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Volumn 64, Issue 8, 2012, Pages 676-683

NOS-2 signaling and cancer therapy

Author keywords

drug discovery; human molecular disease; nitric oxide; nitrosative stress; signaling

Indexed keywords

CD163 ANTIGEN; CD31 ANTIGEN; CD68 ANTIGEN; CD8 ANTIGEN; CYCLIC GMP; DNA VACCINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GAMMA INTERFERON; GELATINASE B; GUANYLATE CYCLASE; HLA DR ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 4; ISOBUTYLMETHYLXANTHINE; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; N6 (1 IMINOETHYL)LYSINE; N6 (1 IMINOETHYL)LYSINE 5 TETRAZOLE AMIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; REACTIVE NITROGEN SPECIES; SC 51; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; ZAPRINAST;

EID: 84864243363     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1057     Document Type: Review
Times cited : (47)

References (90)
  • 1
    • 0038571272 scopus 로고    scopus 로고
    • Nitric oxide (NO) - Biogeneration, regulation, and relevence to human diseases
    • a1-d305
    • Bian, K., and, Murad, F., (2003) Nitric oxide (NO) - biogeneration, regulation, and relevance to human diseases. Front Biosci. 8, d264-d278. (Pubitemid 39069977)
    • (2003) Frontiers in Bioscience , vol.8
    • Bian, K.1    Murad, F.2
  • 2
    • 46349086870 scopus 로고    scopus 로고
    • Vascular system: Role of nitric oxide in cardiovascular diseases
    • Bian, K., Doursout, M. F., and, Murad, F., (2008) Vascular system: role of nitric oxide in cardiovascular diseases. J. Clin. Hypertens. (Greenwich) 10, 304-310.
    • (2008) J. Clin. Hypertens. (Greenwich) , vol.10 , pp. 304-310
    • Bian, K.1    Doursout, M.F.2    Murad, F.3
  • 5
    • 0034957025 scopus 로고    scopus 로고
    • Nitric oxide suppresses IL-8 transcription by inhibiting c-Jun N-terminal kinase-induced AP-1 activation
    • DOI 10.1006/excr.2001.5218
    • Natarajan, R., Gupta, S., Fisher, B. J., Ghosh, S., and, Fowler, A. A., III, (2001) Nitric oxide suppresses IL-8 transcription by inhibiting c-Jun N-terminal kinase-induced AP-1 activation. Exp. Cell Res. 266, 203-212. (Pubitemid 32579225)
    • (2001) Experimental Cell Research , vol.266 , Issue.2 , pp. 203-212
    • Natarajan, R.1    Gupta, S.2    Fisher, B.J.3    Ghosh, S.4    Fowler III, A.A.5
  • 7
    • 0037137226 scopus 로고    scopus 로고
    • Nitric oxide-mediated inhibition of Hdm2-p53 binding
    • DOI 10.1021/bi026262q
    • Schonhoff, C. M., Daou, M. C., Jones, S. N., Schiffer, C. A., and, Ross, A. H., (2002) Nitric oxide-mediated inhibition of Hdm2-p53 binding. Biochemistry 41, 13570-13574. (Pubitemid 35332692)
    • (2002) Biochemistry , vol.41 , Issue.46 , pp. 13570-13574
    • Schonhoff, C.M.1    Daou, M.-C.2    Jones, S.N.3    Schiffer, C.A.4    Ross, A.H.5
  • 9
    • 5644278790 scopus 로고    scopus 로고
    • Endogenous nitration of iron regulatory protein-1 (IRP-1) in nitric oxide-producing murine macrophages: Further insight into the mechanism of nitration in vivo and its impact on IRP-1 functions
    • DOI 10.1074/jbc.M401889200
    • Gonzalez, D., Drapier, J. C., and, Bouton, C., (2004) Endogenous nitration of iron regulatory protein-1 (IRP-1) in nitric oxide-producing murine macrophages: further insight into the mechanism of nitration in vivo and its impact on IRP-1 functions. J. Biol. Chem. 279, 43345-43351. (Pubitemid 39372229)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.41 , pp. 43345-43351
    • Gonzalez, D.1    Drapier, J.-C.2    Bouton, C.3
  • 10
    • 0016806024 scopus 로고
    • Increased particulate and decreased soluble guanylate cyclase activity in regenerating liver, fetal liver, and hepatoma
    • Kimura, H., and, Murad, F., (1975) Increased particulate and decreased soluble guanylate cyclase activity in regenerating liver, fetal liver, and hepatoma. Proc. Natl. Acad. Sci. USA 72, 1965-1969.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 1965-1969
    • Kimura, H.1    Murad, F.2
  • 11
    • 0017071850 scopus 로고
    • Urinary excretion of cyclic guanosine 3':5'-monophosphate and cyclic adenosine 3':5'-monophosphate in rats bearing transplantable liver and kidney tumors
    • Criss, W. E., and, Murad, F., (1976) Urinary excretion of cyclic guanosine 3':5'-monophosphate and cyclic adenosine 3':5'-monophosphate in rats bearing transplantable liver and kidney tumors. Cancer Res. 36, 1714-1716.
