메뉴 건너뛰기




Volumn 61, Issue 3, 2012, Pages 310-320

Attenuation of NF-κβ mediated apoptotic signaling by tocotrienol ameliorates cognitive deficits in rats postnatally exposed to ethanol

Author keywords

Alcohol; Apoptosis; Caspase 3; Cognitive deficits; Fetal alcohol spectrum disorders (FASDs); Neuroinflammation; Nuclear factor kappa beta (NF ); Oxidative stress; Tocotrienol

Indexed keywords

ACETYLCHOLINESTERASE; ALCOHOL; ALPHA TOCOTRIENOL; CASPASE 3; INTERLEUKIN 1BETA; LIPID PEROXIDE; NITRITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84864261949     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.05.010     Document Type: Article
Times cited : (21)

References (59)
  • 1
    • 3142550700 scopus 로고    scopus 로고
    • Paternal contribution to fetal alcohol syndrome
    • DOI 10.1080/13556210410001716980
    • E. Abel Paternal contribution to fetal alcohol syndrome Addict. biol. 9 2004 127 133 (Pubitemid 38901594)
    • (2004) Addiction Biology , vol.9 , Issue.2 , pp. 127-133
    • Abel, E.L.1
  • 2
    • 0029128854 scopus 로고
    • Maternal risk factors in Fetal Alcohol Syndrome: Provocative and permissive influences
    • E.L. Abel, and J.H. Hannigan Maternal risk factors in Fetal Alcohol Syndrome: provocative and permissive influences Neurotoxicol. Teratol. 17 1995 445 462
    • (1995) Neurotoxicol. Teratol. , vol.17 , pp. 445-462
    • Abel, E.L.1    Hannigan, J.H.2
  • 3
    • 0025733958 scopus 로고
    • A revised conservative estimate of the incidence of FAS and its economic impact
    • E.L. Abel, and R.J. Sokol A revised conservative estimate of the incidence of FAS and its economic impact Alcohol Clin. Exp. Res. 15 1991 514 524
    • (1991) Alcohol Clin. Exp. Res. , vol.15 , pp. 514-524
    • Abel, E.L.1    Sokol, R.J.2
  • 4
    • 41649112271 scopus 로고    scopus 로고
    • Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons
    • A.M. Antonio, and M.J. Druse Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons Brain Res. 1204 2008 16 23
    • (2008) Brain Res. , vol.1204 , pp. 16-23
    • Antonio, A.M.1    Druse, M.J.2
  • 5
    • 0024441725 scopus 로고
    • Effects of ethanol on muscarinic receptor-stimulated phosphoinositide metabolism during brain development
    • W. Balduini, and L.G. Costa Effect of ethanol on muscarinic receptor-stimulated phosphoinositide metabolism during brain development J. Pharmacol. Exp. Ther. 250 1989 541 547 (Pubitemid 19216138)
    • (1989) Journal of Pharmacology and Experimental Therapeutics , vol.250 , Issue.2 , pp. 541-547
    • Balduini, W.1    Costa, L.G.2
  • 6
    • 0029756595 scopus 로고    scopus 로고
    • Purkinje cell deficits in nonhuman primates following weekly exposure to ethanol during gestation
    • DOI 10.1002/(SICI)1096-9926(199604)53:4<230::AID-TERA5>3.0.CO;2-6
    • D.J. Bonthius, N.E. Bonthius, R.M. Napper, S.J. Astley, S.K. Clarren, and J.R. West Purkinje cell deficits in nonhuman primates following weekly exposure to ethanol during gestation Teratology 53 1996 230 236 (Pubitemid 26278812)
    • (1996) Teratology , vol.53 , Issue.4 , pp. 230-236
    • Bonthius, D.J.1    Bonthius, N.E.2    Napper, R.M.A.3    Astley, S.J.4    Clarren, S.K.5    West, J.R.6
  • 8
    • 0033042862 scopus 로고    scopus 로고
    • Muscarinic cholinergic receptor signal transduction as a potential target for the developmental neurotoxicity of ethanol
    • DOI 10.1016/S0006-2952(98)00278-0, PII S0006295298002780
    • L.G. Costa, and M. Guizzetti Muscarinic cholinergic receptor signal transduction as a potential target for the developmental neurotoxicity of ethanol Biochem. Pharmacol. 57 1999 721 726 (Pubitemid 29094543)
    • (1999) Biochemical Pharmacology , vol.57 , Issue.7 , pp. 721-726
    • Costa, L.G.1    Guizzetti, M.2
  • 10
    • 14844288299 scopus 로고    scopus 로고
    • Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures
    • DOI 10.1016/j.devbrainres.2004.11.005
    • K. Dikranian, Y.Q. Qin, J. Labruyere, B. Nemmers, and J.W. Olney Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures Brain Res. Dev. Brain Res. 155 2005 1 13 (Pubitemid 40342947)
    • (2005) Developmental Brain Research , vol.155 , Issue.1 , pp. 1-13
    • Dikranian, K.1    Qin, Y.-Q.2    Labruyere, J.3    Nemmers, B.4    Olney, J.W.5
  • 11
    • 2442465817 scopus 로고    scopus 로고
    • The serotonin-1A agonist ipsapirone prevents ethanol-associated death of total rhombencephalic neurons and prevents the reduction of fetal serotonin neurons
    • DOI 10.1016/j.devbrainres.2004.02.009, PII S0165380604000756
    • M.J. Druse, N.F. Tajuddin, R.A. Gillespie, E. Dickson, M. Atieh, C.A. Pietrzak, and P.T. Le The serotonin-1A agonist ipsapirone prevents ethanol-associated death of total rhombencephalic neurons and prevents the reduction of fetal serotonin neurons Brain Res. Dev. Brain Res. 150 2004 79 88 (Pubitemid 38639813)
    • (2004) Developmental Brain Research , vol.150 , Issue.2 , pp. 79-88
    • Druse, M.J.1    Tajuddin, N.F.2    Gillespie, R.A.3    Dickson, E.4    Atieh, M.5    Pietrzak, C.A.6    Le, P.T.7
  • 13
    • 0028824465 scopus 로고
    • Sex differences in vulnerability to developmental spatial learning deficits induced by limited binge alcohol exposure in neonatal rats
    • C.R. Goodlett, and S.D. Peterson Sex differences in vulnerability to developmental spatial learning deficits induced by limited binge alcohol exposure in neonatal rats Neurobiol. Learn Mem. 64 1995 265 275
    • (1995) Neurobiol. Learn Mem. , vol.64 , pp. 265-275
    • Goodlett, C.R.1    Peterson, S.D.2
  • 14
    • 0020448709 scopus 로고
    • 15N]nitrate in biological fluids
    • DOI 10.1016/0003-2697(82)90118-X
    • L.C. Green, D.A. Wagner, J. Glogowski, P.L. Skipper, J.S. Wishnok, and S.R. Tannenbaum Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids Anal. Biochem. 126 1982 131 138 (Pubitemid 13203451)
    • (1982) Analytical Biochemistry , vol.126 , Issue.1 , pp. 131-138
    • Green, L.C.1    Wagner, D.A.2    Glogowski, J.3
  • 15
    • 0031980790 scopus 로고    scopus 로고
    • Neuroanatomical and neurophysiological mechanisms involved in central nervous system dysfunctions induced by prenatal alcohol exposure
    • DOI 10.1111/j.1530-0277.1998.tb03653.x
    • C. Guerri Neuroanatomical and neurophysiological mechanisms involved in central nervous system dysfunctions induced by prenatal alcohol exposure Alcohol Clin. Exp. Res. 22 1998 304 312 (Pubitemid 28208950)
    • (1998) Alcoholism: Clinical and Experimental Research , vol.22 , Issue.2 , pp. 304-312
    • Guerri, C.1
  • 16
    • 0036619408 scopus 로고    scopus 로고
    • Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure
    • C. Guerri Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure Neurotoxicol. Teratol. 4 2002 327 335
    • (2002) Neurotoxicol. Teratol. , vol.4 , pp. 327-335
    • Guerri, C.1
  • 17
    • 0034012035 scopus 로고    scopus 로고
    • Amelioration of ethanol-induced neurotoxicity in the neonatal rat central nervous system by antioxidant therapy
    • M.B. Heaton, J.J. Mitchell, and M. Paiva Amelioration of ethanol-induced neurotoxicity in the neonatal rat central nervous system by antioxidant therapy Alcohol Clin. Exp. Res. 24 2000 512 518 (Pubitemid 30244250)
    • (2000) Alcoholism: Clinical and Experimental Research , vol.24 , Issue.4 , pp. 512-518
    • Heaton, M.B.1    Mitchell, J.J.2    Paiva, M.3
  • 18
    • 0242384139 scopus 로고    scopus 로고
    • Ethanol effects on neonatal rat cortex: Comparative analyses of neurotrophic factors, apoptosis-related proteins, and oxidative processes during vulnerable and resistant periods
    • DOI 10.1016/j.devbrainres.2003.08.005
