Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repair

Molecular Biology Reports

Volumn 39, Issue 7, 2012, Pages 7487-7496

  Blasiak, Janusz ^a   Synowiec, Ewelina ^a   Tarnawska, Justyna ^a   Czarny, Piotr ^a   Poplawski, Tomasz ^a   Reiter, Russel J ^b  

^a UNIVERSITY OF LODZ   (Poland)

^b Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

2 hydroxyethyl methacrylate; Bis GMA; Bisphenol A diglycidyl dimethacrylate; DNA damage; DNA double strand breaks; DNA repair; HEMA; Melatonin; Methacrylate based dental materials; Vitamin C

Indexed keywords

2 HYDROXYETHYL METHACRYLATE; 8 HYDROXYGUANINE; ADHESIVE AGENT; ASCORBIC ACID; BISPHENOL A BIS(2 HYDROXYPROPYL) ETHER DIMETHACRYLATE; DNA GLYCOSYLTRANSFERASE; HISTONE H2AX; HYDROGEN PEROXIDE; MELATONIN;

APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL POPULATION; COMET ASSAY; CONTROLLED STUDY; DENTISTRY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; FIBROBLAST CULTURE; GENOTOXICITY; GINGIVA; HISTONE PHOSPHORYLATION; HUMAN; HUMAN CELL; OXIDATION;

APOPTOSIS; ASCORBIC ACID; CELL CYCLE CHECKPOINTS; CELL LINE; COMPOSITE RESINS; DENTAL CEMENTS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; GINGIVA; HUMANS; MELATONIN; METHACRYLATES; MUTAGENS;

EID: 84864289579     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1582-3     Document Type: Article

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