    • (1976) Cancer Res. , vol.36 , pp. 1714-1716
    • Criss, W.E.1    Murad, F.2
  • 14
    • 0025802065 scopus 로고
    • Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase
    • Bredt, D. S., Hwang, P. M., Glatt, C. E., Lowenstein, C., Reed, R. R., and, Snyder, S. H., (1991) Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature 351, 714-718. (Pubitemid 21896670)
    • (1991) Nature , vol.351 , Issue.6329 , pp. 714-718
    • Bredt, D.S.1    Hwang, P.M.2    Glatt, C.E.3    Lowenstein, C.4    Reed, R.R.5    Snyder, S.H.6
  • 15
    • 0026342264 scopus 로고
    • Purification and characterization of a human NO synthase
    • Schmidt, H. H., and, Murad, F., (1991) Purification and characterization of a human NO synthase. Biochem. Biophys. Res. Commun. 181, 1372-1377.
    • (1991) Biochem. Biophys. Res. Commun. , vol.181 , pp. 1372-1377
    • Schmidt, H.H.1    Murad, F.2
  • 16
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls, and controls
    • DOI 10.1016/0092-8674(94)90266-6
    • Nathan, C., and, Xie, Q. W., (1994) Nitric oxide synthases: roles, tolls, and controls. Cell 78, 915-918. (Pubitemid 24292319)
    • (1994) Cell , vol.78 , Issue.6 , pp. 915-918
    • Nathan, C.1    Xie, Q.-W.2
  • 17
    • 0026498665 scopus 로고
    • Cloning and expression of a cDNA encoding human endothelium-derived relating factor/nitric oxide synthase
    • Janssens, S. P., Simouchi, A., Quertermous, T., Bloch, D. B., and, Bloch, K. D., (1992) Cloning and expression of a cDNA encoding human endothelium-derived relating factor/nitric oxide synthase. J. Biol. Chem. 267, 22694.
    • (1992) J. Biol. Chem. , vol.267 , pp. 22694
    • Janssens, S.P.1    Simouchi, A.2    Quertermous, T.3    Bloch, D.B.4    Bloch, K.D.5
  • 19
    • 0027255749 scopus 로고
    • Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide
    • Xie, Q. W., Whisnant, R., and, Nathan, C., (1993) Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide. J. Exp. Med. 177, 1779-1784. (Pubitemid 23146145)
    • (1993) Journal of Experimental Medicine , vol.177 , Issue.6 , pp. 1779-1784
    • Xie, Q.-W.1    Whisnant, R.2    Nathan, C.3
  • 20
    • 0035882245 scopus 로고    scopus 로고
    • Diversity of endotoxin-induced nitrotyrosine formation in macrophage-endothelium-rich organs
    • DOI 10.1016/S0891-5849(01)00600-1, PII S0891584901006001
    • Bian, K., and, Murad, F., (2001) Diversity of endotoxin-induced nitrotyrosine formation in macrophage-endothelium-rich organs. Free Radic. Biol. Med. 31, 421-429. (Pubitemid 32728429)
    • (2001) Free Radical Biology and Medicine , vol.31 , Issue.4 , pp. 421-429
    • Bian, K.1    Murad, F.2
  • 21
    • 0035062427 scopus 로고    scopus 로고
    • Down-regulation of inducible nitric-oxide synthase (NOS-2) during parasite-induced gut inflammation: A path to identify a selective NOS-2 inhibitor
    • Bian, K., Harari, Y., Zhong, M., Lai, M., Castro, G., Weisbrodt, N., and, Murad, F., (2001) Down-regulation of inducible nitric-oxide synthase (NOS-2) during parasite-induced gut inflammation: a path to identify a selective NOS-2 inhibitor. Mol. Pharmacol. 59, 939-947. (Pubitemid 32274023)
    • (2001) Molecular Pharmacology , vol.59 , Issue.4 , pp. 939-947
    • Bian, K.1    Harari, Y.2    Zhong, M.3    Lai, M.4    Castro, G.5    Weisbrodt, N.6    Murad, F.7
  • 22
    • 0037042185 scopus 로고    scopus 로고
    • Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver
    • DOI 10.1016/S0304-3835(01)00859-X, PII S030438350100859X
    • Kondo, S., Toyokuni, S., Tsuruyama, T., Ozeki, M., Tachibana, T., Echizenya, M., Hiai, H., Onodera, H., and, Imamura, M., (2002) Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver. Cancer Lett. 179, 87-93. (Pubitemid 34195657)
    • (2002) Cancer Letters , vol.179 , Issue.1 , pp. 87-93
    • Kondo, S.1    Toyokuni, S.2    Tsuruyama, T.3    Ozeki, M.4    Tachibana, T.5    Echizenya, M.6    Hiai, H.7    Onodera, H.8    Imamura, M.9
  • 23
    • 0034829965 scopus 로고    scopus 로고
    • Immunohistochemical study of inducible nitric oxide synthase in skin cancers
    • DOI 10.1034/j.1600-0560.2001.028009476.x
    • Kagoura, M., Matsui, C., Toyoda, M., and, Morohashi, M., (2001) Immunohistochemical study of inducible nitric oxide synthase in skin cancers. J. Cutan Pathol. 28, 476-481. (Pubitemid 32881885)
    • (2001) Journal of Cutaneous Pathology , vol.28 , Issue.9 , pp. 476-481
    • Kagoura, M.1    Matsui, C.2    Toyoda, M.3    Morohashi, M.4
  • 24
    • 0035368275 scopus 로고    scopus 로고
    • Nitric oxide: Relation to integrity, injury, and healing of the gastric mucosa
    • DOI 10.1002/jemt.1100
    • Calatayud, S., Barrachina, D., and, Esplugues, J. V., (2001) Nitric oxide: relation to integrity, injury, and healing of the gastric mucosa. Microsc. Res. Tech. 53, 325-335. (Pubitemid 32494582)
    • (2001) Microscopy Research and Technique , vol.53 , Issue.5 , pp. 325-335
    • Calatayud, S.1    Barrachina, D.2    Esplugues, J.V.3
  • 26
    • 0031795484 scopus 로고    scopus 로고
    • Nitric oxide in neurodegeneration
    • Dawson, V. L., and, Dawson, T. M., (1998) Nitric oxide in neurodegeneration. Prog. Brain Res. 118, 215-229. (Pubitemid 28530669)
    • (1998) Progress in Brain Research , vol.118 , pp. 215-229
    • Dawson, V.L.1    Dawson, T.M.2
  • 27
    • 0035283321 scopus 로고    scopus 로고
    • Expression and function of inducible nitric oxide synthase in neurons
    • DOI 10.1016/S0165-5728(01)00246-6, PII S0165572801002466
    • Heneka, M. T., and, Feinstein, D. L., (2001) Expression and function of inducible nitric oxide synthase in neurons. J. Neuroimmunol. 114, 8-18. (Pubitemid 32184720)
    • (2001) Journal of Neuroimmunology , vol.114 , Issue.1-2 , pp. 8-18
    • Heneka, M.T.1    Feinstein, D.L.2
  • 28
    • 0032998811 scopus 로고    scopus 로고
    • Nitric oxide synthase and cyclooxygenases: Distribution, regulation, and intervention in arthritis
    • DOI 10.1097/00002281-199905000-00009
    • Amin, A. R., Attur, M., and, Abramson, S. B., (1999) Nitric oxide synthase and cyclooxygenases: distribution, regulation, and intervention in arthritis. Curr. Opin. Rheumatol. 11, 202-209. (Pubitemid 29257638)
    • (1999) Current Opinion in Rheumatology , vol.11 , Issue.3 , pp. 202-209
    • Amin, A.R.1    Attur, M.2    Abramson, S.B.3
  • 29
    • 0034965383 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions
    • Liu, J. S., Zhao, M. L., Brosnan, C. F., and, Lee, S. C., (2001) Expression of inducible nitric oxide synthase and nitrotyrosine in multiple sclerosis lesions. Am. J. Pathol. 158, 2057-2066. (Pubitemid 32545191)
    • (2001) American Journal of Pathology , vol.158 , Issue.6 , pp. 2057-2066
    • Liu, J.S.-H.1    Zhao, M.-L.2    Brosnan, C.F.3    Lee, S.C.4
  • 30
    • 0036316765 scopus 로고    scopus 로고