    • M.B. Heaton, M. Paiva, I. Madorsky, and G. Shaw Ethanol effects on neonatal rat cortex: comparative analyses of neurotrophic factors, apoptosis-related proteins, and oxidative processes during vulnerable and resistant periods Brain Res. Dev. Brain Res. 145 2003 249 262 (Pubitemid 37357134)
    • (2003) Developmental Brain Research , vol.145 , Issue.2 , pp. 249-262
    • Heaton, M.B.1    Paiva, M.2    Madorsky, I.3    Shaw, G.4
  • 19
    • 0033563527 scopus 로고    scopus 로고
    • Ethanol, oxidative stress, reactive aldehydes, and the fetus
    • G.I. Henderson, J.J. Chen, and S. Schenker Ethanol, oxidative stress, reactive aldehydes, and the fetus Front Biosci. 4 1999 541 550
    • (1999) Front Biosci. , vol.4 , pp. 541-550
    • Henderson, G.I.1    Chen, J.J.2    Schenker, S.3
  • 20
    • 0034635370 scopus 로고    scopus 로고
    • Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome
    • DOI 10.1126/science.287.5455.1056
    • C. Ikonomidou, P. Bittigau, M.J. Ishimaru, D.F. Wozniak, C. Koch, K. Genz, M.T. Price, V. Stefovska, F. Hörster, T. Tenkova, K. Dikranian, and J.W. Olney Ethanol-induced apoptotic neurodegeneration and the fetal alcohol syndrome Science 287 2000 1056 1060 (Pubitemid 30094364)
    • (2000) Science , vol.287 , Issue.5455 , pp. 1056-1060
    • Ikonomidou, C.1    Bittigau, P.2    Koch, C.3    Genz, K.4    Stefovska, V.5    Horster, F.6
  • 22
    • 26944466394 scopus 로고    scopus 로고
    • A single day of ethanol exposure during development has persistent effects on bi-directional plasticity, N-methyl-D-aspartate receptor function and ethanol sensitivity
    • DOI 10.1016/j.neuroscience.2005.07.015, PII S0306452205007657
    • Y. Izumi, R. Kitabayashi, M. Funatsu, M. Izumi, C. Yuede, R.E. Hartman, D.F. Wozniak, and C.F. Zorumski A single day of ethanol exposure during development has persistent effects on bi-directional plasticity, N-methyl-d-aspartate receptor function and ethanol sensitivity Neuroscience 136 2005 269 279 (Pubitemid 41483854)
    • (2005) Neuroscience , vol.136 , Issue.1 , pp. 269-279
    • Izumi, Y.1    Kitabayashi, R.2    Funatsu, M.3    Izumi, M.4    Yuede, C.5    Hartman, R.E.6    Wozniak, D.F.7    Zorumski, C.F.8
  • 24
    • 0016151122 scopus 로고
    • Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3,4-bromobenzenoxide as the hepatotoxic intermediate
    • D.J. Jollow, J.R. Mitchell, N. Zampaglione, and J.R. Gillette Bromobenzene induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobenzenoxide as the hepatotoxic intermediate Pharmacology 11 1974 151 169
    • (1974) Pharmacology , vol.11 , pp. 151-169
    • Jollow, D.J.1    Mitchell, J.R.2    Zampaglione, N.3    Gillette, J.R.4
  • 25
    • 11144278296 scopus 로고    scopus 로고
    • Estrogen neuroprotection against the neurotoxic effects of ethanol withdrawal: Potential mechanisms
    • M.E. Jung, M.B. Gatch, and J.W. Simpkins Estrogen neuroprotection against the neurotoxic effects of ethanol withdrawal: potential mechanisms Exp. Biol. Med. 230 2005 8 22 (Maywood, N.J.) (Pubitemid 40041067)
    • (2005) Experimental Biology and Medicine , vol.230 , Issue.1 , pp. 8-22
    • Jung, M.E.1    Gatch, M.B.2    Simpkins, J.W.3
  • 26
    • 0242290274 scopus 로고    scopus 로고
    • Molecular Basis of Vitamin E Action: Tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration
    • DOI 10.1074/jbc.M307075200
    • S. Khanna, S. Roy, H. Ryu, P. Bahadduri, P.W. Swaan, R.R. Ratan, and C.K. Sen Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration J. Biol. Chem. 278 2003 43508 43515 (Pubitemid 37345974)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.44 , pp. 43508-43515
    • Khanna, S.1    Roy, S.2    Ryu, H.3    Bahadduri, P.4    Swaan, P.W.5    Ratan, R.R.6    Sent, C.K.7
  • 27
    • 0017804313 scopus 로고
    • Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase
    • Y. Kono Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase Arch. Biochem. Biophys. 186 1978 189 195 (Pubitemid 8290500)
    • (1978) Archives of Biochemistry and Biophysics , vol.186 , Issue.1 , pp. 189-195
    • Kono, Y.1
  • 28
    • 0036344646 scopus 로고    scopus 로고
    • Intracerebroventricular administration of colchicine produces cognitive impairment associated with oxidative stress in rats
    • DOI 10.1016/S0091-3057(02)00838-9, PII S0091305702008389
    • V.M.H. Kumar, and Y.K. Gupta Intracerebroventricular administration of colchicine produces cognitive impairment associated with oxidative stress in rats Pharmacol. Biochem. Behav. 73 2002 565 571 (Pubitemid 34879162)
    • (2002) Pharmacology Biochemistry and Behavior , vol.73 , Issue.3 , pp. 565-571
    • Veerendra Kumar, M.H.1    Gupta, Y.K.2
  • 29
    • 59649122815 scopus 로고    scopus 로고
    • Suppression of NF-κβ signaling pathway by tocotrienol can prevent diabetes associated cognitive deficits
    • A. Kuhad, M. Bishnoi, V. Tiwari, and K. Chopra Suppression of NF-κβ signaling pathway by tocotrienol can prevent diabetes associated cognitive deficits Pharmacol. Biochem. Behav. 92 2009 251 259
    • (2009) Pharmacol. Biochem. Behav. , vol.92 , pp. 251-259
    • Kuhad, A.1    Bishnoi, M.2    Tiwari, V.3    Chopra, K.4
  • 30
  • 31
    • 23944491627 scopus 로고    scopus 로고
    • Prenatal alcohol exposure alters the size, but not the pattern, of the whisker representation in neonatal rat barrel cortex
    • DOI 10.1007/s00221-005-2287-9
    • C.P. Margret, C.X. Li, A.J. Elberger, S.G. Matta, T.D. Chappell, and R.S. Waters Prenatal alcohol exposure alters the size, but not the pattern, of the whisker representation in neonatal rat barrel cortex Exp. Brain Res. 165 2005 167 178 (Pubitemid 41206967)
    • (2005) Experimental Brain Research , vol.165 , Issue.2 , pp. 167-178
    • Margret, C.P.1    Li, C.X.2    Elberger, A.J.3    Matta, S.G.4    Chappell, T.D.5    Waters, R.S.6
  • 32
    • 4544385484 scopus 로고    scopus 로고
    • Vitamin E protects against alcohol-induced cell loss and oxidative stress in the neonatal rat hippocampus
    • DOI 10.1016/j.ijdevneu.2004.04.005, PII S0736574804000425, Developmental Aspects of Addiction
    • M.D. Marino, M.Y. Aksenov, and S.J. Kelly Vitamin E protects against alcohol-induced cell loss and oxidative stress in the neonatal rat hippocampus Int. J. Dev. Neurosci. 22 2004 363 377 (Pubitemid 39233544)
    • (2004) International Journal of Developmental Neuroscience , vol.22 , Issue.5-6 , pp. 363-377
    • Marino, M.D.1    Aksenov, M.Y.2    Kelly, S.J.3
  • 33
    • 0033048731 scopus 로고    scopus 로고
    • The antioxidants vitamin e and β-carotene protect against ethanol- induced neurotoxicity in embryonic rat hippocampal cultures
    • DOI 10.1016/S0741-8329(98)00051-2, PII S0741832998000512
    • J.J. Mitchell, M. Paiva, and M.B. Heaton The antioxidants vitamin E and beta-carotene protect against ethanol-induced neurotoxicity in embryonic rat hippocampal cultures Alcohol 17 1999 163 168 (Pubitemid 29096205)
    • (1999) Alcohol , vol.17 , Issue.2 , pp. 163-168
    • Mitchell, J.J.1    Paiva, M.2    Heaton, M.B.3
  • 34
    • 0019957779 scopus 로고
    • Place navigation impaired in rats with hippocampal lesions
    • DOI 10.1038/297681a0
    • R.G. Morris, P. Garrud, J.N. Rawlins, and J. O'Keefe Place navigation impaired in rats with hippocampal lesions Nature 297 1982 681 683 (Pubitemid 12096189)
    • (1982) Nature , vol.297 , Issue.5868 , pp. 681-683
    • Morris, R.G.M.1    Garrud, P.2    Rawlins, J.N.P.3    O'Keefe, J.4
  • 35
    • 0028143741 scopus 로고
    • Muscarinic stimulation promotes cultured Purkinje cell survival: A role for acetylcholine in cerebellar development?
