Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3(2) cytochrome P450 158A2

Journal of Biological Chemistry

Volumn 280, Issue 12, 2005, Pages 11599-11607

  Zhao, Bin ^a,b   Guengerich, F Peter ^a   Bellamine, Aouatef ^a   Lamb, David C ^c   Izumikawa, Miho ^d   Lei, Li ^a   Podust, Larissa M ^a   Sundaramoorthy, Munirathinam ^a,b   Kalaitzis, John A ^d   Reddy, L Manmohan ^e   Kelly, Steven L ^c   Moore, Bradley S ^d   Stec, Donald ^f   Voehler, Markus ^f   Falck, John R ^e   Shimada, Tsutomu ^a   Waterman, Michael R ^a  

^a Department of Biochemistry ^*  (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SWANSEA UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF ARIZONA   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOCHEMISTRY; CHEMICAL BONDS; CLONING; CRYSTAL STRUCTURE; DIMERS; ENZYMES; GENES; MASS SPECTROMETRY; MOLECULAR BIOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION; PHENOLS; PURIFICATION; SOILS; ULTRAVIOLET RADIATION;

CYTOCHROME; FLAVIOLIN; MICROBES; OXIDATIVE COUPLING; TRIMERS;

PIGMENTS;

CYTOCHROME P450; CYTOCHROME P450 CYP158A2; DIMER; FLAVIOLIN; HEME; PIGMENT; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; COVALENT BOND; CRYSTAL STRUCTURE; LIGAND BINDING; MASS SPECTROMETRY; MOLECULAR CLONING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; STREPTOMYCES COELICOLOR; STRUCTURE ANALYSIS; X RAY ANALYSIS;

CRYSTALLIZATION; CYTOCHROME P-450 ENZYME SYSTEM; DIMERIZATION; NAPHTHOQUINONES; OXIDATION-REDUCTION; PROTEIN CONFORMATION; STREPTOMYCES COELICOLOR;

BACTERIA (MICROORGANISMS); STREPTOMYCES COELICOLOR; STREPTOMYCINEAE;

EID: 20144369362     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410933200     Document Type: Article

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