    • Angiogenic markers, neovascularization and malignant deformation of Barrett's esophagus
    • DOI 10.1046/j.1442-2050.2002.00212.x
    • Wilson, K. T., (2002) Angiogenic markers, neovascularization and malignant deformation of Barrett's esophagus. Dis. Esophagus 15, 16-21. (Pubitemid 34811994)
    • (2002) Diseases of the Esophagus , vol.15 , Issue.1 , pp. 16-21
    • Wilson, K.T.1
  • 31
    • 0036136308 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression in laryngeal neoplasia: Correlation with angiogenesis
    • DOI 10.1002/hed.10045
    • Franchi, A., Gallo, O., Paglierani, M., Sardi, I., Magnelli, L., Masini, E., and, Santucci, M., (2002) Inducible nitric oxide synthase expression in laryngeal neoplasia: correlation with angiogenesis. Head Neck 24, 16-23. (Pubitemid 34013850)
    • (2002) Head and Neck , vol.24 , Issue.1 , pp. 16-23
    • Franchi, A.1    Gallo, O.2    Paglierani, M.3    Sardi, I.4    Magnelli, L.5    Masini, E.6    Santucci, M.7
  • 32
    • 0036182269 scopus 로고    scopus 로고
    • Association of a functional inducible nitric oxide synthase promoter variant with complications in type 2 diabetes
    • DOI 10.1007/s00109-001-0287-1
    • Morris, B. J., Markus, A., Glenn, C. L., Adams, D. J., Colagiuri, S., and, Wang, L., (2002) Association of a functional inducible nitric oxide synthase promoter variant with complications in type 2 diabetes. J. Mol. Med. 80, 96-104. (Pubitemid 34169817)
    • (2002) Journal of Molecular Medicine , vol.80 , Issue.2 , pp. 96-104
    • Morris, B.J.1    Markus, A.M.2    Glenn, C.L.3    Adams, D.J.4    Colagiuri, S.5    Wang, X.6
  • 38
    • 70349538626 scopus 로고    scopus 로고
    • Monocytes and macrophages as cellular targets in liver fibrosis
    • Heymann, F., Trautwein, C., and, Tacke, F., (2009) Monocytes and macrophages as cellular targets in liver fibrosis. Inflam. Allergy Drug Targets 8, 307-318.
    • (2009) Inflam. Allergy Drug Targets , vol.8 , pp. 307-318
    • Heymann, F.1    Trautwein, C.2    Tacke, F.3
  • 39
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard, J. W., (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer 4, 71-78. (Pubitemid 38082155)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.1 , pp. 71-78
    • Pollard, J.W.1
  • 40
    • 78651062856 scopus 로고    scopus 로고
    • Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice
    • Liu, G., Ma, H., Qiu, L., Li, L., Cao, Y., Ma, J., and, Zhao, Y., (2011) Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice. Immunol. Cell Biol. 89, 130-142.
    • (2011) Immunol. Cell Biol. , vol.89 , pp. 130-142
    • Liu, G.1    Ma, H.2    Qiu, L.3    Li, L.4    Cao, Y.5    Ma, J.6    Zhao, Y.7
  • 41
    • 67650485985 scopus 로고    scopus 로고
    • Alternative activation of macrophages: An immunologic functional perspective
    • Martinez, F. O., Helming, L., and, Gordon, S., (2009) Alternative activation of macrophages: an immunologic functional perspective. Annu. Rev. Immunol. 27, 451-483.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 451-483
    • Martinez, F.O.1    Helming, L.2    Gordon, S.3
  • 42
    • 17344374016 scopus 로고    scopus 로고
    • Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells
    • Morris, S. M., Jr., Kepka-Lenhart, D., and, Chen, L. C., (1998) Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells. Am. J. Physiol. 275, E740-E747.