    • H.T.J. Mount, C.F. Dreyfus, and I.B. Black Muscarinic stimulation promotes cultured Purkinje cell survival: A role for acetylcholine in cerebellar development? J. Neurochem. 63 1994 2065 2073 (Pubitemid 24369979)
    • (1994) Journal of Neurochemistry , vol.63 , Issue.6 , pp. 2065-2073
    • Mount, H.T.J.1    Dreyfus, C.F.2    Black, I.B.3
  • 36
    • 0141510019 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial complex I due to peroxynitrite: Identification of reactive tyrosines by mass spectrometry
    • DOI 10.1074/jbc.M305694200
    • J. Murray, S.W. Taylor, B. Zhang, S.S. Ghosh, and R.A. Capaldi Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry J. Biol. Chem. 278 2003 37223 37230 (Pubitemid 37175238)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.39 , pp. 37223-37230
    • Murray, J.1    Taylor, S.W.2    Zhang, B.3    Ghosh, S.S.4    Capaldi, R.A.5
  • 38
    • 3142548954 scopus 로고    scopus 로고
    • Fetal alcohol syndrome at the cellular level
    • DOI 10.1080/13556210410001717006
    • J.W. Olney Fetal alcohol syndrome at the cellular level Addict. Biol. 9 2004 137 149 discussion 151 (Pubitemid 38901596)
    • (2004) Addiction Biology , vol.9 , Issue.2 , pp. 137-149
    • Olney, J.W.1
  • 39
    • 7444250188 scopus 로고    scopus 로고
    • α-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons
    • DOI 10.1016/j.neuropharm.2004.06.029, PII S0028390804001923
    • F. Osakada, A. Hashino, T. Kume, H. Katsuki, S. Kaneko, and A. Akaike Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons Neuropharmacology 47 2004 904 915 (Pubitemid 39440984)
    • (2004) Neuropharmacology , vol.47 , Issue.6 , pp. 904-915
    • Osakada, F.1    Hashino, A.2    Kume, T.3    Katsuki, H.4    Kaneko, S.5    Akaike, A.6
  • 40
    • 77953644361 scopus 로고    scopus 로고
    • Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats
    • P. Palsamy, and S. Subramanian Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats J. Cell Physiol. 224 2 2010 423 432
    • (2010) J. Cell Physiol. , vol.224 , Issue.2 , pp. 423-432
    • Palsamy, P.1    Subramanian, S.2
  • 41
    • 0028281429 scopus 로고
    • Inhibitors of cholesterol biosynthesis. 2. Hypocholesterolemic and antioxidant activities of benzopyran and tetrahydronaphthalene analogues of the tocotrienols
    • B.C. Pearce, R.A. Parker, M.E. Deason, D.D. Dischino, E. Gillespie, A.A. Qureshi, K. Volk, and J.J. Wright Inhibitors of cholesterol biosynthesis. 2. Hypocholesterolemic and antioxidant activities of benzopyran and tetrahydronaphthalene analogues of the tocotrienols J. Med. Chem. 37 1994 526 541 (Pubitemid 24094834)
    • (1994) Journal of Medicinal Chemistry , vol.37 , Issue.4 , pp. 526-541
    • Pearce, B.C.1    Parker, R.A.2    Deason, M.E.3    Dischino, D.D.4    Gillespie, E.5    Qureshi, A.A.6    Volk, K.7    Wright, J.J.K.8
  • 42
    • 0037047476 scopus 로고    scopus 로고
    • Alpha-lipoic acid prevents ethanol-induced protein oxidation in mouse hippocampal HT22 cells
    • DOI 10.1016/S0304-3940(02)00415-9, PII S0304394002004159
    • M. Pirlich, K. Kiok, G. Sandig, H. Lochs, and T. Grune Alpha-lipoic acid prevents ethanol-induced protein oxidation in mouse hippocampal HT22 cells Neurosci. Lett. 328 2002 93 96 (Pubitemid 34804719)
    • (2002) Neuroscience Letters , vol.328 , Issue.2 , pp. 93-96
    • Pirlich, M.1    Kiok, K.2    Sandig, G.3    Lochs, H.4    Grune, T.5
  • 43
    • 43149085744 scopus 로고    scopus 로고
    • Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment
    • L. Qin, J. He, R.N. Hanes, O. Pluzarev, J.S. Hong, and F.T. Crews Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment J. Neuroinflammation 18 2008 5 10
    • (2008) J. Neuroinflammation , vol.18 , pp. 5-10
    • Qin, L.1    He, J.2    Hanes, R.N.3    Pluzarev, O.4    Hong, J.S.5    Crews, F.T.6
  • 44
    • 0242330832 scopus 로고    scopus 로고
    • Ethanol-Induced Oxidative Stress Precedes Mitochondrially Mediated Apoptotic Death of Cultured Fetal Cortical Neurons
    • DOI 10.1002/jnr.10767
    • V. Ramachandran, L.T. Watts, S.K. Maffi, J. Chen, S. Schenker, and G. Henderson Ethanol-induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons J. Neurosci. Res. 74 2003 577 588 (Pubitemid 37352080)
    • (2003) Journal of Neuroscience Research , vol.74 , Issue.4 , pp. 577-588
    • Ramachandran, V.1    Watts, L.T.2    Maffi, S.K.3    Chen, J.4    Schenker, S.5    Henderson, G.I.6
  • 45
    • 20444467726 scopus 로고    scopus 로고
    • Fetal alcohol spectrum disorders: An overview with emphasis on changes in brain and behavior
    • E.P. Rile, and C.L. McGee Fetal alcohol spectrum disorders: an overview with emphasis on changes in brain and behavior Exp. Biol. Med. (Maywood). 230 2005 357 365 (Pubitemid 40827700)
    • (2005) Experimental Biology and Medicine , vol.230 , Issue.6 , pp. 357-365
    • Riley, E.P.1    McGee, C.L.2
  • 46
    • 0034724679 scopus 로고    scopus 로고
    • Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp(60c-Src) kinase activation and death of HT4 neuronal cells
    • DOI 10.1074/jbc.275.17.13049
    • C.K. Sen, S. Khanna, S. Roy, and L. Packer Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp 60(c-Src) kinase activation and death of HT4 neuronal cells J. Biol. Chem. 275 2000 13049 13055 (Pubitemid 30241466)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.17 , pp. 13049-13055
    • Sen, C.K.1    Khanna, S.2    Roy, S.3    Packer, L.4
  • 47
    • 0025761230 scopus 로고
    • Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol
    • E. Serbinova, V. Kagan, D. Han, and L. Packer Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol Free Radic. Biol. Med. 10 1991 263 275 (Pubitemid 121003898)
    • (1991) Free Radical Biology and Medicine , vol.10 , Issue.5 , pp. 263-275
    • Serbinova, E.1    Kagan, V.2    Han, D.3    Packer, L.4
  • 48
    • 0027948428 scopus 로고
    • Antioxidant properties of alpha-tocopherol and alpha-tocotrienol
    • E.A. Serbinova, and L. Packer Antioxidant properties of alpha-tocopherol and alpha-tocotrienol Methods Enzymol. 234 1994 354 366
    • (1994) Methods Enzymol. , vol.234 , pp. 354-366
    • Serbinova, E.A.1    Packer, L.2
  • 49
    • 0037063709 scopus 로고    scopus 로고
    • Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats
    • DOI 10.1016/S0024-3205(02)02083-0, PII S0024320502020830
    • M. Sharma, and Y.K. Gupta Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats Life Sci. 71 2002 2489 2498 (Pubitemid 35251893)
    • (2002) Life Sciences , vol.71 , Issue.21 , pp. 2489-2498
    • Sharma, M.1    Gupta, Y.K.2
  • 50
    • 67650658872 scopus 로고    scopus 로고
    • Protective effect of vitamin e against ethanol-induced hyperhomocysteinemia, DNA damage, and atrophy in the developing male rat brain
    • A. Shirpoor, S. Salami, M.H. Khadem-Ansari, S. Minassian, and M. Yegiazarian Protective effect of vitamin E against ethanol-induced hyperhomocysteinemia, DNA damage, and atrophy in the developing male rat brain Alcohol Clin. Exp. Res. 33 2009 1181 1186
