Exploiting Streptomyces coelicolor A3(2) P450s as a model for application in drug discovery

Expert Opinion on Drug Metabolism and Toxicology

Volumn 2, Issue 1, 2006, Pages 27-40

  Lamb, David C ^b   Guengerich, F Peter ^a   Kelly, Steven L ^b   Waterman, Michael R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SWANSEA UNIVERSITY   (United Kingdom)

Author keywords

Antibiotics; Cytochrome P450; Metabolism; Streptomyces; Xenobiotics

Indexed keywords

CYTOCHROME P450; MICROBIAL ENZYME;

ACTINOBACTERIA; BIOMEDICINE; DRUG INDUSTRY; DRUG SYNTHESIS; GENE LOCUS; GENOMICS; NONHUMAN; REVIEW; STREPTOMYCES COELICOLOR;

ANIMALS; BACTERIAL PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; HUMANS; MODELS, CHEMICAL; STREPTOMYCES COELICOLOR;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); STREPTOMYCES; STREPTOMYCES AVERMITILIS; STREPTOMYCES COELICOLOR; STREPTOMYCES PEUCETIUS; STREPTOMYCINEAE;

EID: 33846234743     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425255.2.1.27     Document Type: Review

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