    • (1998) Am. J. Physiol. , vol.275
    • Morris Jr., S.M.1    Kepka-Lenhart, D.2    Chen, L.C.3
  • 43
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • DOI 10.1038/nri978
    • Gordon, S., (2003) Alternative activation of macrophages. Nat. Rev. Immunol. 3, 23-35. (Pubitemid 37328697)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 44
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • DOI 10.1016/S0140-6736(00)04046-0
    • Balkwill, F., and, Mantovani, A., (2001) Inflammation and cancer: back to Virchow? Lancet 357, 539-545. (Pubitemid 32173595)
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 45
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • DOI 10.1002/path.1027
    • Bingle, L., Brown, N. J., and, Lewis, C. E., (2002) The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J. Pathol. 196, 254-265. (Pubitemid 34189413)
    • (2002) Journal of Pathology , vol.196 , Issue.3 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 46
    • 77952937103 scopus 로고    scopus 로고
    • The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
    • Ma, J., Liu, L., Che, G., Yu, N., Dai, F., and, You, Z., (2010) The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time. BMC Cancer 10, 112.
    • (2010) BMC Cancer , vol.10 , pp. 112
    • Ma, J.1    Liu, L.2    Che, G.3    Yu, N.4    Dai, F.5    You, Z.6
  • 47
    • 11844277698 scopus 로고    scopus 로고
    • Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease
    • Sinha, P., Clements, V. K., and, Ostrand-Rosenberg, S., (2005) Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. J. Immunol. 174, 636-645. (Pubitemid 40094255)
    • (2005) Journal of Immunology , vol.174 , Issue.2 , pp. 636-645
    • Sinha, P.1    Clements, V.K.2    Ostrand-Rosenberg, S.3
  • 48
    • 0034650833 scopus 로고    scopus 로고
    • Autocrine production of IL-10 mediates defective IL-12 production and NF-kappaB activation in tumor-associated macrophages
    • Sica, A., Saccani, A., Bottazzi, B., Polentarutti, N., Vecchi, A., van Damme, J., and, Mantovani, A., (2000) Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages. J. Immunol. 164, 762-767. (Pubitemid 30043699)
    • (2000) Journal of Immunology , vol.164 , Issue.2 , pp. 762-767
    • Sica, A.1    Saccani, A.2    Bottazzi, B.3    Polentarutti, N.4    Vecchi, A.5    Van Damme, J.6    Mantovani, A.7
  • 49
    • 17144398046 scopus 로고    scopus 로고
    • Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
    • Guiducci, C., Vicari, A. P., Sangaletti, S., Trinchieri, G., and, Colombo, M. P., (2005) Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res. 65, 3437-3446. (Pubitemid 40524630)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3437-3446
    • Guiducci, C.1    Vicari, A.P.2    Sangaletti, S.3    Trinchieri, G.4    Colombo, M.P.5
  • 53
    • 33745559710 scopus 로고    scopus 로고
    • The role of nitric oxide in tumour progression
    • DOI 10.1038/nrc1910, PII N1910
    • Fukumura, D., Kashiwagi, S., and, Jain, R. K., (2006) The role of nitric oxide in tumour progression. Nat. Rev. Cancer 6, 521-534. (Pubitemid 43980541)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.7 , pp. 521-534
    • Fukumura, D.1    Kashiwagi, S.2    Jain, R.K.3
  • 54
    • 0028873889 scopus 로고
    • Expression of nitric oxide synthase in human central nervous system tumors
    • Cobbs, C. S., Brenman, J. E., Aldape, K. D., Bredt, D. S., and, Israel, M. A., (1995) Expression of nitric oxide synthase in human central nervous system tumors. Cancer Res. 55, 727-730.
