2706-2717.
    • (2000) Mol Cell Biol , vol.20 , pp. 2706-2717
    • Yang, R.1    Wek, S.A.2    Wek, R.C.3
  • 62
    • 0034515724 scopus 로고    scopus 로고
    • ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
    • Ye J, Rawson RB, Komuro R, Chen X, Dave UP, et al. (2000) ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell 6: 1355-1364.
    • (2000) Mol Cell , vol.6 , pp. 1355-1364
    • Ye, J.1    Rawson, R.B.2    Komuro, R.3    Chen, X.4    Dave, U.P.5
  • 63
    • 0035141230 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response
    • Yoshida H, Okada T, Haze K, Yanagi H, Yura T, et al. (2001) Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response. Mol Cell Biol 21: 1239-1248.
    • (2001) Mol Cell Biol , vol.21 , pp. 1239-1248
    • Yoshida, H.1    Okada, T.2    Haze, K.3    Yanagi, H.4    Yura, T.5


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