α-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons

Neuropharmacology

Volumn 47, Issue 6, 2004, Pages 904-915

  Osakada, Fumitaka ^a   Hashino, Asami ^a   Kume, Toshiaki ^a   Katsuki, Hiroshi ^a   Kaneko, Shuji ^a   Akaike, Akinori ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Neuroprotection; Non antioxidant function; Oxidative stress; Tocotrienol

Indexed keywords

ALPHA TOCOPHEROL DERIVATIVE; ALPHA TOCOTRIENOL; BUTHIONINE SULFOXIMINE; DELTA TOCOTRIENOL; DNA FRAGMENT; EDIBLE OIL; GAMMA TOCOTRIENOL; HYDROGEN PEROXIDE; LINSIDOMINE; NITRIC OXIDE DONOR; PALM OIL; PARAQUAT; PROTEIN KINASE INHIBITOR; S NITROSOCYSTEINE; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL STRUCTURE; CONTROLLED STUDY; CORPUS STRIATUM; DNA CLEAVAGE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG PURIFICATION; FETUS; FRACTIONATION; GLUTATHIONE METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIMETABOLITES; ANTIOXIDANTS; APOPTOSIS; BISBENZIMIDE; BUTHIONINE SULFOXIMINE; CARCINOGENS; CELL SURVIVAL; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLUORESCENT DYES; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; L-LACTATE DEHYDROGENASE; NEOSTRIATUM; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, WISTAR; STAUROSPORINE; TETRAZOLIUM SALTS; THIAZOLES; VITAMIN E;

EID: 7444250188     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2004.06.029     Document Type: Article

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