    • (1995) Cancer Res. , vol.55 , pp. 727-730
    • Cobbs, C.S.1    Brenman, J.E.2    Aldape, K.D.3    Bredt, D.S.4    Israel, M.A.5
  • 55
    • 0034028131 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase isozymes (NOS I-III) by immunohistochemistry and DNA in situ hybridization. Correlation with macrophage presence, vascular endothelial growth factor (VEGF) and oedema volumetric data in 220 glioblastomas
    • Ludwig, H. C., Feiz-Erfan, I., Bockermann, V., Behnke-Mursch, J., Schallock, K., and, Markakis, E., (2000) Expression of nitric oxide synthase isozymes (NOS I-III) by immunohistochemistry and DNA in situ hybridization. Correlation with macrophage presence, vascular endothelial growth factor (VEGF) and oedema volumetric data in 220 glioblastomas. Anticancer Res. 20, 299-304. (Pubitemid 30189770)
    • (2000) Anticancer Research , vol.20 , Issue.1 , pp. 299-304
    • Ludwig, H.C.1    Feiz-Erfan, I.2    Bockermann, V.3    Behnke-Mursch, J.4    Schallock, K.5    Markakis, E.6
  • 56
    • 0035178578 scopus 로고    scopus 로고
    • Nitric oxide synthase expression of oligodendrogliomas
    • Broholm, H., Braendstrup, O., and, Lauritzen, M., (2001) Nitric oxide synthase expression of oligodendrogliomas. Clin. Neuropathol. 20, 233-238. (Pubitemid 33081705)
    • (2001) Clinical Neuropathology , vol.20 , Issue.6 , pp. 233-238
    • Broholm, H.1    Braendstrup, O.2    Lauritzen, M.3
  • 58
    • 0032485518 scopus 로고    scopus 로고
    • The expression of nitric oxide synthases in human brain tumours and peritumoral areas
    • DOI 10.1016/S0022-510X(97)00315-8, PII S0022510X97003158
    • Bakshi, A., Nag, T. C., Wadhwa, S., Mahapatra, A. K., and, Sarkar, C., (1998) The expression of nitric oxide synthases in human brain tumours and peritumoral areas. J. Neurol. Sci. 155, 196-203. (Pubitemid 28139021)
    • (1998) Journal of the Neurological Sciences , vol.155 , Issue.2 , pp. 196-203
    • Bakshi, A.1    Nag, T.C.2    Wadhwa, S.3    Mahapatra, A.K.4    Sarkar, C.5
  • 60
    • 0032832211 scopus 로고    scopus 로고
    • Discovery of some of the biological effects of nitric oxide and its role in cell signaling
    • DOI 10.1023/A:1020265417394
    • Murad, F., (1999) Discovery of some of the biological effects of nitric oxide and its role in cell signaling. Biosci. Rep. 19, 133-154. (Pubitemid 29455841)
    • (1999) Bioscience Reports , vol.19 , Issue.3 , pp. 133-154
    • Murad, F.1    Dunn, J.S.2
  • 62
    • 0034928756 scopus 로고    scopus 로고
    • NO, nitrotyrosine, and cyclic GMP in signal transduction
    • Hanafy, K. A., Krumenacker, J. S., and, Murad, F., (2001) NO, nitrotyrosine, and cyclic GMP in signal transduction. Med. Sci. Monit. 7, 801-819. (Pubitemid 32691766)
    • (2001) Medical Science Monitor , vol.7 , Issue.4 , pp. 801-819
    • Hanafy, K.A.1    Krumenacker, J.S.2    Murad, F.3
  • 63
    • 0034485823 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival
    • Ekmekcioglu, S., Ellerhorst, J., Smid, C. M., Prieto, V. G., Munsell, M., Buzaid, A. C., and, Grimm, E. A., (2000) Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival. Clin. Cancer Res. 6, 4768-4775. (Pubitemid 32110418)
    • (2000) Clinical Cancer Research , vol.6 , Issue.12 , pp. 4768-4775
    • Ekmekcioglu, S.1    Ellerhorst, J.2    Smid, C.M.3    Prieto, V.G.4    Munsell, M.5    Buzaid, A.C.6    Grimm, E.A.7
  • 69
    • 0032556905 scopus 로고    scopus 로고
    • Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
    • DOI 10.1038/34923
    • Eiserich, J. P., Hristova, M., Cross, C. E., Jones, A. D., Freeman, B. A., Halliwell, B., and, van der Vliet, A., (1998) Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 391, 393-397. (Pubitemid 28093514)
    • (1998) Nature , vol.391 , Issue.6665 , pp. 393-397
    • Eiserich, J.P.1    Hristova, M.2    Cross, C.E.3    Jones, A.D.4    Freeman, B.A.5    Halliwell, B.6    Van Der Vliet, A.7
  • 70
    • 0033520499 scopus 로고    scopus 로고
    • Eosinophil peroxidase nitrates protein tyrosyl residues. Implications for oxidative damage by nitrating intermediates in eosinophilic inflammatory disorders
    • Wu, W., Chen, Y., and, Hazen, S. L., (1999) Eosinophil peroxidase nitrates protein tyrosyl residues. Implications for oxidative damage by nitrating intermediates in eosinophilic inflammatory disorders. J. Biol. Chem. 274, 25933-25944.