    • (2009) Alcohol Clin. Exp. Res. , vol.33 , pp. 1181-1186
    • Shirpoor, A.1    Salami, S.2    Khadem-Ansari, M.H.3    Minassian, S.4    Yegiazarian, M.5
  • 53
    • 79955040532 scopus 로고    scopus 로고
    • Resveratrol prevents alcohol-induced cognitive deficits and brain damage by blocking inflammatory signaling and cell death cascade in neonatal rat brain
    • V. Tiwari, and K. Chopra Resveratrol prevents alcohol-induced cognitive deficits and brain damage by blocking inflammatory signaling and cell death cascade in neonatal rat brain J. Neurochem. 117 2011 678 690
    • (2011) J. Neurochem. , vol.117 , pp. 678-690
    • Tiwari, V.1    Chopra, K.2
  • 54
    • 69049117166 scopus 로고    scopus 로고
    • Tocotrienol ameliorates behavioral and biochemical alterations in the rat model of alcoholic neuropathy
    • V. Tiwari, A. Kuhad, and K. Chopra Tocotrienol ameliorates behavioral and biochemical alterations in the rat model of alcoholic neuropathy Pain 145 2009 129 135
    • (2009) Pain , vol.145 , pp. 129-135
    • Tiwari, V.1    Kuhad, A.2    Chopra, K.3
  • 55
    • 67649641781 scopus 로고    scopus 로고
    • Suppression of neuro-inflammatory signaling cascade by tocotrienol can prevent chronic alcohol-induced cognitive dysfunction in rats
    • V. Tiwari, A. Kuhad, and K. Chopra Suppression of neuro-inflammatory signaling cascade by tocotrienol can prevent chronic alcohol-induced cognitive dysfunction in rats Behav. Brain Res. 203 2009 296 303
    • (2009) Behav. Brain Res. , vol.203 , pp. 296-303
    • Tiwari, V.1    Kuhad, A.2    Chopra, K.3
  • 56
    • 33646161716 scopus 로고    scopus 로고
    • Effect of melatonin and vitamin e on diabetes-induced learning and memory impairment in rats
    • M. Tuzcu, and G. Baydas Effect of melatonin and vitamin E on diabetes-induced learning and memory impairment in rats Eur. J. Pharmacol. 537 2006 106 110
    • (2006) Eur. J. Pharmacol. , vol.537 , pp. 106-110
    • Tuzcu, M.1    Baydas, G.2
  • 57
    • 0024348438 scopus 로고
    • Ethanol-induced changes in lipid peroxidation and glutathione content in rat brain
    • DOI 10.1016/0376-8716(89)90085-9
    • M. Uysal, G. Kutalp, G. Ozdemirler, and G. Ayka Ethanol-induced changes in lipid peroxidation and glutathione content in rat brain Drug Alcohol Depend. 23 1989 227 230 (Pubitemid 19148666)
    • (1989) Drug and Alcohol Dependence , vol.23 , Issue.3 , pp. 227-230
    • Uysal, M.1    Kutalp, G.2    Ozdemirler, G.3    Aykac, G.4
  • 58
    • 0013914976 scopus 로고
    • Mechanism of lipid peroxide formation in animals
    • E.D. Wills Mechanism of lipid peroxide formation in animals Biochem. J. 99 1965 667 676
    • (1965) Biochem. J. , vol.99 , pp. 667-676
    • Wills, E.D.1
  • 59
    • 9644268904 scopus 로고    scopus 로고
    • Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults
    • DOI 10.1016/j.nbd.2004.08.006, PII S0969996104001913
    • D.F. Wozniak, R.E. Hartman, M.P. Boyle, S.K. Vogt, A.R. Brooks, T. Tenkova, C. Young, J.W. Olney, and L.J. Muglia Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults Neurobiol. Dis. 17 2004 403 414 (Pubitemid 39574874)
    • (2004) Neurobiology of Disease , vol.17 , Issue.3 , pp. 403-414
    • Wozniak, D.F.1    Hartman, R.E.2    Boyle, M.P.3    Vogt, S.K.4    Brooks, A.R.5    Tenkova, T.6    Young, C.7    Olney, J.W.8    Muglia, L.J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.