Structural analysis of cytochrome P450 105N1 involved in the biosynthesis of the zincophore, coelibactin

International Journal of Molecular Sciences

Volumn 13, Issue 7, 2012, Pages 8500-8513

  Zhao, Bin ^a   Moody, Suzy C ^b   Hider, Robert C ^c   Lei, Li ^a   Kelly, Steven L ^b   Waterman, Michael R ^a   Lamb, David C ^b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SWANSEA UNIVERSITY   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

CYP105N1; Cytochrome P450; Siderophore; Streptomyces coelicolor A3(2); Zinc chelation

Indexed keywords

COELIBACTIN; CYTOCHROME P450; NONRIBOSOMAL PEPTIDE SYNTHETASE; UNCLASSIFIED DRUG; ZINC; BACTERIAL PROTEIN; OXAZOLE DERIVATIVE; SIDEROPHORE; THIAZOLE DERIVATIVE;

ALPHA HELIX; ARTICLE; BETA SHEET; BIOINFORMATICS; BIOSYNTHESIS; CHELATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; OXYGENATION; PROTEIN EXPRESSION; STEREOSPECIFICITY; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; PROTEIN SECONDARY STRUCTURE; STREPTOMYCES COELICOLOR; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); STREPTOMYCES COELICOLOR;

BACTERIAL PROTEINS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; MODELS, MOLECULAR; OXAZOLES; PROTEIN STRUCTURE, SECONDARY; SIDEROPHORES; STREPTOMYCES COELICOLOR; THIAZOLES; ZINC;

EID: 84864352700     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13078500     Document Type: Article

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