    • (1999) J. Biol. Chem. , vol.274 , pp. 25933-25944
    • Wu, W.1    Chen, Y.2    Hazen, S.L.3
  • 71
    • 0035577764 scopus 로고    scopus 로고
    • Min/+ mice by inhibiting nitric oxide production
    • Ahn, B., and, Ohshima, H., (2001) Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production. Cancer Res. 61, 8357-8360. (Pubitemid 33131104)
    • (2001) Cancer Research , vol.61 , Issue.23 , pp. 8357-8360
    • Ahn, B.1    Ohshima, H.2
  • 72
    • 4344691283 scopus 로고    scopus 로고
    • Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase
    • DOI 10.1136/gut.2003.030684
    • Nam, K. T., Oh, S. Y., Ahn, B., Kim, Y. B., Jang, D. D., Yang, K. H., Hahm, K. B., and, Kim, D. Y., (2004) Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase. Gut 53, 1250-1255. (Pubitemid 39120106)
    • (2004) Gut , vol.53 , Issue.9 , pp. 1250-1255
    • Nam, K.T.1    Oh, S.-Y.2    Ahn, B.3    Kim, Y.B.4    Jang, D.D.5    Yang, K.-H.6    Hahm, K.-B.7    Kim, D.-Y.8
  • 75
    • 0036144387 scopus 로고    scopus 로고
    • Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor
    • Rao, C. V., Indranie, C., Simi, B., Manning, P. T., Connor, J. R., and, Reddy, B. S., (2002) Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor. Cancer Res. 62, 165-170. (Pubitemid 34074001)
    • (2002) Cancer Research , vol.62 , Issue.1 , pp. 165-170
    • Rao, C.V.1    Indranie, C.2    Simi, B.3    Manning, P.T.4    Connor, J.R.5    Reddy, B.S.6
  • 76
    • 0030877443 scopus 로고    scopus 로고
    • Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: Studies with 1400W, a novel inhibitor
    • Thomsen, L. L., Scott, J. M., Topley, P., Knowles, R. G., Keerie, A. J., and, Frend, A. J., (1997) Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor. Cancer Res. 57, 3300-3304. (Pubitemid 27351750)
    • (1997) Cancer Research , vol.57 , Issue.15 , pp. 3300-3304
    • Thomsen, L.L.1    Scott, J.M.J.2    Topley, P.3    Knowles, R.G.4    Keerie, A.-J.5    Frend, A.J.6
  • 77
    • 77953016756 scopus 로고    scopus 로고
    • Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2
    • Ohtsu, N., Takaoka, K., Segawa, E., Hashitani, S., Noguchi, K., Kishimoto, H., and, Urade, M., (2010) Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2. Oncol Rep. 24, 31-36.
    • (2010) Oncol Rep. , vol.24 , pp. 31-36
    • Ohtsu, N.1    Takaoka, K.2    Segawa, E.3    Hashitani, S.4    Noguchi, K.5    Kishimoto, H.6    Urade, M.7
  • 79
    • 53149114868 scopus 로고    scopus 로고
    • Interaction of caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells
    • Shen, J., Lee, W., Li, Y., Lau, C. F., Ng, K. M., Fung, M. L., and, Liu, K. J., (2008) Interaction of caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells. J. Neurochem. 107, 478-487.
    • (2008) J. Neurochem. , vol.107 , pp. 478-487
    • Shen, J.1    Lee, W.2    Li, Y.3    Lau, C.F.4    Ng, K.M.5    Fung, M.L.6    Liu, K.J.7
  • 80
    • 0028929559 scopus 로고
    • Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells
    • Xie, K., Huang, S., Dong, Z., Juang, S. H., Gutman, M., Xie, Q. W., Nathan, C., and, Fidler, I. J., (1995) Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. J. Exp. Med. 181, 1333-1343.
    • (1995) J. Exp. Med. , vol.181 , pp. 1333-1343
    • Xie, K.1    Huang, S.2    Dong, Z.3    Juang, S.H.4    Gutman, M.5    Xie, Q.W.6    Nathan, C.7    Fidler, I.J.8
  • 81
    • 0036481660 scopus 로고    scopus 로고
    • Microencapsulated iNOS-expressing cells cause tumor suppression in mice
    • Xu, W., Liu, L., and, Charles, I. G., (2002) Microencapsulated iNOS-expressing cells cause tumor suppression in mice. FASEB J. 16, 213-215.
    • (2002) FASEB J. , vol.16 , pp. 213-215
    • Xu, W.1    Liu, L.2    Charles, I.G.3
  • 83
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T., (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol Methods 65, 55-63. (Pubitemid 14203433)
    • (1983) Journal of Immunological Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 85
    • 0035300431 scopus 로고    scopus 로고
    • Nitric oxide synthase II gene disruption: Implications for tumor growth and vascular endothelial growth factor production
    • Konopka, T. E., Barker, J. E., Bamford, T. L., Guida, E., Anderson, R. L., and, Stewart, A. G., (2001) Nitric oxide synthase II gene disruption: implications for tumor growth and vascular endothelial growth factor production. Cancer Res. 61, 3182-3187. (Pubitemid 32691973)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 3182-3187
    • Konopka, T.E.1    Barker, J.E.2    Bamford, T.L.3    Guida, E.4    Anderson, R.L.5    Stewart, A.G.6
  • 86
    • 33646063560 scopus 로고    scopus 로고
    • Tumour overexpression of inducible nitric oxide synthase (iNOS) increases angiogenesis and may modulate the anti-tumour effects of the vascular disrupting agent ZD6126
    • Cullis, E. R., Kalber, T. L., Ashton, S. E., Cartwright, J. E., Griffiths, J. R., Ryan, A. J., and, Robinson, S. P., (2006) Tumour overexpression of inducible nitric oxide synthase (iNOS) increases angiogenesis and may modulate the anti-tumour effects of the vascular disrupting agent ZD6126. Microvasc. Res. 71, 76-84.
    • (2006) Microvasc. Res. , vol.71 , pp. 76-84
    • Cullis, E.R.1    Kalber, T.L.2    Ashton, S.E.3    Cartwright, J.E.4    Griffiths, J.R.5    Ryan, A.J.6    Robinson, S.P.7
  • 88
    • 2542619027 scopus 로고    scopus 로고
    • Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells
    • DOI 10.1158/0008-5472.CAN-03-3740
    • Deguchi, A., Thompson, W. J., and, Weinstein, I. B., (2004) Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells. Cancer Res. 64, 3966-3973. (Pubitemid 38697311)
    • (2004) Cancer Research , vol.64 , Issue.11 , pp. 3966-3973
    • Deguchi, A.1    Thompson, W.J.2    Weinstein, I.B.3
  • 89
    • 77951150727 scopus 로고    scopus 로고
    • Protein kinase G type Ialpha activity in human ovarian cancer cells significantly contributes to enhanced Src activation and DNA synthesis/cell proliferation
    • Leung, E. L., Wong, J. C., Johlfs, M. G., Tsang, B. K., and, Fiscus, R. R., (2010) Protein kinase G type Ialpha activity in human ovarian cancer cells significantly contributes to enhanced Src activation and DNA synthesis/cell proliferation. Mol. Cancer Res. 8, 578-591.
    • (2010) Mol. Cancer Res. , vol.8 , pp. 578-591
    • Leung, E.L.1    Wong, J.C.2    Johlfs, M.G.3    Tsang, B.K.4    Fiscus, R.R.5
  • 90
    • 69849089410 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines
    • Swartling, F. J., Ferletta, M., Kastemar, M., Weiss, W. A., and, Westermark, B., (2009) Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene 28, 3121-3131.
    • (2009) Oncogene , vol.28 , pp. 3121-3131
    • Swartling, F.J.1    Ferletta, M.2    Kastemar, M.3    Weiss, W.A.4    Westermark, B.5


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